研究者詳細 - 神田　秀幸

Nutritional effects on depressive symptoms in Parkinson's disease patients 査読

T. Fukushima, X. Tan, Y. Luo, P. Wang, J. Song, H. Kanda, T. Hayakawa, T. Kakamu, M. Tsuji

EUROPEAN JOURNAL OF NEUROLOGY 19 397 - 397 2012年9月

中高生の睡眠を取り巻く環境に関する疫学研究

池田真紀, 兼板佳孝, 井谷修, 近藤修治, 簑輪眞澄, 鈴木健二, 樋口進, 神田秀幸, 尾崎米厚, 大井田隆

日本睡眠学会定期学術集会プログラム・抄録集 37回 287 - 287 2012年6月

日本の青少年における寝ぼけと歯ぎしりについての疫学的研究

井谷修, 兼板佳孝, 池田真紀, 近藤修治, 簑輪眞澄, 鈴木健二, 樋口進, 神田秀幸, 尾崎米厚, 大井田隆

日本睡眠学会定期学術集会プログラム・抄録集 37回 287 - 287 2012年6月

Nutritional effects on depressive symptoms in Parkinson's disease patients 査読

Tetsuhito Fukushima, Xiaodong Tan, Yunwen Luo, Puqing Wang, Jinhui Song, Hideyuki Kanda, Takehito Hayakawa, Takeyasu Kakamu, Masayoshi Tsuji

e-SPEN Journal 7 ( 2 ) e64 - e68 2012年4月

記述言語：英語掲載種別：研究論文（学術雑誌）

Background &amp
aims: Factors associated with depression in Parkinson's disease, especially lifestyle and nutrition, have been poorly studied. Our study was conducted to investigate nutritional factors associated with depression in Parkinson's disease. Methods: The subjects were 82 Parkinson's disease patients and the same number of sex and age-matched controls recruited from the outpatient clinic of Xiangfan No. 1 People's Hospital in Hubei, China between 2006 and 2008. The Parkinson's disease patients were divided into two groups, 24 Parkinson's disease with depression and 58 Parkinson's disease without depression. DSM-IV criteria was used for the primary diagnosis of depressive disorders. The severity of depression in patients was assessed by the criteria of the Hamilton Depression Rating Scale (HAMD-17), and a score ≥14 was defined as "depression". Information about eating habits and other factors was obtained by subject recall of state prior to diagnosis of Parkinson's disease and depression. Results: Compared with the Parkinson's disease patients without depression and the controls, the Parkinson's disease patients with depression had relatively low levels of income and education. Fat and vitamin B1 intake was significantly higher in the Parkinson's disease patients with depression than in both the Parkinson's disease patients without depression and the controls. Bean product intake was significantly lower in the Parkinson's disease patients with depression than in both the Parkinson's disease patients without depression and the controls. Conclusions: Less fat and vitamin B1 but more bean product intake might be associated with a lower risk for depression in Parkinson's disease patients from a higher income bracket with better educational background. © 2012 European Society for Clinical Nutrition and Metabolism.

DOI： 10.1016/j.clnme.2012.02.002

Scopus

【健康増進・地域医療・医療費適正化計画とデータ活用〜生活習慣病の予防・治療システムの戦略的構築へ〜】生活習慣病の予防と医療費 10年間の追跡調査による健診所見と医療費の関連滋賀国保コホート研究の知見から

岡村智教, 中村幸志, 早川岳人, 神田秀幸, 三浦克之, 岡山明, 上島弘嗣

日本衛生学雑誌 67 ( 1 ) 38 - 43 2012年1月

[Effect of cardiovascular risk factors on individual and population medical expenditures: a 10-year cohort study of 4,535 National Health Insurance beneficiaries in Shiga]. 査読

Tomonori Okamura, Koshi Nakamura, Takehito Hayakawa, Hideyuki Kanda, Katsuyuki Miura, Akira Okayama, Hirotsugu Ueshima

Nihon eiseigaku zasshi. Japanese journal of hygiene 67 ( 1 ) 38 - 43 2012年1月

記述言語：日本語掲載種別：研究論文（学術雑誌）

A 10-year follow-up cohort study of 4,535 National Health Insurance beneficiaries aged 40 to 69 years in Shiga was performed as part of a research project conducted by the Health Promotion Research Committee of the Shiga National Health Insurance Organizations in 2002. The relationship between cardiovascular risk factors and medical expenditures during the 10-year study period has been examined in this cohort. For example, there was a positively graded correlation between blood pressure and individual total medical expenditures per month. The odds ratio for cumulative hospitalization and hazard ratio for all-cause mortality in severe hypertensives were also higher than those in normotensives. However, from the viewpoint of the entire population, the excess medical expenditures attributable to hypertension within the total medical expenditures were higher for mild-to-moderate hypertensives than for severe hypertensives. On the other hand, although individual medical expenditures per month were 1.7-fold higher for participants with 2 or 3 risk factors and obesity, which was broadly equivalent to metabolic syndrome, than for those without these factors, the excess medical expenditures determined by risk clustering within the total medical expenditures were higher in normal-weight people than in obese people because of the higher prevalence of normal weight. These findings suggest that high-risk individuals are a good target of a high-risk approach, such as intensive health guidance, from the viewpoint of medical expenditures. However, another approach for the majority with a low-to-moderate cardiovascular risk should be considered, because they account for a greater proportion of the excess medical expenditures. Another way to solve this problem may be a population approach with an effective method of providing information to citizens.

DOI： 10.1265/jjh.67.38

Mobile phone use does not discourage adolescent smoking in Japan. 査読国際誌

Yoneatsu Osaki, Takashi Ohida, Hideyuki Kanda, Yoshitaka Kaneita, Takuji Kishimoto

Asian Pacific journal of cancer prevention : APJCP 13 ( 3 ) 1011 - 4 2012年

記述言語：英語掲載種別：研究論文（学術雑誌）

OBJECTIVE: The possibility that smoking prevalence among junior and senior high school students may decrease with increasing mobile phone bill was reported by the mass media in Japan. We conducted a nationwide survey on adolescent smoking and mobile phone use in Japan in order to assess the hypothesis that mobile phone use has replaced smoking. METHODS: A total of 70 junior high schools (response rate; 71%), and 69 high schools (90%) from all over Japan responded to 2005 survey. Students in the responding schools were asked to fill out an anonymous questionnaire about smoking behavior, mobile phone bill, and pocket money. Questionnaires were collected from 32,615 junior high school students and 48,707 senior high school students. RESULTS: The smoking prevalence of students with high mobile phone bill was more likely to be high, and that of students who used mobile phones costing 10,000 yen and over per month was especially high. When "quitters" were defined as students who had tried smoking but were not smoking at the time of survey, the proportion of quitters decreased as the mobile phone bill increased. The proportion of students who had smoking friends increased with the increase in the mobile phone bill per month. CONCLUSION: The hypothesis that the decrease in smoking prevalence among Japanese adolescents that has been observed in recent years is due to a mobile phone use can be rejected.

[Effects of the great East Japan earthquake on industries and laborers in Fukushima prefecture].

Takeyasu Kakamu, Hideyuki Kanda, Masayoshi Tsuji, Takehito Hayakawa, Tetsuhito Fukushima

Sangyō eiseigaku zasshi = Journal of occupational health 54 ( 1 ) 37 2012年

The Association between Use of Mobile Phones after Lights Out and Sleep Disturbances among Japanese Adolescents: A Nationwide Cross-Sectional Survey

Takeshi Munezawa, Yoshitaka Kaneita, Yoneatsu Osaki, Hideyuki Kanda, Masumi Minowa, Kenji Suzuki, Susumu Higuchi, Junichiro Mori, Ryuichiro Yamamoto, Takashi Ohida

SLEEP 34 ( 8 ) 1013 - 1020 2011年8月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：OXFORD UNIV PRESS INC

Study Objective: The objective of this study was to examine the association between the use of mobile phones after lights out and sleep disturbances among Japanese adolescents.Design and Setting: This study was designed as a cross-sectional survey. The targets were students attending junior and senior high schools throughout Japan. Sample schools were selected by cluster sampling. Self-reported anonymous questionnaires were sent to schools for all students to fill out.Participants: A total of 95,680 adolescents responded. The overall response rate was 62.9%, and 94,777 questionnaires were subjected to analysis.Intervention: N/AMeasurements and Results: Daily mobile phone use, even if only for a brief moment everyday, was reported by 84.4%. Moreover, as for use of mobile phones after lights out, 8.3% reported using their mobile phone for calling every day and 17.6% reported using it for sending text messages every day. Multiple logistic regression analysis showed that mobile phone use for calling and for sending text messages after lights out was associated with sleep disturbances (short sleep duration, subjective poor sleep quality, excessive daytime sleepiness, and insomnia symptoms) independent of covariates and independent of each other.Conclusion: This study showed that the use of mobile phones for calling and for sending text messages after lights out is associated with sleep disturbances among Japanese adolescents. However, there were some limitations, such as small effect sizes, in this study. More studies that examine the details of this association are necessary to establish strategies for sleep hygine in the future.

DOI： 10.5665/SLEEP.1152

Physical Activity in the Context of Clustering Patterns of Health-Promoting Behaviors 査読

Satoshi Tsuboi, Takehito Hayakawa, Hideyuki Kanda, Tetsuhito Fukushima

AMERICAN JOURNAL OF HEALTH PROMOTION 25 ( 6 ) 410 - 416 2011年7月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：AMER JOURNAL HEALTH PROMOTION INC

Purpose. To describe differences in physical activity in the context of clustering patterns of health-promoting behaviors.
Design. A cross-sectional study with 1 724 participants (response rate, 91.1%).
Setting. Tadami Town, in a rural area of Fukushima Prefecture, japan.
Subjects. Part of the general population who participated in annual health checkups (age range, 30-93 years).
Measures. The Health-Promoting Lifestyle Profile II was used to assess frequency of health-promoting behaviors (physical activity, health responsibility, spiritual growth, interpersonal relationships, nutrition, and stress management). Smoking status, alcohol consumption, and disease status were self reported. Public health nurses measured the weight and height of participants.
Analysis. Cluster analysis was conducted to identify clustering patterns of health-promoting behaviors other than physical activity. Differences in. physical activity between identified clusters were examined by multiple logistic regression analysis.
Results. Four clusters were identified and labeled as "Most challenged" (20.4%), "Adherence to norms" (30.3 %), "Well in mentality" (20.9%), and "Health-promoting" (28.4%). "Health-promoting" was the most physically active cluster, followed by "Adherence to norms" and "Well in mentality."
Conclusions. Although the survey methodology was subject to selection, self-report, and recall biases, we have described physical activity in the context of clustering patterns of health-promoting behaviors. Laying the groundwork for physical activity in the lifestyle is important for establishing health-promotion strategies to increase physical activity. (Am J Health Promot 2011;25 [6]:410-416.)

DOI： 10.4278/ajhp.090720-QUAN-232

Serum vitamins and heavy metals in blood and urine, and the correlations among them in parkinson's disease patients in China

Tetsuhito Fukushima, Xiaodong Tan, Yunwen Luo, Hideyuki Kanda

Neuroepidemiology 36 ( 4 ) 240 - 244 2011年7月

記述言語：英語掲載種別：研究論文（学術雑誌）

Background: Some heavy metals are suspected to be pathogenic and some vitamins protective against Parkinson's disease (PD), and the interaction between heavy metals and vitamins could be associated with the pathophysiology of PD. Methods: Subjects comprised PD patients and sex-and age-matched controls recruited from an outpatient clinic in China. Morning blood and urine samples were used to measure concentrations of metals and vitamins. Results: The serum iron, whole-blood manganese, urine iron and copper levels were significantly higher in the PD patients than in the controls. The correlation coefficient between serum and urine concentrations of iron in the PD patients was significant. The serum vitamin E/urine copper ratio was significantly lower in the PD patients than in the controls. Serum vitamin E was negatively correlated with serum copper and was positively correlated with urine copper in the PD patients. Serum vitamin B12 was positively correlated with serum zinc in the PD patients and was negatively correlated with urine zinc in the controls. Conclusions: Excessive intake of iron and copper, accumulation of manganese, vitamin E/copper imbalance in intake, and vitamin B12 decrease by zinc deficiency in the body might be involved in the etiology of PD. © 2011 S. Karger AG, Basel.

DOI： 10.1159/000328253

Scopus

Age verification cards fail to fully prevent minors from accessing tobacco products

Hideyuki Kanda, Yoneatsu Osaki, Takashi Ohida, Yoshitaka Kaneita, Takeshi Munezawa

TOBACCO CONTROL 20 ( 2 ) 163 - 165 2011年3月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：B M J PUBLISHING GROUP

Background Proper age verification can prevent minors from accessing tobacco products. For this reason, electronic locking devices based on a proof-of age system utilising cards were installed in almost every tobacco vending machine across Japan and Germany to restrict sales to minors.Objective We aimed to clarify the associations between amount smoked by high school students and the usage of age verification cards by conducting a nationwide cross-sectional survey of students in Japan.Methods This survey was conducted in 2008. We asked high school students, aged 13-18 years, in Japan about their smoking behaviour, where they purchase cigarettes, if or if not they have used age verification cards, and if yes, how they obtained this card.Results As the amount smoked increased, the prevalence of purchasing cigarettes from vending machines also rose for both males and females. The percentage of those with experience of using an age verification card was also higher among those who smoked more. Somebody outside of family was the top source of obtaining cards. Surprisingly, around 5% of males and females belonging to the group with highest smoking levels applied for cards themselves.Conclusions Age verification cards cannot fully prevent minors from accessing tobacco products. These findings suggest that a total ban of tobacco vending machines, not an age verification system, is needed to prevent sales to minors.

DOI： 10.1136/tc.2010.036947

Nightmare and sleep paralysis among Japanese adolescents: A nationwide representative survey

Takeshi Munezawa, Yoshitaka Kaneita, Yoneatsu Osaki, Hideyuki Kanda, Tadahiro Ohtsu, Hiroyuki Suzuki, Masumi Minowa, Kenji Suzuki, Susumu Higuchi, Junichirou Mori, Takashi Ohida

SLEEP MEDICINE 12 ( 1 ) 56 - 64 2011年1月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：ELSEVIER SCIENCE BV

Objective: The objective of this study was to clarify the prevalence of nightmares and sleep paralysis and associated factors among Japanese adolescents.Methods: This study was designed as a cross-sectional sampling survey. The targets were junior and senior high schools throughout Japan. Self-reported anonymous questionnaires were sent to schools for all students to complete.Results: A total of 90,081 questionnaires were analyzed. The overall response rate was 62.6%, and the prevalence of nightmares and sleep paralysis was 35.2% and 8.3%, respectively. Multiple logistic analyses revealed that female sex, drinking alcohol, poor mental health, difficulty initiating sleep, low subjective sleep assessment, presence of excessive daytime sleepiness, and presence of sleep paralysis had higher odds ratios than others for nightmares. Male sex, poor mental health, drinking alcohol, taking a long daytime nap, early or late bedtime, difficulty initiating sleep, low subjective sleep assessment, presence of excessive daytime sleepiness, and presence of nightmares had higher odds ratios than other factors for sleep paralysis.Conclusions: This study has revealed the prevalence of nightmares and sleep paralysis among Japanese adolescents. Furthermore, the results of this study suggest that it is important to maintain regular sleep habits for preventing these symptoms. We propose that health education about regular sleep habits should be promoted among Japanese adolescents. (C) 2010 Elsevier B.V. All rights reserved.

DOI： 10.1016/j.sleep.2010.04.015

Clarification of the factor structure of the 12-item General Health Questionnaire among Japanese adolescents and associated sleep status. 査読

Suzuki H, Kaneita Y, Osaki Y, Minowa M, Kanda H, Suzuki K, Wada K, Hayashi K, Tanihata T, Ohida T

Psychiatry Research 188 138-146 2011年1月

Fasting Plasma Insulin is Associated with Metabolic Syndrome in Farmers but not in Nomads among the Mongolian Population, China 査読

Hideyuki Kanda, Peiyu Wang, Tomonori Okamura, GaoWa Wuyun, HePing Wu, Xiulan Su, Takehito Hayakawa, Kenji Amamoto, Hirotsugu Ueshima

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS 18 ( 4 ) 291 - 297 2011年

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：JAPAN ATHEROSCLEROSIS SOC

Aim: The World Health Organization (WHO) includes insulin resistance among its criteria for diagnosing metabolic syndrome (MetS); however, previous epidemiologic studies have limited their research to settled populations only. This study aims to clarify the relationship between plasma insulin and metabolic factors on a broader scale by studying data obtained from nomadic and settled Mongolian populations.
Methods: A cross-sectional epidemiologic study of 200 nomads and 256 farmers was performed in Inner Mongolia, Republic of China. Plasma insulin levels and other metabolic factors, such as blood pressure, serum lipids and obesity, were measured. Participants were classified into 3 categories according to their plasma insulin levels.
Results: Cut-off values grouped into tertiles of fasting insulin for all participants were 6.73 nmol/L and 10.33 nmol/L. The mean number of metabolic risk factors, waist circumference, fasting plasma glucose and triglyceride were higher, and the mean HDL cholesterol was lower in the higher fasting insulin tertile among farmers after adjusting for age, gender, smoking, alcohol drinking and total cholesterol. However, no MetS factors were statistically related with fasting insulin tertile levels among nomads.
Conclusions: In nomads, hyperinsulinemia may not be an indicator of MetS due to their specific lifestyle.

DOI： 10.5551/jat.5843

Excessive daytime sleepiness and sleep behavior among Japanese adolescents: A nation-wide representative survey

Yoshitaka Kaneita, Takeshi Munezawa, Hiroyuki Suzuki, Tadahiro Ohtsu, Yoneatsu Osaki, Hideyuki Kanda, Masumi Minowa, Kenji Suzuki, Tetsuo Tamaki, Junichirou Mori, Ryuichirou Yamamoto, Takashi Ohida

SLEEP AND BIOLOGICAL RHYTHMS 8 ( 4 ) 282 - 294 2010年10月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：WILEY-BLACKWELL

Although a number of previous studies have examined the prevalence of excessive daytime sleepiness (EDS) among adolescents, there have been very few nationwide studies. Therefore, we conducted a cross-sectional nationwide study to clarify the prevalence of EDS and associated factors among Japanese adolescents. The survey was performed from December 2007 to March 2008 on students enrolled in randomly selected junior and senior high schools throughout Japan, using self-administered questionnaires. Of 90 361 questionnaires collected, 87 233 were analyzed. The Japanese version of the Epworth Sleepiness Scale (JESS) was used to measure EDS, which was defined as a JESS score of > 10. The prevalence (and 95% confidence interval) of EDS among males was 28.1% (27.7-28.5%), and that among females was 38.4% (37.9-38.9%). Multivariate analysis revealed that female sex, higher school grade, poor assessment of subjective sleep, late bedtime, parasomnia symptoms, long commuting time, poor mental health, drinking alcohol, smoking, and participating in extracurricular activities had significantly higher odds ratios for EDS. In conclusion, EDS in Japanese adolescents is common and associated with multiple factors.

DOI： 10.1111/j.1479-8425.2010.00474.x

Medical expenditures of men with hypertension and/or a smoking habit: a 10-year follow-up study of National Health Insurance in Shiga, Japan. 査読国際誌

Nakamura K, Okamura T, Hayakawa T, Kanda H, Okayama A, Ueshima H

Hypertens Res 33 ( 8 ) 802 - 807 2010年8月

Prevalence of and Factors Associated with Smoking among Japanese Medical Students

Tetsuo Tamaki, Yoshitaka Kaneita, Takashi Ohida, Eise Yokoyama, Yoneatsu Osaki, Hideyuki Kanda, Shinji Takemura, Kenji Hayashi

JOURNAL OF EPIDEMIOLOGY 20 ( 4 ) 339 - 345 2010年7月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：ELSEVIER SCIENCE INC

Background: The aim of the present study was to determine the prevalence of and factors associated with smoking among Japanese medical students, to help promote effective antismoking measures in this population.Methods: From the 80 university medical schools in Japan, 20 were randomly selected and invited to participate in our survey. The survey focused on medical students and employed an anonymous self-administered questionnaire. Information on each university's antismoking measures was obtained using a separate questionnaire administered to teaching stall The survey was conducted from December 2006 through March 2007. Factors associated with smoking were identified by using the chi-square test and multiple logistic regression analysis.Results: A total of 1619 valid surveys were returned. The overall prevalence of smoking was 13.7% (18.1% among men and 5.1% among women). Factors associated with smoking among medical students were male sex, enrollment at a private medical university, smoking by siblings, alcohol consumption, coffee consumption, insomnia, and less than 6 hours of sleep per night.Conclusions: Antismoking education must be further promoted to Japanese medical students, with consideration given to the factors associated with smoking behavior found in the present study.

DOI： 10.2188/jea.JE20090127