Faculty Profiles - NAKATSUKA Mikiya

MISC - NAKATSUKA Mikiya

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Autonomic response in women with psychosomatic symptoms: short-term frequency, domain analysis of heart rate variability in ergometer loading

Yuka Goto a, Hiroyuki Okuda a, Mikiya Nakatsuka a

Journal of the Japan Society of Neurovegetative Research 46 ( 4 ) 341 - 348 2009

新連載性同一性障害の生徒の問題に向き合う第2回思春期における性同一性障害の子ども

中塚幹也

中学保健ニュース 2009

新連載性同一性障害の生徒の問題に向き合う第1回性同一性障害をめぐる社会的変遷

中塚幹也

高校保健ニュース 2009

新連載性同一性障害の生徒の問題に向き合う第1回性同一性障害をめぐる社会的変遷

中塚幹也

中学保健ニュース 2009

Autonomic response in women with psychosomatic symptoms: short-term frequency, domain analysis of heart rate variability in ergometer loading

Yuka Goto a, Hiroyuki Okuda a, Mikiya Nakatsuka a

Journal of the Japan Society of Neurovegetative Research 46 ( 4 ) 341 - 348 2009

子宮卵管造影法で疎通性を認めた卵管の腹腔鏡による検討

鎌田泰彦, 菊池由加子, 田淵和宏, 小谷早葉子, 清水恵子, 野口聡一, 中塚幹也, 平松祐司

現代産婦人科 2009

不育症女性に対する精神的支援に関する研究―流・死産後の環境と不育症女性の心理―

中塚幹也

厚生労働科学研究費補助金（子ども家庭総合研究事業）「不育症治療に関する再評価と新たなる治療法の開発に関する研究」総括研究報告書（平成20年度） 2009

小・中学校の教員における性同一性障害に関する認識と対応

菊池由加子, 新井富士美, 松田美和, 清水恵子, 中塚幹也

GID（性同一性障害）学会雑誌 2 64 - 66 2009

セクシャルマイノリティの私たちから，先生へ：子どもの頃は，本当の自分でいられなかった

中塚幹也

Proud in 香川リーフレット 2009

日本女医会子育て委員会（ゆいネット）連絡協議会 in 岡山2009 10代の性の健康支援ネットワークにおいて岡山大学大学院保健学研究科が関与できる可能性があること

中塚幹也

独立行政法人社会福祉機構「子育て支援基金」助成事業社団法人日本女医会子育て委員会「十代の性の健康」支援ネットワーク作り事業平成20年度報告書 2009

シンポジウム：マイナス2歳からはじまる子育て支援医療スタッフによる子育てハイリスク群への対応

中塚幹也

第5回子育てネットワークin岡山2008報告書 2009

ワークショップ12「不育症の新たな原因探索と治療」本邦における不育症のリスク因子とその予後に関する研究.

中塚幹也

日本周産期・新生児医学会雑誌 2009

P1-226 子宮内膜症例の血清中の酸化LDL-β2GPI-CRP複合体の検討(Group31 子宮内膜症2,一般演題,第61回日本産科婦人科学会学術講演会)

佐々木愛子, 中塚幹也, 松田美和, 小谷早葉子, 清水恵子, 鎌田泰彦, 平松祐司, 野口聡一

日本産科婦人科學會雜誌 61 ( 2 ) 521 - 521 2009

P2-290 5-HT(セロトニン)系の子宮内膜症・腺筋症性疼痛への関与(Group69 子宮内膜症3,一般演題,第61回日本産科婦人科学会学術講演会)

鎌田泰彦, 清水恵子, 松田美和, 小谷早葉子, 佐々木愛子, 中塚幹也, 平松祐司

日本産科婦人科學會雜誌 61 ( 2 ) 622 - 622 2009

P2-293 不妊症症例における月経中のCA125値と子宮内膜症の存在(Group69 子宮内膜症3,一般演題,第61回日本産科婦人科学会学術講演会)

國宗和歌菜, 中塚幹也, 佐々木愛子, 小谷早葉子, 松田美和, 清水恵子, 鎌田泰彦, 平松祐司, 野口聡一

日本産科婦人科學會雜誌 61 ( 2 ) 623 - 623 2009

Vaginoplasty with a Pudendal-Thigh Flap in Intersexuals

Yuzaburo Namba, Narushi Sugiyama, Shuji Yamashita, Kenjiro Hasegawa, Yoshihiro Kimata, Mikiya Nakatsuka

ACTA MEDICA OKAYAMA 62 ( 6 ) 415 - 419 2008.12

Language：English Publisher：OKAYAMA UNIV MED SCHOOL

We treated 2 different types of intersexual patients who underwent a vaginoplasty with the pudendal-thigh flap. One was a female with testicular feminization syndrome for whom we reconstructed the total vagina with a pudendal-thigh flap, and the other was a female with an adrenogenital syndrome for whom we enlarged the introitus of the vagina with the same approach. There were no complications such as a flap necrosis. In addition, there was no stricture of the neo-vagina and no urinary problem.

DOI： 10.18926/AMO/30948

Web of Science

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Increased arterial stiffness in female-to-male transsexuals treated with androgen

Yayoi Emi, Miwa Adachi, Aiko Sasaki, Yoshio Nakamura, Mikiya Nakatsuka

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH 34 ( 5 ) 890 - 897 2008.10

Language：English Publisher：WILEY-BLACKWELL

Aim: Female-to-male (FTM) transsexuals are treated with long-term and high-dose androgen. Although androgen is known to affect the cardiovascular system, vascular function in FTM transsexuals has not been fully elucidated. The aim of this study was to evaluate the arterial stiffness in FTM transsexuals treated with androgen.
Methods: We evaluated the arterial stiffness in 111 FTM transsexuals (63 untreated FTM transsexuals and 48 FTM transsexuals treated with androgen) using a volume-plethysmographic apparatus equipped with a multi-element applanation tonometry sensor.
Results: There were no significant differences in age, body mass index and heart rate between the untreated FTM transsexuals and those treated with androgen. The systolic and diastolic blood pressures in FTM transsexuals treated with androgen were significantly higher than those in untreated FTM transsexuals. The level of brachial-ankle pulse wave velocity in FTM transsexuals treated with androgen (1202.8 +/- 138.2 cm/s) was significantly higher than that in untreated FTM transsexuals (1080.2 +/- 113.7 cm/s) while there was no significant difference in the carotid augmentation index between untreated FTM transsexuals and those treated with androgen.
Conclusions: Long-term and high-dose administration of androgen is likely to cause increased arterial stiffness in FTM transsexuals. To prevent atherosclerosis and cardiovascular events, a periodic checkup and pharmacological therapies for hypertension should be tailored on an individual basis.

DOI： 10.1111/j.1447-0756.2008.00857.x

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Study of Views on Posthumous Reproduction, Focusing on Its Relation with Views on Family and Religion in Modern Japan

Noriyuki Ueda, Nobutaka Kushi, Mikiya Nakatsuka, Tatsuyuki Ogawa, Yoshiko Nakanishi, Keisuke Shishido, Tsuyoshi Awaya

ACTA MEDICA OKAYAMA 62 ( 5 ) 285 - 296 2008.10

Language：English Publisher：OKAYAMA UNIV MED SCHOOL

Posthumous reproduction has been performed in Japan several times, without sufficient civic discussion on its appropriateness or legislative regulation. There have even been several lawsuits on posthumous acknowledgment (in which a baby born to a deceased father has the same birthright as a baby born to a living father), and some judgments have proposed the need to develop societal agreement on posthumous reproduction and suggested legislative settlement. With this background, this study aims to clarify the views of the Japanese people regarding posthumous reproduction. In December 2007, we distributed a questionnaire on posthumous reproduction in relation to beliefs about family and religion to 32 universities across the country, and received 3,719 replies. It was found that about 60% of respondents agreed with posthumous reproduction. Statistical analysis was applied to the relationship between this overall position on posthumous reproduction and views on assisted reproduction technologies, family, religion, and so on. The degree of support for posthumous reproduction was strongly correlated with the degree of affirmation of assisted reproduction technologies and a liberal worldview with emphasis on self-determination. On the other hand, there was also a strong correlation with having a traditional view of family, such as family succession. The degree of support for posthumous reproduction was also highly correlated with the intimacy among family members, underlying which was a strong connection to the traditional religious belief in Japan that deceased family members watch the living ones. The view on posthumous reproduction is culturally complex and cannot be explained by a simple dichotomy between traditional conservatives and liberals.

DOI： 10.18926/AMO/30967

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Adverse effects of advanced glycation end products on embryonal development

Lin Hao, Soichi Noguchi, Yasuhiko Kamada, Aiko Sasaki, Miwa Matsuda, Keiko Shimizu, Yuji Hiramatsu, Mikiya Nakatsuka

ACTA MEDICA OKAYAMA 62 ( 2 ) 93 - 99 2008.4

Language：English Publisher：OKAYAMA UNIV MED SCHOOL

We studied the effects of advanced glycation end products (AGEs), which are known to accumulate in patients with diabetes, autoimmune diseases, or those who smoke, on embryonal development. Pronuclear (PN) embryos were obtained by flushing the fallopian tubes of rats after superovulation and mating. The cleavage rate and blastocyst yield were evaluated at 24, 72, 96, and 120 h of culture. Glyoxal, an AGE-forming aldehyde, suppressed embryonal development at every stage from PN to blastocyst in a concentration-dependent manner. The cleavage rate of the embryo was also significantly decreased by treatment with glyoxal at concentrations of 1 mM or higher. The blastocyst yield was significantly decreased by treatment with glyoxal at concentrations of 0.5 mM or higher. N-acetyl-L-cysteine (L-NAC) at I mM significantly suppressed the glyoxal-induced embryonal toxicity. BSA-AGEs at 5 mu g/ml or higher concentration significantly reduced the cleavage rate and blastocyst yield compared to those for BSA-treated embryos. L-NAC at I mM significantly suppressed BSA-AGE-induced embryonal toxicity. Because AGEs are embryo-toxic, AGE contamination may influence the pregnancy rate of in vitro fertilization and embryo transfer. AGEs, which are increased in women under pathological conditions, may also be involved in their infertility.

DOI： 10.18926/AMO/30960

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2008年度桃太郎フォーラムXIを終えて

中塚幹也

桃太郎フォーラムXI「受けたい授業を創る：教授法改善のヒント」報告書 2008

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