Faculty Profiles - TOYOOKA Shinichi

Papers - TOYOOKA Shinichi

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左肺全摘、大網充填術後に胃の通過障害を来した1例

枝園和彦, 豊岡伸一, 岡崎幹生, 山根正修, 羽藤慎二, 大藤剛宏, 内藤稔, 土井原博義, 佐野由文

岡山医学会雑誌 120 ( 2 ) 249 - 249 2008.8

Non-BAC component but not epidermal growth factor receptor gene mutation is associated with poor outcomes in small adenocarcinoma of the lung. Reviewed

Kobayashi N, Toyooka S, Ichimura K, Soh J, Yamamoto H, Matsuo K, Otani H, Jida M, Kubo T, Tsukuda K, Kiura K, Sano Y, Date H

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 3 ( 7 ) 704 - 710 2008.7

DNA methylation in lung cancer. Reviewed

Toyooka S, Matsuo K, Gazdar AF

The New England journal of medicine 358 ( 23 ) 2513; author reply 2514 2008.6

Mutational and epigenetic evidence for independent pathways for lung adenocarcinoma

TOYOOKA Shinichi, DATE Hiroshi

120 ( 1 ) 7 - 11 2008.5

組織型が非常に稀な悪性胸膜中皮腫の1例

山本寛斉, 豊岡伸一, 肥後貴子, 岡崎幹生, 田尾裕之, 河本純一, 山根正修, 大藤剛宏, 佐野由文, 伊達洋至

岡山医学会雑誌 120 ( 1 ) 119 - 119 2008.5

ゲフィチニブ単剤療法が施行された肺非小細胞癌における予後因子としての血清KL-6

藤原義朗, 木浦勝行, 瀧川奈義夫, 豊岡伸一, 堀田勝幸, 宗淳一, 宮原信明, 谷本安, 金廣有彦, 田端雅弘, 加藤勝也, 伊達洋至, 谷本光音

日本呼吸器学会雑誌 46 ( 増刊 ) 131 - 131 2008.5

悪性中皮腫の診断・治療の進歩悪性中皮腫に対する当院の治療成績と問題点

藤井昌学, 瀧川奈義夫, 木浦勝行, 豊岡伸一, 大谷真二, 佐野由文, 田端雅弘, 谷本光音, 伊達洋至

気管支学 30 ( Suppl. ) S98 - S98 2008.5

IIIB期非小細胞肺癌に対する外科的治療は妥当か?

佐野由文, 豊岡伸一, 岡崎幹生, 田尾裕之, 山根正修, 大藤剛宏

日本呼吸器外科学会雑誌 22 ( 3 ) 549 - 549 2008.4

A novel strategy for treatment of metastatic pulmonary tumors: radiofrequency ablation in conjunction with surgery. Reviewed

Sano Y, Kanazawa S, Mimura H, Gobara H, Hiraki T, Fujiwara H, Yamane M, Toyooka S, Oto T, Date H

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 3 ( 3 ) 283 - 288 2008.3

Language：English Publishing type：Research paper (scientific journal) Publisher：ELSEVIER SCIENCE INC

Introduction: Local treatment that includes surgical resection of metastatic pulmonary tumors is controversial because of the biologic features and invasiveness of these tumors. We report our experience with a premeditated treatment involving combined computed tomography-guided radiofrequency ablation and surgical resection in three patients with metastatic pulmonary tumors.Methods: Three patients underwent radiofrequency ablation in conjunction with surgical resection. The first was a 67-year-old man with pulmonary metastases of bronchial adenoid cystic carcinoma. We performed partial resection of five tumors in the right lung and ablated a tumor in the left lung. The second was a 66-year-old man with pulmonary metastases of renal cell carcinoma. He underwent radiofrequency ablation for three tumors in the right upper and middle lobes, and right lower lobectomy for tumors in that lobe. The third was a 55-year-old man with pulmonary metastases of high-grade sarcoma of the right thigh. We performed partial resection of five tumors in the left lung and ablated a tumor in the right lung.Results: Two patients had metastatic lesions on both sides of the lung; we performed surgical resection on one side and radiofrequency ablation contralaterally to avoid bilateral thoracotomy. The third patient underwent surgical resection and radiofrequency ablation to avoid highly invasive right pneumonectomy. All patients survived for more than 1 1/2 years after combination therapy.Conclusions: Premeditated treatment involving a combination of radiofrequency ablation and surgical resection can be a useful option in patients with metastatic pulmonary tumors, improving curability and avoiding highly invasive procedures.

DOI： 10.1097/JTO.0b013e3181645443

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Dry small pleural dissemination of adenocarcinoma of the lung preoperatively detected by PET/CT: a report of two cases. Reviewed

Okutani D, Yamane M, Toyooka S, Oto T, Aoe M, Sano Y, Date H

Acta medica Okayama 62 ( 1 ) 55 - 58 2008.2

Long-term follow-up of living-donor single lobe transplantation for idiopathic pulmonary arterial hypertension in a child. Reviewed

Toyooka S, Sano Y, Yamane M, Oto T, Okazaki M, Kusano KF, Date H

The Journal of thoracic and cardiovascular surgery 135 ( 2 ) 451 - 452 2008.2

Epidermal growth factor receptor mutation, but not sex and smoking, is independently associated with favorable prognosis of gefitinib-treated patients with lung adenocarcinoma. Reviewed

Toyooka S, Takano T, Kosaka T, Hotta K, Matsuo K, Ichihara S, Fujiwara Y, Soh J, Otani H, Kiura K, Aoe K, Yatabe Y, Ohe Y, Mitsudomi T, Date H

Cancer science 99 ( 2 ) 303 - 308 2008.2

Postoperative perforation in the bronchus intermedius membrane after a primary lung cancer resection Reviewed

Yuji Hirarni, Shinichi Toyooka, Yoshifumi Sano, Hiroshi Date

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY 33 ( 1 ) 130 - 132 2008.1

Language：English Publishing type：Research paper (scientific journal) Publisher：ELSEVIER SCIENCE BV

We experienced 4 cases of postoperative perforation in the bronchus intermedius membrane (PBIM) after primary lung cancer resection. Three patients had undergone a right lower lobectomy and 1 patient had undergone a right upper lobectomy; as part of a systemic lymph node dissection, the subcarinal lymph node (Station 7) was dissected in all cases. Leakages were detected on postoperative days 3, 10, 11, and 26, respectively. The clinical signs of PBIM included the appearance of sputum like pleural effusion, decreased oxygenation, elevated inflammatory markers, pneumothorax, and infected pleural effusion. PBIM was confirmed by bronchofiberscopy. Direct suturing of the perforated membrane, followed by rapping with an omental flap was performed in 1 case; completion bitobectomies, followed by rapping of the bronchial stump with an omental flap or an intercostal muscle flap were performed in 2 cases; and a completion pneumonectomy, followed by rapping of the bronchial stump with an omental flap was performed in 1 case. All 4 of the cases were successfully treated. (c) 2007 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.

DOI： 10.1016/j.ejcts.2007.09.038

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Current status and potential of living-donor lobar lung transplantation. Reviewed

Date H, Yamane M, Toyooka S, Okazaki M, Aoe M, Sano Y

Frontiers in bioscience : a journal and virtual library 13 1433 - 1439 2008.1