Faculty Profiles - NISHIDA Keiichiro

Papers - NISHIDA Keiichiro

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松山宜之, 中原龍一, 那須義久, 岡佳純, 千田益生, 西田圭一郎

MEDICAL REHABILITATION ( 244 ) 1 - 7 2020.1

Language：Japanese Publisher：(株)全日本病院出版会

関節リウマチ(RA)手の障害は、スワンネック変形・ボタン穴変形・尺側偏位など多彩であり、一つの手に複数の変形が混在している。その中でも、中手指節(MCP)関節は早期から罹患率が高く関節変形が生じやすく、進行例ではシリコン製インプラントによるMCP人工関節置換術での良好な成績が報告されている。当院では、MCP人工関節置換術に対しては、スタンダードパスを用いて術後療法を行っている。しかし、RA手指においては隣接関節の障害や伸筋腱皮下断裂を伴っていることも多く、進行例の変形では必要に応じて追加手術が同時に実施される。本稿では、通常のMCP人工関節置換術からスワンネック変形・ボタン穴変形・若年者の関節変形の術後リハビリテーションについて概説する。(著者抄録)

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Other Link： https://search-tp.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2020&ichushi_jid=J03505&link_issn=&doc_id=20200124130001&doc_link_id=%2Fap5meree%2F2020%2F000244%2F002%2F0001-0007%26dl%3D0&url=https%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fap5meree%2F2020%2F000244%2F002%2F0001-0007%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

The factors driving self-efficacy in intractable chronic pain patients: a retrospective study. International journal

Hironori Tsuji, Tomoko Tetsunaga, Tomonori Tetsunaga, Keiichiro Nishida, Haruo Misawa, Toshifumi Ozaki

Journal of orthopaedic surgery and research 14 ( 1 ) 473 - 473 2019.12

Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: The fear-avoidance model is a theoretical paradigm for explaining acute and chronic pain. In this model, pain catastrophizing plays an important role. On the other hand, self-efficacy influences whether patients view their pain optimistically, ultimately preventing the conversion of pain into intractable pain. The aim of the present study was to evaluate the factors that influence self-efficacy in patients with chronic pain. METHODS: Study participants included 147 outpatients (35 men, 112 women) with intractable chronic pain who visited our hospital between September 2014 and July 2015. Their mean age was 71.0 (range 32-92) years. Pain sites were as follows: low back, 97 patients; knee, 71 patients; shoulder, 34 patients; and hip, 15 patients. All patients were assessed using the following measures: Numeric Rating Scale (NRS), Pain Catastrophizing Scale (PCS), Hospital Anxiety and Depression Scale (HADS), Pain Disability Assessment Scale (PDAS), and Pain Self-Efficacy Questionnaire (PSEQ). All participants were further divided into two groups based on median PSEQ scores (group L: PSEQ of 35 points or less, n = 74; group H: PSEQ greater than 35 points, n = 73). The factors that influenced self-efficacy in these patients were analyzed using univariate and multiple linear regression analyses. RESULTS: Significant differences were observed in gender; pain duration; and NRS, PDAS, HADS, and PCS scores between group L and group H. Multiple linear regression analysis revealed that self-efficacy was correlated with PDAS score, HADS depression score, and pain duration. CONCLUSIONS: Patients with longer pain duration indicated greater self-efficacy and patients with higher pain disability and depression exhibited lower self-efficacy.

DOI： 10.1186/s13018-019-1535-9

PubMed

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関節リウマチに対するMCP関節人工関節置換術中に手関節部での腱剥離術を要した症例の検討

木曽洋平, 西田圭一郎, 松橋美波, 渡辺雅仁, 沖田駿治, 大橋秀基, 尾崎敏文, 那須義久, 中原龍一

日本関節病学会誌 38 ( 4 ) 471 - 477 2019.12

Language：Japanese Publisher：(一社)日本関節病学会

当院でRA(関節リウマチ)に対しMCP関節人工関節置換術を施行した72例(手術時平均年齢61.8歳±11.9歳)を対象に、術中に手関節背側部の腱剥離術を要した症例について検討した。その結果、術中に手関節背側部の腱剥離術を要した症例は12例(16.7%)であった。更に手関節部での手術歴を有している症例では、15例中6例(40.0%)で術中に腱剥離術の追加が必要であった。手関節手術歴のある例ではEDCの癒着が多い傾向にあり、手術歴のない例では全例でEDMの癒着がみられた。腱剥離(+)群、腱剥離(-)群ともにHAND20、DASHは術後改善傾向を示し、改善量は両群間で有意差は認められなかった。

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患者の満足度を高める関節リウマチ手術関節リウマチの肘関節手術の現状と展望

那須義久, 西田圭一郎

臨床整形外科 54 ( 12 ) 1213 - 1219 2019.12

Language：Japanese Publisher：(株)医学書院

＜文献概要＞人工肘関節置換術(TEA)をはじめ,関節リウマチ(RA)では肘関節の障害に対して手術が必要となる例が以前は多くみられていた.薬物療法の進歩により減少はしているものの,手術適応症例がなくなることはない.本邦では優れた非連結型人工関節が開発され,特に最近いくつかの機種において10年以上にわたって90%を大きく上回るインプラント生存率など,優れた臨床成績が相次いで報告されている.今後は多関節罹患例や高度関節破壊例の減少と,インプラント性能・術式が改善されることでRA肘の手術成績はさらに向上するものと期待される.

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Two cases of high tibial osteotomy in patients with rheumatoid arthritis treated with biologic disease-modifying anti-rheumatic drugs

Takahara, Y., Nishida, K., Nakashima, H., Ochi, N., Uchida, Y., Kato, H., Itani, S., Nakamura, M., Iwasaki, Y., Tsujimura, Y.

Acta Medica Okayama 73 ( 6 ) 537 - 542 2019.12

A high incidence of extensor pollicis brevis insertion into the distal phalanx in rheumatoid arthritis patients who required the surgical reconstruction for thumb boutonnière deformity Reviewed International journal

Shunji Okita, Keiichiro Nishida, Aiji Ohtsuka, Toshifumi Ozaki

Modern Rheumatology 29 ( 6 ) 954 - 958 2019.11

Language：English Publishing type：Research paper (scientific journal) Publisher：Oxford University Press (OUP)

Objectives: The aim of the current study was to investigate the pattern of extensor pollicis brevis (EPB) insertion macroscopically and histologically using cadaveric thumbs, and to compare the incidence of different insertions with that of thumb boutonnière deformity in rheumatoid arthritis (RA) patients who required surgical reconstruction.Methods: We examined 103 thumbs of 58 adult cadavers with no evidence of RA, and reviewed the surgical records of 28 thumbs of 23 RA patients who underwent surgical reconstruction for thumb boutonnière deformity. The incidence of different insertion patterns of the cadaveric thumbs and the RA thumbs were compared using the Fisher's exact test.Results: Macroscopic and histologic examination revealed that the insertion patterns of EPB could be divided into three groups: insertion into the base of the proximal phalanx (Type P1), integration of EPB into the dorsal fibrocartilage of the MCP joint (Type P2), and insertion into the distal phalanx (Type D). The incidence of Type D was significantly higher in RA patients with thumb boutonnière deformity (64%) than that in the non-RA cadavers (29%; P < .05).Conclusion: EPB is inserted into the distal phalanx more frequently in RA patients who require surgery for thumb boutonnière deformity than non-RA cadavers, suggesting an additional possible mechanism of this deformity.

DOI： 10.1080/14397595.2018.1532484

PubMed

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慢性疼痛のFear-Avoidanceモデルにおける各因子とロコモ25との関連についての検討

辻寛謙, 鉄永倫子, 鉄永智紀, 辻暁里, 折田沙穂, 西田圭一郎, 尾崎敏文

Journal of Musculoskeletal Pain Research 11 ( 4 ) S61 - S61 2019.11

慢性疼痛患者における活動性及びQOLはロコモ25と相関するか

辻暁里, 鉄永倫子, 鉄永智紀, 辻寛謙, 折田沙穂, 西田圭一郎, 尾崎敏文

Journal of Musculoskeletal Pain Research 11 ( 4 ) S60 - S60 2019.11

再移植の実施と非実施による感染症の危険因子と感染率の比較(Risk Factors for Infection and Comparison of Infection Rate with and without Replantation)

斎藤太一, 根津智史, 松橋美波, 島村安則, 西田圭一郎, 湯本哲也, 中尾篤典, 尾崎敏文

日本マイクロサージャリー学会学術集会プログラム・抄録集 46回 127 - 127 2019.11

慢性疼痛外来において初診時付き添いの有無と各種疼痛スコアとの関連性

折田沙穂, 鉄永倫子, 鉄永智紀, 辻寛謙, 辻暁里, 西田圭一郎, 尾崎敏文

Journal of Musculoskeletal Pain Research 11 ( 4 ) S99 - S99 2019.11

Mechanical strain attenuates cytokine-induced ADAMTS9 expression via transient receptor potential vanilloid type 1. Reviewed International journal

Takashi Ohtsuki, Akira Shinaoka, Kanae Kumagishi-Shinaoka, Keiichi Asano, Omer Faruk Hatipoglu, Junko Inagaki, Ken Takahashi, Toshitaka Oohashi, Keiichiro Nishida, Keiji Naruse, Satoshi Hirohata

Experimental cell research 383 ( 2 ) 111556 - 111556 2019.10

Language：English

The synovial fluids of patients with osteoarthritis (OA) contain elevated levels of inflammatory cytokines, which induce the expression of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) and of the matrix metalloproteinase (MMP) in chondrocytes. Mechanical strain has varying effects on organisms depending on the strength, cycle, and duration of the stressor; however, it is unclear under inflammatory stimulation how mechanical strain act on. Here, we show that mechanical strain attenuates inflammatory cytokine-induced expression of matrix-degrading enzymes. Cyclic tensile strain (CTS), as a mechanical stressor, attenuated interleukin (IL)-1β and tumor necrosis factor (TNF)-α-induced mRNA expression of ADAMTS4, ADAMTS9, and MMP-13 in normal chondrocytes (NHAC-kn) and in a chondrocytic cell line (OUMS-27). This effect was abolished by treating cells with mechano-gated channel inhibitors, such as gadolinium, transient receptor potential (TRP) family inhibitor, ruthenium red, and with pharmacological and small interfering RNA-mediated TRPV1 inhibition. Furthermore, nuclear factor κB (NF-κB) translocation from the cytoplasm to the nucleus resulting from cytokine stimulation was also abolished by CTS. These findings suggest that mechanosensors such as the TRPV protein are potential therapeutic targets in treating OA.

DOI： 10.1016/j.yexcr.2019.111556

Web of Science

PubMed

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関節リウマチ前足部手術に対する術式別の臨床成績の比較

渡辺雅仁, 西田圭一郎, 那須義久, 中原龍一, 木曽洋平, 松橋美波, 尾崎敏文

中国・四国整形外科学会雑誌 31 ( 3 ) 322 - 322 2019.10