研究者詳細 - 賴藤　貴志

論文 - 賴藤　貴志

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Cushing’s sign and severe traumatic brain injury in children after blunt trauma: a nationwide retrospective cohort study in Japan 査読

Tetsuya Yumoto, Hiromichi Naito, Takashi Yorifuji, Hiroki Maeyama, Yoshinori Kosaki, Hirotsugu Yamamoto, Kohei Tsukahara, Takaaki Osako, Atsunori Nakao

BMJ Open 8 ( 3 ) e020781 - e020781 2018年3月

掲載種別：研究論文（学術雑誌）出版者・発行元：BMJ

<sec><title>Objective</title>We tested whether Cushing’s sign could predict severe traumatic brain injury (TBI) requiring immediate neurosurgical intervention (BI-NSI) in children after blunt trauma.

</sec><sec><title>Design</title>Retrospective cohort study using Japan Trauma Data Bank.

</sec><sec><title>Setting</title>Emergency and critical care centres in secondary and tertiary hospitals in Japan.

</sec><sec><title>Participants</title>Children between the ages of 2 and 15 years with Glasgow Coma Scale motor scores of 5 or less at presentation after blunt trauma from 2004 to 2015 were included. A total of 1480 paediatric patients were analysed.

</sec><sec><title>Primary outcome measures</title>Patients requiring neurosurgical intervention within 24 hours of hospital arrival and patients who died due to isolated severe TBI were defined as BI-NSI. The combination of systolic blood pressure (SBP) and heart rate (HR) on arrival, which were respectively divided into tertiles, and its correlation with BI-NSI were investigated using a multiple logistic regression model.

</sec><sec><title>Results</title>In the study cohort, 297 (20.1%) exhibited BI-NSI. After adjusting for sex, age category and with or without haemorrhage shock, groups with higher SBP and lower HR (SBP ≥135 mm Hg; HR ≤92 bpm) were significantly associated with BI-NSI (OR 2.84, 95% CI 1.68 to 4.80, P<0.001) compared with the patients with normal vital signs. In age-specific analysis, hypertension and bradycardia were significantly associated with BI-NSI in a group of 7–10 and 11–15 years of age; however, no significant association was observed in a group of 2–6 years of age.

</sec><sec><title>Conclusions</title>Cushing’s sign after blunt trauma was significantly associated with BI-NSI in school-age children and young adolescents.

</sec>

DOI： 10.1136/bmjopen-2017-020781

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Intrauterine and Early Postnatal Exposure to Particulate Air Pollution and Kawasaki Disease: A Nationwide Longitudinal Survey in Japan 査読

Takashi Yorifuji, Hirokazu Tsukahara, Saori Kashima, Hiroyuki Doi

The Journal of Pediatrics 193 147 - 154 2018年2月

Effects of tongue cleaning on Ayurvedic digestive power and oral health-related quality of life: A randomized cross-over study 査読

A. Tokinobu, T. Yorifuji, M. Sasai, H. Doi, T. Tsuda

Complementary Therapies in Medicine 36 9 - 13 2018年2月

Catch-Up Growth and Neurobehavioral Development among Full-Term, Small-for-Gestational-Age Children: A Nationwide Japanese Population-Based Study 査読

Akihito Takeuchi, Takashi Yorifuji, Kazue Nakamura, Kei Tamai, Shigehiro Mori, Makoto Nakamura, Misao Kageyama, Toshihide Kubo, Tatsuya Ogino, Katsuhiro Kobayashi, Hiroyuki Doi

The Journal of Pediatrics 192 41 - 46 2018年1月

Temporal trends of infant and birth outcomes in Minamata after severe methylmercury exposure 査読

Takashi Yorifuji, Saori Kashima, Made Ayu Hitapretiwi Suryadhi, Kawuli Abudureyimu

Environmental Pollution 231 1586 - 1592 2017年12月

Are People With a History of Disease More Susceptible to a Short-term Exposure to Asian Dust? 査読

Saori Kashima, Takashi Yorifuji, Etsuji Suzuki

Epidemiology 28 S60 - S66 2017年10月

Impact of maternal and paternal smoking on birth outcomes 査読

Sachiko Inoue, Hiroo Naruse, Takashi Yorifuji, Tsuguhiko Kato, Takeshi Murakoshi, Hiroyuki Doi, S.V. Subramanian

Journal of Public Health 39 ( 3 ) 557 - 566 2017年9月

Is there an obesity paradox in the Japanese elderly population? A community-based cohort study of 13 280 men and women 査読

Kenji Yamazaki, Etsuji Suzuki, Takashi Yorifuji, Toshihide Tsuda, Toshiki Ohta, Kazuko Ishikawa-Takata, Hiroyuki Doi

GERIATRICS & GERONTOLOGY INTERNATIONAL 17 ( 9 ) 1257 - 1264 2017年9月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：WILEY

AimDespite increased interest in an obesity paradox (i.e. a survival advantage of being obese), evidence remains sparse in Japanese populations. We aimed to verify this phenomenon among community-dwelling older adults in Japan.
MethodsOlder adults aged 65-84 years randomly chosen from all 74 municipalities in Shizuoka Prefecture completed questionnaires including body mass index information. Participants were followed from 1999 to 2009. Following World Health Organization guidelines, participants were classified using an appropriate body mass index for Asian populations as follows: <18.5 kg/m(2) (underweight), 18.5-23.0 kg/m(2) (normal weight), 23.0-27.5 kg/m(2) (overweight) and 27.5 kg/m(2) (obesity). We estimated hazard ratios and their 95% confidence intervals for all-cause mortality, controlling for sex, age, smoking status, alcohol consumption, physical activity, hypertension and diabetes mellitus.
ResultsCompared with normal-weight participants, overweight/obese participants tended to have lower hazard ratios; the multivariate hazard ratios (95% confidence interval) were 0.86 (0.62-1.19) for obesity, 0.83 (0.73-0.94) for overweight and 1.60 (1.40-1.82) for underweight. In subgroup analyses by sex and age, the hazard ratios tended to be lower among obese men, albeit not significantly; hazard ratios (95% confidence interval) were 0.56 (0.25-1.27) in men aged 65-74 years, and 0.78 (0.41-1.45) in men aged 75-84 years.
ConclusionsThe present study provides evidence of a conservative obesity paradox among older Japanese people, using the appropriate body mass index cut-off points for Asian populations. In particular, obese older men tend to have a lower risk of all-cause mortality. Geriatr Gerontol Int 2017; 17: 1257-1264.

DOI： 10.1111/ggi.12851

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PubMed

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New age-based weight estimation formulae for Japanese children 査読

Nobuyuki Nosaka, Takashi Yorifuji, Emily Knaup, Kohei Tsukahara, Takashi Muguruma, Ayumi Okada, Hirokazu Tsukahara, Hiroyuki Doi

Pediatrics International 59 ( 6 ) 727 - 732 2017年6月

Height and blood chemistry in adults with a history of developmental arsenic poisoning from contaminated milk powder 査読

Takashi Yorifuji, Kenichi Matsuoka, Philippe Grandjean

Environmental Research 155 86 - 91 2017年5月

Association of maternal age with child health: A Japanese longitudinal study 査読

Tsuguhiko Kato, Takashi Yorifuji, Michiyo Yamakawa, Sachiko Inoue, Hiroyuki Doi, Akira Eboshida, Ichiro Kawachi

PLOS ONE 12 ( 2 ) e0172544 - e0172544 2017年2月

Prenatal exposure to outdoor air pollution and child behavioral problems at school age in Japan 査読

Takashi Yorifuji, Saori Kashima, Midory Higa Diez, Yoko Kado, Satoshi Sanada, Hiroyuki Doi

Environment International 99 192 - 198 2017年2月

Behavioral outcomes of school-aged full-term small-for-gestational-age infants: A nationwide Japanese population-based study 査読

Akihito Takeuchi, Takashi Yorifuji, Kyohei Takahashi, Makoto Nakamura, Misao Kageyama, Toshihide Kubo, Tatsuya Ogino, Katsuhiro Kobayashi, Hiroyuki Doi

Brain and Development 39 ( 2 ) 101 - 106 2017年2月

Maternal smoking location at home and hospitalization for respiratory tract infections among children in Japan 査読

Michiyo Yamakawa, Takashi Yorifuji, Tsuguhiko Kato, Toshihide Tsuda, Hiroyuki Doi

ARCHIVES OF ENVIRONMENTAL & OCCUPATIONAL HEALTH 72 ( 6 ) 343 - 350 2017年

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD

We examined the effects of maternal smoking location at home on hospitalization for respiratory tract infections among young children in Japan. We used the large nationwide population-based longitudinal survey and restricted study participants to children born after 37 gestational weeks and singleton births (n = 43,851). We evaluated the associations among children between the ages of 6 and 18months and between the ages of 18 and 30months, respectively. After adjusting for potential confounders, both maternal outdoor and indoor smoking were associated with the elevated risk. The adjusted odds ratios (95% confidence intervals) of maternal outdoor and indoor smoking (vs nonsmoking mothers) were 1.21 (1.01-1.44) and 1.18 (1.04-1.33), respectively, in children between the ages of 6 and 18months. We thus encourage a smoke-free home policy to protect children from second- and third-hand smoke exposure.

DOI： 10.1080/19338244.2016.1255582

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Fine-particulate Air Pollution from Diesel Emission Control and Mortality Rates in Tokyo A Quasi-experimental Study 査読

Takashi Yorifuji, Saori Kashima, Hiroyuki Doi

EPIDEMIOLOGY 27 ( 6 ) 769 - 778 2016年11月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS

Background: Evidence linking air pollution with adverse health outcomes is accumulating. However, few studies have adopted a quasi-experimental design to evaluate whether decline in air pollution from regulatory action improves public health. We evaluated the effect of a diesel emission control ordinance introduced in 2003 on mortality rates in 23 wards of the Tokyo metropolitan area, Japan, from October 2000 to September 2012, taking into account change in mortality rates in a reference population (Osaka) with a introduction of such a regulation in 2009.
Methods: We obtained daily counts of all-cause and cause-specific mortality and concentrations of nitrogen dioxide (NO2) and particulate matter less than 2.5 mu m in diameter (PM2.5) during the study period. We employed interrupted time-series analysis to analyze the data.
Results: Decline in NO2 during the study period was similar in the two areas, while decline in PM2.5 and the improvement in age-standardized mortality rates were greater in Tokyo's 23 wards compared with Osaka. Even after adjusting for age-standardized mortality rates in Osaka, percent changes in mortality between the first 3-year interval (October 2000 to September 2003) and the last 3-year interval (October 2009 to September 2012) were -6.0% for all causes, -11% for cardiovascular disease, -10% for ischemic heart disease, -6.2% for cerebrovascular disease, -22% for pulmonary disease, and -4.9% for lung cancer. We did not observe a decline in mortality from other causes.
Conclusions: This quasi-experimental study in Tokyo suggests that emission control was associated with improvements in both air quality and health outcomes.

DOI： 10.1097/EDE.0000000000000546

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Children's Media Use and Self-Regulation Behavior: Longitudinal Associations in a Nationwide Japanese Study 査読

Sachiko Inoue, Takashi Yorifuji, Tsuguhiko Kato, Satoshi Sanada, Hiroyuki Doi, Ichiro Kawachi

MATERNAL AND CHILD HEALTH JOURNAL 20 ( 10 ) 2084 - 2099 2016年10月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：SPRINGER/PLENUM PUBLISHERS

Objective The effect of media use on child behavior has long been a concern. Although studies have shown robust cross-sectional relations between TV viewing and child behavior, longitudinal studies remain scarce. Methods We analyzed the Longitudinal Survey of Babies, conducted by Japan's Ministry of Health, Labour and Welfare since 2001. Among 53,575 families, 47,010 responded to the baseline survey; they were followed up every year for 8 years. Complete data were available for longitudinal analysis among 32,439 participants. Daily media use (TV viewing and video game-playing hours at ages 3, 4, and 5 years) was used as the main exposure. We employed an index of the children's self-regulatory behavior as the outcome variable. Odds ratios and 95 % confidence intervals (CIs) were estimated. Results Among boys, longer TV-viewing times at ages 4 and 5 were related to problematic self-regulatory behavior. Compared with boys who watched just 1-2 h of TV a day, those who watched it 4-5 h had a 1.79-fold greater risk (CI 1.22-2.64) of problematic self-regulatory behavior, according to parental report. Among girls, similar results were evident at ages 4 and 5 (e.g., adjusted odds ratios for 4-5 h daily viewing versus 1-2 h at age 4: 2.59; 95 % CI 1.59-4.22). Video games may have a protective effect on the risk of problematic self-regulatory behavior at ages 3 and 5. Conclusion Longer daily exposure to TV during early childhood (age 4-5) may be associated with subsequent problematic child self-regulatory behavior.

DOI： 10.1007/s10995-016-2031-z

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PubMed

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Development of a Japanese scale for assessment of paediatric normal weight 査読

Nobuyuki Nosaka, Takashi Yorifuji, Emily Knaup, Takashi Muguruma, Ayumi Okada, Hirokazu Tsukahara, Hiroyuki Doi

RESUSCITATION 105 E12 2016年8月

Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA) 査読

Christopher J. Portier, Bruce K. Armstrong, Bruce C. Baguley, Xaver Baur, Igor Belyaev, Robert Belle, Fiorella Belpoggi, Annibale Biggeri, Maarten C. Bosland, Paolo Bruzzi, Lygia Therese Budnik, Merete D. Bugge, Kathleen Burns, Gloria M. Calaf, David O. Carpenter, Hillary M. Carpenter, Lizbeth Lopez-Carrillo, Richard Clapp, Pierluigi Cocco, Dario Consonni, Pietro Comba, Elena Craft, Mohamed Aqiel Dalvie, Devra Davis, Paul A. Demers, Anneclaire J. De Roos, Jamie DeWitt, Francesco Forastiere, Jonathan H. Freedman, Lin Fritschi, Caroline Gaus, Julia M. Gohlke, Marcel Goldberg, Eberhard Greiser, Johnni Hansen, Lennart Hardell, Michael Hauptmann, Wei Huang, James Huff, Margaret O. James, C. W. Jameson, Andreas Kortenkamp, Annette Kopp-Schneider, Hans Kromhout, Marcelo L. Larramendy, Philip J. Landrigan, Lawrence H. Lash, Dariusz Leszczynski, Charles F. Lynch, Corrado Magnani, Daniele Mandrioli, Francis L. Martin, Enzo Merler, Paola Michelozzi, Lucia Miligi, Anthony B. Miller, Dario Mirabelli, Franklin E. Mirer, Saloshni Naidoo, Melissa J. Perry, Maria Grazia Petronio, Roberta Pirastu, Ralph J. Portier, Kenneth S. Ramos, Larry W. Robertson, Theresa Rodriguez, Martin Roosli, Matt K. Ross, Deodutta Roy, Ivan Rusyn, Paulo Saldiva, Jennifer Sass, Kai Savolainen, Paul T. J. Scheepers, Consolato Sergi, Ellen K. Silbergeld, Martyn T. Smith, Bernard W. Stewart, Patrice Sutton, Fabio Tateo, Benedetto Terracini, Heinz W. Thielmann, David B. Thomas, Harri Vainio, John E. Vena, Paolo Vineis, Elisabete Weiderpass, Dennis D. Weisenburger, Tracey J. Woodruff, Takashi Yorifuji, Il Je Yu, Paola Zambon, Hajo Zeeb, Shu-Feng Zhou

JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH 70 ( 8 ) 741 - 745 2016年8月

Breastfeeding and Risk of Kawasaki Disease: A Nationwide Longitudinal Survey in Japan 査読

Takashi Yorifuji, Hirokazu Tsukahara, Hiroyuki Doi

PEDIATRICS 137 ( 6 ) 2016年6月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：AMER ACAD PEDIATRICS

BACKGROUND AND OBJECTIVES: Kawasaki disease (KD) is the most common cause of childhood-acquired heart disease in developed countries. However, the etiology of KD is not known. Aberrant immune responses are considered to play key roles in disease initiation and breastfeeding can mature immune system in infants. We thus examined the association between breastfeeding and the development of KD.
METHODS: We used a nationwide population-based longitudinal survey ongoing since 2010 and restricted participants to a total of 37630 children who had data on their feeding during infancy. Infant feeding practice was queried at 6 to 7 months of age, and responses to questions about hospital admission for KD during the period from 6 to 30 months of age were used as outcome. We conducted logistic regression analyses controlling for child and maternal factors with formula feeding without colostrum as our reference group.
RESULTS: A total of 232 hospital admissions were observed. Children who were breastfed exclusively or partially were less likely to be hospitalized for KD compared with those who were formula fed without colostrum; odds ratios for hospitalization were 0.26 (95% confidence interval: 0.12-0.55) for exclusive breastfeeding and 0.27 (95% confidence interval: 0.13-0.55) for partial breastfeeding. Although the risk reduction was not statistically significant, feeding colostrum only also provided a protective effect.
CONCLUSIONS: We observed protective effects of breastfeeding on the development of KD during the period from 6 to 30 months of age in a nationwide, population-based, longitudinal survey in Japan, the country in which KD is most common.

DOI： 10.1542/peds.2015-3919

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Neurodevelopment in full-term small for gestational age infants: A nationwide Japanese population-based study 査読

Akihito Takeuchi, Takashi Yorifuji, Kyohei Takahashi, Makoto Nakamura, Misao Kageyama, Toshihide Kubo, Tatsuya Ogino, Hiroyuki Doi

BRAIN & DEVELOPMENT 38 ( 6 ) 529 - 537 2016年6月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：ELSEVIER SCIENCE BV

Objective: To investigate neurological development in small for gestational age (SGA) infants, with a focus on full-term SGA infants.
Methods: We analyzed data from a large, Japanese, nationwide, population-based longitudinal survey started in 2001. We restricted the study to participants born before 42 weeks of gestation (n = 46,563). Parents were asked questions about motor and language development when the children were 2.5 years old, and about behavioral development at 5.5 years. We analyzed the relationships between SGA status and development by logistic regression. Odds ratios (ORs) and 95% confidence intervals (95% CI) were calculated for each outcome for full-term and preterm births, adjusting for potential infant- and parent-related confounding factors. We also calculated the population-attributable fractions to estimate the public impact of SGA births.
Results: SGA full-term children were more likely to demonstrate developmental delays at 2.5 years, e.g., being unable to walk alone (OR 3.0, 95% CI: 1.7, 5.3), compose a two-phrase sentence (OR 1.5, 95% CI: 1.2, 1.8), or use a spoon to eat (OR 1.5, 95% CI: 1.1, 1.9). SGA status also had some degree of negative impacts on behavioral problems at 5.5 years among term children, e.g., being unable to listen without fidgeting (OR 1.2, 95% CI: 1.1, 1.3), or remain patient (OR 1.1, 95% CI: 1.0, 1.2). The public health impacts were comparable between full-term and preterm SGA children at 2.5 years.
Conclusion: SGA is a risk factor for developmental delay, even in full-term infants, with non-negligible public health impacts. (c) 2016 published by Elsevier B.V. on behalf of The Japanese Society of Child Neurology.

DOI： 10.1016/j.braindev.2015.12.013

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論文 - 賴藤 貴志

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論文 - 賴藤　貴志