Faculty Profiles - KUBOKI Takuo

A asessment of the relationship between trapezius muscle pain and skin surface temperature using infrared thermography.

川端秀治, 前川賢治, 窪木拓男, 山下敦, 若狭亨, 岸幹二

岡山歯学会雑誌 18 ( 1 ) 251 - 258 1999

Cold pressor stimulus temperature and resting masseter muscle haemodynamics in normal humans

Kenji Maekawa, Takuo Kuboki, G. T. Clark, Motoki Shinoda, Atsushi Yamashita

Archives of Oral Biology 43 ( 11 ) 849 - 859 1998.11

Language：English Publishing type：Research paper (scientific journal)

Cold pressor stimulation reportedly increases sympathetic nerve activity in human skeletal muscles. This study examined the effect of cold pressor stimulation on the resting haemodynamics of the right masseter muscle in normal individuals, using near-infrared spectroscopy. Nine healthy non- smoking males with no history of chronic muscle pain or vascular headaches participated. Their right hand was immersed in a water bath (4, 10, 15°C) for exactly 1 min. Each trial lasted 7 min (1 min before, 1 min during, 5 min after stimulation) and a strictly random order was utilized for the three test temperatures and the mock trial. Masseter muscle haemoglobin concentration and oxygen saturation, as well as heart rate and blood pressure, were continuously recorded in each trial. After completing the four trials, each participant produced and sustained a 30-s maximum voluntary clench in the intercuspal position. Data across the four trials were baseline-corrected and then magnitude-normalized to the individual's highest absolute haemoglobin and oxygen signal during the 30-s maximal clenching effort. Haemoglobin and oxygen saturation increased progressively during cold pressor stimulation as the water temperature decreased (Hb, p &lt
0.0001
O2, p = 0.0327)
very little effect was seen during the mock trial. Heart rate and blood pressure also increased progressively during the stimulation as the temperature decreased (heart rate, p = 0.0013
systolic blood pressure, p = 0.0042
diastolic blood pressure, p = 0.0156). These data suggest that cold pressor stimulation induces a strong increase in intramuscular blood volume which appears to be due to both a local vasodilative response and increased cardiac output.

DOI： 10.1016/S0003-9969(98)00072-7

Macroscopic osseous changes in the temporomandibular joint related to dental attrition in Japanese macaque skull. Reviewed

Yoshizo Matsuka, T Iijima, K Suzuki, T Kuboki, A Yamashita

Journal of Oral Rehabilitation Vol.25 ( No.9 ) 687 - 693 1998.9

Language：English Publishing type：Research paper (scientific journal)

The purpose of this study was to investigate the relationship between osseous changes in the temporomandibular joint (TMJ) and dental attrition in the Japanese macaque. One hundred and thirty Japanese macaque skulls (54 male and 76 female) from animals which had been bred in the same environment, were randomly sampled from a collection at the Primate Research Institute of Kyoto University. The age at death had been recorded in all cases. TMJ osseous changes were independently evaluated by three examiners, and were defined as an irregular surface or a perforated compact bone layer with a markedly irregular surface on either the temporal or condylar components. Age was a significant factor in predicting TMJ osseous changes (P < 0.001). A strong relation was observed between age and dental attrition (P < 0.001), while dental attrition was not a significant factor in predicting TMJ osseous changes (P = 0.334). The prevalence TMJ osseous changes in male animals was slightly higher than in females (P = 0.057). The results of this study suggest that osseous changes in the macaque TMJ are mainly related to age, not to dental attrition.

The relationship between signs and symptoms of temporomandibular disorders and bilateral occlusal contact patterns during lateral excursions

E. K. Watanabe, H. Yatani, T. Kuboki, Y. Matsuka, S. Terada, M. G. Orsini, A. Yamashita

Journal of Oral Rehabilitation 25 ( 6 ) 409 - 415 1998

Language：English Publishing type：Research paper (scientific journal) Publisher：Blackwell Publishing Ltd

The relationship between signs and symptoms of temporomandibular disorders (TMD) and bilateral occlusal contact patterns was investigated in 143 TMD patients (mean age: 34.0 ± 15.9 years
38 male and 105 female). In addition to an interview regarding chief complaints and accompanying symptoms, various muscles and the temporomandibular joints were palpated bilaterally and occlusal analyses were made. Only 5 out of 108 paired variables were found to be significantly associated by using the chi-squared test. Medial pterygoid muscle pain on palpation showed significant associations with the occlusal contact pattern (P &lt
0.005), especially working side contacts (interocclusal tooth contacts on the working side) (P &lt
0.005), during contralateral excursions
sternocleidomastoid muscle pain on palpation showed a significant association with balancing side contacts (interocclusal tooth contacts on the balancing side) during ipsilateral excursions P &lt
0.05)
shoulder stiffness and pain in the eye showed significant associations with balancing side contacts during contralateral excursions (P &lt
0.05). The results show only a weak relationship between some TMD symptomatology and bilateral occlusal contact patterns during lateral excursions. The findings suggesting the specific laterality of a few TMD signs and symptoms associated with particular occlusal contacts may deserve closer case-control study. © 1998 Blackwell Science Ltd.

DOI： 10.1046/j.1365-2842.1998.00262.x

Diagnostic value of 4 criteria to interpret temporomandibular joint normal disk position on magnetic resonance images

M. Gabriela Orsini, Takuo Kuboki, Shohei Terada, Yoshizo Matsuka, Atsushi Yamashita, Glenn T. Clark

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics 86 ( 4 ) 489 - 497 1998

Language：English Publishing type：Research paper (scientific journal) Publisher：Mosby Inc.

Objective. This study was undertaken to evaluate different criteria to establish normal disk position on magnetic resonance images. Study design. Magnetic resonance image findings of 137 consecutive patients with temporomandibular disorders and 23 asymptomatic volunteers were used in this study. Three calibrated observers interpreted the images individually. Four closed-mouth and 1 open-mouth criteria were tested for their ability to define normal and abnormal temporomandibular joint disk positions on magnetic resonance images. Results. For the 46 joints in the asymptomatic volunteers, the criterion that yielded the highest percentage of normal disk position diagnoses was the disk's intermediate zone (93.5%). Clock face criteria produced the following declining percentages of normal disk position diagnoses: 10 o'clock, 82.6%
11 o'clock, 63.0%
and 12 o'clock, 39.1%. Similar results were obtained for the patients with temporomandibular disorders. In both groups, as the number of normal disk position diagnoses declined, the percentage of joints with a diagnosis of disk displacement with reduction increased. Conversely, the percentage of joints with a diagnosis of disk displacement without reduction (in the group of patients with temporomandibular disorders) did not appear to be substantially affected by the 4 closed-mouth disk position criteria. Conclusions. These results suggest that the intermediate zone criterion for disk displacement is the more stringent criterion and the one that would yield the lowest number of false positives when the disk position is being judged in the closed-mouth sagittal view.

DOI： 10.1016/S1079-2104(98)90380-8

The Validity of clinical examination for diagnosing anterior disk displacement without reduction. (共著)

YATANI H

Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 85 654 - 660 1998

Viscoelastic properties of the pig temporomandibular joint articular soft tissues of the condyle and disc Reviewed

T Kuboki, M Shinoda, MG Orsini, A Yamashita

JOURNAL OF DENTAL RESEARCH 76 ( 11 ) 1760 - 1769 1997.11

Language：English Publishing type：Research paper (scientific journal) Publisher：AMER ASSOC DENTAL RESEARCH

It has been suggested that a sustained loading condition such as clenching could compress the temporomandibular joint (TMJ) articular soft tissues. However, there is still no clear understanding of how the TM joint articular tissues respond under compression. To answer this question, we performed in vitro indentation tests on fresh articular discs and cartilage-bone systems of the condyles of 10 Yorkshire pigs (aged 7 months) using a self-developed indentation tester. The indenter was 5 mm in diameter and was controlled by means of a computer-aided feedback mechanism. Bilateral condyles from the same mandible were uniformly prepared; one was used for measurements under sustained compression (SC) and the other for measurements under intermittent compression (IC). The displacements of the indenter induced by a SC of 10, 20, and 30 Newtons (N, units of force) for 10 min and by an IC, also of 10, 20, and 30 N, with one-second duration and two-second intervals for 10 min were measured by means of a displacement sensor with a resolution of 0.001 mm. From these data, the indentation curves of the articular discs and the cartilage-bone systems were calculated. Both the disc and the articular cartilage showed characteristic displacement vs. time curves-namely, an instantaneous deformation upon load application, followed by a time-dependent creep phase of asymptotically increasing deformation under constant load. However, the indentation curves of the two tissues were not identical: The deformation of the articular cartilage was dose-dependent, but that of the disc was not. Moreover, the articular cartilage deformed significantly less under IC than under SC. This difference was not found in the disc. It can be concluded that both the disc and the articular cartilage of the pig temporomandibular joint have viscoelastic properties against compression; however, the disc is stiffer than the articular cartilage.

Web of Science

ニホンザル顎関節の形態計測学的研究 Reviewed

Yoshizo Matsuka, 飯島輝明, 鈴木康司, 窪木拓男, 矢谷博文, 山下敦, 上月生也, 鈴木秀典

京都大学霊長類研究所年報 Vol.26 81 - 81 1997

Long-term follow-up study on drop-out TMD patients with self-administered questionnaires

Hirofumi Yatani, Takushi Kaneshima, Takuo Kuboki, Akio Yoshimoto, Yoshizo Matsuka, Atsushi Yamashita

Journal of Orofacial Pain 11 ( 3 ) 258 - 269 1997

Language：English Publishing type：Research paper (scientific journal)

Although patient attrition might be a serious threat to the validity of treatment-outcome studies on temporomandibular disorders (TMD), studies on TMD patient attrition are scarce. Of the 1405 consecutive TMD patients examined in a recent 10-year period, 367 (26.1%) drop-out patients or patients identified with a control group were sampled. A mailed questionnaire failed to reach 41 patients, and 203 (62.3%) were returned. The questionnaire elicited information on reasons for dropping out, changes in symptoms, treatment received in other clinics after dropping out, present treatment needs, and current signs and symptoms. Dropouts were divided into two groups: (1) those who failed to show up for their first scheduled appointment after the clinical examination
(2) those who failed to complete treatment. A group of patients who were judged by the examiner not to need treatment were included as a control group. The main reasons for dropping out were environmental obstacles, perceived improvement of the disease, and dissatisfaction with services. Only 21.7% considered themselves to be in need of treatment, and only 10.3% had visited other clinics after dropping out. Only 8.9% complained of the continued aggravation of symptoms, whereas 57.6% reported improvement. In addition, pain, dysfunction, and daily activity limitation tended to improve with time, although temporomandibular joint noise tended to persist. These results suggest that TMD signs and symptoms tend to decrease in patients after dropping out, and that the natural fluctuation of TMD signs and symptoms should be taken into consideration when treating TMD.

The influence of observer calibration in temporomandibular joint magnetic resonance imaging diagnosis

M. Gabriela Orsini, Shohei Terada, Takuo Kuboki, Yoshizo Matsuka, Atsushi Yamashita

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics 84 ( 1 ) 82 - 87 1997

Language：English Publishing type：Research paper (scientific journal) Publisher：Mosby Inc.

Objective. This study was undertaken to investigate the potential of reducing observer variation through a calibration program. Study design. The study was based on three sets of randomly selected temporomandibular joint magnetic resonance images. Each set consisted of bilateral images from 20 consecutive patients with temporomandibular disorders. As a baseline, three well-experienced noncalibrated investigators interpreted the images individually for disk position and disk configuration. After the initial inter-pretation, interobserver agreement was calculated as a kappa index and presented to the examiners. On the same occasion, the investigators analyzed agreement between them on the criteria to be used. Results. Overall data in this study showed an increase in the frequency of interobserver agreement with regard to disk position after the calibration trials were instituted. With regard to disk configuration, substantial interindividual variations were observed even after the observers reached consensus as to the criteria to be used. Conclusions. These data suggest that after calibration trials, it is possible for three examiners to obtain reliable and reproducible results in reporting temporomandibular joint disk position on magnetic resonance images.

DOI： 10.1016/S1079-2104(97)90301-2

The effect of occlusal appliances and clenching on the temporomandibular joint space

Takuo Kuboki, Yoshiharu Azuma, Maria G. Orsini, Tetsuhiko Hirooka, Hirofumi Yatani, Atsushi Yamashita

Journal of Orofacial Pain 11 ( 1 ) 67 - 77 1997

Language：English Publishing type：Research paper (scientific journal)

It has been suggested that stabilization appliances and mandibular anterior repositioning appliances ivork by decompressing the temporomandibular joint. To indirectly test this assumption, tomograms of right temporomandibular joints of seven subjects were taken during comfortable closure and maximum clenching in maximum intercuspation and on the two types of occlusal appliances. Outlines of the condyle and the temporal fossa were automatically determined by an edge detection protocol. Upon comfortable closure, the anterior joint space dimension was reduced with stabilization appliances and mandibular anterior repositioning appliances. Upon maximum clenching, the minimum joint space dimension on stabilization appliances was equivalent to that seen in maximum intercuspation, while that on mandibular anterior repositioning appliances was substantially less (P &lt
.05). Findings do not indicate that these appliances induce an increase in joint space during clenching.

The effect of occlusal appliances and clenching on the temporomandibular joint space

Takuo Kuboki, Yoshiharu Azuma, Maria G. Orsini, Tetsuhiko Hirooka, Hirofumi Yatani, Atsushi Yamashita

Journal of Orofacial Pain 11 ( 1 ) 67 - 77 1997

Language：English Publishing type：Research paper (scientific journal)

Temporomandibular disorders in the adult population of Okayama city, Japan

Yoshizo Matsuka, Hirofumi Yatani, Takuo Kuboki, Atsushi Yamashita

Cranio 14 ( 2 ) 158 - 162 1996

Language：English Publishing type：Research paper (scientific journal) Publisher：Chroma, Inc.

In order to discover the prevalence of signs and symptoms of temporomandibular disorders (TMD) in Japan, and the difference in the prevalence among various sex and age groups in the Japanese population, 672 individuals (304 males and 368 females, age range 20-92 years) were selected randomly in Okayama City, Japan, and were investigated by means of questionnaires and clinical examinations. The reported frequency of symptoms was: TMJ sounds 24%, facial-TMJ-jaw pain 11%, headache 27%, teeth clenching 30%, and grinding 34%. The percent frequency of the following signs was: impaired mouth opening 5%, clicking 46%, reciprocal clicking 20%, crepitus 19%, TMJ tenderness 6%, and masticatory muscle tenderness 21%. The subjects with TMJ clicking were more frequently females than males. TMD signs and symptoms were found to be common in all age groups, but they were fewer in the older than in the younger age group. The younger-aged subjects with clicking appeared with significant frequency, whereas crepitus was populated with significant frequency by the oldest age group. Copyright © 1996 by CHROMA, Inc.

DOI： 10.1080/08869634.1996.11745962

Effects of sustained unilateral molar clenching on the temporomandibular joint space

Takuo Kuboki, Yoshiharu Azuma, Maria G. Orsini, Yasushi Takenami, Atsushi Yamashita

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics 82 ( 6 ) 616 - 624 1996

Language：English Publishing type：Research paper (scientific journal) Publisher：Mosby Inc.

Objective. To measure the effect of unilateral sustained clenching on the temporomandibular joints, changes in the minimum joint space dimension were assessed. Study design. Ten healthy subjects performed a sustained clench on a bite force transducer in the first molar region for 5 minutes with a constant force of 170 N. Three separate sagittal tomograms were bilaterally obtained with the transducer in place before clenching and during the beginning and at the end of the contraction. Changes were quantified with a computerized image analysis system. Results. The minimum joint space of the contralateral temporomandibular joint was significantly reduced both at the beginning and at the end of the contraction task. Further the minimum joint space was also significantly less at the end than at the beginning of the contraction even though bite force level was identical. The ipsilateral condyle images showed no significant shift in the minimum joint space. Conclusions. These data suggest that unilateral molar clenching induces a significant reduction of the minimum joint soace in the contralateral temooromandibular joint and a sustained condition remarkably increases this change. Copyright © 1996 by Mosby-Year Book, Inc.

DOI： 10.1016/S1079-2104(96)80435-5

Effects of sustained unilateral molar clenching on the temporomandibular joint space

Takuo Kuboki, Yoshiharu Azuma, Maria G. Orsini, Yasushi Takenami, Atsushi Yamashita

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics 82 ( 6 ) 616 - 624 1996

Language：English Publishing type：Research paper (scientific journal) Publisher：Mosby Inc.

DOI： 10.1016/S1079-2104(96)80435-5