研究者詳細 - 賴藤　貴志

論文 - 賴藤　貴志

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Causal Effect of the Tokyo 2020 Olympic and Paralympic Games on the Number of COVID-19 Cases under COVID-19 Pandemic: An Ecological Study Using the Synthetic Control Method 査読

Norio Yamamoto, Toshiharu Mitsuhashi, Yuuki Tsuchihashi, Takashi Yorifuji

Journal of Personalized Medicine 12 ( 2 ) 209 - 209 2022年2月

担当区分：最終著者記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：MDPI AG

Previous studies have not assessed the causal effect of the Olympic Games on the spread of pandemics. Using the synthetic control method and the national public city data in Japan recorded from February to September 2021, we estimated the causal effects of the Tokyo 2020 Olympic and Paralympic Games on the number of coronavirus disease 2019 (COVID-19) cases. The difference between the number of COVID-19 cases in Tokyo and a counterfactual “synthetic Tokyo” (created using synthetic control method) after the opening of the Tokyo 2020 Games (23 July 2021) widened gradually and then considerably over time. It was predicted that the Tokyo 2020 Games increased the number of COVID-19 cases in Tokyo by approximately 469.4 per 100,000 population from the opening of the event to 30 September. However, sensitivity analysis of the ratio of the pre- and post-game root mean square prediction errors using regression weights did not suggest robustness. Our results showed that the Tokyo 2020 Games probably increased the number of COVID-19 cases even under preventive regulations; however, the extent of this increase was difficult to estimate clearly due to an overlap with the fifth wave associated with the Delta variant.

DOI： 10.3390/jpm12020209

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Questionnaire Survey on COVID-19 Vaccination at Okayama University in Japan: Factors Promoting Vaccination Among Young Adults 査読

Chigusa Higuchi, Naomi Matsumoto, Yoshiaki Iwasaki, Takashi Yorifuji, Junichiro Yamazaki, Yasutomo Nasu, Hirofumi Makino

Journal of Disaster Research 17 ( 1 ) 21 - 30 2022年1月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Fuji Technology Press Ltd.

COVID-19 has been prevalent worldwide since 2019. Increasing COVID-19 vaccination coverage is an important measure to combat the disease. An online survey was conducted with university students and personnel who were vaccinated against COVID-19 at a mass vaccination event to examine the factors promoting vaccination among young adults. The online survey was conducted with persons vaccinated at Okayama University from June 5 to September 27, 2021. Although the number of those who had fever >37.5°C increased after the second vaccination compared to the first, the vaccinated persons got more satisfied after the second shot.

DOI： 10.20965/jdr.2022.p0021

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Reusable Medical Isolation Gowns with a Liquid Barrier: Washing Gowns in the Coronavirus Disease 2019 Pandemic Era? 査読

Naito H, Tsukahara K, Takao S, Yorifuji T, Nakao A

JMA Journal 5 ( 1 ) 107 - 108 2022年1月

Association of nighttime sleep with behaviors in Japanese early childhood. 査読国際誌

Yusuke Yamauchi, Soshi Takao, Naomi Matsumoto, Takashi Yorifuji

Pediatrics international : official journal of the Japan Pediatric Society 64 ( 1 ) e15354 - e15354 2022年1月

担当区分：最終著者記述言語：英語掲載種別：研究論文（学術雑誌）

BACKGROUND: Preschool children in Asian countries, including Japan, sleep for a shorter duration at night than those in Europe and the USA. We examined the effects of the nighttime sleep duration on behavioral development in early childhood in Japan. METHODS: We used data from a large Japanese nationwide, population-based, longitudinal survey that began in 2001. We restricted the study participants to children born after 37 gestational weeks, with a birth weight ≥ 2500 g and singleton births (n = 41 890). The nighttime sleep duration was examined at 2.5 years old. Responses to survey questions regarding age-appropriate behavior at 5.5 years old were used as indicators of behavioral development. We conducted logistic regression analyses with adjustment for confounding factors, with ≥11 h of nighttime sleep as the reference group. RESULTS: The odds ratios for children who had ≤9 h of nighttime sleep, which was associated with being unable to listen with fidgeting and being unable to remain patient, were 1.26 (95% confidence interval, 1.14-1.39) and 1.27 (1.16-1.38), respectively. Children who had an irregular nighttime sleep duration were associated with age-appropriate behavioral inabilities. These results were similar in children who usually and sometimes took naps to those before stratification by the frequency of napping. CONCLUSION: A short nighttime sleep duration especially affects hyperactivity and impulsivity. An irregular nighttime sleep duration increases the inability to perform overall age-appropriate behaviors more than a short sleep duration. Ensuring a regular and sufficient nighttime sleep duration in early childhood is important for healthy behavioral development.

DOI： 10.1111/ped.15354

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Associations between Early Surgery and Postoperative Outcomes in Elderly Patients with Distal Femur Fracture: A Retrospective Cohort Study. 査読

Yamamoto N, Ohbe H, Tomita Y, Yorifuji T, Nakajima M, Sasabuchi Y, Miyamoto Y, Matsui H, Noda T, Yasunaga H

J Clin Med. 10 ( 24 ) 5800 - 5800 2021年12月

Alcohol Consumption and Age-related Macular Degeneration: A Systematic Review and Dose-response Meta-analysis. 査読国際誌

Jingjing Zhang, Toshiharu Mitsuhashi, Toshihiko Matsuo, Takashi Yorifuji, Jun Hamada, Yangyang Liu

Current eye research 46 ( 12 ) 1900 - 1907 2021年12月

記述言語：英語掲載種別：研究論文（学術雑誌）

Purpose: To perform a systematic review on the association between alcohol consumption and risk of age-related macular degeneration (AMD) using a meta-analytical approach.Method: Systematic literature research was conducted according to the Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines. Both categorical and dose-response meta-analysis was performed separately for early and late AMD. A fixed-effect model was used to calculate pooled effect estimates with 95% confidence interval (CI).Result: Seven studies were included in the analysis with 4,566 and 440 cases of early and late AMD, respectively. Compared to the nondrinkers or occasional drinkers, the pooled effect estimates for early AMD with moderate (1.19, 95% CI [1.03-1.37]) and heavy (1.24, [1.10-1.39]) alcohol consumption, but not light (0.95, [0.90-1.06]) alcohol consumption, were statistically significant. However, the pooled effect estimates for late AMD with light (1.03, [0.79-1.33]), moderate (1.13, [0.83-1.55]), and heavy (0.98, [0.63-1.53]) alcohol consumption were found to be insignificant. A linear dose-response relationship was established (P < .05) between alcohol consumption and risk of early AMD, and the pooled effect estimate for an increase in alcohol consumption of 10 g/day was 1.14 (1.08-1.21).Conclusion: Moderate and heavy alcohol consumption could increase the risk of early AMD, but not late AMD, with a linear dose-response relationship.

DOI： 10.1080/02713683.2021.1942070

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Trajectory of body mass index and height changes from childhood to adolescence: a nationwide birth cohort in Japan. 査読国際誌

Naomi Matsumoto, Toshihide Kubo, Kazue Nakamura, Toshiharu Mitsuhashi, Akihito Takeuchi, Hirokazu Tsukahara, Takashi Yorifuji

Scientific reports 11 ( 1 ) 23004 - 23004 2021年11月

担当区分：最終著者記述言語：英語掲載種別：研究論文（学術雑誌）

To investigate the dynamics of body mass index (BMI) and height changes in childhood leading to obesity in adolescents. BMI Z-scores were calculated using the LMS (lambda-mu-sigma) method based on yearly height and weight information (age 1.5-15 years) from a nationwide Japanese birth cohort that started in 2001 (n = 26,711). We delineated the trajectories of BMI and height changes leading to obesity at age 15 years using mixed effect models. Children who became obese at the age of 15 years kept relatively high BMI z-scores through childhood for both genders, and had an increasing trend over time as opposed to the normal weight group, with an increasing slope during puberty. Early adiposity rebound was associated with overweight or obesity at the age of 15 years. Age at peak height velocity (APHV) occurred earlier in the obese/overweight group at age 15 years than in the normal weight group, and occurred later in the underweight group. Obese adolescents experienced early adiposity rebound timing and maintained a serial BMI z-score increase throughout childhood, with a greater slope at puberty. An earlier peak in height gain during puberty may have contributed to the observed patterns of BMI change.

DOI： 10.1038/s41598-021-02464-z

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Current Insights into Atopic March. 査読国際誌

Mitsuru Tsuge, Masanori Ikeda, Naomi Matsumoto, Takashi Yorifuji, Hirokazu Tsukahara

Children (Basel, Switzerland) 8 ( 11 ) 1067 - 1067 2021年11月

記述言語：英語掲載種別：研究論文（学術雑誌）

The incidence of allergic diseases is increasing, and research on their epidemiology, pathophysiology, and the prevention of onset is urgently needed. The onset of allergic disease begins in infancy with atopic dermatitis and food allergy and develops into allergic asthma and allergic rhinitis in childhood; the process is defined as "atopic march". Atopic march is caused by multiple immunological pathways, including allergen exposure, environmental pollutants, skin barrier dysfunction, type 2 inflammation, and oxidative stress, which promote the progression of atopic march. Using recent evidence, herein, we explain the involvement of allergic inflammatory conditions and oxidative stress in the process of atopic march, its epidemiology, and methods for prevention of onset.

DOI： 10.3390/children8111067

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Association between Dental Caries and Influenza Infection in Children: A Japanese Nationwide Population-Based Study. 査読

Matsumoto N, Kadowaki T, Tsukahara H, Yorifuji T

Children (Basel). 8 ( 9 ) 780 - 780 2021年9月

Short or Irregular Sleep Duration in Early Childhood Increases Risk of Injury for Primary School-Age Children: A Nationwide Longitudinal Birth Cohort in Japan. 査読

Obara T, Naito H, Tsukahara K, Matsumoto N, Yamamoto H, Yorifuji T, Nakao A

Int J Environ Res Public Health. 18 ( 18 ) 9512 - 9512 2021年9月

Emergency dispatches for suicide attempts during the COVID-19 outbreak in Okayama, Japan: A descriptive epidemiological study 査読

Habu H, Takao S, Fujimoto R, Naito H, Nakao A, Yorifuji T

J Epidemiol. 31 ( 9 ) 511 - 517 2021年9月

Association between Emergency Medical Services Transport Time and Survival in Patients with Traumatic Cardiac Arrest: A Nationwide Retrospective Observational Study 査読

Naito H, Yumoto T, Yorifuji T, Nojima T, Yamamoto H, Yamada T, Tsukahara K, Inaba M, Nishimura T, Uehara T, Nakao A

BMC Emerg Med. 21 ( 1 ) 104 - 104 2021年9月

Early childhood exposure to maternal smoking and behavioral development. 査読国際誌

Makiko Ariyoshi, Toshiharu Mitsuhashi, Naomi Matsumoto, Kazue Nakamura, Takashi Yorifuji

Archives of environmental & occupational health 77 ( 7 ) 568 - 575 2021年8月

担当区分：最終著者記述言語：英語掲載種別：研究論文（学術雑誌）

We examined the association between early childhood exposure to maternal smoking and behavioral issues at 8 years old using a large nationwide population-based longitudinal survey in Japan that began in 2001. We included 46,737 children with information about maternal smoking taken from the 6-month survey. We used logistic regression analysis to examine the hypothesis. Early childhood exposure to maternal smoking increased the risk of behavioral problems related to attention and aggressive or disruptive behavior. The adjusted odds ratios (95% confidence intervals) were 1.37 (1.22-1.54) for inability to wait their turn during play and 1.40 (1.27-1.55) for destroying toys and, compared with children of nonsmoking mothers. Children of mothers who were heavy smokers were more likely to develop behavioral problems than others. Stopping early childhood exposure to maternal exposure can protect children's neurodevelopment.

DOI： 10.1080/19338244.2021.1972278

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Effect of Patient Clinical Variables in Osteoporosis Classification Using Hip X-rays in Deep Learning Analysis. 査読

Yamamoto N, Sukegawa S, Yamashita K, Manabe M, Nakano K, Takabatake K, Kawai H, Ozaki T, Kawasaki K, Nagatsuka H, Furuki Y, Yorifuji T

Medicina (Kaunas). 57 ( 8 ) 846 - 846 2021年8月

Television-watching in the early years of life and the association with parents' concerns about decreased visual acuity in their elementary school-aged child: results of a nationwide population-based longitudinal survey of Japan 査読

Matsuo T, Yorifuji T

Jpn J Ophthalmol. 65 ( 4 ) 561 - 568 2021年7月

Excess all-cause mortality during the COVID-19 outbreak in Japan. 査読

Yorifuji T, Matsumoto N, Takao S

J Epidemiol. 31 ( 1 ) 90 - 92 2021年1月

Environmental factors associated with expression of symptoms in children with autism 査読

Yoko Kado, Shigeru Oono, Takashi Yorifuji, Aki Mizumoto, Satoshi Sanada

HNUE Journal of Science, Educational Science 66 ( 4AB ) 3 - 10 2021年

Intubation during a medevac flight: safety and effect on total prehospital time in the helicopter emergency medical service system 査読

Hiroki Maeyama, Hiromichi Naito, Francis X. Guyette, Takashi Yorifuji, Yuki Banshotani, Daisaku Matsui, Tetsuya Yumoto, Atsunori Nakao, Makoto Kobayashi

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 28 ( 1 ) 89 2020年12月

掲載種別：研究論文（学術雑誌）出版者・発行元：Springer Science and Business Media LLC

<title>Abstract</title>
<sec>
<title>Introduction</title>
The Helicopter Emergency Medical Service (HEMS) commonly intubates patients who require advanced airway support prior to takeoff. In-flight intubation (IFI) is avoided because it is considered difficult due to limited space, difficulty communicating, and vibration in flight. However, IFI may shorten the total prehospital time. We tested whether IFI can be performed safely by the HEMS.

</sec>
<sec>
<title>Methods</title>
We conducted a retrospective cohort study in adult patients transported from 2010 to 2017 who received prehospital, non-emergent intubation from a single HEMS. We divided the cohort in two groups, patients intubated during flight (flight group, FG) and patients intubated before takeoff (ground group, GG). The primary outcome was the proportion of successful intubations. Secondary outcomes included total prehospital time and the incidence of complications.

</sec>
<sec>
<title>Results</title>
We analyzed 376 patients transported during the study period, 192 patients in the FG and 184 patients in the GG. The intubation success rate did not differ between the two groups (FG 189/192 [98.4%] vs. GG 179/184 [97.3%], <italic>p</italic> = 0.50). There were also no differences in hypoxia (FG 4/117 [3.4%] vs. GG 4/95 [4.2%], <italic>p</italic> = 1.00) or hypotension (FG 6/117 [5.1%] vs. GG 5/95 [5.3%], <italic>p</italic> = 1.00) between the two groups. Scene time and total prehospital time were shorter in the FG (scene time 7 min vs. 14 min, <italic>p</italic> < 0.001; total prehospital time 33.5 min vs. 40.0 min, <italic>p</italic> < 0.001).

</sec>
<sec>
<title>Conclusions</title>
IFI was safely performed with high success rates, similar to intubation on the ground, without increasing the risk of hypoxia or hypotension. IFI by experienced providers shortened transportation time, which may improve patient outcomes.

</sec>

DOI： 10.1186/s13049-020-00784-z

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その他リンク： http://link.springer.com/article/10.1186/s13049-020-00784-z/fulltext.html

Antenatal Care Visits and Adverse Pregnancy Outcomes at a Hospital in Rural Western Province, Rwanda 査読

Akintije CS, Yorifuji T, Wada T, Mukakarake MG, Mutesa L, Yamamoto T

Acta Med Okayama. 74 ( 6 ) 495 - 503 2020年12月

Delay in Emergency Medical Service Transportation Responsiveness during the COVID-19 Pandemic in a Minimally Affected Region 査読

Ageta K, Naito H, Yorifuji T, Obara T, Nojima T, Yamada T, Tsukahara K, Yakushiji H, Nakao A

Acta Med Okayama. 74 ( 6 ) 513 - 520 2020年12月

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