研究者詳細 - 清田　洋正

論文 - 清田　洋正

分割表示 235 件中 61 - 80 件目／全件表示 >>

A new germacrane sesquiterpenolide isolated from Artemisia frigida

Manli Zhang, Zhiyu Ni, Cunfang Li, Yufang Wang, Mei Dong, Francoise Sauriol, Changhong Huo, Qingwen Shi, Teiko Yamada, Hiromasa Kiyota, Yucheng Gu, Bin Cong

CHEMISTRY OF NATURAL COMPOUNDS 49 ( 4 ) 626 - 628 2013年9月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：SPRINGER

A novel germacrane sesquiterpenolide was isolated from the whole plant of Artemisia frigida. The structure was characterized as 1 alpha,3 alpha-dihydroxy-7 beta,11 alpha H-germacra-4Z,10(14)-dien-12,6 alpha-olide (1) on the basis of spectroscopic methods.

DOI： 10.1007/s10600-013-0694-x

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Xylomexicanins C and D, New Mexicanolide-Type Limonoids from Xylocarpus granatum

YI-BING WU, ZHI-YU NI, CHANG-HONG HUO, JIAN SU, MEI DONG, FRAN?OISE SAURIOL, QING-WEN SHI, YU-CHENG GU, and HIROMASA KIYOTA*

Bioscience, Biotechnology, and Biochemistry 77 ( 4 ) 736 - 740 2013年4月

Torreyanoxane, a New 3,4-Seco-glutinane Triterpenoid Isolated from Torreya nucifera

Cong-Mei Cao, Man-Li Zhang, Mei Dong, Fran?oise Sauriol, Chang-Hong Huo, Qing-Wen Shi, Yu-Cheng Gu, Hiromasa Kiyota*, Bin Cong

Helvetica Chimica Acta 96 ( 3 ) 375 - 378 2013年3月

Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors

Christopher J. Vavricka, Yue Liu, Hiromasa Kiyota, Nongluk Sriwilaijaroen, Jianxun Qi, Kosuke Tanaka, Yan Wu, Qing Li, Yan Li, Jinghua Yan, Yasuo Suzuki, George F. Gao

Nature Communications 4 1491 - 1491 2013年2月

Cytotoxic Flavonoids from the Flowers of Achillea millefolium

Chang-Hong Huo, Yong Li, Mei Dong, Man-Li Zhang, Yu-Fang Wang, Qing Zhang, Fang Qin, Qing-Wen Shi, Hiromasa Kiyota*

Chemistry of Natural Compounds 48 ( 6 ) 958 - 962 2013年1月

A new alkaloid taxane composed of two N-formyl rotamers from the rooted cuttings of Taxus canadensis

Hong-Zhen Zhang, Yu-Fang Wang, Man-Li Zhang, Mei Dong, Chang-Hong Huo, Francoise Sauriol, Qing-Wen Shi, Yu-Cheng Gu, Hui-Lan Wang, Hiromasa Kiyota

Chemistry of Natural Compounds 48 ( 6 ) 1035 - 1038 2013年1月

記述言語：英語掲載種別：研究論文（学術雑誌）

A taxane with an amino-side chain on C-5 was identified for the first time from rooted cuttings of the Canadian yew, Taxus canadensis. The structure was characterized as 2α,10β,13α-triacetoxy-5α-[3'-(N-formyl- Nmethylamino)-3'-phenylpropanoyloxy]taxa-4(20),12-dien-9α-ol (1) on the basis of 1D and 2D NMR data and HR-FAB-MS analyses. The spectra revealed that in CDCl3 solution 1 was composed of two rotamers (1a and 1b) in a ratio of approximately 1:1. © 2013 Springer Science+Business Media New York.

DOI： 10.1007/s10600-013-0458-7

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Constituents from Salvia species and Their Biological Activities

Yi-Bing Wu, Zhi-Yu Ni, Qing-Wen Shi, Mei Dong, Hiromasa Kiyota*, Yu-Cheng Gu, Bin Cong

Chemical Reviews 112 ( 11 ) 5967 - 6026 2012年11月

Hybrid Stereoisomers of a Compact Molecular Probe Based on a Jasmonic Acid Glucoside: Syntheses and Biological Evaluations

Minoru Ueda, Gangquiang Yang, Yasuhiro Ishimaru, Tetsuya Itabashi, Satoru Tamura, Hiromasa Kiyota, Shigefumi Kuwahara, Sho Inomata, Mitsuru Shoji, and Takeshi Sugai

Bioorganic and Medicinal Chemistry 20 ( 19 ) 5832 - 5843 2012年10月

New 686-Taxanes Isolated from the Heartwood of Taxus cuspidata

Kai Zhang, Yong-Li Wang, Zhi-Yu Ni, Man-Li Zhang, Yu-Fang Wang, Mei Dong, Qing-Wen Shi, Chang-Hong Huo, Fran?oise Sauriol, Hiromasa Kiyota*, Yu-Cheng Gu, Bin Cong

Helvetica Chimica Acta 95 ( 9 ) 1566 - 1572 2012年9月

Antitumour Activities of Sesquiterpene Lactones from Inula helenium and Inula japonica

Yong Li, Zhi-Yu Ni, Meng-Chu Zhu, Mei Dong, Si-Ming Wang, Qing-Wen Shi, Man-Li Zhang, Yu-Fang Wang, Chang-hong Huo, Hiromasa Kiyota, Bin Cong

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES 67 ( 7-8 ) 375 - 380 2012年7月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：VERLAG Z NATURFORSCH

Eight sesquiterpene lactones were isolated from the roots of Inula helenium and flowers of I. japonica. Among them, isoalantolactone (3) and santamarine (6) exhibited significant growth inhibitory activities against gynecologic cancer cell lines, while others weakly inhibited the growth of the cell lines (IC50 <= 100 mu m). In addition, 3 significantly inhibited the tumour growth of S180 tumour-bearing mice. Compounds 3 and 6 were not toxic to human embryonic lung fibroblast cells in vitro. These results demonstrated that the antitumour activities are closely related to the structures of the compounds, that is, an alpha-exomethylene-gamma-lactone ring is necessary for these activities.

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A Simple, Rapid Method for Gizzerosine Analysis in Fish Meal by Pper Electrophoresis

Zhi-Hua Tao, Minoru Sato, Ke-Gang Wu, Hiromasa Kiyota, Toshiyasu Yamaguchi, Toshiki Nakano

Fisheries Science 78 ( 4 ) 923 - 926 2012年7月

Achillinin B and C, new sesquiterpene dimers isolated from Achillea millefolium

Yong Li, Meng-Chu Zhu, Man-Li Zhang, Yu-Fang Wang, Mei Dong, Qing-Wen Shi, Chang-Hong Huo, Francoise Sauriol, Hiromasa Kiyota, Yu-Cheng Gu, Bin Cong

TETRAHEDRON LETTERS 53 ( 21 ) 2601 - 2603 2012年5月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：PERGAMON-ELSEVIER SCIENCE LTD

Two novel sesquiterpene dimers, achillinin B and C, were isolated from the flowers of Achillea millefolium. The structures were elucidated by extensive spectroscopic analysis. A plausible biosynthetic pathway of achillinin B and C by Diels-Alder reaction of the corresponding guaiane sesquiterpenoids is also discussed. (C) 2012 Elsevier Ltd. All rights reserved.

DOI： 10.1016/j.tetlet.2012.03.039

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Millifolides A-C. New 1,10-Seco-guaianolides from the Flowers of Achillea millefolium

Yong Li, Zhi-Yu Ni, Meng-Chu Zhu, Kai Zhang, Yi-Bing Wu, Mei Dong, Qing-Wen Shi, Chang-Hong Huo, Francoise Sauriol, Hiromasa Kiyota, Yu-Cheng Gu, Bin Cong

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES 67 ( 5 ) 438 - 446 2012年5月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：VERLAG Z NATURFORSCH

Ten 1,10-secoguaianolides were isolated from the flowers of Achillea millefolium. Their structures were determined on the basis of spectroscopic methods. Three of them (millifolides A-C) including two dimeric sesquiterpenoids exhibit new skeletons. Seco-tanapartholide A exhibited moderate cell growth inhibitory activity against the human cancer cell line MCF7WT (IC50 = 5.51 mu m) in vitro.

DOI： 10.5560/ZNB.2012-0028

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Canataxpyran A, a novel 3,8-secotaxane with a 13,17-ether bridge from needles of Taxus canadensis

Yong Li Man-Li Zhang, Yu-Fang Wang, Mei Dong, Fran?oise Sauriol, Qing-Wen Shi, Hiromasa Kiyota*, Yu-Cheng Gu, Bin Cong,

Heterocyclic Communications 18 ( 2 ) 57 - 60 2012年4月

Relationship between Structure and Microtubule Polymerization Activity of Taxane Derivatives

Masafumi Hidaka, Tomoe Koga, Hiromasa Kiyota, Tohru Horiguchi, Qing-Wen Shi, Keiko Hirose, Takafumi Uchida

Biosci. Biotechnol. Biochem. 76 ( 2 ) 349 - 352 2012年2月

Structure-activity relationship of 9-methylstreptimidone that induces selective apoptosis in adult T-cell leukemia cells

Masatoshi Takeiri, Eisuke Ota, Shigeru Nishiyama, Hiromasa Kiyota, and Kazuo Umezawa

Oncology Research 20 ( 1 ) 7 - 14 2012年

Natural Taxanes: Developments Since 1828

Yu-Fang Wang, Qing-Wen Shi, Mei Dong, Hiromasa Kiyota*, Yu-Cheng Gu, Bin Cong

Chemical Reviews 111 ( 12 ) 7652 - 7709 2011年12月

Synthesis and Biotransformation of Plausible Biosynthetic Intermediates of Salicylaldehyde-Type Phytotoxins of Rice Blast Fungus, Magnaporthe grisea

Koji Tanaka, Ayaka Sasaki, Hai-Qun Cao, Teiko Yamada, Masahiro Igarashi, Isao Komine, Hirokazu Nakahigashi, Naoko Minami, Shigefumi Kuwahara, Manabu Nukina, Hiromasa Kiyota

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY ( 31 ) 6276 - 6280 2011年11月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：WILEY-BLACKWELL

Rice blast fungus, Magnaporthe grisea, produces a series of salicylaldehyde-type phytotoxins such as pyriculol, pyricuol, and pyriculariol. Plausible biosynthetic intermediates of these phytotoxins were synthesized in deuterium labeled forms using the Stille coupling reaction as the key step, and subjected to biotransformation by the fungus. Heptatrienyl-salicylaldehyde was converted into dihydropyriculol by the fungus by a shaking culture. A new biosynthetic pathway comprising both oxidation and reduction is proposed.

DOI： 10.1002/ejoc.201100771

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Synthesis of Both Enantiomers of omega-Trifluorononactic Acid, a New Analogue of Nonactin Monomers

Kentaro Takai, Tadaatsu Hanadate, Shuichi Oi, Teiko Yamada, Shigefumi Kuwahara, Hiromasa Kiyota

SYNTHESIS-STUTTGART ( 22 ) 3741 - 3748 2011年11月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：GEORG THIEME VERLAG KG

Both (+)- and (-)-omega-trifluorononactic acid, a designed analogue of nonactic acid, were synthesized. The racemic acid, prepared by using cis-selective iodoetherification, was resolved as the corresponding (S)-O-acetylmandelates. The structure was determined by X-ray crystallographic analysis.

DOI： 10.1055/s-0030-1260234

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Diabietane Ether, a New Dimeric Abietane with an Ether Linkage from Taxus cuspidata Needles

Zhi-Yu Ni, Yi-Bing Wu, Mei Dong, Man-Li Zhang, Yu-Fang Wang, Francoise Sauriol, Chang-Hong Huo, Qing-Wen Shi, Yu-Cheng Gu, Hiromasa Kiyota, Bin Cong

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES 66 ( 10 ) 1083 - 1086 2011年10月

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