Faculty Profiles - NAKATSUKA Mikiya

Papers - NAKATSUKA Mikiya

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Vi．共生社会の実現?性的少数者への支援「生殖・妊娠・子育て・LGBT」関連の技能集団形成プロジェクト

-第6次改訂版-SDGｓの達成に向けた岡山大学の取組事例集 114 - 114 2019.2

Vi．共生社会の実現?性的少数者への支援ＧＡＤ（ジェンダー関連疾患）に対する包括的治療・研究・教育の国内拠点構築

-第6次改訂版-SDGｓの達成に向けた岡山大学の取組事例集 115 - 115 2019.2

Vi．共生社会の実現?性的少数者への支援若年がん患者の生殖機能温存に関するカウンセリングシステムの構築

-第6次改訂版-SDGｓの達成に向けた岡山大学の取組事例集 115 - 115 2019.2

Fertility preservation in adolescent and young adult cancer patients: From a part of a national survey on oncofertility in Japan.

Tatsuro Furui, Yasushi Takai, Fuminori Kimura, Michio Kitajima, Mikiya Nakatsuka, Ken-Ichiro Morishige, Akiko Higuchi, Chikako Shimizu, Miwa Ozawa, Akira Ohara, Ryohei Tatara, Terukazu Nakamura, Keizo Horibe, Nao Suzuki

Reproductive medicine and biology 18 ( 1 ) 97 - 104 2019.1

Language：English Publishing type：Research paper (scientific journal)

Purpose: This study evaluated the current status of reproductive disorders and provision of information on oncofertility to female adolescent and young adult (AYA) cancer patients in Japan. Methods: A national survey of AYA cancer survivors was conducted. Children were <15 years old, and AYAs were 15-39 years old. Results from the survivors of other than gynecological disease who underwent chemotherapy were analyzed. Results: Among the survivors, 41.4% were concerned about their reproductive function and infertility, and 36.2% were aware of menstrual cycle abnormalities. Among them, 15.5% (n = 20) of all and 21.2% (n = 17) of the AYA-onset survivors suffered infertility due to chemo- or radiotherapy and gave up childbearing. These rates were significantly higher than those of healthy AYAs. Although 80.8% of AYA-onset survivors answered that they had received information on reproductive function and infertility, only 55.8% had received information on fertility preservation methods. Furthermore, only 22.4% of all and 42.3% of AYA-onset survivors had received pretreatment information on fertility preservation methods. Conclusions: Not a few AYA cancer survivors reported reproductive dysfunction. These findings indicate that information provided on therapy-related problems before cancer treatment in Japan was insufficient and highlight the need to improve patient decision-making and support systems for fertility preservation.

DOI： 10.1002/rmb2.12256

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性同一性障害（GID）診療を取り巻く最近の状況?専門知識を持っておこうと思う方へ?

日本女性医学学会ニューズレター 24 ( 2 ) 10 - 10 2019.1

Problems of reproductive function in survivors of childhood- and adolescent and young adult-onset cancer revealed in a part of a national survey of Japan.

Reproductive medicine and biology 18 ( 1 ) 105 - 110 2019.1

Language：English Publishing type：Research paper (scientific journal)

Purpose: This study aimed to evaluate the current status of reproductive disorders as long-term complications in adolescent and young adult (AYA) cancer patients by comparing survivors of childhood-onset with those of AYA-onset cancer in Japan. Methods: We conducted a national survey of AYA cancer survivors and healthy AYAs and analyzed the results from survivors who underwent chemotherapy and reported fertility problems as their current concern. Results: Among all of the childhood-onset survivors, 27 (35.5%; nine males [28.1%] and 18 females [40.9%]) listed reproduction fertility problems as their current concern. Among all AYA-onset survivors, 25 (69.5%; 1/4 males [25.0%] and 24/32 females [75.0%]) listed these problems as a current concern. In contrast, 96.3% (26/27) of all childhood-onset cancer survivors and 68.0% (17/25) of all AYA-onset cancer survivors who received chemotherapy listed these problems as a current concern. Conclusions: A considerable number of both childhood-onset and AYA-onset cancer survivors, and especially those who had undergone chemotherapy, reported reproductive dysfunction as a delayed complication. It is vitally important to establish a supportive care system both for the patients whose fertility was abolished after the completion of cancer treatment and prophylactically for patients before they begin treatment.

DOI： 10.1002/rmb2.12255

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妊婦と夫の出生前診断を受けるか否かの話し合いに関する実態調査

美甘祥子, 中塚幹也

日本看護科学学会学術集会講演集 38回 [O15 - 2] 2018.12

性同一性障害当事者における「特別養子縁組」や「生殖医療」により子どもを持つことへの意識

樫野千明, 瀬尾奏衣, 周宇, 新井富士美, 中塚幹也

GID(性同一性障害)学会雑誌 11 ( 1 ) 115 - 128 2018.12

ジェンダークリニックを受診する性同一性障害当事者における戸籍上の性別変更のための手術要件への意識

瀬尾奏衣, 周宇, 樫野千明, 新井富士美, 中塚幹也

GID(性同一性障害)学会雑誌 11 ( 1 ) 129 - 144 2018.12

高校生、大学生におけるLGBTに関する知識と意識

周宇, 南原あかり, 樫野千明, 瀬尾奏衣, 中塚幹也

GID(性同一性障害)学会雑誌 11 ( 1 ) 157 - 167 2018.12

出生前診断を受けるか否かの話し合いに必要な知識の程度に関しての妊婦と夫の比較

美甘祥子, 中塚幹也

母性衛生 59 ( 3 ) 180 - 180 2018.9

岡山県におけるがん生殖医療の取り組みがんと生殖医療ネットワークOKAYAMA

酒本あい, 鎌田泰彦, 増山寿, 羽原俊宏, 林伸旨, 藤井伸治, 枝園忠彦, 中塚幹也

日本がん・生殖医療学会誌 1 ( 1 ) 105 - 105 2018.2

Slow Fetal Heart Rate before Miscarriage in the Early First Trimester Predicts Fetal Aneuploidy in Women with Recurrent Pregnancy Loss.

Ai Sakamoto, Yasuhiko Kamada, Kotaro Kubo, Toru Hasegawa, Sayoko Kotani, Mikiya Nakatsuka, Yuji Hiramatsu

Acta medica Okayama 72 ( 1 ) 61 - 66 2018.2

Language：English Publishing type：Research paper (scientific journal)

Establishing whether miscarriages result from fetal aneuploidy or other factors is important for treating recurrent pregnancy loss. We examined the relationship between fetal heart rate (FHR) before miscarriage in the early first trimester and fetal karyotype, analyzing 223 pregnant women with recurrent pregnancy loss. Among the pregnancies, 110 resulted in live births regarded as normal karyotype (the Norm-group). The other 113 pregnancies ended in miscarriage, and we categorized them into groups based on fetal karyotype, determined by chorionic villus sampling: the Misc-NK (normal karyotype) group, n=35 euploid cases; the Misc-CA1 (chromosomal abnormality) group, n=18 cases of aneuploidy with trisomies 13/18/21, Turner's syndrome, or Klinefelter's syndrome; and the Misc-CA2 subgroup, n=60 cases of other aneuploidies excluding those in the Misc-CA1 group. We compared the groups' regression line slopes and intercepts for FHR by an analysis of covariance. The FHRs of the Norm, Misc-NK and Misc-CA1 groups increased from 36 to 49 days after fertilization, but did not significantly differ across these groups. The Misc-CA2 group's FHR did not increase and significantly differed from the other three groups (p<0.01). These results suggest that the absence of an increase in FHR in early pregnancy may indicate the presence of chromosomal abnormalities causing miscarriage.

DOI： 10.18926/AMO/55664

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大学生における「性同一性障害当事者との関係性の近さ」と理解・支援への意識

大西沙紀, 樫野千明, 北川温子, 藤田志保, 新井富士美, 中塚幹也

GID(性同一性障害)学会雑誌 10 ( 1 ) 25 - 40 2017.12