Faculty Profiles - MAKINO Takuma

Papers - MAKINO Takuma

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Young adult patients with squamous cell carcinoma of the tongue strongly express p16 without human papillomavirus infection. Reviewed International journal

Tachibana T, Orita Y, Gion Y, Miki K, Ikegami K, Marunaka H, Makino T, Akagi Y, Akisada N, Tsumura M, Ito T, Yoshino T, Nishizaki K, Sato Y

Acta oto-laryngologica 139 ( 1 ) 80 - 84 2019.1

Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: Long-term smoking and drinking are known to contribute to the onset of tongue cancer (TC). However, the increasing incidence of TC in younger adults has been suggested to be associated with other factors. OBJECTIVES: The present study investigated the relationship between TC and human papillomavirus (HPV) infection. MATERIAL AND METHODS: Clinical records and surgically resected specimens from 86 patients (<40-years-old, n = 12; ≥40-years-old, n = 74) with TC were analyzed. Strong nuclear and cytoplasmic p16 staining was considered positive. HPV DNA (high-risk subtypes: 16, 18, 31, 33, 35, 52b, and 58; low-risk subtypes: 6 and 11) was detected using consensus primer-mediated polymerase chain reaction. RESULTS: Strong p16 expression was observed in 10 (11.6%) patients. HPV DNA was detected in 9 (10.5%) patients (high-risk subtypes, n = 2; low-risk subtypes, n = 7). Strong p16 expression was observed more frequently among younger adults than among older adults (33.3% vs. 8.1%; p = .045). p16 staining did not correlate with the detection of HPV DNA (correlation coefficient, 0.113; p = .300). CONCLUSIONS AND SIGNIFICANCE: In TC, p16 expression was not associated with HPV infection, suggesting that it may be caused by a different mechanism.

DOI： 10.1080/00016489.2018.1541506

PubMed

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Factors that prolong the duration of recovery in acute rhinosinusitis with orbital complications. Reviewed

Tachibana T, Kariya S, Orita Y, Nakada M, Makino T, Haruna T, Matsuyama Y, Komatsubara Y, Naoi Y, Sato Y, Nishizaki K

Acta Otolaryngol 10 1 - 5 2019

Factors that prolong the duration of recovery in acute rhinosinusitis with orbital complications. Reviewed International journal

Tomoyasu Tachibana, Shin Kariya, Yorihisa Orita, Michihiro Nakada, Takuma Makino, Takenori Haruna, Yuko Matsuyama, Yasutoshi Komatsubara, Yuto Naoi, Yasuharu Sato, Kazunori Nishizaki

Acta oto-laryngologica 139 ( 1 ) 52 - 56 2019

Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: Regarding prognostic factors of acute rhinosinusitis (ARS) with orbital complications, there are few studies including adult cases. OBJECTIVES: The present study aims to delineate prognostic factors of ARS with orbital complications. MATERIAL AND METHODS: We conducted a retrospective analysis of medical records of 21 patients (6 pediatric and 15 adult patients) with ARS with orbital complications. The duration of recovery was defined as the time from initial diagnosis to complete resolution of local findings and all symptoms. Orbital complications due to postoperative cysts or mycosis were excluded. RESULTS: Twenty-one patients comprised 11 males and 10 females. Chandler's classification showed group I in 4, group II in 8, and group III in 9. None of six pediatric patients required any surgical intervention, whereas five adult patients (23.8%) underwent surgical intervention. The average period of recovery was 8.1 days. In univariate analysis, the duration of recovery was significantly longer among adult cases (p < .01) and cases with Chandler's groups II-III (p = .019). In multivariate analysis, adult patients had a significantly longer duration of recovery than pediatric patients (p = .027). CONCLUSION AND SIGNIFICANCE: The present study suggested that ARS with orbital complications may have prolonged clinical course in adults.

DOI： 10.1080/00016489.2018.1539516

PubMed

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Computed Tomography Findings for Diagnosing Follicular Thyroid Neoplasms. Reviewed

Makino T, Orita Y, Tachibana T, Marunaka H, Miki K, Akisada N, Akagi Y, Usui Y, Sato Y, Yoshino T, Nishizaki K

Acta medica Okayama 72 ( 6 ) 577 - 581 2018.12

Canal wall-down procedure with soft posterior meatal wall reconstruction in acquired cholesteatoma: focus on postoperative middle ear status* Reviewed International journal

Tomoyasu Tachibana, Shin Kariya, Yorihisa Orita, Michihiro Nakada, Takuma Makino, Yasutoshi Komatsubara, Yuko Matsuyama, Yuto Naoi, Kazunori Nishizaki

Acta Oto-Laryngologica 138 ( 8 ) 695 - 700 2018.8

Prognostic factors and importance of recognition of adult croup Reviewed International journal

Tomoyasu Tachibana, Yorihisa Orita, Takuma Makino, Yasutoshi Komatsubara, Yuko Matsuyama, Yuto Naoi, Michihiro Nakada, Yasuharu Sato, Kazunori Nishizaki

Acta Oto-Laryngologica 138 ( 6 ) 579 - 583 2018.6

Neck metastasis in patients with T1-2 supraglottic cancer Reviewed International journal

Tomoyasu Tachibana, Yorihisa Orita, Hidenori Marunaka, Sei-ichiro Makihara, Misato Hirai, Yuka Gion, Kana Ikegami, Kentaro Miki, Takuma Makino, Yasuyuki Noyama, Yasutoshi Komatsubara, Miyuki Kimura, Tadashi Yoshino, Kazunori Nishizaki, Yasuharu Sato

Auris Nasus Larynx 45 ( 3 ) 540 - 545 2018.6

Squamous cell carcinoma of the bilateral external auditory canals Reviewed

Shin Kariya, Yohei Noda, Munechika Tsumura, Takuma Makino, Hidenori Marunaka, Kazunori Nishizaki

Otolaryngology - Head and Neck Surgery (Japan) 90 ( 7 ) 577 - 582 2018.6

耳後部有茎皮弁にて外耳道再建した両側性外耳道扁平上皮癌の1例 Reviewed

假谷伸, 野田洋平, 津村宗近, 牧野琢丸, 丸中秀格, 西崎和則

耳鼻咽喉科・頭頸部外科 90 ( 7 ) 577 - 582 2018.6

椎周囲間隙に発生した頸部筋間脂肪腫例 Reviewed

牧野琢丸, 橘智靖, 小松原靖聡

耳鼻咽喉科臨床 111 ( 6 ) 395 - 399 2018.6

Laryngeal squamous cell papilloma is highly associated with human papillomavirus Reviewed International journal

Yorihisa Orita, Yuka Gion, Tomoyasu Tachibana, Kana Ikegami, Hidenori Marunaka, Seiichiro Makihara, Yasuhiko Yamashita, Kentaro Miki, Takuma Makino, Naoki Akisada, Yusuke Akagi, Miyuki Kimura, Tadashi Yoshino, Kazunori Nishizaki, Yasuharu Sato

Japanese Journal of Clinical Oncology 48 ( 4 ) 350 - 355 2018.4

A case of intermuscular lipoma in the perivertebral space Reviewed

Takuma Makino, Tomoyasu Tachibana, Yasutoshi Komatsubara

Practica Oto-Rhino-Laryngologica 111 ( 6 ) 395 - 399 2018

A case of a fish bone in the neck removed using CT- guided hookwire placement Reviewed

Yasutoshi Komatsubara, Tomoyasu Tachibana, Takuma Makino, Yuto Naoi, Aiko Shimizu, Mayu Uga, Akihito Mitsumori

Otolaryngology - Head and Neck Surgery (Japan) 89 ( 10 ) 849 - 853 2017.9

CTガイド下マーキングが有用であった頸部魚骨異物例 Reviewed

小松原靖聡, 橘智靖, 牧野琢丸, 直井勇人, 清水藍子, 宇賀麻由, 三森天人

耳鼻咽喉科・頭頸部外科 89 ( 10 ) 849 - 853 2017.9

Sphenoid sinusitis with trismus in a child Reviewed

Yyto Naoi, Tomoyasu Tachibana, Takuma Makino, Yasutoshi Komatsubara, Akihito Mitsumori

Otolaryngology - Head and Neck Surgery (Japan) 89 ( 6 ) 465 - 470 2017.5

開口障害を伴った小児蝶形骨洞炎例 Reviewed

直井勇人, 橘智靖, 牧野琢丸, 小松原靖聡, 三森天人

耳鼻咽喉科・頭頸部外科 89 ( 6 ) 465 - 469 2017.5

気管憩室を併存した甲状腺乳頭癌例 Reviewed

橘智靖, 折田頼尚, 牧野琢丸, 小松原靖聡, 西崎和則

日本内分泌・甲状腺外科学会雑誌 34 ( 1 ) 65 - 69 2017.3

Tumor-Associated Macrophages in the Development of 4-Nitroquinoline-1-Oxide-Induced Tongue Squamous Cell Carcinoma in a Mouse Model Reviewed International journal

Kentaro Miki, Yorihisa Orita, Yuka Gion, Soshi Takao, Kyotaro Ohno, Mai Takeuchi, Toshihiro Ito, Akira Minoura, Tomoyasu Tachibana, Hidenori Marunaka, Takuma Makino, Akihiro Matsukawa, Kazunori Nishizaki, Tadashi Yoshino, Yasuharu Sato

ONCOLOGY 93 ( 3 ) 204 - 212 2017

A case of herpetic tonsillitis showing tumor-like lesion Reviewed

Aiko Shimizu, Tomoyasu Tachibana, Takuma Makino, Yuko Matsuyama, Yasutoshi Komatsubara, Yoji Wani, Tami Nagatani

Otolaryngology - Head and Neck Surgery (Japan) 88 ( 13 ) 1053 - 1056 2016.12

腫瘍様所見を呈した単純ヘルペスウイルスによる扁桃炎例 Reviewed

清水藍子, 橘智靖, 牧野琢丸, 松山祐子, 小松原靖聡, 和仁洋治, 永谷たみ

耳鼻咽喉科・頭頸部外科 88 ( 13 ) 1053 - 1056 2016.12

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Papers - MAKINO Takuma