Faculty Profiles - TAKAKI Manabu

MISC - TAKAKI Manabu

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音響--明瞭度と音楽性…室内の多彩な環境を演出—これが二大ドームの全容だ!! ; 大阪ドーム

高木学

月刊体育施設 : スポーツ施設&マネジメント情報誌 / 体育施設出版編 ; 日本体育施設協会監修 26 ( 7 ) 29 - 31 1997.5

ENVIRONMENTAL AND IMMUNOLOGICAL SURVEY OF SENSITIZATION WITH JAPANESE CEDAR (CRYOTOMERIA JAPONICA) POLLEN IN CHILDREN : Part 2 The Clinical Significance of Japanese Cedar (Cryptomeria japonica) Pollen Specific IgE Antibody and IgG4 Antibody

Takagi Manabu

Japanese Journal of Allergology 41 ( 11 ) 1540 - 1546 1992

Language：Japanese Publisher：Japanese Society of Allergology

The clinical manifestations and Japanese cedar (sugi in Japanese) pollen specific antibodies were studied in 340 children who had not received specific hyposensitization. Specific IgE antibodies were measured by radioallergosorbent test (RAST) and IgG4 antibody by enzyme linked immunosorbent assay (ELISA). There were 52 children (15%) with RAST scores of over 2, and 44 children (13%) with ELISA of over 101 mu/ml. The specific IgG4 level was significantly higher in the RAST positive group than in the negative group. The incidence of pollinosis among children with RAST negative and IgG4 below 100 mu/ml was 13.3%, while combinations of RAST negative and higher ELISA, RAST positive and low ELISA, and RAST positive and higher ELISA were 50.0%〜62.5%. There were 5 children with RAST scores of 4, and 6 children with ELISA of over 201 mu/ml. Symptoms of pollinosis manifested in all of them. Since the children with low IgE and high IgG4 antibodies had comparatively more symptoms, the IgG4 antibodies might be reaginic. It was concluded that measurement of sugi specific IgG4 antibodies as well as IgE antibodies could provide useful data on pollinosis in children.

DOI： 10.15036/arerugi.41.1540

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ENVIRONMENTAL AND IMMUNOLOGICAL SURVEY OF SENSITIZATION WITH JAPANESE CEDAR (CRVPTOMERIA JAPONICA) POLLEN IN CHILDREN : Part 1 Environmental Factors Influencing Sensitization with Japanese Cedar (Cryptomeria japonica) Pollen Among Asthmatic Children

Takagi Manabu

Japanese Journal of Allergology 37 ( 11 ) 1065 - 1071 1988

Language：Japanese Publisher：Japanese Society of Allergology

The incidence of positive skin test to the Japanese cedar(sugi in Japanese) pollen increase among children for the last decade. In order to find out the reason for the increase, we compared the size of sugi forest, the pollen counts, number of automobiles and the incidence of positive skin test of sugi in the 4 hospitals in Saitama prefecture. The hospital in the west locates in the largest sugi forest with the highest pollen count, and it showed the same incidende of positive skin test to sugi pollen to 3 hospotals where they had smoller sugi forest, lower pollen count and more number of automobiles. And the positive test started at 3 years of age and reached to the peak at 10 to 12 years of age. It is suggested that the sensitization with the pollen count as well as air pollution such as automobile exhaust and the sensitization may have started earlier along with environmental change.

DOI： 10.15036/arerugi.37.1065

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