研究者詳細 - 片岡　祐子

その他リンク： http://search.jamas.or.jp/link/ui/2007099016

Using assessment of higher brain functions of children with GJB2-associated deafness and cochlear implants as a procedure to evaluate language development 査読

Akihiro Kawasaki, Kunihiro Fukushima, Yuko Kataoka, Shoichiro Fukuda, Kazunori Nishizaki

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY 70 ( 8 ) 1343 - 1349 2006年8月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：ELSEVIER IRELAND LTD

Objective: While investigators have reported that patients with GJB2-associated deafness and cochlear implants have preferable language development, the mechanisms of this phenomenon remains unknown. The goat of the present study was to assess higher brain functions of patients with GJB2-retated and GJB2-unrelated deafness as a method of evaluating language development.
Methods: Eight children with cochlear implants were subjected to genetic testing for GJB2 and underwent the Raven colored progressive matrices test, Rey's auditory verbal learning test, Rey's complex figure test, the standardized Language test for aphasia, the picture vocabulary test, and the standardized comprehension test for abstract words.
Results: Three children were diagnosed with GJB2-related deafness, and five children were diagnosed with GJB2-unrelated deafness. All three GJB2-related cases demonstrated normal range higher brain functions and fair language development. By contrast, one GJB2-unrelated case showed a semantic disorder, another demonstrated a visual cognitive disorder with dyslexia, and another had attention deficit-hyperactivity disorder.
Conclusions: Children with GJB2-unrelated deafness showed a high frequency of heterogeneous disorders that can affect proper language development. This difference between children with GJB2-retated and GJB2-unrelated deafness may account for the improved language development in children with GJB2-related deafness and cochlear implants. Further, genetic diagnosis of the non-syndromic hearing toss represents a useful tool for the preoperative prediction of outcomes following a cochlear implant procedure. (C) 2006 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.ijporl.2006.01.010

Web of Science

PubMed

前庭・蝸牛周囲の緻密骨中に骨透亮像を呈した混合難聴合併exomphalosmacroglossia-gigantism (EMG)症候群の1例

福山祐子, 福島邦博, 片岡祐子, 假谷伸, 西崎和則

耳鼻と臨床 52 ( 6 ) 338 - 341 2006年

記述言語：日本語出版者・発行元：耳鼻と臨床会

Beckwith-Wiedemann症候群は脇ヘルニア (exomphalos) 、巨舌 (macroglossia) 、巨人症 (gigantism) を三主徴とする遺伝性疾患であり (以下EMG症候群) 、まれに伝音難聴を伴うことが報告されている。今回、EMG症候群に合併した混合性難聴の1例を経験したので報告する。症例は9歳女児、軽度の難聴を指摘され、当院紹介となった。純音聴力検査の結果では両側の軽度混合性難聴を認め、画像所見では前庭・蝸牛周囲の緻密骨中に骨透亮像を認めた。既報では、手術時にアブミ骨固着による難聴であることが確認されているが、EMG症候群の側頭骨画像は、今回はじめて報告する。これらの所見からも、本症例は耳硬化症と類似する病態が存在すると考えられた。

DOI： 10.11334/jibi1954.52.6_338

その他リンク： http://search.jamas.or.jp/link/ui/2007108867

人工内耳装用による語音明瞭度改善例の異聴傾向

福田章一郎, 問田直美, 福島邦博, 片岡祐子, 西崎和則

AUDIOLOGY JAPAN 49 ( 6 ) 798 - 802 2006年

記述言語：日本語出版者・発行元：Japan Audiological Society

人工内耳埋め込み後, 語音明瞭度の改善が顕著であった先天性感音難聴児9例の異聴傾向を検討した。人工内耳装用後, 適切なマッピングによる聴覚学習と療育を受けた結果, 57語表による語音検査で9症例の平均は85.1%となり非常に高い明瞭度が得られた。人工内耳装用児の異聴傾向は有声破裂音を除き難聴者とほぼ同じ傾向を示した。無声子音の明瞭度は有声子音に比し高かった。特に, 摩擦音の明瞭度が高かったがこれは人工内耳の場合は補聴器と比較し, 高い周波数まで聴取可能であるため明瞭度の向上が得られたことによると考えられる。人工内耳の語音聴取の改善には周波数分解能と同時に時間分解能が関与していることが示唆され, 個々の異聴傾向はそれぞれの複雑な組み合わせによるものと考えられる。しかしながら, 摩擦音, 破擦音では構音点が後方であるほど明瞭度が低下する傾向がみられ, 今後の検討課題である。

DOI： 10.4295/audiology.49.798

新生児難聴スクリーニングとその後の対応新生児聴覚スクリーニングから精密聴力検査へ

福島邦博, 片岡裕子, 西崎和則

AUDIOLOGY JAPAN 49 ( 3 ) 227 - 232 2006年

記述言語：日本語出版者・発行元：Japan Audiological Society

新生児聴覚スクリーニングでは, 母子の愛着形成の前に行われる難聴の告知が母親の不安を増幅し, これがスクリーニングを行うことの問題点であると考えられてきた。我々は, 岡山県聴覚検査事業の中で行われている保健師による訪問指導調査票を精査し, その結果をレトロスペクティブに解析した。訪問指導では, 母親の不安や心配に関する質問が行われ, 聴覚スクリーニング後の精密検査の有無が確認されていた。調査期間の間, 47346人のスクリーニングが行われ, そのうち248人がリファーと診断された。その中では171人の調査報告書が岡山県に報告されていた。この171人中では, 39人は不安を訴えたが, 39人中19人は合併する障害があり, 心配の中心はその他のより重篤な障害であった。16例は訪問指導の時点では診断ないしは受容の途上であり, 4例の片側例でのみ予想外の不安が見られた。育児放棄は多発奇形の一例に見られた。聴覚スクリーニング後の不安の頻度は一般の産後の不安と変わらないが, 日本における新生児聴覚スクリーニングの成功のためには, 不安や心配を最小限にする努力が必要である。

DOI： 10.4295/audiology.49.227

聴性定常反応検査の周波数別聴力:標準純音聴力検査との比較:-BIS値を指標とした覚醒度の与える影響- 査読

川崎聡大, 福島邦博, 片岡祐子, 市川智継, 中塚秀樹, 西崎和則

耳鼻と臨床 52 ( 1 ) 33 - 37 2006年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：JIBI TO RINSHO KAI

聴性定常反応検査 (auditory steady stateresponse:以下ASSRと略す) は、周波数特異的な聴性反応が得られる聴力像の推定が可能な新しい他覚的聴力検査法の一つとして期待される。今回われわれはトロント大学方式を採用した高変調周波数を用いた NavigaterPro (解析ソフトウェアMASTERTM) を用いて標準純音聴力検査とASSR閾値との相関について検討した。さらにBispectral Index (以下BIS値とする) を指標として覚醒度が与えるASSR結果への影響について検討を加えた。結果、1) 標準純音聴力検査との間に一定の相関を認めたこと、2) 覚醒度が高い場合に結果の信頼性に問題があること、3) BIS値の低下した症例では比較的困難とされる低い音圧での閾値の推定が可能であったことが判明し、覚醒状態の与えるASSR閾値への影響について知見を得ることができた。

DOI： 10.11334/jibi1954.52.1_33

軽度難聴児の言語発達に与える高次脳機能 : 神経心理学的評価に基づく認知特性の検討査読

川崎聡大, 杉下周平, 福島邦博, 片岡祐子, 長安吏江, 市川智継, 西崎和則

小児耳鼻咽喉科 26 ( 2 ) 51 - 55 2005年12月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Japan Society for Pediatric Otorhinolaryngology

Learning disability is the single most frequent complication of hearing impairment, occurring in up to 15% of all school-aged deaf children. Neuropsychological evaluations of these cases may contribute to further diagnosis of the additional handicaps and the identification of a suitable procedure for better intervention. A nine-year-old boy with mild hearing impairment was referred to our hospital because of his poor language development. His average pure tone audiometry was 35dBnHL in the right ear and 65 dBnHL in the left ear and audiological interventions with a hearing aid had already been started before the referral to our clinic. Although mild mental retardation was suggested by WISC-III, as FIQ65 (VIQ 65, VIQ71, and PIQ65), non-verbal intelligence examined by RCPM corresponded to the normal range. Verbal and non-verbal semantic disorder was considered by the results from ScTaw and SLTA. He was later diagnosed as having Asperger syndrome and his semantic problem concomitant with Asperger syndrome could be another cause of his additional language delay.

DOI： 10.11374/shonijibi1980.26.2_51

認知能力の個人内差が人工内耳装用後の言語発達に及ぼした影響

川崎聡大, 福島邦博, 福本裕子, 長安吏江, 国末和也, 片岡裕子, 西崎和則

小児耳鼻咽喉科 25 ( 2 ) 46 - 50 2004年12月

記述言語：日本語出版者・発行元：日本小児耳鼻咽喉科学会

A considerable number of prelingually-deafened children with cochlear implants demonstrated discrepancies between their speech perception ability and language development. The difference may be caused partly by the intrapersonal discrepancies among cognitive functions, including visual and auditory cognitive functions. Different clinical outcomes were observed among 3 prelingual deafness cases with cochlear implants and the profiles of their language development and neuropsychological tests were reported here. One case (MW) demonstrated the proper syntactic strategy corresponding to her hearing peers and neuropsychological evaluations revealed that her cognitive functions were well balanced. Two other cases (SN and YH) demonstrated considerable delay in the syntactic strategy for their communication and visual cues were needed to accomplish the interventional goal. It was assumed that the auditory memories of these two cases were affected. Although their medical and educational backgrounds were highly similar, the first outcome and the consequent procedures for intervention were different. Neuropsychological tests can provide crucial information for the optimum interventional approach for implant users.

DOI： 10.11374/shonijibi1980.25.2_46

その他リンク： http://search.jamas.or.jp/link/ui/2005089882

Monosyllable speech perception of Japanese hearing aid users with prelingual hearing loss: Implications for surgical indication of cochlear implant

Shoichiro Fukuda, Kunihiro Fukushima, Naomi Toida, Keiko Tsukamura, Yukihide Maeda, Namiki Kibayashi, Rie Nagayasu, Yorihisa Orita, Norio Kasai, Yuko Kataoka, Kazunori Nishizaki

International Journal of Pediatric Otorhinolaryngology 67 ( 10 ) 1061 - 1067 2003年10月

掲載種別：研究論文（学術雑誌）

Objective: The monosyllable speech perception ability after years of educational intervention was compared between prelingually deafened pediatric hearing aid users and their cochlear implant counterparts. Design: An open-set monosyllabic speech perception test was conducted on all subjects. The test required subjects to indicate a corresponding Japanese character to that spoken by the examiner. Fifty-two subjects with prelingual hearing impairment (47 hearing aid users and 5 cochlear implant users) were examined. Results: Hearing aid users with average pure-tone thresholds less than 90 dB HL demonstrated generally better monosyllable perception than 70%, which was equivalent or better performance than that of the cochlear implant group. Widely dispersed speech perception was observed within the 90-99 dB HL hearing-aid user group with most subjects demonstrating less than 50% speech perception. In the cluster of > 100 dB HL, few cases demonstrated more than 50% in speech perception. The perception ability of the vowel part of each mora within the cochlear implant group was 100% and corresponding to that of hearing aid users with moderate and severe hearing loss. Conclusion: Hearing ability among cochlear implant users can be comparable with that of hearing aid users with average unaided pure-tone thresholds of 90 dB HL, after monosyllabic speech perception testing was performed. © 2003 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/S0165-5876(03)00187-3

Scopus

PubMed

Meniere's disease in childhood 査読

Hirofumi Akagi, Koji Yuen, Yukihide Maeda, Kunihiro Fukushima, Shin Kariya, Yorihisa Orita, Yuko Kataoka, Teruhiro Ogawa, Kazunori Nishizaki

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY 61 ( 3 ) 259 - 264 2001年12月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：ELSEVIER SCI IRELAND LTD

We report 3 rare cases of Meniere's disease in children. In Case I and 3, vertigo, hearing loss and tinnitus recovered soon after medical therapy. In Case 2. however, vertigo recurred and the hearing level on the right side markedly deteriorated. The equal-loudness contours on three-dimensional audiogram showed that right-sided aggravated hearing loss fluctuated for 4 years at middle-and low-frequencies despite medication. Finally intratympanic injection of gentamicin sulfate was performed. The patient has had no definitive spell of vertigo after gentamicin therapy. At our department, the incidence of Meniere's disease in pediatric patients with vertigo was 2.9%. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

Web of Science

頸部リンパ節腫脹で発症した顆粒球肉腫例

片岡祐子, 赤木博文, 木村宣彦, 中島智子, 小川晃弘, 西崎和則

耳鼻咽喉科臨床 94 ( 7 ) 645 - 648 2001年7月

記述言語：日本語出版者・発行元：The Society of Practical Otolaryngology

Granulocytic sarcoma was first described by Burns in 1811 and it is known to be an extramedullary tumor composed of immature precursor cells. It sometimes occurs with acute myeloid leukemia or myeloproliferative disorders, but there have been reports of cases occurring without such hematological disorders. A 40-year-old female with a chief complaint of neck swelling was examined in our department in 1997. CT scan showed bilateral neck lymph nodes swelling. Histological examination of open biopsy confirmed myeloblastic-type tumor cells, but peripheral blood and bone marrow examination showed no evidence of leukemia. The final diagnosis of this case was granulocytic sarcoma without hematological disorder.

DOI： 10.5631/jibirin.94.645