Faculty Profiles - MORIZANE Yuki

Papers - MORIZANE Yuki

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Reply. International journal

Sayumi Kanzaki, Yuki Kanzaki, Shinichiro Doi, Ryo Matoba, Shuhei Kimura, Mio Hosokawa, Yusuke Shiode, Kosuke Takahashi, Atsushi Fujiwara, Ippei Takasu, Yuki Morizane

Ophthalmology. Retina 6 ( 7 ) 645 - 645 2022.7

Bilateral Blunt Ocular Trauma Caused by an Exercise Resistance Band during Muscle Building Exercise for Swimming.

Kanazu Ariyasu, Shuhei Kimura, Ryo Matoba, Mio Morizane Hosokawa, Yusuke Shiode, Shinichiro Doi, Yuki Kanzaki, Yuki Morizane

Acta medica Okayama 76 ( 3 ) 349 - 354 2022.6

Language：English

An 18-year-old male high school student presented to our clinic with bilateral blunt ocular trauma caused by an exercise resistance band (ERB) during a muscle-building exercise. Best-corrected decimal visual acuities (BCVAs) for right and left eyes were light perception and 0.15, respectively. The right eye was operated 10 days after injury for persistent vitreous hemorrhage, and the left eye 5 months later because of macular hole onset. After 36 months, the right eye showed extensive retinal degeneration (BCVA 0.04), and the left eye macular hole closure (BCVA 1.2). ERBs should be used cautiously as they can cause serious ocular trauma.

DOI： 10.18926/AMO/63747

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Postoperative follow-up of submacular hemorrhage displacement treated with vitrectomy and subretinal injection of tissue plasminogen activator: ultrawide-field fundus autofluorescence imaging in gas-filled eyes.

Yosuke Fukuda, Shintaro Nakao, Ri-Ichiro Kohno, Keijiro Ishikawa, Sakurako Shimokawa, Satomi Shiose, Atsunobu Takeda, Yuki Morizane, Koh-Hei Sonoda

Japanese journal of ophthalmology 66 ( 3 ) 264 - 270 2022.5

Language：English Publishing type：Research paper (scientific journal)

PURPOSE: To investigate the utility of Optos ultrawide-field fundus autofluorescence (UWF-FAF) imaging for postoperative follow-up of gas-filled eyes after vitrectomy with subretinal tissue-plasminogen activator (t-PA) injection for subretinal hemorrhage (SRH) displacement. STUDY DESIGN: Retrospective consecutive case series. METHODS: This study included 24 eyes with SRH. Vitrectomy with subretinal t-PA injection was performed, followed by postoperative prone positioning. FAF images acquired using Optos California were examined and the SRH occupancy in the macula was calculated. The main outcome measures were displacement rate and direction of SRH for 3 days postoperatively, and postoperative best-corrected visual acuity (BCVA). RESULTS: The postoperative BCVA ranged from improvement (23 eyes; 95.8%) to no change (one eye; 4.2%). Analysis was done using postoperative Optos FAF images for 20 eyes (83.3%). Postoperative SRH occupancy was significantly reduced, by 27.4%, compared with the preoperative occupancy (P = 0.03). A statistically significant reduction was found between the preoperative and postoperative day (POD)1 (P = 0.04), but not between POD1 and POD2 (P = 0.7), or between POD2 and POD3 (P = 1.0). CONCLUSION: UWF-FAF imaging is useful for postoperative follow-up of gas-filled eyes after vitrectomy with subretinal t-PA injection for SRH displacement.

DOI： 10.1007/s10384-022-00910-7

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Treatment of diabetic macular edema in real-world clinical practice: The effect of aging.

Sentaro Kusuhara, Masahiko Shimura, Shigehiko Kitano, Masahiko Sugimoto, Daisuke Muramatsu, Harumi Fukushima, Yoshihiro Takamura, Makiko Matsumoto, Masahide Kokado, Jiro Kogo, Mariko Sasaki, Yuki Morizane, Takuya Utsumi, Osamu Kotake, Takashi Koto, Hiroto Terasaki, Takao Hirano, Hiroto Ishikawa, Yoshinori Mitamura, Fumiki Okamoto, Takamasa Kinoshita, Kazuhiro Kimura, Kenji Yamashiro, Yukihiko Suzuki, Taiichi Hikichi, Noriaki Washio, Tomohito Sato, Kishiko Ohkoshi, Hiroki Tsujinaka, Mineo Kondo, Hitoshi Takagi, Toshinori Murata, Taiji Sakamoto

Journal of diabetes investigation 13 ( 8 ) 1339 - 1346 2022.4

Language：English Publishing type：Research paper (scientific journal)

AIMS/INTRODUCTION: In older patients, the management of diabetic macular edema (DME) can be complicated by comorbidities, geriatric syndrome, and socioeconomic status. This study aims to evaluate the effects of aging on the management of DME. MATERIALS AND METHODS: This is a real-world clinical study including 1,552 patients with treatment-naïve center-involved DME. The patients were categorized into 4 categories by age at baseline (C1, <55; C2, 55-64; C3, 65-74; and C4, ≥75 years). The outcomes were the change in logarithm of the minimum angle of resolution best-corrected visual acuity (logMAR BCVA) and central retinal thickness (CRT), and the number of treatments from baseline to 2 years. RESULTS: From baseline to 2 years, the mean changes in logMAR BCVA from baseline to 2 years were -0.01 in C1, -0.06 in C2, -0.07 in C3, and 0.01 in C4 (P = 0.016), and the mean changes in CRT were -136.2 μm in C1, -108.8 μm in C2, -100.6 μm in C3, and -89.5 μm in C4 (P = 0.008). Treatments applied in the 2 year period exhibited decreasing trends with increasing age category on the number of intravitreal injections of anti-VEGF agents (P = 0.06), selecting local corticosteroid injection (P = 0.031), vitrectomy (P < 0.001), and laser photocoagulation outside the great vascular arcade (P < 0.001). CONCLUSIONS: Compared with younger patients with DME, patients with DME aged ≥75 years showed less frequent treatment, a lower BCVA gain, and a smaller CRT decrease. The management and visual outcome in older patients with DME would be unsatisfactory in real-world clinical practice.

DOI： 10.1111/jdi.13801

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網膜細動脈瘤破裂による網膜内出血が網膜感度に及ぼす影響

赤塚陸, 土居真一郎, 木村修平, 塩出雄亮, 細川海音, 的場亮, 神崎勇希, 森實祐基

日本眼科学会雑誌 126 ( 臨増 ) 171 - 171 2022.3

黄斑上膜における最大網膜皺襞深度と黄斑局所網膜電図および網膜層厚との関係

神崎勇希, 的場亮, 木村修平, 細川海音, 塩出雄亮, 土居真一郎, 谷川篤宏, 森實祐基

日本眼科学会雑誌 126 ( 臨増 ) 196 - 196 2022.3

網膜剥離眼における眼軸長の測定法の検討

木村修平, 後藤保人, 金永圭祐, 細川海音, 塩出雄亮, 土居真一郎, 的場亮, 神崎勇希, 鈴木越治, 森實祐基

日本眼科学会雑誌 126 ( 臨増 ) 219 - 219 2022.3

光干渉断層計en face画像を用いた分層黄斑円孔関連疾患の解析

三野麻以, 的場亮, 木村修平, 細川海音, 塩出雄亮, 土居真一郎, 神崎勇希, 森實祐基

日本眼科学会雑誌 126 ( 臨増 ) 235 - 235 2022.3

水泳の筋力トレーニング中にエクササイズバンドによって重度の両眼外傷を来した一例

有安奏, 木村修平, 的場亮, 細川海音, 塩出雄亮, 土居真一郎, 神崎勇希, 森實祐基

日本眼科学会雑誌 126 ( 臨増 ) 283 - 283 2022.3

2019年度の全国新規視覚障害認定疫学調査

的場亮, 守本典子, 川崎良, 金永圭祐, 坂手澪, 稲垣明日香, 後藤保人, 山下英俊, 坂本泰二, 森實祐基

日本眼科学会雑誌 126 ( 臨増 ) 307 - 307 2022.3

黄斑上膜における最大網膜皺襞深度と黄斑局所網膜電図および網膜層厚との関係

神崎勇希, 的場亮, 木村修平, 細川海音, 塩出雄亮, 土居真一郎, 谷川篤宏, 森實祐基

日本眼科学会雑誌 126 ( 臨増 ) 196 - 196 2022.3

水泳の筋力トレーニング中にエクササイズバンドによって重度の両眼外傷を来した一例

有安奏, 木村修平, 的場亮, 細川海音, 塩出雄亮, 土居真一郎, 神崎勇希, 森實祐基

日本眼科学会雑誌 126 ( 臨増 ) 283 - 283 2022.3

網膜剥離眼における眼軸長の測定法の検討

木村修平, 後藤保人, 金永圭祐, 細川海音, 塩出雄亮, 土居真一郎, 的場亮, 神崎勇希, 鈴木越治, 森實祐基

日本眼科学会雑誌 126 ( 臨増 ) 219 - 219 2022.3

光干渉断層計en face画像を用いた分層黄斑円孔関連疾患の解析

三野麻以, 的場亮, 木村修平, 細川海音, 塩出雄亮, 土居真一郎, 神崎勇希, 森實祐基

日本眼科学会雑誌 126 ( 臨増 ) 235 - 235 2022.3

網膜細動脈瘤破裂による網膜内出血が網膜感度に及ぼす影響

赤塚陸, 土居真一郎, 木村修平, 塩出雄亮, 細川海音, 的場亮, 神崎勇希, 森實祐基

日本眼科学会雑誌 126 ( 臨増 ) 171 - 171 2022.3

Objective and quantitative estimation of the optimal timing for epiretinal membrane surgery on the basis of metamorphopsia. International journal

Yuki Kanzaki, Shinichiro Doi, Ryo Matoba, Sayumi Kanzaki, Shuhei Kimura, Mio M Hosokawa, Yusuke Shiode, Ippei Takasu, Yuki Morizane

Retina (Philadelphia, Pa.) 42 ( 4 ) 704 - 711 2021.12

Language：English Publishing type：Research paper (scientific journal)

PURPOSE: To establish an objective and quantitative biomarker of metamorphopsia in epiretinal membranes (ERMs) and determine the optimal timing for ERM surgery. METHODS: Retrospectively, 172 eyes with ERM were reviewed. Retinal folds due to tangential traction by ERM were visualized by en face optical coherence tomography (OCT). The maximum depth of retinal folds (MDRF) within the parafovea was quantified. Metamorphopsia was quantified by M-CHARTS. The change in the distance between the retinal vessels after ERM surgery and the preoperative total depth of retinal folds between the vessels were quantified using en face OCT and OCT angiography. RESULTS: Significant correlations were observed between preoperative MDRF and M-CHARTS scores before and at 6 months after surgery (r=0.617 and 0.460, respectively; P<0.001) and change in the distance between the retinal vessels after ERM surgery and preoperative total depth of retinal folds between the vessels (r=0.471, P=0.013). The preoperative MDRF values at which M-CHARTS scores were 0.5 before and 6 months after surgery were 69 μm and 118 μm, respectively. CONCLUSION: MDRF is an objective and quantitative biomarker of metamorphopsia in ERM. To maintain patients' quality of vision, ERM surgery may be performed when the preoperative MDRF ranges between 69 and 118 μm.

DOI： 10.1097/IAE.0000000000003401

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Sublingual Gland Carcinoma Revealed by Choroidal Metastasis.

Tetsuro Morita, Yusuke Shiode, Shuhei Kimura, Mio Hosokawa, Shinichiro Doi, Kosuke Takahashi, Ryo Matoba, Yuki Kanzaki, Masahiro Tabata, Yuki Morizane

Acta medica Okayama 75 ( 6 ) 741 - 744 2021.12

Language：English

A 65-year-old man presented with a 1-week history of left eye distortion. An elevated choroidal lesion covering 6 disc diameters was found in the posterior retina of the left eye. Systemic examination revealed sublingual gland carcinoma and multiple lung metastases, and the diagnosis was choroidal metastasis from sublingual gland carcinoma. Following chemotherapy and radiation therapy, the choroidal lesion shrunk and the patient's visual acuity improved. The patient died 23 months after his first visit. To the best of our knowledge, this is the first reported case of choroidal metastasis from sublingual gland carcinoma.

DOI： 10.18926/AMO/62815

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【眼科手術Q&A】網膜・硝子体黄斑下出血に対する硝子体手術について、とくに黄斑円孔合併例への対処法を教えてください

木村修平, 森實祐基

あたらしい眼科 38 ( 臨増 ) 127 - 132 2021.12

Corynebacterium ocular infection after Baerveldt glaucoma implant surgery: treatment involving immediate tube withdrawal and temporary subconjunctival tube placement: a case report. International journal

Naruka Mitsui, Kae Sugihara, Jiro Seguchi, Etsuo Chihara, Yuki Morizane, Akiko Narita

BMC ophthalmology 21 ( 1 ) 368 - 368 2021.10

Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: We report a case of Corynebacterium endophthalmitis secondary to tube exposure following Baerveldt glaucoma implant surgery that was successfully treated with prompt tube withdrawal and temporary subconjunctival tube placement without removing the glaucoma drainage device. CASE PRESENTATION: A 65-year-old Japanese man with secondary glaucoma underwent glaucoma drainage device surgery with a donor scleral patch graft in the inferonasal quadrant of his right eye. Ten months after surgery, he presented with tube exposure due to dehiscence of the overlying conjunctiva and erosion of the scleral patch graft. Eleven days later, mild inflammation was found in the anterior chamber and anterior vitreous body, with the root of the tube surrounded by a plaque at the site of insertion in the anterior chamber. He was diagnosed with infectious endophthalmitis secondary to tube exposure. Two days later, since medical therapy was ineffective, the tube was withdrawn from the anterior chamber and irrigated with a polyvinyl alcohol-iodine solution, and the tube was tucked into the subconjunctival space. Complete resolution of the infection was achieved 1.5 months later. The tube was reinserted nasally into the anterior chamber and covered with a scleral patch graft and a free limbal conjunctival autograft. Thereafter, there has been no recurrence of infection or tube exposure. Twenty eight months after tube reinsertion, his right best-corrected visual acuity was 20/50 and intraocular pressure was 12 mmHg. CONCLUSION: Prompt tube withdrawal and temporary subconjunctival tube placement followed by tube reinsertion may be effective for endophthalmitis associated with tube exposure after glaucoma drainage device surgery.

DOI： 10.1186/s12886-021-02136-6

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Response to the letter to the editor: "Coronal plane OCT imaging and vision in macular pucker". International journal

Ryo Matoba, Yuki Kanzaki, Shinichiro Doi, Yuki Morizane

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 260 ( 7 ) 2381 - 2381 2021.10

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Papers - MORIZANE Yuki