Faculty Profiles - HANAMOTO Katsumi

Papers - HANAMOTO Katsumi

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位相エンコーディング方向に現れる低信号アーチファクトの解析

花元克巳, 加藤博和, 澁谷光一, 川崎祥二, 黒田昌宏, 金澤右, 大野誠一郎, 門久繁文

Radiation Medicine 25 ( Suppl.I ) 92 - 92 2007.4

A comparative study on the characteristics of radioactivities and negative air ions originating from the minerals in some radon hot springs

Akihiro Sakoda, Katsumi Hanamoto, Naoto Haruki, Tomohiro Nagamatsu, Kiyonori Yamaoka

APPLIED RADIATION AND ISOTOPES 65 ( 1 ) 50 - 56 2007.1

Language：English Publishing type：Research paper (scientific journal) Publisher：PERGAMON-ELSEVIER SCIENCE LTD

To elucidate the characteristics of some radon hot springs, we simulated a hot spring by soaking the rocks for the radon therapy in water and measured the concentrations of radon and negative air ions in various conditions. In the results, the individual rock structure could contribute to radon leaching because the radon leaching rates were independent of the grain sizes. More negative air ions were generated by the wet rocks than by the dry rocks. (c) 2006 Elsevier Ltd. All rights reserved.

DOI： 10.1016/j.apradiso.2006.07.015

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天然放射性鉱石から水中への放射性核種の浸出率に及ぼす環境諸因子の比較検討

迫田晃弘, 花元克巳, 川辺睦, 永松知洋, 山岡聖典

日本放射線影響学会大会講演要旨集 49回 133 - 133 2006.9

Energy Response of an Optically Stimulated Luminescence Dosemeter to Low Energy Continuous X-rays(Part 2:Japanese Papers)

KAWABE Atsushi, SHIBUYA Koichi, HANAMOTO Katsumi, KOBAYASHI Ikuo, TAKEDA Yoshihiro

Japanese Journal of Health Physics 41 ( 4 ) 249 - 255 2006

Language：Japanese Publisher：Japan Health Physics Society

To investigate the energy response of an optically stimulated luminescence dosemeter (OSLD) with low energy photons, OSLDs were irradiated by low energy continuous X-rays which have various energy distributions. The effective energy of the X-ray was in the range 10.0-14.5keV, and homogeneity factor was in the range 0.5-0.9. As a result, at 11.0keV, the OSLD-to-ionization chamber ratio was maintained at almost a constant level from 1.03 at a 0.5 to 1.08 at a 0.7 homogeneity factor. However, the OSLD tended to overestimate measured value with an increase of effective energy. Probably, this error can be eliminated by calculating an appropriate correction factor.

DOI： 10.5453/jhps.41.249

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Other Link： https://jlc.jst.go.jp/DN/JALC/00289894802?from=CiNii

人工トロン温泉に由来する放射能とマイナスイオンの諸特性に関する検討

花元克巳, 迫田晃弘, 篠塚龍, 山岡聖典

日本放射線影響学会大会講演要旨集 48回 134 - 134 2005.11

バドガスタイン天然鉱石に由来する放射能と負(マイナス)イオンの諸特性に関する検討

迫田晃弘, 花元克巳, 川辺睦, 山岡聖典

日本放射線影響学会大会講演要旨集 48回 133 - 133 2005.11

Composition of MRI phantom equivalent to human tissues

H Kato, M Kuroda, K Yoshimura, A Yoshida, K Hanamoto, S Kawasaki, K Shibuya, S Kanazawa

MEDICAL PHYSICS 32 ( 10 ) 3199 - 3208 2005.10

Language：English Publishing type：Research paper (scientific journal) Publisher：AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS

We previously developed two new MRI phantoms (called the CAG phantom and the CAGN phantom), with T1 and T2 relaxation times equivalent to those of any human tissue at 1.5 T. The conductivity of the CAGN phantom is equivalent to that of most types of human tissue in the frequency range of 1 to 130 MHz. In this paper, the relaxation times of human tissues are summarized, and the composition of the corresponding phantoms are provided in table form. The ingredients of these phantoms are carrageenan as the gelling agent, GdCl3 as a T1 modifier, a-arose as a T2 modifier, NaCl (CAGN phantom only) as a conductivity modifier, NaN3 as an antiseptic, and distilled water. The phantoms have T1 values of 202-1904 ms and T2 values of 38-423 ms when the concentrations of GdCl3 and agarose are varied from 0-140 mu mol/kg, and 0%-1.6%, respectively, and the CAGN phantom has a conductivity of 0.27-1.26 S/m when the NaCl concentration is varied from 0%-0.7%. These phantoms have sufficient strength to replicate a torso without the use of reinforcing agents, and can be cut by a knife into any shape. We anticipate the CAGN phantom to be highly useful and practical for MRI and hyperthermia-related research. (9) 2005 American Association of Physicists in Medicine.

DOI： 10.1118/1.2047807

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Development of a new hybrid gel phantom using carrageenan and gellan gum for visualizing three-dimensional temperature distribution during hyperthermia and radiofrequency ablation

M Kuroda, H Kato, K Hanamoto, K Shimamura, T Uchida, Y Wang, S Akaki, JI Asaumi, K Himei, M Takemoto, S Kanazawa, K Shibuya, S Kawasaki, Y Hiraki

INTERNATIONAL JOURNAL OF ONCOLOGY 27 ( 1 ) 175 - 184 2005.7

Language：English Publishing type：Research paper (scientific journal) Publisher：SPANDIDOS PUBL LTD

We developed a new hybrid gel phantom using carrageenan and gellan gum for the purpose of visualizing three-dimensional temperature distribution. The phantom, which contains carrageenan, gellan gum, non-ionic surface active agent, potassium chloride, n-butanol, sodium azide, and water, shows good transparency at room temperature, and has the advantage that the heated region becomes white and opaque due to segregation of the surface active agent. Carrageenan and gellan gum were added to improve the transparency and fragility of the hybrid gel. Potassium chloride was used to adjust the electrical conductivity of the gel to a range of 5-130 MHz, so that it would be equivalent to that of muscle tissue for each frequency used by electromagnetic heating devices. N-butanol was used to adjust the clouding temperature to a range between 45 and 55 degrees C. In the present study we clarified the important properties of the new phantom, and developed formulae for easy determination of the amounts of ingredients necessary for the desired clouding temperature and electric conductivity. The characteristics of this phantom are: a) a solid form to avoid convection by heat conduction; b) sufficient strength without fragility to form a torso without the use of a reinforcing agent; c) high transparency at room temperature and visualization of the heating area as a white turbidity; d) time-lapse and accurate visualization of the changing temperature area without thermal hysteresis; e) electrical properties similar to those of human tissues; f) ease of production; and g) low cost and good safety. This phantom might assist oncologists in their routine checking and study of the performance of electromagnetic heating devices for hyperthermia and radiofrequency ablation.

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小型MRI装置用シーケンシャルパルスジェネレータの開発

花元克己, 加藤博和, 帆足正勝, 青山良宏, 西健二, 溝渕真一, 大胡文彦, 坂井千尋, 田中雅大, 馬場園喬, 黒田昌宏, 金澤右

日本医学放射線学会雑誌 65 ( 2 ) 154 - 154 2005.4

MnSOD遺伝子導入に伴うplating efficiencyの変化

黒田昌宏, 小松めぐみ, 王雅棣, 加藤博和, 花元克巳, 武本充広, 姫井健吾, 山本泰宏, 平木祥夫, 金澤右

日本医学放射線学会雑誌 65 ( 2 ) 161 - 161 2005.4

p53遺伝子,MnSOD遺伝子導入に伴う細胞死の検討

王雅棣, 黒田昌宏, 小松めぐみ, 加藤博和, 花元克己, 姫井健吾, 武本充広, 山本泰宏, 平木祥夫, 金澤右

日本医学放射線学会雑誌 65 ( 2 ) 161 - 161 2005.4

小型MRI装置用RFコイルの作製

加藤博和, 花元克巳, 青山良宏, 帆足正勝, 大胡文彦, 黒田昌宏, 金澤右, 溝渕真一, 西健二, 坂井千尋, 田中雅大, 馬場園喬

日本医学放射線学会雑誌 65 ( 2 ) 155 - 155 2005.4

The elevation of p53 protein level and SOD activity in the resident blood of the Misasa radon hot spring district

K Yamaoka, F Mitsunobu, S Kojima, M Shibakura, T Kataoka, K Hanamoto, Y Tanizaki

JOURNAL OF RADIATION RESEARCH 46 ( 1 ) 21 - 24 2005.3

Language：English Publishing type：Research paper (scientific journal) Publisher：JAPAN RADIATION RESEARCH SOC

To clarify the mechanism by which radon hot springs prevent cancer or not, in this study, blood was collected from residents in the Misasa hot spring district and in a control district. The level of a representative cancer-suppressive gene, p53, and the activity of a representative antioxidant enzyme, superoxide dismutase (SOD), were analyzed as indices. The level of serum p53 protein in the males in the Misasa hot spring district was found to be 2-fold higher than that in the control district, which is a significant difference. In the females in the Misasa hot spring district, SOD activity was approximately 15% higher than that in the control district, which is also statistically significant, and exceeded the reference range of SOD activity despite advanced age. These results suggested that routine exposure of the residents in the Misasa hot spring district to radon at a concentration about 3 times higher than the national mean induces trace active oxygen in vivo, potentiating products of cancer- suppressive gene and antioxidant function. As the p53 protein level was high in the residents in the Misasa hot spring district, apoptosis of cancer cells may readily occur.

DOI： 10.1269/jrr.46.21

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A comparative study on radioactive characteristics of the minerals for radon therapy

K Hanamoto, K Yamaoka

RADIATION MEASUREMENTS 39 ( 2 ) 157 - 160 2005.2

Language：English Publishing type：Research paper (scientific journal) Publisher：PERGAMON-ELSEVIER SCIENCE LTD

To elucidate the mechanism of the radon therapy, we analyzed the radioactive characteristics of the minerals in the famous regions for the radon therapy. Using a high-purity germanium detector, we measured the sludge at the hot bathroom with a high concentration of radon at Misasa Medical Center of Okayama University Medical School, the hokutolite, which was the same kind of mineral at Tamagawa Hot Spring in Japan, and the mineral at the gallery of Badgastein in Austria, which are celebrated regions for the radon therapy. As a result, the ratios of the uranium series to the thorium series for the sludge of Misasa, the hokutolite, and the mineral of Badgastein were 22, 50, and 0.94, respectively. The sludge of Misasa and the hokutolite mainly included the radioelements of the uranium series, while the mineral of Badgastein included the radioelements of both series with almost the same ratio. The ratio of the mineral of Badgastein is similar to that of background (1.1). Furthermore, two kinds of minerals, which are commercially available for radon therapy, were measured using the same detector. The ratios for the two minerals were 0.26 and 0.20, namely, the two minerals included larger radioelements of the thorium series than those of the uranium series. (C) 2004 Elsevier Ltd. All rights reserved.

DOI： 10.1016/j.radmeas.2004.04.008

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MRIファントムの開発

加藤博和, 花元克巳, 川崎祥二, 澁谷光一, 黒田昌宏, 吉村孝一, 吉田敦史, 津野田雅敏, 武本充広, 金澤右, 平木祥夫

日本医学放射線学会雑誌 65 ( 1 ) 77 - 78 2005.1

Study on Radioactivity and Negative Ion Originated from a Thoron Artificial Hot Spring

Akihiro SAKODA, Takahiro KATAOKA, Katsumi HANAMOTO, Kiyonori YAMAOKA

RADIOISOTOPES 54 ( 9 ) 375 - 383 2005

Simplification of analysis for comparison of radioactive characteristics and its application to some minerals for radon therapy Reviewed

K Hanamoto, K Yamaoka

HIGH LEVELS OF NATURAL RADIATION AND RADON AREAS: RADIATION DOSE AND HEALTH EFFECTS 1276 253 - 255 2005

Language：English Publishing type：Research paper (international conference proceedings) Publisher：ELSEVIER SCIENCE BV

To simplify the analysis of the radioactive characteristics of the minerals for the radon therapy, we developed a simple method to calculate the ratio of the uranium series to the thorium series (U/Th) without using activity. The ratios calculated by this method agreed well with the ratios calculated using the activity. We applied this method to some minerals for the radon therapy. As a result, the U/Th's for the sludge of Misasa, the hokutolite, the mineral of Badgastein, and the two kinds of commercially available minerals were 22, 50, 0.94, 0.26, and 0.20, respectively. (c) 2004 Elsevier B.V. All rights reserved.

DOI： 10.1016/j.ics.2004.09.029

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Effects of radon and thennal therapy on osteoarthritis Reviewed

K Yamaoka, F Mitsunobu, K Hanamoto, T Kataoka, Y Tanizaki

HIGH LEVELS OF NATURAL RADIATION AND RADON AREAS: RADIATION DOSE AND HEALTH EFFECTS 1276 249 - 250 2005

Language：English Publishing type：Research paper (international conference proceedings) Publisher：ELSEVIER SCIENCE BV

We examined the temporal changes in antioxidants, immune-, vasoactive- and pain-associated substances in human blood by therapy to elucidate the mechanism of osteoarthritis in which radon therapy is used as a treatment. Results showed that radon inhalation enhanced the antioxidation and immune function, and that the changes in vasoactive and pain-associated substances indicate increases in tissue perfusion brought about by radon therapy. (c) 2004 Published by Elsevier B.V.

DOI： 10.1016/j.ics.2004.12.013

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Development of a phantom compatible for MRI and hyperthermia using carrageenan gel-relationship between T-1 and T-2 values and NaCl concentration

A Yoshida, H Kato, M Kuroda, K Hanamoto, K Yoshimura, K Shibuya, S Kawasaki, M Tsunoda, S Kanazawa, Y Hiraki

INTERNATIONAL JOURNAL OF HYPERTHERMIA 20 ( 8 ) 803 - 814 2004.12

Language：English Publishing type：Research paper (scientific journal) Publisher：TAYLOR & FRANCIS LTD

The authors developed a phantom, designated as the CAGN phantom, compatible for MRI and hyperthermia that is useful in the fundamental studies of non-invasive MR thermometry. The ingredients of this phantom are carrageenan, GdCl3 as a T-1 modifier, agarose as a T-2 modifier, NaCl as a conductivity modifier, NaN3 as an antiseptic and distilled water. Another phantom that was developed, the CAG phantom, has relaxation times that are adjustable to those of any human tissue. To use this phantom for electromagnetic heating, NaCl was added to change the conductivity of the phantom and clarified the relationship between the conductivity and NaCl concentration. This study examined the relationship between relaxation times and NaCl concentration of the CAGN phantom. The results showed that both T-1 and T-2 values were affected by NaCl and the experimental results led to the empirical formulae expressing the relationship between the relaxation rates (1/T-1, 1/T-2) and the concentrations of GdCl3, agarose and NaCl. The appropriate concentrations of T-1 and T-2 modifiers were calculated from these empirical formulae when making a specified phantom that has the required relaxation times and NaCl concentration.

DOI： 10.1080/0265673042000199268

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MRIにおいて位相方向に出現するアーチファクト

大野誠一郎, 小水満, 花元克巳, 加藤博和, 黒田昌宏, 金澤右

日本放射線技術学会雑誌 60 ( 9 ) 1261 - 1261 2004.9

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