研究者詳細 - 長塚　仁

MISC - 長塚　仁

分割表示 270 件中 161 - 180 件目／全件表示 >>

Analysis of the epidermal growth factor receptor and related signaling molecules in head and neck squamous cell carcinoma

Al Sheikh Ali M, Gunduz M, Nagatsuka H, Tamamura R, Gunduz E, Katase N, Lefeuvre M, Shimizu K

岡山歯学会雑誌 28 ( 1 ) 97 2008年11月

Microsatellite analysis of ING tumor suppressor genes and relationship with clinicopathological features in ameloblastoma

Borkosky SS, Gunduz M, Katase N, Tamamura R, Nagatsuka H

岡山歯学会雑誌 28 ( 1 ) 96 - 97 2008年11月

シェーグレン症候群におけるヒト口唇腺中のβディフェンシンの発現パターン

山合友一朗, グンドゥズ・メーメット, 片瀬直樹, 長塚仁

Journal of Oral Biosciences 50 ( Suppl. ) 194 - 194 2008年9月

Examination of loss of heterozygosity in 1p36 chromosomal region in oral squamous cell carcinoma

Lefeuvre Mathieu, Gunduz Mehmet, Gunduz Esra, Al Sheik Ali Mahmoud, 片瀬直樹, Borkosky Silvia, 玉村亮, 長塚仁

Journal of Oral Biosciences 50 ( Suppl. ) 157 - 157 2008年9月

頭頸部扁平上皮癌におけるDkk遺伝子ファミリーのLOH解析

片瀬直樹, メーメット・グンデゥズ, エスラ・グンデゥズ, マームド・アルシェイクアリ, 井上美穂, アンドレア・ロドリゲス, 胡海龍, 長塚仁

日本病理学会会誌 97 ( 1 ) 318 - 318 2008年3月

口腔悪性黒色腫におけるKIT遺伝子機能獲得型突然変異とc-kit蛋白発現

長塚仁, Rivera Rosario, Huat Siar Chong, Gunduz Mehmet, 玉村亮, 片瀬直樹, 永井教之

日本病理学会会誌 97 ( 1 ) 221 - 221 2008年3月

口腔の病態を診る歯肉増殖症を診る.

片瀬直樹, 長塚仁

DENTAL DIAMOND 33 ( 2 ) 20 - 23 2008年

口腔の病態を診る口唇・口蓋裂を診る.

長塚仁, 片瀬直樹

DENTAL DIAMOND 33 ( 13 ) 16 - 19 2008年

口腔の病態を診る扁平上皮癌を診る.

片瀬直樹, 長塚仁

DENTAL DIAMOND 33 ( 6 ) 66 - 69 2008年

Sequential expressions of Notch1, Jagged2 and Math1 in molar tooth germ of mouse 国際誌

Silvia S. Borkosky, Hitoshi Nagatsuka, Yorihisa Orita, Hidetsugu Tsujigiwa, Junko Yoshinobu, Mehmet Gunduz, Andrea P. Rodriguez, Liliana R. Missana, Kazunori Nishizaki, Noriyuki Nagai

Biocell 32 ( 3 ) 251 - 257 2008年

記述言語：英語出版者・発行元：INST HISTOL EMBRIOL-CONICET

The Notch signaling pathway is an evolutionary conserved mechanism that plays an important role in cell-cell communication and cell fate in a wide range of tissues. The mammalian family of Notch receptors consists of 4 members: Notch1/2/3/4. The Notch ligand family consists of 5 members: Delta1/3/4 and Jagged1/2. Math1 encodes a murine basic helix-loop-helix (bHLH) transcription factor that acts as positive regulator of cell differentiation. Recently, links between Notch and Math1 pathways were demonstrated in various tissues. Expression of Notch1, Jagged2 and Math1 were analyzed in the mouse molar tooth germ during embryonic stage (E) 13 and E15 and during postnatal stage (PN) 1, PN3, PN5, PN10 and PN14 by using in situ hybridization. Positive Notch1 expression was found at the tooth bud during embryonic stages, but its expression was absent from the basal cells in contact with the dental mesenchyme. Jagged2 and Math1 were strongly expressed in differentiated ameloblasts and odontoblasts and Math1 strong expression was even maintained until PN14 stage. Math1 showed the strongest expression. Our results suggest that the Notch1 signaling pathway through Jagged2 could be importantly related to Math1, directing the process of odontogenesis toward cell differentiation.

A basic research of CaTiO_3-C as a coating material for implants(Oral Session,The 16th Annual Meeting of the Society for Hard Tissue Regenerative Biology in Matsumoto Dental University)

Hu HaiLong, Okauchi Mika, Tamamura Ryo, Rodrigez Andrea Paola, Inoue Miho, Nakano Keisuke, Sagae Toshiro, Nagatsuka Hitoshi, Takagi Toru, Nagai Noriyuki

Journal of hard tissue biology 16 ( 3 ) 149 - 149 2007年12月

Involvement of CD81 in abnormal growth of RA synovial cells(Oral Session,The 16th Annual Meeting of the Society for Hard Tissue Regenerative Biology in Matsumoto Dental University)

Mori Hiroki, Nagatsuka Hitoshi, Tamamura Ryo, Nishida Keiichiro, Nakajima Toshihiro, Nagai Noriyuki, Nakanishi Tohru

Journal of hard tissue biology 16 ( 3 ) 150 - 150 2007年12月

An investigation of the ability to differentiate to dental tissue cells of the bone marrow derived mesenchymal stem cells(Oral Session,The 16th Annual Meeting of the Society for Hard Tissue Regenerative Biology in Matsumoto Dental University)

Tsujigiwa Hidetsugu, Nagatsuka Hitoshi, Rodriguez Andrea Paola, Hu Hailong, Yamada Masao, Nagai Noriyuki

Journal of hard tissue biology 16 ( 3 ) 151 - 151 2007年12月

Notch signaling in malignant tranceforming of odontogenic tumor(Oral Session,The 16th Annual Meeting of the Society for Hard Tissue Regenerative Biology in Matsumoto Dental University)

Nakano Keisuke, Nagatsuka Hitoshi, Tsujigiwa Hidetsugu, Shimizu Takako, CH Siar, Nagai Noriyuki, Kawakami Toshiyuki

Journal of hard tissue biology 16 ( 3 ) 151 - 152 2007年12月

Evaluation of CaTiO_3-C in vitro study(Oral Session,The 16th Annual Meeting of the Society for Hard Tissue Regenerative Biology in Matsumoto Dental University)

Inoue Miho, Rodriguez Andrea P., Okauchi Mika, Tamamura Ryo, Hu Hailong, Inoue Masahisa, Nagatsuka Hitoshi, Takagi Tohru, Nagai Noriyuki

Journal of hard tissue biology 16 ( 3 ) 149 - 149 2007年12月

A pigmented calcifying cystic odontogenic tumor associated with compound odontoma: a case report and review of literature. 国際誌

Phuu P Han, Hitoshi Nagatsuka, Chong H Siar, Hidetsugu Tsujigiwa, Mehmet Gunduz, Ryo Tamamura, Silvia S Borkosky, Naoki Katase, Noriyuki Nagai

Head & face medicine 3 ( 1 ) 35 - 35 2007年9月

記述言語：英語

BACKGROUND: Pigmented intraosseous odontogenic lesions are rare with only 47 reported cases in the English literature. Among them, pigmented calcifying cystic odontogenic tumor, formerly known as calcifying odontogenic cyst, is the most common lesion with 20 reported cases. METHODS: A case of pigmented calcifying cystic odontogenic tumor associated with odontoma occurring at the mandibular canine-premolar region of a young Japanese boy is presented with radiographic, and histological findings. Special staining, electron microscopic study and immunohistochemical staining were also done to characterize the pigmentation. RESULTS: The pigments in the lesion were confirmed to be melanin by Masson-Fontana staining and by transmission electron microscopy. The presence of dendritic melanocytes within the lesion was also demonstrated by S-100 immunostaining. CONCLUSION: The present case report of pigmented calcifying cystic odontogenic tumor associated with odontoma features a comprehensive study on melanin and melanocytes, including histochemical, immunohistochemical and transmission electron microscopic findings.

DOI： 10.1186/1746-160X-3-35

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頭頸部癌における癌抑制遺伝子ファミリー新規メンバーING3及びING4の分子生物学的解析

グンデウズ・エスラ, グンデウズ・メーメット, 長塚仁, 片瀬直樹, マシュー・ルフェーブル, 永井教之

Journal of Oral Biosciences 49 ( Suppl. ) 187 - 187 2007年8月