Faculty Profiles - NISHIDA Keiichiro

Papers - NISHIDA Keiichiro

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Total Hip Arthroplasty Without Blood Transfusion in a Jehovah's Witness : A Case Report

Tanaka Takaaki, Okada Yoshiki, Ozaki Toshifumi, Fujiwara Kazuo, Endo Hirosuke, Nishida Keiichiro

The Journal of the Chugoku-Shikoku Orthopaedic Association 26 ( 2 ) 255 - 259 2014

Language：Japanese Publisher：The Chugoku-Shikoku Orthopaedic Association

Jehovah's Witnesses refuse blood transfusions on the basis of their religious belief. We report our experience with total hip arthroplasty without blood transfusion in a Jehovah's Witness.<br>The patient was a 70-year-old woman who had been receiving treatment for rheumatoid arthritis for 34 year and had been taking anti-platelet agents for atrial fibrillation and hypertension. Plain radiographs revealed severe erosions (Larsen Grade 4) in the right hip. We used a cemented femoral component and reamed the acetabulum gently to minimize any bleeding, while performing intraoperative blood-salvaging autotransfusion.<br>We carried out hybrid total hip arthroplasty with a cementless acetabular component and a cemented femoral component. The operation time was 62 minutes, intraoperative blood loss was 50ml, and postoperative blood loss was 90ml. The preoperative hemoglobin level was 9.9g/dl, and the lowest hemoglobin level was 6.8g/dl after surgery. At the final follow-up, the patient was able to walk with a T-shaped walking stick, and her Japanese Orthopaedics Association score (right/left) was 80 points/81 points on.<br>We considered that the use of a cemented femoral component and gentle reaming of the acetabulum were factors that reduced bleeding during total hip arthroplasty.

DOI： 10.11360/jcsoa.26.255

CiNii Article

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Waddington's epigenetic landscape and etiology of rheumatoid arthritis

Nishida Keiichiro

Clinical Rheumatology and Related Research 26 ( 1 ) 5 - 8 2014

Light and electron microscopic detection of inflammation-targeting liposomes encapsulating high-density colloidal gold in arthritic mice.

Maehara A, Nishida K, Furutani M, Matsumoto E, Ohtsuka A, Ninomiya Y, Oohashi T

Inflamm Res. 63 ( 2 ) 139 - 147 2014

SH3BP2 gain-of-function mutation exacerbates inflammation and bone loss in a murine collagen-induced arthritis model

Mukai, T., Gallant, R., Ishida, S., Yoshitaka, T., Kittaka, M., Nishida, K., Fox, D.A., Morita, Y., Ueki, Y.

PLoS ONE 9 ( 8 ) 2014

Development and validation of a new radiographic scoring system to evaluate bone and cartilage destruction and healing of large joints with rheumatoid arthritis: ARASHI (Assessment of rheumatoid arthritis by scoring of large joint destruction and healing in radiographic imaging) study. International journal

Atsushi Kaneko, Isao Matsushita, Katsuaki Kanbe, Katsumitsu Arai, Yoshiaki Kuga, Asami Abe, Takeshi Matsumoto, Natsuko Nakagawa, Keiichiro Nishida

Modern rheumatology 23 ( 6 ) 1053 - 62 2013.11

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: To assess the reliability and sensitivity of a novel scoring method to evaluate the radiographic appearance of and longitudinal changes including joint remodeling in large joints with early and established rheumatoid arthritis (RA). METHODS: The ARASHI study group devised new radiographic scoring systems (Status score; range 0-16 points, and Change score; range -11 to 12 points) for evaluation of large joints with RA. Radiographs showing anterior/posterior views of large joints (shoulder, elbow, hip, knee, and ankle joints) taken at two time points (mean interval 2.3 years) were collected from 25 patients with established RA (5 patients for each of the 5 joints, 50 films in total), and an additional 5 films of each joint with severe joint destruction were collected from 5 different sets of RA patients. After consensus on the definition of each component and reader training, images were evaluated using the Larsen's grading system and the ARASHI Status and Change score by 9 independent senior orthopedic surgeons. The reliability was estimated by intra-class correlation coefficients (ICCs) and measurement error by 95% confidence intervals of minimum detectable change (MDC95). RESULTS: ARASHI Status score and Change score significantly correlated with Larsen's grade (r = 0.89, P < 0.0001) and follow-up-baseline differences in Larsen's grade (r = 0.83, P < 0.0001), respectively. Inter-reader ICCs were very high for both Status score (0.88, 95% confidence interval [CI], 0.83-0.92, P < 0.001) and Change score (0.92, 95% CI, 0.87-0.96, P < 0.001). Intra-reader ICCs were also very high for both Status score (0.92, 95% CI, 0.71-0.98, P < 0.001) and Change score (0.97, 95% CI, 0.91-0.99, P < 0.001). The MDC95 for inter-reader agreement were 4.18 (25% of maximum obtainable score, MOS) and 4.99 (21% of MOS) for Status score and Change score, respectively. The MDC95 for intra-reader agreement was acceptable with 2.82 (17% of MOS) and 3.02 (13% of MOS) for Status score and Change score, respectively. CONCLUSION: The ARASHI scoring method showed good inter-/intra-reader reliability with high ICCs and acceptable MDC95 with respect to each large joint and the components of both Status and Change scores. The results suggest that the ARASHI scoring method might be useful for the assessment of status, as well as longitudinal monitoring of destruction and remodeling of large joints with RA.

DOI： 10.1007/s10165-012-0823-6

PubMed

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Occult Compression Fracture of Metacarpal Head without Evidence of Avascular Necrosis Reviewed

Keiichiro Nishida, Hiroyuki Hashizume, Akihiro Matsukawa, Kenzo Hashizume, Yasunori Shimamura, Yasuyaki Torigoe, Toshifumi Ozaki

ACTA MEDICA OKAYAMA 67 ( 5 ) 311 - 317 2013.10

Language：English Publishing type：Research paper (scientific journal) Publisher：OKAYAMA UNIV MED SCHOOL

We report a case of 4th metacarpal head collapse of a 19-year-old healthy man. MRI revealed T1 low and T2 high regions in the collapsed 4th metacarpal head, as well as in the right 3rd and left 4th metacarpal head. Our initial diagnosis was occult compression fracture due to avascular necrosis, known as Dieterich's disease. However, pathological findings of surgically resected right 4th metacarpal head were compatible with transient osteoporosis and metacarpal head fracture followed by active tissue repair. The autologous osteochondral transplants from costchondral junction survived and maintained their size and shape even at 10-year follow-up.

Web of Science

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メカニカルストレスに対するヒアルロン酸の軟骨破壊抑制効果の機序の解析

小澤正嗣, 西田圭一郎, 橋詰謙三, 中原龍一, 齋藤太一, 金澤智子, 原田遼三, 町田崇博, 尾崎敏文

日本関節病学会誌 32 ( 3 ) 380 - 380 2013.10

【早期関節リウマチ治療を考える】関節リウマチにおける画像診断の進歩とその役割核磁気共鳴画像(MRI) MRIの早期診断と疾患活動性評価の有用性、その問題点について

中原龍一, 西田圭一郎

Progress in Medicine 33 ( 9 ) 1901 - 1904 2013.9

メカニカルストレスに対するヒアルロン酸の軟骨破壊抑制効果の機序の解析

小澤正嗣, 西田圭一郎, 橋詰謙三, 中原龍一, 斉藤太一, 金澤智子, 原田遼三, 町田崇博, 尾崎敏文

日本整形外科学会雑誌 87 ( 8 ) S1321 - S1321 2013.8

PROSNAP人工肘関節置換術の短期成績

那須義久, 西田圭一郎, 橋詰謙三, 中原龍一, 斎藤太一, 金澤智子, 小澤正嗣, 尾崎敏文

岡山医学会雑誌 125 ( 2 ) 183 - 184 2013.8

【上肢のリウマチ診断と治療】治療生物学的製剤が与えたリウマチ関節外科手術の変化

那須義久, 西田圭一郎

関節外科 32 ( 4 ) 382 - 388 2013.4

関節リウマチの評価法を学ぶ(第2回) 関節レントゲン写真の見方と評価法

原田遼三, 西田圭一郎, 中原龍一, 橋詰謙三

Rheumatology Clinical Research 2 ( 1 ) 53 - 57 2013.4

Language：Japanese Publisher：(株)先端医学社

関節リウマチ(RA)の診断治療において、単純X線による関節病変の評価はその所見に特徴的なものが多く、また病態を反映していることなどもあり有用なツールとして広く使用されている。しかし、生物学的製剤の導入を契機に早期診断また治療効果、寛解評価のための鋭敏な検査が必須となり、単純X線のlimitationのためMRIや超音波検査など他のmodalityとの併用が提唱されている。早期診断には不向きであるが、網羅的評価に長けること、reproducibleであるなど利点も多いため単純X線の見方や評価法について熟慮しておく必要がある。多種の評価法が報告されており、どの評価法を用いるかについては各検査法の長所短所を考慮し、目的に応じた評価法の選択を検討する必要がある。(著者抄録)

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Other Link： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2013&ichushi_jid=J06167&link_issn=&doc_id=20130423530009&doc_link_id=%2Fae6rclid%2F2013%2F000201%2F009%2F0053-0057%26dl%3D0&url=https%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fae6rclid%2F2013%2F000201%2F009%2F0053-0057%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

再発した手関節尺側部痛の1例

金澤智子, 島村安則, 大森敏規, 篠原健介, 原田遼三, 山川泰明, 小澤正嗣, 井上円加, 斉藤太一, 中原龍一, 野田知之, 西田圭一郎, 尾崎敏文

中国・四国整形外科学会雑誌 25 ( 1 ) 245 - 245 2013.4