Faculty Profiles - OZAKI Toshifumi

Papers - OZAKI Toshifumi

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指神経に発生した巨指症を伴わないFibrolipomatous hamartomaの1例

清野正普, 武田健, 藤原智洋, 国定俊之, 尾崎敏文

中部日本整形外科災害外科学会雑誌 58 ( 秋季学会 ) 283 - 283 2015.9

滑膜肉腫患者血清から特定した滑膜肉腫特異的分泌型miRNAに関する検討

魚谷弘二, 藤原智洋, 吉田晶, 山川泰明, 大森敏規, 杉生和久, 武田健, 国定俊之, 根津悠, 川井章, 尾崎敏文

日本整形外科学会雑誌 89 ( 8 ) S1478 - S1478 2015.9

骨盤発生の放射線照射後肉腫の治療成績

武田健, 国定俊之, 藤原智洋, 魚谷弘二, 杉生和久, 尾崎敏文

中部日本整形外科災害外科学会雑誌 58 ( 秋季学会 ) 286 - 286 2015.9

骨・軟部肉腫に対する腫瘍融解アデノウイルスと放射線療法の併用効果

大森敏規, 山川泰明, 長谷井嬢, 田澤大, 尾崎修平, 杉生和久, 藤原智洋, 国定俊之, 浦田泰生, 藤原俊義, 尾崎敏文

日本整形外科学会雑誌 89 ( 8 ) S1673 - S1673 2015.9

後十字靱帯断面積は大腿骨付着部表面積に相関する

藤井政孝, 藤巻良昌, 佐々木祐介, 古松毅之, 尾崎敏文, Fu Freddie H.

日本整形外科学会雑誌 89 ( 8 ) S1554 - S1554 2015.9

Body line scannerを用いた立位rib humpの計測

小田孔明, 瀧川朋亨, 荒瀧慎也, 杉本佳久, 田中雅人, 尾崎敏文

日本整形外科学会雑誌 89 ( 8 ) S1815 - S1815 2015.9

神経線維腫症1型に合併した頸髄髄内腫瘍の1例

渡邉典行, 荒瀧慎也, 小田孔明, 魚谷弘二, 篠原健介, 鉄永倫子, 瀧川朋亨, 杉本佳久, 田中雅人, 尾崎敏文

中国・四国整形外科学会雑誌 27 ( 3 ) 446 - 446 2015.9

THA後に頻回脱臼を生じた骨盤後傾の1例

香川洋平, 遠藤裕介, 藤井洋佑, 小田孔明, 尾崎敏文

中国・四国整形外科学会雑誌 27 ( 3 ) 466 - 466 2015.9

High grade spondylolisthesisの1例

小田孔明, 杉本佳久, 瀧川朋亨, 荒瀧慎也, 田中雅人, 尾崎敏文

中部日本整形外科災害外科学会雑誌 58 ( 秋季学会 ) 249 - 249 2015.9

転写因子Mohawkは椎間板線維輪の発生・再生に重要である

中道亮, 伊藤義明, 市野瀬志津子, 酒井大輔, 舛田浩一, 尾崎敏文, 浅原弘嗣

日本整形外科学会雑誌 89 ( 8 ) S1776 - S1776 2015.9

キーンベック病に対する手術治療長期経過の1例

原田遼三, 島村安則, 井上円加, 小澤正嗣, 山川泰明, 柏原尚子, 雑賀建多, 魚谷弘二, 中原龍一, 野田知之, 西田圭一郎, 尾崎敏文

中国・四国整形外科学会雑誌 27 ( 2 ) 379 - 379 2015.9

Scoliosis correction surgery for patients with McCune-Albright syndrome using pedicle screws: a report of two cases with different characteristics and a review of the literature Reviewed

Kentaro Yamane, Masato Tanaka, Yoshihisa Sugimoto, Haruo Misawa, Toshifumi Ozaki

EUROPEAN SPINE JOURNAL 24 ( 7 ) 1362 - 1367 2015.7

Perioperative chemotherapy with ifosfamide and doxorubicin for high-grade soft tissue sarcomas in the extremities (JCOG0304). Reviewed International journal

Tanaka K, Mizusawa J, Fukuda H, Araki N, Chuman H, Takahashi M, Ozaki T, Hiruma T, Tsuchiya H, Morioka H, Hatano H, Iwamoto Y

Japanese journal of clinical oncology 45 ( 6 ) 555 - 561 2015.6

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: The efficacy of perioperative chemotherapy for soft tissue sarcomas is controversial and only a few prospective studies of pre-operative chemotherapy for soft tissue sarcomas in the extremities have been reported. We therefore carried out Phase II study of perioperative chemotherapy for patients with soft tissue sarcomas in the extremities. METHODS: Patients with Stage III non-round cell soft tissue sarcomas in the extremities were eligible. The patients were treated with pre-operative chemotherapy consisting doxorubicin 60 mg/m(2) and ifosfamide 10 g/m(2) for three courses. After the tumor resection, two additional courses of the same regimen were carried out. RESULTS: A total of 72 patients were enrolled and 70 patients were eligible. The median age of the patients was 49 years. The major pathological subtypes were synovial sarcoma in 20 and undifferentiated pleomorphic sarcoma in 17 patients. The protocol treatments were completed in 74% of the eligible cases. The 2 and 5-year progression-free survival rates were 75.7% (95% CI, 63.9-84.1%) and 63.8% (95% CI, 51.3-73.9%), respectively. The 5-year overall survival was 82.6% (95% CI, 71.3-89.7%). There was no treatment-related death. Grade 3 or 4 hematological toxicities (leukopenia and neutropenia) were observed in most of the patients. CONCLUSIONS: Although the toxicities of the regimen were significant, pre-operative chemotherapy followed by post-operative chemotherapy using doxorubicin and high-dose ifosfamide was feasible. The outcome of the trial for the patients with high-grade soft tissue sarcomas in the extremities was favorable, and this regimen is promising for further investigation. This trial was registered at the UMIN Clinical Trials Registry (www.umin.ac.jp/ctr/) as C000000096.

DOI： 10.1093/jjco/hyv042

PubMed

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骨肉腫における全生存率を予測する予後予測ノモグラムの開発

小倉浩一, 藤原智洋, 松居宏樹, 康永秀生, 平賀博明, 石井猛, 米本司, 鴨田博人, 尾崎敏文, 小澤英史, 西田佳弘, 森岡秀夫, 比留間徹, 角永茂樹, 上田孝文, 荒木信人, 中紀文, 津田祐輔, 河野博隆, 川井章

日本整形外科学会雑誌 89 ( 6 ) S1329 - S1329 2015.6