研究者詳細 - 中塚　幹也

MISC - 中塚　幹也

分割表示 617 件中 101 - 120 件目／全件表示 >>

配偶子保存の必要性と課題：配偶子凍結に伴う倫理的問題

中塚幹也

臨床婦人科産科 72 ( 5 ) 424 - 428 2018年

連載第26回：不育症の基礎知識と患者支援のポイント「不育症女性の職場でのストレス」

中塚幹也

臨床助産ケア 10 ( 1 ) 93 - 96 2018年

性同一性障害（FTM）の診断と対応

中塚幹也

ホルモンと臨床 63 ( 6 ) 493 - 498 2018年

特集：LGBTを学ぶ LGBTの基礎知識

中塚幹也

健康教室 69 ( 1 ) 22 - 24 2018年

性同一性障害当事者と家族形成

中塚幹也

日本母性衛生学会 58 ( 4 ) 学3-学8 2018年

Current Multidisciplinary Approach to Fertility Preservation for Breast Cancer Patients

Yuko Takahashi, Tadahiko Shiena, Ai Sakamotob, Yuko Tsuyumuc, Ryo Yoshiokaa, Maya Unoa, Minami Hatonoa, Mariko Kochia, Kengo Kawadaa, Takahiro Tsukiokia, Takayuki Iwamotoa, Hirokuni Ikedaa, Naruto Tairaa, Junji Matsuokad, Mikiya Nakatsuka, Hiroyoshi Doiharaa

Acta Medica Okayama 72 ( 2 ) 137 - 142 2018年

胚培養士が行う不妊予防啓発授業

高山修, 大月純子, 舟橋弘晃, 舟橋弘晃, 中塚幹也, 中塚幹也

日本不妊カウンセリング学会誌 17 ( 1 ) 2018年

教職員における性別違和感を持つ児童生徒に対する意識調査学校内での啓発方法

林田桃子, 樫野千明, 藤田志保, 新井富士美, 中塚幹也

GID(性同一性障害)学会雑誌 10 ( 1 ) 106 - 106 2017年12月

High Expression of High-Mobility Group Box 1 in Menstrual Blood: Implications for Endometriosis

Keiko Shimizu, Yasuhiko Kamada, Ai Sakamoto, Miwa Matsuda, Mikiya Nakatsuka, Yuji Hiramatsu

REPRODUCTIVE SCIENCES 24 ( 11 ) 1532 - 1537 2017年11月

記述言語：英語出版者・発行元：SAGE PUBLICATIONS INC

Endometriosis is a benign gynecologic disease characterized by the presence of ectopic endometrium and associated with inflammation and immune abnormalities. However, the molecular basis for endometriosis is not well understood. To address this issue, the present study examined the expression of high-mobility group box (HMGB) 1 in menstrual blood to investigate its role in the ectopic growth of human endometriotic stromal cells (ESCs). A total of 139 patients were enrolled in this study; 84 had endometriosis and 55 were nonendometriotic gynecological patients (control). The HMGB1 levels in various fluids were measured by enzyme-linked immunosorbent assay. Expression of receptor for advanced glycation end products (RAGE) in eutopic and ectopic endometrium was assessed by immunohistochemistry, and RAGE and vascular endothelial growth factor (VEGF) messenger RNA expression in HMGB1- and lipopolysaccharide (LPS)-treated ESCs was evaluated by real-time polymerase chain reaction. The HMGB1 concentration was higher in menstrual blood than in serum or peritoneal fluid (P < .001 for both). RAGE was expressed in both normal and ectopic endometrium. Administration of 1000 ng/mL HMGB1 or coadministration of 100 ng/mL HMGB1 and 100 ng/mL LPS induced VEGF production in ESCs relative to the control (P < .05). These results suggest that menstrual fluid has naturally high levels of HMGB1 and may promote endometriosis following retrograde menstruation when complexed with other factors such as LPS by inducing inflammation and angiogenesis.

DOI： 10.1177/1933719117692042

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【学習コーナー】性同一性障害の基礎知識外来診療・看護

中塚幹也

母性衛生 58 ( 2 ) 学3-学8 2017年

連載第23回：不育症の基礎知識と患者支援のポイント「流産の原因とされること：喫煙など」

中塚幹也

臨床助産ケア 9 ( 3 ) 79 - 83 2017年

Increased Anti-HSP60 and Anti-HSP70 Antibodies in Women with Unexplained Recurrent Pregnancy Loss

Miwa Matsuda, Aiko Sasaki, Keiko Shimizu, Yasuhiko Kamada, Soichi Noguchi, Yuji Hiramatsu, Mikiya Nakatsuk

ACTA MEDICA OKAYAMA 71 ( 3 ) 201 - 208 2017年

記述言語：英語出版者・発行元：OKAYAMA UNIV MED SCHOOL

Vascular dysfunction has been reported in women with recurrent pregnancy loss (RPL). We investigated the severity of vascular dysfunction in non-pregnant women with RPL and its correlation with anti-heat shock protein (HSP) antibodies that are known to induce arteriosclerosis. We measured the serum anti-HSP60 antibodies, anti-HSP70 antibodies, and anti-phospholipid antibodies (APA) in 68 women with RPL and 29 healthy controls. Among the women with RPL, 14 had a diagnosis of antiphospholipid syndrome (APS), and in the remaining 54, the causes for RPL were unexplained. Compared to the controls, the brachial-ankle pulse wave velocity (baPWV), carotid augmentation index (cAI), and uterine artery pulsatility index (PI) were all significantly higher in the women with both APS and unexplained RPL. Compared to the controls, the anti-HSP60 antibody levels were significantly higher in the APA-positive group of women with unexplained RPL, and the anti-HSP70 antibody levels were significantly higher in APS and APA-positive group of women with unexplained RPL. However, the anti-HSP60 and anti-HSP70 antibody levels did not correlate with the values of baPWV or cAI. Our results demonstrated anti-HSP60 and anti-HSP70 antibodies are increased in women with unexplained RPL. Further studies are needed to elucidate the roles of anti-HSP antibodies and their pathophysiology in unexplained RPL.

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岡山県児童相談所に寄せられた児童虐待通告事例の背景分析（第２報）－虐待につながりやすい要因－

柴田義朗, 水嶋明子, 八木正浩, 野口正行, 佐藤俊介, 来住由樹, 中塚幹也, 児童虐待通告背景分析事業検討会

第23回岡山県保健福祉学会 158 - 161 2017年

特集１セクシュアルマイノリティの刑事弁護性同一性障害当事者がホルモン治療を継続できないことの医学的問題点

中塚幹也

季刊刑事弁護 ( 89 ) 71 - 76 2017年

大学生における「性同一性障害当事者との関係性の近さ」と理解・支援への意識

大西沙紀, 樫野千明, 北川温子, 藤田志保, 新井富士美, 中塚幹也

ＧＩＤ（性同一性障害）学会雑誌 10 ( 1 ) 25 - 40 2017年

性同一性障害に関する教育への教員の意識と実態：授業の時期，方法，専門家による支援

樫野千明, 林田桃子, 藤田志保, 新井富士美, 中塚幹也

ＧＩＤ（性同一性障害）学会雑誌 10 ( 1 ) 17 - 24 2017年

性同一性障害

中塚幹也

ホルモンと臨床 63 ( 5 ) 369 - 373 2017年

連載第25回：不育症の基礎知識と患者支援のポイント「不育症女性が思う流産とストレスとの関連」

中塚幹也

臨床助産ケア 9 ( 6 ) 89 - 91 2017年

性の多様性に対する生殖医療の役割

中塚幹也

医学のあゆみ 263 ( 4 ) 349 - 351 2017年

ＧＩＤ（性同一性障害）学会の活動と取り組むべき課題

中塚幹也

ホルモンと臨床 63 ( 4 ) 301 - 306 2017年

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