研究者詳細 - 萩谷　英大

論文 - 萩谷　英大

分割表示 441 件中 301 - 320 件目／全件表示 >>

Antibiotic-associated adverse drug events at a Japanese academic hospital. 査読国際誌

Kokado R, Hagiya H, Koyama T, Matsui E, Okuno H, Morii D, Hamaguchi S, Yoshida H, Miwa Y, Tomono K

J Infect Chemother 25 ( 5 ) 392 - 395 2019年5月

Association between rapid antigen detection tests and antibiotics for acute pharyngitis in Japan: A retrospective observational study. 査読国際誌

Yusuke Teratani, Hideharu Hagiya, Toshihiro Koyama, Ayako Ohshima, Yoshito Zamami, Yasuhisa Tatebe, Ken Tasaka, Kazuaki Shinomiya, Yoshihisa Kitamura, Toshiaki Sendo, Shiro Hinotsu, Mitsunobu R Kano

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 25 ( 4 ) 267 - 272 2019年4月

記述言語：英語掲載種別：研究論文（学術雑誌）

The application and clinical impact of rapid antigen detection test (RADT) in the treatment of acute pharyngitis is unknown in Japan. We aimed to examine the proportions of RADT usage to identify Group A β-hemolytic Streptococcus (GAS) in outpatients with acute pharyngitis and evaluate the association between RADT and antibiotic treatment. We analyzed health insurance claims data from 2013 to 2015. Logistic regression models were used to analyze associated factors with RADT, overall antibiotic prescription, or penicillin use. We analyzed 1.27 million outpatient visits with acute pharyngitis, in which antibiotics were prescribed in 59.3% of visits. Of the total visits, 5.6% of patients received RADT, and 10.8% of the antibiotics were penicillin. Penicillin selection rates were higher in cases with RADT (25.4%) than those without RADT (9.7%). Compared to large-scale facilities, antibiotic prescription rates were higher in physicians' offices. For factor analysis, age (3-15 years), diagnosis code (streptococcal pharyngitis), size of the medical facility (large-scale hospitals), and physician's specialty (pediatrics) were associated with RADT use. Penicillin selection rate increased with RADT implementation (25.4% vs. 9.7%: adjusted odds ratio 1.55; 95% CI, 1.50-1.60). At 63% of the facilities, the RADT implementation rate was <5% of acute pharyngitis visits prescribed antibiotics. In conclusion, the proportion of RADT usage for outpatients with acute pharyngitis was low in Japan. With appropriate indication and evaluation, we expect that more utilization of RADT can help promote antimicrobial stewardship for outpatients with acute pharyngitis by prompting penicillin therapy. Further investigation with detailed clinical data are warranted.

DOI： 10.1016/j.jiac.2018.12.005

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Repeated Left Upper Abdominal Pain. 査読

Kazuhiro Hongyo, Futoshi Nakagami, Hideharu Hagiya, Hiromi Rakugi

Internal medicine (Tokyo, Japan) 58 ( 6 ) 893 - 893 2019年3月

Fastidious spiral bacilli causing backbone infections after gastroenteritis. 国際誌

Koichiro Lee, Hideharu Hagiya, Misaki Kageyama, Futoshi Nakagami

BMJ case reports 12 ( 3 ) 2019年3月

Spreading Patterns of NDM-Producing Enterobacteriaceae in Clinical and Environmental Settings in Yangon, Myanmar. 査読国際誌

Sugawara Y, Akeda Y, Hagiya H, Sakamoto N, Takeuchi D, Shanmugakani RK, Motooka D, Nishi I, Zin KN, Aye MM, Myint T, Tomono K, Hamada S

Antimicrobial agents and chemotherapy 63 ( 3 ) 2019年3月

Mycobacterium avium complex infection mimicking lung cancer. 国際誌

Hideharu Hagiya

BMJ case reports 12 ( 2 ) 2019年2月

PCR-Dipstick-Oriented Surveillance and Characterization of mcr-1- and Carbapenemase-Carrying Enterobacteriaceae in a Thai Hospital. 査読国際誌

Shanmugakani RK, Akeda Y, Sugawara Y, Laolerd W, Chaihongsa N, Sirichot S, Yamamoto N, Hagiya H, Morii D, Fujiya Y, Nishi I, Yoshida H, Takeuchi D, Sakamoto N, Malathum K, Santanirand P, Tomono K, Hamada S

Frontiers in microbiology 10 149 - 149 2019年2月

An uncommon cause of leg oedema. 査読国際誌

Naito T, Hagiya H, Nakagami F, Yamamoto K

BMJ case reports 12 ( 1 ) 2019年1月

Acute Non-calcific Retropharyngeal Tendinitis. 査読

Futoshi Nakagami, Hideharu Hagiya, Hiromi Rakugi

Internal medicine (Tokyo, Japan) 57 ( 23 ) 3499 - 3500 2018年12月

Persistent methicillin-resistant Staphylococcus aureus bacteremia owing to placental abscess. 査読国際誌

Naomi Maeda, Hideharu Hagiya, Tsuyoshi Takiuchi, Shinsuke Kusakabe, Tetsuo Maeda, Keigo Kimura, Sayuri Iwai, Keisuke Kawasaki, Yumiko Hori, Eiichi Morii, Yuzuru Kanakura, Tadashi Kimura, Kazunori Tomono

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 24 ( 12 ) 975 - 979 2018年12月

記述言語：英語掲載種別：研究論文（学術雑誌）

Staphylococcus aureus as a pathogen in human gestational membranes, a rather rare phenomenon, has recently been the focus of several researches. S. aureus forms biofilms on these membranes and potentially causes chorioamnionitis in pregnant women. We report a case of persistent methicillin-resistant S. aureus (MRSA) bacteremia owing to placental infection, causing chorioamnionitis and preterm birth. A 29-year-old Japanese woman at the 27th gestational week was diagnosed with acute promyelocytic leukemia and underwent all-trans retinoic acid therapy. Soon after hospitalization, the patient presented with persistent MRSA bacteremia of unknown origin. Despite various antimicrobial therapies, she experienced 12 MRSA bacteremia episodes over 6 weeks. However, after child birth, MRSA bacteremia disappeared without any complications. A pathologic examination of her placenta revealed placenta abscess, resulting in a diagnosis of MRSA-associated chorioamnionitis. Molecular analysis proved that a single MRSA strain (SCCmec Type IVa), which tested negative for Panton-Valentine leukocidin and toxic shock syndrome toxin-1, caused the obstinate infection. We should be aware that persistent MRSA bacteremia in pregnant women can originate from placental abscess.

DOI： 10.1016/j.jiac.2018.05.001

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Swollen Extraocular Muscle and Tingling Extremities. 査読国際誌

Futoshi Nakagami, Hideharu Hagiya, Akane Oyama, Kazuhiro Hongyo, Motonori Nagasawa, Hiromi Rakugi

The American journal of medicine 131 ( 12 ) e492-e493 2018年12月

Trends in Polypharmacy in Japan: A Nationwide Retrospective Study. 査読国際誌

Hiroshi Onoue, Toshihiro Koyama, Yoshito Zamami, Hideharu Hagiya, Yasuhisa Tatebe, Naoko Mikami, Kazuaki Shinomiya, Yoshihisa Kitamura, Shiro Hinotsu, Toshiaki Sendo, Yasuyoshi Ouchi, Mitsunobu R Kano

Journal of the American Geriatrics Society 66 ( 12 ) 2267 - 2273 2018年12月

記述言語：英語掲載種別：研究論文（学術雑誌）

OBJECTIVES: To describe and examine trends in polypharmacy according to age in Japan from 2010 to 2016. DESIGN: Retrospective observational study. SETTING: Outpatient settings. PARTICIPANTS: Japanese individuals aged 20 and older. MEASUREMENTS: We analyzed pharmacy claims data that the Japanese Ministry of Health, Labor, and Welfare provided in the Survey of Medical Care Activities in Public Health Insurance from 2010 to 2016. The use of 5 or more oral prescription medications per month was defined as polypharmacy and of 10 or more as excessive polypharmacy. Regression analysis was used to estimate trends in polypharmacy with annual percentage changes. Using number of medications (polypharmacy vs excessive polypharmacy), trends in polypharmacy and crude and age-adjusted rates of polypharmacy per 1,000 persons were calculated according to year and age group (20-34, 35-49, 50-64, 65-79, ≥ 80). RESULTS: We analyzed 240 million pharmacy claims data. The age-adjusted monthly prevalence rate of polypharmacy increased from 85.2 to 93.8 per 1,000 persons per month and of excessive polypharmacy from 13.6 to 14.0 per 1,000 persons per month from 2010 to 2016 in the entire study population. The highest rate of polypharmacy (per 1,000 persons) was observed in 2016 in those aged 80 and older (326.8), followed by those aged 65 to 79 (167.3). The polypharmacy rate increased by 6.3% (95% confidence interval (CI)=4.0-8.7) per year from 2010 to 2012, then decreased by 0.7% (95% CI=-1.3-0.0) per year from 2012 to 2016. The rate of excessive polypharmacy increased by 4.5% (95% CI=1.1-8.0) per year from 2010 to 2013 and then decreased by 3.7% (95% CI=-6.7 to -0.6) per year from 2013 to 2016. CONCLUSION: The overall trend of polypharmacy in Japan increased during the study period, although the increase ceased in 2013 and then declined from 2013 to 2016. Policy changes in Japan might be responsible for some of the changes. J Am Geriatr Soc 66:2267-2273, 2018.

DOI： 10.1111/jgs.15569

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Oral shingles. 査読国際誌

Hagiya H, Nakagami F, Isomura E

BMJ case reports 11 ( 1 ) 2018年12月

Emergence of daptomycin non-susceptible coagulase-negative Staphylococci in patients with cardiovascular device infections: Two cases report investigated by whole genome analysis. 査読国際誌

Hagiya H, Sugawara Y, Kimura K, Hamaguchi S, Nishi I, Hayashi M, Akeda Y, Tomono K

Medicine 97 ( 49 ) e13487 2018年12月

Daptomycin-associated myopathy induced by concomitant administration of mirabegron. 査読国際誌

Hagiya H, Kokado R, Okuno H, Tomono K

Infection 47 ( 2 ) 331 - 332 2018年11月

Trends in incidence and mortality of tuberculosis in Japan: a population-based study, 1997-2016. 査読国際誌

Hagiya H, Koyama T, Zamami Y, Minato Y, Tatebe Y, Mikami N, Teratani Y, Ohshima A, Shinomiya K, Kitamura Y, Sendo T, Hinotsu S, Tomono K, Kano MR

Epidemiology and Infection 147 1 - 10 2018年11月

Broad-spectrum antibiotic prescriptions are unevenly discontinued throughout the week. 査読国際誌

Kokado R, Hagiya H, Morii D, Okuno H, Yamamoto N, Hamaguchi S, Yoshida H, Miwa Y, Tomono K

The Journal of hospital infection 101 ( 4 ) 471 - 474 2018年11月

Roseomonas mucosa bacteremia in a neutropenic child: A case report and literature review 国際誌

Kimura K, Hagiya H, Nishi I, Yoshida H, Tomono K

14 e00469 2018年11月

Neurosyphilis concurrently involving eye and ear. 査読国際誌

Futoshi Nakagami, Hideharu Hagiya, Kazuichi Maruyama, Yuri Onishi

BMJ case reports 2018 2018年10月

Reduced Seroprevalence of Hepatitis A Virus Among Japanese Healthcare Workers as a Risk Factor for Occupational Infection. 査読国際誌

Yoshioka N, Deguchi M, Hagiya H, Kagita M, Tomono K

Clinical laboratory 64 ( 10 ) 1791 - 1793 2018年10月

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