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MISC - 尾﨑　敏文

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膝関節半月板嚢腫 4 例の治療経験.

伊達宏和, 阿部信寛, 古松毅之, 迫間巧将, 尾﨑敏文

膝 32 ( 2 ) 347 - 350 2008年

特集がんの標準的治療悪性骨・軟部腫瘍.

国定俊之, 尾﨑敏文

岡山医誌 120 ( 1 ) 77 - 81 2008年

BHA , THA 後の寛骨臼骨折ケルブールプレートを用いた早期再建術について.

難波良文, 寺田忠司, 花川志郎, 三谷茂, 遠藤裕介, 尾﨑敏文

Hip Joint 34 389 - 392 2008年

骨表面形状からの点計測誤差分布推定を用いた点対応レジストレーションにおける特徴点の最適化

斎藤季, 中島義和, 杉田直彦, 藤原一夫, 阿部信寛, 尾崎敏文, 鈴木昌彦, 守屋秀繁, 井上貴之, 藏本孝一, 中島義雄, 光石衛

日本コンピュータ外科学会誌 10 ( 3 ) 2008年

低侵襲型人工膝関節置換術支援ロボットの開発

藤原一夫, 阿部信寛, 遠藤裕介, 尾崎敏文, 鈴木昌彦, 杉田直彦, 中島義和, 光石衛

日本整形外科学会雑誌 82 ( 8 ) 2008年

Predicting intraoperative vertebral rotation in patients with scoliosis using posterior elements as anatomical landmarks

Yoshihisa Sugimoto, Masato Tanaka, Kazuo Nakanishi, Haruo Misawa, Tomoyuki Takigawa, Toshifumi Ozaki

SPINE 32 ( 25 ) E761 - E763 2007年12月

記述言語：英語出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS

Study Design. A retrospective study.
Objective. To predict intraoperative vertebral rotation in patients with scoliosis using posterior elements as an atomic landmarks.
Summary of Background Data. In patients with scoliosis, accurate intraoperative vertebral rotation measurements are needed to avoid spinal cord injury caused by pedicle screw misplacement. Generally, we predict vertebral rotation by anatomic landmarks, that is, posterior elements that can be seen during surgery, such as spinous processes, transverse processes, or laminae. However, correlation between vertebral rotation and these anatomic landmarks is unclear.
Methods. Seventy-six vertebrae (T4-T12) of 17 patients with thoracic scoliosis were measured. Patients who had severe scoliosis ( > 90 degrees Cobb angle) were excluded from this study. We assessed apex and adjacent vertebrae using axial computed tomography scans taken with patients in a supine position. We measured the angle between the vertebral reference line (Ve), defined as the midline of the vertebral body, and various lines based on the following anatomic landmarks of posterior elements of the vertebrae: (a) The Spinous q process line (Sp), defined as the midline of the spinous process; (b) A bisector (Bi) of the bilateral lines that pass the depressions in the laminae to the medial apex of the transverse processes; (c) a line (Tr) perpendicular to a line which passes the bilateral transverse processes; and (d) a line (La) perpendicular to the line which passes the bilateral depressions in the laminae.
Results. The average Cobb angle in A-P radiographs was 68 degrees. The average angles between Sp, Bi, Tr, and La and the vertebral reference line were 13.6 degrees (range 0 degrees-29.2 degrees), 3.0 degrees (range 0 degrees - 9.0 degrees), 2.5 degrees (range 0 degrees - 8.1 degrees), and 4.4 degrees (range 0 degrees - 11.9 degrees), respectively.
Conclusion. The line Tr, (runs perpendicular to the line which passes the bilateral transverse processes) had the greatest correlation to the rotation of a vertebra. On the other hand, the line Sp (defined as the midline of the spinous process) was not sufficient for predicting rotation of a vertebra and can be disregarded during the intraoperative analysis and screw placement.

DOI： 10.1097/BRS.0b013e31815b7e87

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患肢温存を行った高齢者のMFHの1例

中田英二, 時岡孝光, 原田浩史, 杉原進介, 尾崎敏文

中部日本整形外科災害外科学会雑誌 50 ( 6 ) 1119 - 1120 2007年11月

Assessing the range of cervical rotation in patients with rheumatoid arthritis after Atlantoaxial screw fixation using axial CT

Yoshihisa Sugimoto, Masato Tanaka, Kazuo Nakanishi, Haruo Misawa, Tomoyuki Takigawa, Toshifumi Ozaki

SPINE 32 ( 21 ) 2318 - 2321 2007年10月

記述言語：英語出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS

Study Design. Case-series study.
Objective. To assess range of cervical rotation possible after atlantoaxial fixation in rheumatoid arthritis ( RA) patients using axial CT.
Summary of Background Data. The atlantoaxial complex is primarily responsible for rotation, and the percentage of global cervical rotation dependent on C1-C2 is 60%. Fusion of C1-C2 was expected to cause a loss of almost half the normal cervical rotation. However, some authors had reported that cervical rotation in RA patients increased after atlantoaxial fixation because of pain relief. Methods. Nineteen consecutive patients with atlantoaxial instability secondary to RA who had undergone transarticular fixation were included in our study. Visual analog scale was used for assessment of neck pain. We recorded functional CTs to assess C1 to T1 rotation angles before surgery and 6 months after surgery. The patient actively rotated his neck toward right as far as possible, taking care that the shoulders remained in the horizontal plane.
Results. The average visual analog scale for neck pain decreased significantly from 7 ( range, 4-9) before surgery to 3 ( range, 0-5) at 6 months after surgery. The average preoperative C1-T1 rotation angles that were measured using axial CT were 80 in total. C1-T1 rotation angle significantly decreased (55% decrease) after surgery, but there was no difference between right and left motion. Average subaxial rotation (C2-T1) was 31 before surgery and did not increase after surgery.
Conclusion. All 19 patients with RA and atlantoaxial instability in our study had relief of pain and a significant decrease in the C1-T1 rotation angle after atlantoaxial fixation. Subaxial rotation did not change from before to after the operation.

DOI： 10.1097/BRS.0b013e3181557222

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New approach for assessing vascular distribution within bone tumors using dynamic contrast-enhanced MRI

Yukio Kawakami, Toshiyuki Kunisada, Shinsuke Sugihara, Atsushi Ono, Keiichiro Nishida, Nobuhiro Abe, Akira Kawai, Kazuo Fujiwara, Yuki Morimoto, Toshifumi Ozaki

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 133 ( 10 ) 697 - 703 2007年10月

記述言語：英語出版者・発行元：SPRINGER

Purpose To differentiate benign from malignant bone tumors by analyzing the vascular distribution within bone tumors with dynamic contrast-enhanced MRI.
Methods We studied dynamic contrast-enhanced MRI for 49 bone tumors (22 malignant and 27 benign tumors). Seven small regions of interest (ROI) were set inside the largest portion of each tumor. Four ROI were placed evenly on the periphery and three ROI were placed evenly on the line of the longest breadth within the tumor. The slope of the curve (%Slope) was calculated on the time-intensity curves of the whole tumor and of each ROI. The variance values for the %Slope of the ROI were calculated to assess the dispersion of the intensity change at each ROI within the tumor.
Results Mean value of the %Slopes of whole tumor regions for malignant bone tumors (70.4 +/- 60.3%) was significantly higher than that for benign bone tumors (37.6 +/- 52.9%) (P = 0.015), although giant cell tumor (GCT), a locally aggressive tumor, had a relatively higher %Slope. Mean value of the variance of %Slopes for malignant bone tumors (3485.9 +/- 5942.5) was significantly higher than that for all benign tumors (470.4 +/- 583.9) (P = 0.012), indicating that the %Slope values of seven ROI within malignant bone tumors varied more widely compared with the ROI inside benign bone tumors. GCT also demonstrated a lower value.
Conclusion Our method of analyzing the signal intensity change at seven separate regions that evaluates the vascular distribution within a tumor could be a useful tool for differentiating between benign and malignant bone tumors.

DOI： 10.1007/s00432-006-0190-9

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Nontraumatic Subluxation of the Hip after Spine Surgery for Scoliosis in a Patient with Von Recklinghausen’s Disease.

Endo H, Mitani S, Sugihara S, Kuroda T, Nakahara S, Ozaki T

J Orthop Sci 12 ( 5 ) 510 - 514 2007年9月

病的骨折を起こした長管骨転移性骨腫瘍の治療経験

中田英二, 時岡孝光, 黒住健人, 大森貴男, 土井英之, 尾崎敏文

中部日本整形外科災害外科学会雑誌 50 ( 秋季学会 ) 85 - 85 2007年9月

Efficient osteogenic induction of hTERT-immortalized human bone marrow mesenchymal stem cells

Hiroyuki Nakahara, Haruo Misawa, Alejandro Soto-Gutierrez, Jorge David Rivas-Carrillo, Nalu Navarro-Alvarez, Masato Tanaka, Horosuke Endo, Noriaki Tanaka, Toshifumi Ozaki, Naoya Kobayashi

XENOTRANSPLANTATION 14 ( 5 ) 439 - 439 2007年9月

Comparative biomechanical analysis of an improved novel pedicle screw with sheath and bone cement

Tomoyuki Takigawa, Masato Tanaka, Hitoshi Konishi, Hisanori Ikuma, Haruo Misawa, Yoshihisa Sugimoto, Kazuo Nakanishi, Koichi Kuramoto, Keiichiro Nishida, Toshifumi Ozaki

JOURNAL OF SPINAL DISORDERS & TECHNIQUES 20 ( 6 ) 462 - 467 2007年8月

記述言語：英語出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS

Study Design: A human cadaveric biomechanical study of fixation strength of an improved novel pedicle screw (NPS) with cement and a conventional screw.
Objective: To clarify whether the NPS has adequate fixation strength without leakage in vertebrae with low bone quality.
Summary of Background Data: The fixation strength of pedicle screws decreases in frail spines of elderly osteoporotic patients. Augmentation of screw fixation with bone cement must be balanced against increased difficulty of screw removal and risk of cement leakage. We developed the NPS consisting of an internal screw and an outer sheath to mitigate the disadvantages of cement augmentation.
Methods: The T12 and L1 vertebrae obtained from 18 formalin preserved cadavers (11 males and 7 females; mean age, 82.7y) were used. The mean bone mineral density was 0.39 +/- 0.14 g/cm(2). The NPS was inserted into one pedicle of each vertebra and the control screw, a Compact CD2 screw, was inserted into the contralateral pedicle. Both screws were 6 mm in diameter and 40 mm in length. Pull-out tests were performed at a crosshead speed of 10 mm/min. Cyclic loading tests were performed with a maximum 250 N load at 2 Hz until 30,000 cycles.
Results: Cement leakage did not occur in any of the specimens tested. The mean maximum force at pull-out was 760 +/- 344 N for the NPS and 346 172 N for the control screw (P < 0.01). Loosening of 50% of the screws was observed after 17,000 cycles of the NPS and after 30 cycles of the control screw. The hazard ratio of loosening was 19.6 (95% confidence interval 19.3-19.9) (P < 0.001).
Conclusions: The NPS showed a significantly higher mechanical strength than the control screw in both pull-out tests and cyclic loading test than the control screw in both pull-out tests and cyclic loading test. The NPS showed more than adequate strength without cement leakage.

DOI： 10.1097/BSD.0b013e318030d2d6

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脱分化型脂肪肉腫の治療成績 JMOG多施設共同研究

穴澤卯圭, 矢部啓夫, 森岡秀夫, 森井健司, 石井猛, 尾崎敏文, 土屋弘行, 西田佳弘, 保坂泰介

日本整形外科学会雑誌 81 ( 6 ) S747 - S747 2007年6月

2-P1-90 重心動揺検査の結果からみた女子の思春期におけるバランス能力の発達について(姿勢,重心動揺,ポスター,一般演題,実学としてのリハビリテーションの継承と発展,第44回日本リハビリテーション医学会学術集会)

迫間巧将, 千田益生, 堅山佳美, 那須巧, 越智信夫, 尾崎敏文

リハビリテーション医学 : 日本リハビリテーション医学会誌 44 S389 2007年5月

1-P2-9 CTを用いた頚椎手術後の回旋可動域評価(脊髄損傷および脊髄疾患・画像診断,ポスター,一般演題,実学としてのリハビリテーションの継承と発展,第44回日本リハビリテーション医学会学術集会)

杉本佳久, 田中雅人, 中西一夫, 三澤治夫, 瀧川朋亨, 尾崎敏文

リハビリテーション医学 : 日本リハビリテーション医学会誌 44 S292 2007年5月

2-P2-2 人工筋肉を利用した脊髄損傷患者の立ち上がり(脊髄損傷および脊髄疾患・小児,二分脊椎,ポスター,一般演題,実学としてのリハビリテーションの継承と発展,第44回日本リハビリテーション医学会学術集会)

那須巧, 千田益生, 堅山佳美, 長谷川賢也, 迫間巧将, 尾崎敏文, 後藤左知子, 赤澤啓史, 小田浤

リハビリテーション医学 : 日本リハビリテーション医学会誌 44 S400 2007年5月

2A1-I12 低侵襲人工膝関節置換術支援のための工具経路生成法に関する研究(手術支援ロボティクス・メカトロニクス)

源馬文章, 杉田直彦, 光石衛, 阿部信寛, 藤原一夫, 尾崎敏文, 鈴木昌彦, 守屋秀繁, 井上貴之, 藏本孝一, 中島義雄, 谷本圭司

ロボティクス・メカトロニクス講演会講演概要集 2007 "2A1 - I12(1)"-"2A1-I12(2)" 2007年5月

記述言語：日本語出版者・発行元：一般社団法人日本機械学会

Toolpath generation and optimization is considered to be a challenging problem in the minimally invasive orthropedic surgery with a milling robot. The objective of this paper is to minimize the collision of the cutting tool with soft tissues. A novel approach of toolpath generation and optimization is proposed. A redundant axis is implemented to avoid collision with the robot. Some important components are modeled based on the physical requirements. A geometric optimization approach based on the model is proposed to improve the toolpath. Software is developed for this application.

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小児膝蓋骨上極骨折 (upper pole sleeve fracture) の1例

皆川寛, 野田知之, 古松毅之, 那須義久, 尾崎敏文

中部日本整形外科災害外科学会雑誌 50 ( 3 ) 497 - 498 2007年5月

Assessing range of cervical rotation after laminoplasty using axial CT

Yoshihisa Sugimoto, Masato Tanaka, Kazuo Nakanishi, Haruo Misawa, Tomoyuki Takigawa, Hisanori Ikuma, Toshifumi Ozaki

JOURNAL OF SPINAL DISORDERS & TECHNIQUES 20 ( 3 ) 187 - 189 2007年5月

記述言語：英語出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS

Purpose: Although many authors have reported on cervical range of motion, after laminoplasty, they have focused on flexion and extension based on lateral radiographs, not on axial rotation. In this study, we assessed cervical rotation from C1 to T1 after laminoplasty using computed tomography.
Patients and Methods: Eighteen consecutive patients with cervical myelopathy who had undergone laminoplasty were observed. Patient was placed in the supine position on the computed tomography scan table. After the scans in this neutral position were completed, the patient actively rotated his neck as far as possible taking care that the shoulders remained in the horizontal plane. We measured the C1 to T1, C1 to C2, and C2 to T1 rotation angles preoperatively, and at 2 weeks and 6 months after surgery.
Results: The average C1 to T1 rotation angles preoperatively were 46 degrees; on the right and 45 degrees on the left. The percentage of C I to C2 rotation during global cervical rotation (C1 to T1) was 62%. C1 to T1 rotation angle significantly decreased at two weeks after surgery but recovered to almost preoperative levels (11% decreases) by 6 months after surgery with no difference between right and left motion. The average C2 to T1 subaxial rotation angles did not significantly decreased after surgery.
Conclusions: Rotation angle after laminoplasty decreased slightly at 2 weeks after surgery but recovered almost to preoperative levels by 6 months.

DOI： 10.1097/01.bsd.0000211265.58991.2e

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