Faculty Profiles - OZAKI Toshifumi

MISC - OZAKI Toshifumi

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コラーゲン結合型BMP4の骨芽細胞に対する影響

吉田晶, 馬崎哲朗, 塩崎泰之, 古松毅之, 松川昭博, 中村真理子, 吉田靖弘, 北嶋隆, 伊藤嘉浩, 尾崎敏文

日本整形外科学会雑誌 86 ( 8 ) S1343 - S1343 2012.8

岡山大学病院卒後臨床研修プログラムにおける地域医療研修の取り組み

片岡仁美, 小比賀美香子, 三好智子, 渡辺文恵, 岩瀬敏秀, 佐藤勝, 金澤右, 尾崎敏文

医学教育 43 ( Suppl. ) 80 - 80 2012.7

p53-mediated apoptotic signaling overcomes the resistance to oncolytic adenovirus in human osteosarcoma cells

Joe Hasel, Tsuyoshi Sasaki, Hiroshi Tazawa, Yuuri Hashimoto, Toshiyuki Kunisada, Yasuo Urata, Toshifumi Ozaki, Toshiyoshi Fujiwara

CANCER RESEARCH 72 2012.4

Surgery Strategy for Pelvic Tumors

86 ( 4 ) 236 - 243 2012.4

Chondrogenic properties in ligament-derived cells

FURUMATSU Takayuki

37 ( 1 ) 114 - 115 2012.3

軟部肉腫における化学療法軟部肉腫に対する化学療法の多施設共同臨床試験(JCOG0304)

田仲和宏, 水澤純基, 福田治彦, 荒木信人, 中馬広一, 高橋満, 尾崎敏文, 比留間徹, 土屋弘行, 岩本幸英

日本整形外科学会雑誌 86 ( 2 ) S283 - S283 2012.2

Investigation of the incidence of VTE after RAO

MIYAKE Yoshiaki

55 ( 1 ) 69 - 70 2012.1

軟部肉腫の治療成績はどこまで改善したか粘液型および脱分化型脂肪肉腫の治療成績年代別治療成績の検討を中心に

穴澤卯圭, 森岡秀夫, 鈴木禎寿, 森井健司, 保坂聖一, 浅野尚文, 岩田慎太郎, 尾崎敏文, 柳川天志, 川井章, 西田佳弘, 保坂泰介, 上田孝文, 矢部啓夫, 戸山芳昭

日本整形外科学会雑誌 86 ( 9 ) 647 - 653 2012

Preclinical evaluation of telomerase-specific oncolytic virotherapy for human bone and soft tissue sarcomas

124 ( 2 ) 105 - 110 2012

The efficacy of external fixation for distal radius fractures

23 1 - 5 2012

Ankle arthrodesis with an external fixator for a large osteochondral defect of the distal tibia

23 131 - 136 2012

整形外科研修施設めぐり(7)岡山大学大学院医歯薬学総合研究科生体機能再生・再建学講座整形外科

尾崎敏文

整形外科surgical technique : 手術が見える・わかる専門誌 2 ( 2 ) 211 - 216 2012

Inner Meniscus Cells Maintain Higher Chondrogenic Phenotype Compared with Outer Meniscus Cells

Takayuki Furumatsu, Tomoko Kanazawa, Yusuke Yokoyama, Nobuhiro Abe, Toshifumi Ozaki

CONNECTIVE TISSUE RESEARCH 52 ( 6 ) 459 - 465 2011.12

Language：English Publishing type：Book review, literature introduction, etc. Publisher：INFORMA HEALTHCARE

Meniscus cells have several distinct properties in cellular morphology and extracellular matrix production. Inner meniscus cells are considered to have more chondrocytic phenotype compared with outer meniscus cells. However, the chondrogenic property of each meniscus cell has not been elucidated in detail. In this study, we investigated the difference between human inner and outer meniscus-derived cells in extracellular matrix deposition and chondrogenic potential. Monolayer-cultured inner meniscus cells showed small and ovoid shapes though slender and fibroblastic cells were obtained from outer half of human meniscus. The syntheses of type II collagen and safranin O-stained proteoglycans were increased in chondrogenic pellets derived from inner meniscus cells, rather than in outer meniscus cell-derived pellets. On the other hand, adipogenic lipid vacuoles were equally accumulated in both inner and outer meniscus cells after adipogenic treatment. Chondrogenic treatments also enhanced the expression of chondrogenic marker genes, such as Sry-type HMG box (SOX) 9, Scleraxis, and alpha 1(II) collagen, in inner meniscus cells. However, SOX9 expression was not increased in outer meniscus cells even after chondrogenic treatment. This study demonstrated that inner meniscus cells maintained higher chondrogenic potential compared with outer meniscus cells. Our results suggest that the difference between inner and outer meniscus cells in chondrogenic property might have an essential role in preserving a zone-specific meniscal feature.

DOI： 10.3109/03008207.2011.562061

Web of Science

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Development of AR Interface on Robotic Surgical System for the Minimally Invasive Knee Arthoplasty

YOKOO S., SUGITA N., NAKAJIMA Y., KATO T., ABE N., FUJIWARA K., YOKOYAMA Y., OZAKI T., SUZUKI M., KURAMOTO K., NAKASHIMA Y., MITSUISHI M.

13 ( 3 ) 340 - 341 2011.11

Mini-incision anterior slipped plating for humeral shaft fracture

KANAZAWA T., SHIMAMURA Y., NODA T., NISHIYAMA T., SAITOU T., OZAKI T.

33 ( 2 ) 318 - 321 2011.5

Clinical outcomes and problems of the treatment for traumatic hip dislocations with acetabular fractures

NODA T., SHIMAMURA Y., NISHIYAMA T., NAKAHARA R., OZAKI T., TAKAGI Y.

33 ( 2 ) 352 - 357 2011.5

Surgical treatment for distal femoral fractures after total knee arthroplasty using with the locking plate

SAITO T., NODA T., SHIMAMURA Y., NISHIYAMA T., OZAKI T., TERADA C.

33 ( 2 ) 463 - 467 2011.5

足関節周囲の骨折 (患者さんといっしょに読める整形外科病態生理32 はじめてマニュアル) -- (膝関節・足部)

野田知之, 島村安則, 尾崎敏文

整形外科看護 16 204 - 211 2011.5

Adjuvant and neoadjuvant chemotherapy (NAC) with ifosfamide (IFO) and doxorubicin hydrochloride (ADM) for high-grade soft tissue sarcomas (STS) in the extremities: Japan Clinical Oncology Group study JCOG030404.

K. Tanaka, J. Mizusawa, H. Fukuda, N. Araki, H. Chuuman, M. Takahashi, T. Ozaki, T. Hiruma, H. Tsuchiya, H. Morioka, T. Morita, T. Wada, M. Hatori, Y. Yoshida, J. Toguchida, S. Abe, A. Matsumine, R. Yokoyama, Y. Iwamoto

JOURNAL OF CLINICAL ONCOLOGY 29 ( 15 ) 2011.5

Biological reconstruction using recycled autogenous bone graft for bone and soft tissue tumors

KUNISADA Toshiyuki, MORIMOTO Yuki, ITANI Satoru, SASAKI Tsuyoshi, HASEI Jo, SUGIHARA Shinsuke, OZAKI Toshifumi

The Journal of the Japanese Orthopaedic Association 85 ( 4 ) 219 - 223 2011.4

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