研究者詳細 - 柳　文修

MISC - 柳　文修

分割表示 252 件中 61 - 80 件目／全件表示 >>

口腔癌マウスモデルでの抗EGFR療法における分子イメージング解析

村上純, 此内浩信, 柳文修, 久富美紀, 畦坪輝寿, 藤田麻里子, 岡田俊輔, 苔口進, 竹中文章, 浅海淳一

日本口腔科学会雑誌 64 ( 2 ) 189 - 190 2015年7月

顎関節部MRI検査で指摘可能であった偶発的頭蓋内病変についての臨床的検討

藤田麻里子, 柳文修, Panelli Santos Karina Cecilia, 久富美紀, 村上純, 此内浩信, 畦坪輝寿, 岡田俊輔, Sugianto Irfan, 浅海淳一

歯科放射線 55 ( 増刊 ) 62 - 62 2015年4月

口腔癌マウスモデルでのセツキシマブを用いた分子イメージング解析

村上純, 此内浩信, 柳文修, 久富美紀, 苔口進, 竹中文章, 畦坪輝寿, 藤田麻里子, 岡田俊輔, 浅海淳一

歯科放射線 55 ( 増刊 ) 70 - 70 2015年4月

MRIデータから生成した擬似セファログラムの有用性に関する研究

柳文修, 田井尚子, 田井規能, 飯田征二, 水谷雅英, 森谷徳文, 原麻里奈, 岡田俊輔, 村上純, 久富美紀, 此内浩信, 浅海淳一

Japanese Journal of Diagnostic Imaging 33 ( 1 ) 102 - 102 2015年2月

静止性骨空洞のX線学的検討

久富美紀, 此内浩信, 柳文修, 村上純, 畦坪輝寿, 藤田麻里子, 岡田俊輔, 浅海淳一

日本口腔診断学会雑誌 28 ( 1 ) 104 - 104 2015年2月

新規抗癌剤KNK437による抗腫瘍増大効果・転移阻害効果に関するin vivoにおける検討

畦坪輝寿, 村上純, 此内浩信, 柳文修, 久富美紀, 藤田麻里子, 岡田俊輔, 浅海淳一

日本口腔診断学会雑誌 28 ( 1 ) 95 - 95 2015年2月

A case of adenoid cystic carcinoma associated with IgG4-related disease. 国際誌

Tsuyoshi Shimo, Mayumi Yao, Yuichiro Takebe, Yuko Ono, Kyoichi Obata, Naito Kurio, Soichiro Ibaragi, Norie Yoshioka, Koji Kishimoto, Yoshinobu Yanagi, Hitoshi Nagatsuka, Akira Sasaki

International journal of surgery case reports 10 ( 1 ) 12 - 6 2015年

記述言語：英語出版者・発行元：ELSEVIER SCI LTD

INTRODUCTION: Immunoglobulin G4-related disease (IgG4-RD) is an inflammatory condition associated with elevated serum IgG4 levels and tissue infiltration by IgG4-expressing plasma cells. We present a case of adenoid cystic carcinoma (ACC) of the submandibular gland with possible involvement of IgG4-RD. PRESENTATION OF CASE: The patient was a 59-year-old man presenting with a swollen right submandibular gland. Laboratory tests revealed IgG4 levels of 176mg/dl (reference range: 4.8-105). An initial open biopsy for histological diagnosis showed chronic sialadenitis. The region was monitored on an outpatient basis, and finally the right submandibular was totally resected because malignant tumor could not be excluded. Histological examination of the submandibular gland showed an ACC with lymphocytic infiltration containing many IgG4-positive plasma cells in the tumor stroma. DISCUSSION: We have described a case that indicated a possible involvement of ACC with IgG4-RD. This allows us to speculate that longstanding IgG4-RD may progress to malignancy or infiltration of IgG4-positive plasma cells through the signals of tumor stimuli. Further investigations are required to determine the potential pathogenic mechanism underlying this unique tumor. CONCLUSION: This case underscores that caution is needed in the diagnosis of masses with high serum IgG4 levels, as the differential diagnosis includes malignancy.

DOI： 10.1016/j.ijscr.2015.01.022

静止性骨空洞のX線学的検討

久富美紀, 此内浩信, 柳文修, 村上純, 畦坪輝寿, 藤田麻里子, 岡田俊輔, 浅海淳一

日本口腔内科学会雑誌 20 ( 2 ) 113 - 113 2014年12月

表在性頬粘膜扁平上皮癌の放射線治療計画にスペーサーを利用した一例

松原理紗, 松崎秀信, 柳文修, 佐藤晃子, 原麻里奈, 澤邊麻友子, 水谷雅英, 池田篤司, 飯田征二, 浅海淳一

岡山歯学会雑誌 33 ( 2 ) 48 - 48 2014年12月

新規抗癌剤KNK437による抗腫瘍増大効果・転移阻害効果に関するin vivoにおける検討

畦坪輝寿, 村上純, 此内浩信, 柳文修, 久富美紀, 藤田麻里子, 岡田俊輔, 浅海淳一

日本口腔内科学会雑誌 20 ( 2 ) 104 - 104 2014年12月

車椅子から歯科用チェアーへの移乗時の転倒転落インシデントに対する岡山大学病院としての取り組み

白井肇, 江草正彦, 柳文修, 丸山雅道, 森田幸子, 鉄永倫子, 築山尚司, 岩月啓氏, 鳥井康弘, 飯田征二

医療の質・安全学会誌 9 ( Suppl. ) 258 - 258 2014年10月

口腔癌に対するBCG生菌と5-FU併用療法による延命効果の検討

村上純, 此内浩信, 柳文修, 久富美紀, 畦坪輝寿, 藤田麻里子, 浅海淳一

日本口腔科学会雑誌 63 ( 4 ) 429 - 429 2014年9月

Audience Response System(クリッカー)の活用による「歯科放射線学」における参加型講義(第2報)

此内浩信, 浅海淳一, 柳文修, 久富美紀, 村上純, 畦坪輝寿, 藤田麻里子

日本歯科医学教育学会総会・学術大会プログラム・抄録集 33回 133 - 133 2014年7月

口腔癌細胞株担癌マウスに対するBCG生菌と5-FU併用療法による延命効果の検討

村上純, 大原直也, 中山真彰, 辻極秀次, 長塚仁, 此内浩信, 柳文修, 苔口進, 久富美紀, 藤田麻里子, 畦坪輝寿, 浅海淳一

日本癌治療学会誌 49 ( 3 ) 1533 - 1533 2014年6月

エナメル上皮腫と角化嚢胞性歯原性腫瘍の鑑別におけるMRIの有用性について嚢胞様成分内のSD値の比較は鑑別に有用であるか

藤田麻里子, 柳文修, 此内浩信, 久富美紀, 村上純, 畦坪輝寿, 岡田俊輔, 若狭亨, 浅海淳一

日本口腔診断学会雑誌 27 ( 1 ) 105 - 105 2014年2月

顎骨病変精査中に発見された甲状腺乳頭癌の一例

岡田俊輔, 柳文修, 此内浩信, 久富美紀, 村上純, 畦坪輝寿, 藤田麻里子, 片嶋和典, 浅海淳一

日本口腔診断学会雑誌 27 ( 1 ) 99 - 100 2014年2月

IgG4高値を示し、診断に苦慮した顎下腺癌の1例

志茂剛, 矢尾真弓, 小野裕子, 岸本晃治, 柳文修, 浅海淳一, 佐々木朗

日本口腔診断学会雑誌 27 ( 1 ) 99 - 99 2014年2月

Diagnostic value of MR imaging for dentigerous cysts

Hironobu Konouchi, Jun-ichi Asaumi, Yoshinobu Yanagi, Miki Hisatomi, Emiko Saito Arita, Plauto Christopher Aranha Watanabe, Jun Murakami, Teruhisa Unetsubo, Mariko Fujita, Shunsuke Okada, Hidenobu Matsuzaki, Toshihiko Takenobu, Toru Wakasa

ORAL RADIOLOGY 30 ( 1 ) 13 - 19 2014年1月

記述言語：英語出版者・発行元：SPRINGER

It is known that the magnetic resonance (MR) imaging features of dentigerous cysts (DCs) are the same as those of other cysts. The cavities of DCs generally show low signal intensity (SI) on T1-weighted imaging (T1WI). However, in our experience, DCs often show high SI on T1WI, rendering them difficult to distinguish from keratocystic odontogenic tumors (KCOTs). In this study, we evaluated seven cases of DC and 23 cases of KCOT to assess whether MR imaging can provide additional information for the differential diagnosis of DC and KCOT.Two trials were evaluated. The first trial was an analysis of the cystic cavity SI on T1WI. To compare the SI between patients, we performed T1WI with contrast (T1c). The second trial analyzed the SI uniformity (U (I )) pound on T1WI, T2-weighted imaging (T2WI), and short inversion time inversion recovery (STIR) images of the cystic cavity, because it has been reported that an MR imaging feature of KCOT is heterogeneous SI. Statistical analyses were performed using the Mann-Whitney U test and a receiver operating characteristic (ROC) curve.The T1c values of DCs were significantly higher than those for KCOTs. The U (I ) pound values on T1WI and STIR images were significantly higher for DCs than for KCOTs. The T1c cutoff values (0.66 and 0.84) and U (I ) pound cutoff values for T1WI (82.1 %) and STIR images (79.8 %) were determined from the ROC analyses.T1c and U (I ) pound values provide useful additional information for the differential diagnosis of DC and KCOT.

DOI： 10.1007/s11282-013-0128-2

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Diagnostic value of MR imaging for dentigerous cysts

Hironobu Konouchi, Jun Ichi Asaumi, Yoshinobu Yanagi, Miki Hisatomi, Emiko Saito Arita, Plauto Christopher Aranha Watanabe, Jun Murakami, Teruhisa Unetsubo, Mariko Fujita, Shunsuke Okada, Hidenobu Matsuzaki, Toshihiko Takenobu, Toru Wakasa

Oral Radiology 30 ( 1 ) 13 - 19 2014年1月

記述言語：英語出版者・発行元：SPRINGER

Objectives It is known that the magnetic resonance (MR)imaging features of dentigerous cysts (DCs) are the same as those of other cysts. The cavities of DCs generally show low signal intensity (SI) on T1-weighted imaging (T1WI). However, in our experience, DCs often show high SI on T1WI, rendering them difficult to distinguish from keratocystic odontogenic tumors (KCOTs). In this study, we evaluated seven cases of DC and 23 cases of KCOT to assess whether MR imaging can provide additional information for the differential diagnosis of DC and KCOT. Methods Two trials were evaluated. The first trial was an analysis of the cystic cavity SI on T1WI. To compare the SI between patients, we performed T1WI with contrast (T1c). The second trial analyzed the SI uniformity (UR) on T1WI, T2-weighted imaging (T2WI), and short inversion time inversion recovery (STIR) images of the cystic cavity, because it has been reported that an MR imaging feature of KCOT is heterogeneous SI. Statistical analyses were performed using the Mann-Whitney U test and a receiver operating characteristic (ROC) curve. Results The T1c values of DCs were significantly higher than those for KCOTs. The UR values on T1WI and STIR images were significantly higher for DCs than for KCOTs. The T1c cutoff values (0.66 and 0.84) and UR cutoff values for T1WI (82.1 %) and STIR images (79.8 %) were determined from the ROC analyses. Conclusions T1c and UR values provide useful additional information for the differential diagnosis of DC and KCOT. © Japanese Society for Oral and Maxillofacial Radiology and Springer Japan 2013.

DOI： 10.1007/s11282-013-0128-2

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Fibrous dysplasia of the maxilla: a case report together with its conventional imaging and dynamic magnetic resonance imaging findings

Marina Hara, Hidenobu Matsuzaki, Naoki Katase, Teruhisa Unetsubo, Yoshinobu Yanagi, Hitoshi Nagatsuka, Jun-ichi Asaumi

ORAL RADIOLOGY 30 ( 1 ) 105 - 110 2014年1月

記述言語：英語出版者・発行元：SPRINGER

We previously reported that dynamic contrast-enhanced MRI parameters and time-signal intensity curves (TICs; also known as contrast index curves) are useful for the differential diagnosis of jawbone lesions. In particular, odontogenic fibroma and ossifying fibroma, which possess similar histopathological features (i.e., a mixture of hard and soft tissue components), display unique TIC patterns, and we consider that the TIC patterns of these lesions reflect their hard and soft tissue components. Therefore, fibrous dysplasia, which contains fibrous tissue and immature isolated trabeculae composed of woven bone, is expected to display an interesting TIC. The purpose of this study was to assess the utility of TICs for differentiating between the abovementioned lesions, which have similar histopathological components.

DOI： 10.1007/s11282-013-0137-1

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