Faculty Profiles - OZAKI Toshifumi

Papers - OZAKI Toshifumi

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Efficacy of Pregabalin for Patients with Neuropathic Pain and Degenerative Lumbar Disease

Tetsunaga Tomoko, Tanaka Masato, Sugimoto Yoshihisa, Misawa Haruo, Takigawa Tomoyuki, Shiozaki Yasuyuki, Osaki Syuhei, Mazaki Tetsuro, Yamane Kentarou, Ozaki Toshifumi

The Journal of the Chugoku-Shikoku Orthopaedic Association 24 ( 2 ) 325 - 329 2012

Language：Japanese Publisher：The Chugoku-Shikoku Orthopaedic Association

The anti-seizure drug, pregabalin, is used for treatment of neuropathic pain and degenerative lumbar disease. The objective of this study was to evaluate the effect of pregabalin (150-300 mg/day) in patients with chronic lower back/leg pain. We assessed 47 patients (17 men and 30 women) with an average age of 65 years (range 20 to 81 years), and an average disease duration of 87 months (range 3 to 480 months). All patients were assessed using a visual analogue scale (VAS, 0-100 mm), the Self-Rating Depression Scale (SDS, 20-80 points), and the Oswestry Disability Index (ODI, 0-100%). After 8 weeks, pregabalin improved lower back pain, leg pain, SDS and ODI significantly (P<0.01). Pain was improved significantly in the depression group as well as the normal group (P<0.01). Accepted sleepiness (51%), dizziness (19%), weight gain (16%) and rash (5%) were detected after medication. The use of the hypnotic agent was decreased in half of the cases after medication. Pregabalin is safe and effective for decreasing lower back pain and leg pain in patients with depression.

DOI： 10.11360/jcsoa.24.325

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Other Link： http://search.jamas.or.jp/link/ui/2013107559

Treatment for Atypical Basicervical Fracture of the Femur with a Coronal Shearing Fracture Line

Yamakawa Yasuaki, Noda Tomoyuki, Ozaki Toshifumi, Kinami Yo, Endo Hirosuke

The Journal of the Chugoku-Shikoku Orthopaedic Association 24 ( 2 ) 295 - 299 2012

Language：Japanese Publisher：The Chugoku-Shikoku Orthopaedic Association

We describe our experience with atypical cases of basicervical fracture of the femur. The fracture line lay between the anterior aspect of the subcapital portion and the posterior aspect of the neck base, running through the neck with a shearing fracture line as viewed in the coronal plane. We treated ten cases : seven by hemiarthroplasty and three by osteosynthesis. Bone union was obtained within six months, and there was no implant failure or complication. For diagnosis of this fracture, careful radiological assessment is important, and for effective treatment the special characteristics of this fracture should be considered. Cases of this type present difficulty with reduction and acquisition of stable fixation because of the cortical defect of the calcar or shortness of the anterior portion of the proximal fragment.

DOI： 10.11360/jcsoa.24.295

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Other Link： http://search.jamas.or.jp/link/ui/2013107554

Outcome of Treatment for Metastatic Spine Tumors with High-grade Malignancy

Mazaki Tetsuro, Tanaka Masato, Sugimoto Yoshihisa, Takigawa Tomoyuki, Tetsunaga Tomoko, Shiozaki Yasuyuki, Osaki Shuhei, Ozaki Toshifumi, Kunisada Toshiyuki, Misawa Haruo, Kataoka Masaki

The Journal of the Chugoku-Shikoku Orthopaedic Association 24 ( 2 ) 273 - 277 2012

Language：Japanese Publisher：The Chugoku-Shikoku Orthopaedic Association

We report the outcome of patients with metastatic spine tumors showing high-grade malignancy using the Tokuhashi scoring system. A retrospectively compared 21 patients with such tumors (group H) and 29 patients with spinal metastases showing low-grade malignancy (group L). There were 18 men and 3 women in group H, and 16 men and 13 women in group L, and the average patient ages were 55 years and 65 years, respectively. All of the patients were scored with the Tokuhashi scoring system and evaluated for neurological symptoms with the ASIA Impairment Scale (AIS).<br>Results : The rates of improvement in the AIS score and gait ability were almost the same in both groups. Among patients who we were able to follow postoperatively for 6 months or more, 7 in group H and 4 in group L died within 6 months. The mean survival period was 12 months in group H and 17 months in group L.<br>Conclusions : The outcome after treatment in group H was almost the same as that in group L. This may have been due to progress in the treatment of malignancy. Further studies to determine the indications for surgery in such patients are warranted.

DOI： 10.11360/jcsoa.24.273

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Other Link： http://search.jamas.or.jp/link/ui/2013107551

Cyclops Lesion after Reconstruction of the Anterior Cruciate Ligament

Fujii Masataka, Furumatsu Takayuki, Miyazawa Shinichi, Takata Naoki, Yokoyama Yusuke, Okada Yukimasa, Ozaki Toshifumi, Abe Nobuhiro

The Journal of the Chugoku-Shikoku Orthopaedic Association 24 ( 2 ) 375 - 379 2012

Language：Japanese Publisher：The Chugoku-Shikoku Orthopaedic Association

Cyclops lesions are nodular structures that form anteriorly along anterior cruciate ligament (ACL) grafts after ACL reconstruction. The purpose of this study was to investigate the occurrence rate and pathogenesis of cyclops lesions after reconstruction of the ACL. We evaluated 40 patients by follow-up arthroscopy after anatomical bi-socket ACL reconstruction with hamstring tendons. Ten patients (25%) showed cyclops lesions, and 4 of these (10%) had extension loss.<br>We investigated the pathogenesis of cyclops lesion based on the impingement theory. All patients underwent measurement of intercondylar notch dimensions and graft size by MRI. We found that a narrower notch and larger graft size were associated with the formation of cyclops lesion.

DOI： 10.11360/jcsoa.24.375

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Other Link： http://search.jamas.or.jp/link/ui/2013107567

Gene Expression and Localization of High-mobility Group Box Chromosomal Protein-1 (HMGB-1) in Human Osteoarthritic Cartilage Reviewed

Chuji Terada, Aki Yoshida, Yoshihisa Nasu, Shuji Mori, Yasuko Tomono, Masato Tanaka, Hideo K. Takahashi, Masahiro Nishibori, Toshifumi Ozaki, Keiichiro Nishida

ACTA MEDICA OKAYAMA 65 ( 6 ) 369 - 377 2011.12

Japanese guidelines for the diagnosis and management of soft tissue tumor

123 ( 3 ) 231 - 235 2011.12

臼蓋再置換術THA後に早期破綻した1例

遠藤裕介, 鉄永智紀, 藤原智洋, 藤原一夫, 三宅由晃, 尾崎敏文

日本人工関節学会誌 41 700 - 701 2011.12

Thallium-201 Scintigraphy Is an Effective Diagnostic Modality to Distinguish Malignant From Benign Soft-Tissue Tumors Reviewed

Naoaki Kawakami, Toshiyuki Kunisada, Shuhei Sato, Yuki Morimoto, Masato Tanaka, Tsuyoshi Sasaki, Shinsuke Sugihara, Hiroyuki Yanai, Susumu Kanazawa, Toshifumi Ozaki

CLINICAL NUCLEAR MEDICINE 36 ( 11 ) 982 - 986 2011.11