Faculty Profiles - KANDA Hideyuki

Papers - KANDA Hideyuki

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Risk factors of falls in inpatients and their practical use in identifying high-risk persons at admission: Fukushima Medical University Hospital cohort study. International journal

Takehito Hayakawa, Shigeatsu Hashimoto, Hideyuki Kanda, Noriko Hirano, Yumi Kurihara, Takako Kawashima, Tetsuhito Fukushima

BMJ open 4 ( 8 ) e005385 2014

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVES: To clarify the risk factors for falls in hospital settings and to propose the use of such factors to identify high-risk persons at admission. DESIGN: Prospective cohort study. SETTING: Fukushima Medical University Hospital, Japan, from August 2008 and September 2009. PARTICIPANTS: 9957 adult consecutive inpatients admitted to our hospital. METHODS: Information was collected at admission from clinical records obtained from a structured questionnaire conducted in face-to-face interviews with subjects by nurses and doctors and fall events were collected from clinical records. RESULTS: The proportion of patients who fell during follow-up was 2.5% and the incidence of falls was 3.28 per 100 person-days. There were significant differences in age, history of falling, cognitive dysfunction, planned surgery, wheelchair use, need for help to move, use of a remote caring system, rehabilitation, use of laxative, hypnotic or psychotropic medications and need for help with activities of daily living (ADL) between patients who did and did not fall. Multivariable adjusted ORs for falls showed that age, history of falls and need for help with ADL were common risk factors in both men and women. Using psychotropic medication also increased the risk of falling in men while cognitive dysfunction and use of hypnotic medication increased the risk of falling in women. Planned surgery was associated with a low risk of falls in women. CONCLUSIONS: To prevent falls in inpatients it is important to identify high-risk persons. Age, history of falling and the need for help with ADL are the most important pieces of information to be obtained at admission. Care plans for patients including fall prevention should be clear and considered.

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Associations between sleep disturbance and alcohol drinking: A large-scale epidemiological study of adolescents in Japan. International journal

Hisayoshi Morioka, Osamu Itani, Yoshitaka Kaneita, Maki Ikeda, Shuji Kondo, Ryuichiro Yamamoto, Yoneatsu Osaki, Hideyuki Kanda, Susumu Higuchi, Takashi Ohida

Alcohol (Fayetteville, N.Y.) 47 ( 8 ) 619 - 28 2013.12

Language：English Publishing type：Research paper (scientific journal)

In this study, we attempted to clarify the associations between various sleep disturbance symptoms and the frequency and amount of alcohol use among Japanese adolescents. This study was designed as a cross-sectional sampling survey. A self-administered questionnaire survey was administered to students enrolled in randomly selected junior and senior high schools throughout Japan. A total of 99,416 adolescents responded, and 98,867 questionnaires were subjected to analysis. The prevalence rates of sleep disturbance in the 30 days preceding the day of the survey were as follows: subjectively insufficient sleep (SIS) (boys: 37.6%, girls: 38.7%); short sleep duration (SSD) with less than 6 h of sleep (boys: 28.0%, girls: 33.0%); difficulty initiating sleep (DIS) (boys: 12.5%, girls: 14.1%); difficulty maintaining sleep (DMS) (boys: 10.1%, girls: 10.9%); and early morning awakening (EMA) (boys: 5.1%, girls: 5.0%). Adolescents reporting one or more symptoms of DIS, DMS, and EMA were classified as having insomnia, and its prevalence was 21.5%. The prevalence of each symptom of sleep disturbance increased significantly with the number of days on which alcohol was consumed in the previous 30 days and the amount of alcohol consumed per drinking session (p < 0.01). Multiple logistic regression analyses showed that the adjusted odds ratio (AOR) for each symptom of sleep disturbance, except SIS and EMA, tended to increase with the number of days on which alcohol was consumed and the amount of alcohol consumed per drinking session. The prevalence of sleep disturbance is particularly high among adolescents drinking alcohol. The risk of having each symptom of sleep disturbance, except SIS and EMA, increases with the number of days on which alcohol was consumed and the amount of alcohol consumed per drinking session. These findings reconfirm the need to eliminate underage drinking to ensure good sleep among adolescents.

DOI： 10.1016/j.alcohol.2013.09.041

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Call for action for setting up an infectious disease control action plan for disaster area activities: learning from the experience of checking suffering volunteers in the field after the Great East Japan Earthquake.

Kenzo Takahashi, Mitsuya Kodama, Hideyuki Kanda

Bioscience trends 7 ( 6 ) 294 - 5 2013.12

Language：English

After the Great East Japan Earthquake on March 11th, 2011, a journalist visited the disaster area with febrile symptoms and was diagnosed with measles of the D genotype, which is not indigenous to Japan. After continuing activities in disaster areas and Tokyo, 11 measles cases were reported, some of which were identified as genotype D. Meanwhile non-profit activities directed towards volunteers were offered including interviews to screen for subjective symptoms, check body temperature and advise volunteers to refrain from working in shelter areas during the period of sickness. As a consequence, disease transmission was controlled among volunteers. In disaster areas, anyone can be an infection vector. In order to prevent transmission of infectious diseases, a field action plan, which includes body temperature checks and standard precautions should be formulated and put into place. If the action plans are shared among local governments and non-governmental organizations (NGOs), they can become a norm and be expected to control infectious disease transmission.

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国際的な質問票を用いた高校職員全国調査による学校での喫煙対策の実態

神田秀幸, 高橋謙造, 菅谷渚, 水嶋春朔

日本公衆衛生学会総会抄録集 72回 342 - 342 2013.10

Comparing acquisition of radiation health knowledge and preventive behavior of working adults during and after the Fukushima disaster. International journal

Hideyuki Kanda, Kenzo Takahashi, Shunsaku Mizushima, Kikuo Koyama

Disaster medicine and public health preparedness 7 ( 4 ) 431 - 2 2013.8

Disorders of arousal and sleep-related bruxism among Japanese adolescents: a nationwide representative survey. International journal

Osamu Itani, Yoshitaka Kaneita, Maki Ikeda, Shuji Kondo, Ryuichiro Yamamoto, Yoneatsu Osaki, Hideyuki Kanda, Kenji Suzuki, Susumu Higuchi, Takashi Ohida

Sleep medicine 14 ( 6 ) 532 - 41 2013.6

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: The main objective of our study was to clarify the prevalence of disorders of arousal (confusional arousals, sleepwalking, sleep terrors) and sleep-related bruxism (teeth grinding) and their associated factors among Japanese adolescents. METHODS: Our study was designed as a cross-sectional sampling survey. The targets were students attending junior and senior high schools throughout Japan. The questionnaire asked for personal data and information on lifestyle, depressive state, and sleep status including the frequency of experiencing disorders of arousal and sleep-related bruxism. RESULTS: A total of 99,416 adolescents responded. The overall response rate was 63.7%, and 98,411 questionnaires were subjected to analysis. The prevalence of disorders of arousal was 7.1% (95% confidence interval [CI], 6.9-7.3%) among boys and 7.7% (95% CI, 7.5-7.9%) among girls. The prevalence of sleep-related bruxism was 2.3% (95% CI, 2.2-2.4%) among boys and 3.0% (95% CI, 2.8-3.2%) among girls. The factors associated with disorders of arousal were the grade in school, smoking habit, alcohol consumption, naptime (min), breakfast habit, participation in club activities, sleep duration, difficulty initiating sleep, nocturnal awakening, early morning awakening, subjective sleep assessment, snoring, decrease in positive feelings, and depression (all p<.001). The factors associated with sleep-related bruxism were gender, smoking habit, nocturnal awakening, snoring, early morning awakening, decrease in positive feelings, and depressive feelings (all p<.001). CONCLUSIONS: If disorders of arousal or sleep-related bruxism are observed in an adolescent, his or her smoking habit, alcohol consumption, sleep status, and depressive state should be considered.

DOI： 10.1016/j.sleep.2013.03.005

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中高生の授業中の居眠りと睡眠習慣に関する疫学研究

池田真紀, 兼板佳孝, 山本隆一郎, 井谷修, 近藤修治, 鈴木健二, 樋口進, 尾崎米厚, 神田秀幸, 大井田隆

日本睡眠学会定期学術集会プログラム・抄録集 38回 241 - 241 2013.6

わが国の中学生・高校生におけるいびきの経験頻度とその関連要因について

井谷修, 兼板佳孝, 池田真紀, 近藤修治, 山本隆一郎, 尾崎米厚, 神田秀幸, 鈴木健二, 樋口進, 大井田隆

日本睡眠学会定期学術集会プログラム・抄録集 38回 241 - 241 2013.6

Growing concerns with the flow of misinformation from electronic books. International journal

Kenzo Takahashi, Hideyuki Kanda, Shunsaku Mizushima

Interactive journal of medical research 2 ( 1 ) e10 2013.5

Language：English Publishing type：Research paper (scientific journal)

In 2012, several kinds of electronic books (e-books) became available in Japan. Since several major book retailers launched e-book businesses, it is expected that e-books will become a popular source of information in the country. However, we are concerned that e-books may also be a source of misinformation. In examining 24 available materials published by anti-vaccinists, "atopy businesses", and "wellness maintenance" authors, each was found to contain inaccuracies or misinformation. Thus far, such information is only available in printed books. If these books are scanned and circulated, or published in e-book format, this misinformation may circulate rapidly as e-book devices are becoming popular, and, consequently, harm people's health. We think that it is important for the government to formulate ethical guidelines for the publishing e-books with due consideration to freedom of expression.

DOI： 10.2196/ijmr.2541

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南ブラジル日系永住者におけるBMI、尿中食塩排泄量の血圧との関係

鳥羽直弥, 水嶋春朔, 高橋謙造, 神田秀幸, 根本明宜, 山末耕太郎, 森口エミリオ秀幸, 杤久保修

日本循環器病予防学会誌 48 ( 2 ) 132 - 132 2013.5

Preventive behaviours against radiation and related factors among general workers after Fukushima's nuclear disasters. Reviewed International journal

Hideyuki Kanda, Takehito Hayakawa, Kikuo Koyama

Emergency medicine journal : EMJ 30 ( 4 ) 287 - 91 2013.4

Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: The nuclear power plant accidents in Fukushima resulted in a widespread release of radioactive substances in the Fukushima prefecture. AIM: To clarify what factors led to precautions among general workers who displayed preventive behaviours against radiation following the nuclear disasters in Fukushima. METHODS: Descriptive study of preventive behaviours among general workers 3-5 months following the nuclear disasters. The subjects were 1394 regular workers who took part in radiation seminars conducted by the Fukushima Occupational Health Promotion Center between July and August 2011. Of 1217 responses, 1110 eligible responses were included in this study. This anonymous questionnaire survey was asking for characteristics and questions on preventive behaviours following the nuclear disasters. The authors assessed the contribution of each variable by a logistic regression analysis. RESULTS: Keeping track of environmental radiation levels and washing hands and gargling were significantly more frequent among female subjects, older age and workers residing up to approximately 80 km away from the power plants. Washing hands and gargling were also related with living with children. Wearing a mask when leaving home and buying bottled water were significantly more often observed with female subjects and workers residing up to 80 km. Refraining from going outdoors was positively associated with workers residing up to 80 km and workers living with children. CONCLUSIONS: These results provide information that may help with the targeting of health information after a nuclear disaster. This may contribute to determining an order of priority when distributing information after a nuclear disaster.

DOI： 10.1136/emermed-2011-201000

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What factors are associated with premature death among professional baseball players in Japan?

KANDA, Hideyuki, TSUBOI, Satoshi, TSUJI, Masayoshi, KAKAMU, Takeyasu, MORI, Yayoi, HAYAKAWA, Takehito, FUKUSHIMA, Tetsuhito

Health 5 ( 4 ) 757 - 760 2013.4

Differences in rates of decrease of environmental radiation dose rates by ground surface property in Fukushima City after the Fukushima Daiichi nuclear power plant accident. International journal

Takeyasu Kakamu, Hideyuki Kanda, Masayoshi Tsuji, Daisuke Kobayashi, Masao Miyake, Takehito Hayakawa, Shin-ichiro Katsuda, Yayoi Mori, Toshiyasu Okouchi, Akihiro Hazama, Tetsuhito Fukushima

Health physics 104 ( 1 ) 102 - 7 2013.1

Language：English Publishing type：Research paper (scientific journal)

After the Great East Japan Earthquake on 11 March 2011, the environmental radiation dose in Fukushima City increased. On 11 April, 1 mo after the earthquake, the environmental radiation dose rate at various surfaces in the same area differed greatly by surface property. Environmental radiation measurements continue in order to determine the estimated time to 50% reduction in environmental radiation dose rates by surface property in order to make suggestions for decontamination in Fukushima. The measurements were carried out from 11 April to 11 November 2011. Forty-eight (48) measurement points were selected, including four kinds of ground surface properties: grass (13), soil (5), artificial turf (7), and asphalt (23). Environmental radiation dose rate was measured at heights of 100 cm above the ground surface. Time to 50% reduction of environmental radiation dose rates was estimated for each ground surface property. Radiation dose rates on 11 November had decreased significantly compared with those on 11 April for all surface properties. Artificial turf showed the longest time to 50% reduction (544.32 d, standard error: 96.86), and soil showed the shortest (213.20 d, standard error: 35.88). The authors found the environmental radiation dose rate on artificial materials to have a longer 50% reduction time than that on natural materials. These results contribute to determining an order of priority for decontamination after nuclear disasters.

DOI： 10.1097/HP.0b013e31826ab94c

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Heavy metals in blood and urine and its relation to depressive symptoms in Parkinson's disease patients.

Tetsuhito Fukushima, Xiaodong Tan, Yunwen Luo, Puqing Wang, Jinhui Song, Hideyuki Kanda, Takehito Hayakawa, Tomohiro Kumagai, Takeyasu Kakamu, Masayoshi Tsuji, Tomoo Hidaka, Yayoi Mori

Fukushima journal of medical science 59 ( 2 ) 76 - 80 2013

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVES: Some heavy metals are suspected to be pathogenic to both Parkinson's disease (PD) and depression. Common background may exist in them. METHODS: Subjects comprised PD patients with depression, PD patients without depression and controls recruited from the outpatient clinic in China. Morning blood and urine samples were used to measure concentrations of metals and vitamins. RESULTS: Whole-blood manganese was significantly higher in the PD patients without depression than in both the PD patients with depression and the controls. Serum iron was significantly higher in the PD patients without depression than in the controls. Urine iron was also significantly higher in the PD patients without depression than in the controls. Serum copper was significantly lower in the PD patients with depression than in both the PD patients without depression and the controls. CONCLUSIONS: Excessive intake of iron and accumulation of manganese seemed to be involved in the etiology of non-depressive PD.

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General workers living with younger children in Fukushima performed more preventive behavior against radiation during and after the nuclear disaster. International journal

Hideyuki Kanda, Nagisa Sugaya, Kenzo Takahashi, Shunsaku Mizushima, Kikuo Koyama

Asian Pacific journal of cancer prevention : APJCP 14 ( 11 ) 6893 - 7 2013

Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: During and after the Fukushima nuclear disaster (FND), many parents were concerned about the effects of radiation on the health of their children. PURPOSE: To clarify the factors that influenced general workers living with children and the effect of child age groups in implementing preventive behaviorsagainst radiation following the FND. MATERIALS AND METHODS: A descriptive study of preventive behaviors among general workers was carried out 3-5 months after the nuclear disaster. The subjects were 1,394 regular workers, who took part in radiation seminars run by the Fukushima Occupational Health Promotion Center between July and September, 2011. In total, 1,217 responses were submitted, of which 1,110 were eligible for the present study. This anonymous questionnaire survey inquired about the presence and age of children in the household and about radiation preventive behavior implemented after the FND. The contribution of each variable was assessed by logistic regression analysis. RESULTS: General workers in Fukushima who lived with younger children performed more preventive behavior against radiation during and after the FND. In particular, both location-related and daily routines were practiced significantly more frequently (p<0.01) by workers living with a child in the age ranges of 0-6 (8 of 10 items) and 7-12 (5 of 10 items). CONCLUSIONS: This is the first study to assess the positive association between living with children by age group and increased preventive behavior against radiation implemented by general workers after the FND.

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[Worker heat disorders at the Fukushima Daiichi nuclear power plant].

Masayoshi Tsuji, Takeyasu Kakamu, Takehito Hayakawa, Tomohiro Kumagai, Tomoo Hidaka, Hideyuki Kanda, Tetsuhito Fukushima

Sangyo eiseigaku zasshi = Journal of occupational health 55 ( 2 ) 53 - 8 2013

Language：Japanese Publishing type：Research paper (scientific journal)

OBJECTIVES: Ever since the Fukushima Daiichi nuclear power plant (NPP) accident, every day about 3,000 workers have been working to repair the situation. The frequent occurrence of heat disorders has been a concern for the workers wearing protective clothing with poor ventilation. We have been analyzing the heat disorder problem since the accident in order to come up with a solution to prevent future heat disorder incidents among Fukushima Daiichi NPP accident clean-up workers. METHODS: From March 22 to September 16, 2011, the Fukushima Labor Bureau assessed 43 cases of nuclear power plant workers with heat disorders. Age of subject, month and time of occurrence, temperature, and humidity were examined for each case, as well as the severity of heat disorders. The grade of severity was divided into Grade I and Grade II or higher. Then, age, temperature, and humidity were analyzed using the Mann-Whitney Utest, and age, temperature, humidity, and presence or absence of a cool-vest were analyzed using the χ(2) test and logistic regression analysis. SPSS version 17.0 statistical software was used with a level of significance of p< 0.05. RESULTS: Heat disorders occurred most frequently in subjects in their 40s (30.2%), followed by those in their 30s (25.6%), mostly in July (46.5%) between 7 am and 12 pm (69.8%). Heat disorders occurred most frequently in environments with temperatures more than 25°C (76.7%) and humidity of 70-80% (39.5%). Heat disorders of Grade II or higher occurred in 10 cases, 5 of which were in June. According to statistical analysis, there were no significant differences in difference of severity for all factors. CONCLUSIONS: Heat disorders usually occur in workers aged 45-60; however, cases of heat disorders at the Fukushima Daiichi NPP occurred in clean-up workers at the relatively younger ages of 30-40, suggesting the need for heat disorder prevention measures for these younger workers. Heat disorder cases primarily occurred in the morning, necessitating preventive measures for the early hours of the day. In addition, because heat disorders of Grade II or higher occurred in June in 5 of 10 cases, we believe heat disorder precautions should be implemented from June. The lack of significant difference in severity difference may be attributable to the small number of cases or other factors. We think Fukushima Daiichi NPP accident clean-up workers need heat disorder prevention measures for their safety, based on the results of this study.

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The economic and medical costs of alcohol consumption in Japan Reviewed

H. Kanda, T. Okamura

West Indian Medical Journal 62 ( 9 ) 785 - 786 2013

Japan's vaccine service and an introduction to the history of cumulative vaccine coverage Reviewed

Kenzo Takahashi, Hideyuki Kanda

Journal of Antivirals and Antiretrovirals 5 ( 6 ) 151 - 153 2013

Language：English Publishing type：Research paper (scientific journal)

During the measles epidemic periods in 1999-2003, a research group elaborated a method of estimating vaccination coverage. The objective of cumulative vaccination coverage (CVC) was to estimate the age of vaccine completion for vaccine targets in an age cohort. From randomly selected children of an age cohort, vaccine records including the date of birth and date of vaccine administration were retrieved, allowing for the calculation of the age of vaccine targets. By acquiring this information, it is possible to derive vaccination trends by age. According to the literature, CVC is now more widely applied and is used for monitoring delays of vaccination due to changes of the vaccine administration schedule and schedule interaction when newly-introduced vaccines are implemented. Although CVC is rather costly because it requires random sampling, we conclude that it is a useful method for estimating herd immunity. © 2013 Takahashi K, et al.

DOI： 10.4172/jaa.1000080

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未成年者の喫煙行動と不眠の関連性に関する疫学研究

城戸尚治, 兼板佳孝, 尾崎米厚, 谷畑健生, 神田秀幸, 大井田隆

日大医学雑誌 71 ( 6 ) 428 - 435 2012.12

Language：Japanese Publisher：日本大学医学会

全国約10万人の中高生を対象とした大規模疫学調査データを用いて喫煙行動と不眠の関連性について検討を行った。調査デザインは断面標本調査とした。2004年から2005年にかけて全国学校総覧より無作為抽出した中学高校の在校生を対象に自記式質問調査票による調査を行い、回答に不備のなかった102,451人分の調査票を解析した。入眠障害、中途覚醒、早朝覚醒の有訴者率は、喫煙日数、喫煙本数が多いあるいはニコチン依存度が高いほど有意に高値を示した。多重ロジスティック回帰分析により非喫煙者に対する調整オッズ比を算出した結果、毎日喫煙する、1日21本以上喫煙する、朝起きていつもすぐに吸いたくなるという群が最も高値を示し、いずれも有意な関連が認められた。これら体内のニコチン摂取量と不眠症状の関係から、喫煙行動と不眠の間に密接な関連があることが示唆された。今後、学校において喫煙防止と睡眠衛生を含めた包括的な対策が必要である。(著者抄録)

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Other Link： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2012&ichushi_jid=J01010&link_issn=&doc_id=20130125470014&doc_link_id=10.4264%2Fnuma.71.428&url=https%3A%2F%2Fdoi.org%2F10.4264%2Fnuma.71.428&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_3.gif

東日本大震災および原子力災害経験者からみた福島の子供を取り巻く環境

神田秀幸, 高橋謙造, 水嶋春朔

神奈川県公衆衛生学会誌 ( 58 ) 50 - 50 2012.11

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Papers - KANDA Hideyuki