Faculty Profiles - KANDA Hideyuki

Papers - KANDA Hideyuki

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Factors Associated with Return of Spontaneous Circulation in Outof Hospital Cardiopulmonary Arrest Cases. Reviewed

Funo Y, Taniguchi E, Taniura H, Yoshioka M, Kanda H, Sano C

Shimane Journal of Medical Science 38 ( 1 ) 23 - 31 2021.4

Effect of Coronavirus Disease 2019 Pandemic on Physical Activity in a Rural Area of Japan: The Masuda Study Reviewed

Takashi Hisamatsu, Kaori Taniguchi, Mari Fukuda, Minako Kinuta, Noriko Nakahata, Hideyuki Kanda

Journal of Epidemiology 31 ( 3 ) 237 - 238 2021.3

トラックドライバーへの健康支援に関する運行管理者の役割～関わりと困難感～ Reviewed

島本さと子, 錦戸典子, 神田秀幸, 三橋祐子

日本職業・災害医学会会誌 69 ( 2 ) 65 - 75 2021.3

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：(一社)日本職業・災害医学会

【目的】トラックドライバーの健康支援のため、運行管理者によるドライバーへの健康支援に繋がる関わりや健康支援上の困難感の調査を行った。【対象・方法】運送業の事業主・運行管理者向けのセミナー参加者へ無記名自記式調査票を配布・回収(482人、回収率62.2%)した。分析対象はそのうちの現任運行管理者163人を選んだ。調査内容は、(1)基本属性(11項目)(2)会社の方針や体制(8項目)(3)マニュアルや相談窓口の活用(4項目)(4)健康支援に繋がる関わりの程度(16項目)(5)健康支援上の困難感(9項目)だった。分析では、まず(4)(5)の項目毎の平均得点を算出した。次に従業員規模と健康診断等担当の兼務の有無等でKruskal-Wallis、Mann-WhitneyのU検定(P<.05)で項目別回答分布の違いを確認した。また従業員規模50人未満かつ、産業保健スタッフなし群を抽出し健康相談窓口の活用度と困難感の関連を確認した。【結果】"健康支援に繋がる関わり"はいずれも平均点が高めで、「日頃から雑談をし、ねぎらいの言葉をかけるなど運転者と様々なコミュニケーションをとっている」(3.4±0.5)が最も高値だった。"健康支援上の困難感"もいずれも平均得点が高めで、最も高値は「運転者の体調確認や健康支援を、極め細やかに行う時間や人手が不足している」(3.2±0.9)だった。健診等の担当の兼務あり群では"健康支援に繋がる関わり"で有意に高い項目が6項目あった。従業員規模50人未満かつ、産業保健スタッフなし群では公的健康相談窓口を3割が「知らない」と答え、「知らない」群では人手不足とメンタルヘルスに関する項目で困難感が有意に高かった。【結論】運行管理者は健康支援に繋がる関わりを多くもち、ドライバーの健康支援のキーパーソンといえる。また健診等の担当の兼務者は、非兼務者より健康支援がやり易いことも示唆された。今後さらなる専門家や社外資源の活用にむけ教育・支援が重要と考えられた。(著者抄録)

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The association between problematic internet use and neck pain among Japanese schoolteachers International journal

Rina Tanabe, Takashi Hisamatsu, Mari Fukuda, Hideki Tsumura, Rina Tsuchie, Masako Suzuki, Nagisa Sugaya, Koshi Nakamura, Kenzo Takahashi, Hideyuki Kanda

Journal of Occupational Health 63 ( 1 ) 12298 2021.1

Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Wiley

OBJECTIVES: Problematic internet use (PIU) has been suggested in relation to psychological symptoms among schoolteachers, but the relationship with physical symptoms remains unclear. We examined whether PIU or longer Internet usage time is associated with neck pain in schoolteachers. METHODS: We conducted a cross-sectional study among 2582 teachers aged 20 years or older (35.6% women) in Shimane and Tottori, Japan in 2018. Neck pain was defined as ≥5 points on the Neck Disability Index. The Compulsive Internet Use Scale (CIUS) was used to assess PIU. Internet usage time on weekdays and weekends was divided into five groups: 0, 1-29, 30-59, 60-119, and ≥120 min/day. Logistic regression analysis was conducted to examine the association of the CIUS score and Internet usage time on weekdays or weekends with neck pain, adjusting for sex, age, position at school, insomnia, and psychological distress. RESULTS: We observed 800 (31.0%) teachers with neck pain. The median (interquartile range) of their CIUS scores was 7 (2, 14). A higher CIUS score was independently associated with a higher prevalence of neck pain (odds ratio of 4th vs. 1st quartiles, 1.41; 95% confidence interval, 1.06-1.87; trend P = .006). Compared with non-Internet users, Internet users on weekdays had almost double the odds of neck pain although the difference did not reach the customary level for designating statistical significance. CONCLUSIONS: In conclusion, teachers with higher scores in CIUS were associated with a higher prevalence of neck pain in Japan, suggesting adults with PIU being at risk of physical disorders.

DOI： 10.1002/1348-9585.12298

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Other Link： https://onlinelibrary.wiley.com/doi/full-xml/10.1002/1348-9585.12298

Effectiveness of Screening and Brief Alcohol Intervention at the Workplace: A Study Protocol for a Randomized Controlled Trial at Five Japan-Based Companies Reviewed

Yuki Kuwabara, Aya Kinjo, Maya Fujii, Ruriko Minobe, Hitoshi Maesato, Susumu Higuchi, Hisashi Yoshimoto, Maki Jike, Yuichiro Otsuka, Osamu Itani, Yoshitaka Kaneita, Hideyuki Kanda, Yoneatsu Osaki

Yonago Acta Medica 2021

Pregnancy by Assisted Reproductive Technology Is Associated with Shorter Telomere Length in Neonates Reviewed

Toshiko Minamoto, Kentaro Nakayama, Tomoka Ishibashi, Masako Ishikawa, Kohei Nakamura, Hitomi Yamashita, Kamrunnahar Shanta, Hossain Mohammad Mahmud, Sultana Razia, Kouji Iida, Gyosuke Sakashita, Tsukasa Nakamura, Hideyuki Kanda, Satoru Kyo

International Journal of Molecular Sciences 21 ( 24 ) 9688 - 9688 2020.12

Language：English Publishing type：Research paper (scientific journal) Publisher：MDPI AG

Telomere length (TL) influences the development of lifestyle-related diseases, and neonatal TL may influence their prevalence. Various factors have been reported to affect neonatal TL. Although the fetus is exposed to multiple conditions in utero, the main factors affecting the shortening of neonatal TL are still not known. In this study, we sought to identify factors that influence fetal TL. A total of 578 mother-newborn pairs were included for TL analysis. TL was measured in genomic DNA extracted from cord blood samples using quantitative PCR. The clinical factors examined at enrollment included the following intrauterine environmental factors: maternal age, assisted reproductive technology (ART) used, body mass index (BMI), gestational diabetes mellitus (GDM), maternal stress, smoking, alcohol consumption, preterm delivery, small-for-gestational-age, neonatal sex, and placental weight. Univariate and multivariate regression analyses were used to verify the relationship between neonatal TL and these clinical factors. The median neonatal TL to single-copy gene ratio was 1.0. Pregnancy with ART was among the 11 factors associated with shorter neonatal TL. From multiple regression analysis, we determined that neonatal TL was significantly shorter for pregnancies in the ART group than in the other groups. We conclude that pregnancy with ART is associated with shorter neonatal TL.

DOI： 10.3390/ijms21249688

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Gender differences in dietary behaviors among Japanese adolescents. Reviewed International journal

Yuichiro Otsuka, Yoshitaka Kaneita, Osamu Itani, Maki Jike, Yoneatsu Osaki, Susumu Higuchi, Hideyuki Kanda

Preventive medicine reports 20 101203 - 101203 2020.12

Authorship：Last author Language：English Publishing type：Research paper (scientific journal)

Unhealthy dietary behaviors in adolescence are an important public health problem. Gender differences in dietary behaviors have already appeared during adolescence. However, few studies have assessed a variety of adolescent dietary behaviors in Japan. We aimed to clarify gender differences in unhealthy dietary behaviors among Japanese adolescents. The participants consisted of 84,988 participants from seventh to 12th grades. Unhealthy dietary behaviors were defined according to the National Health and Nutrition Survey. Multivariable logistic regression was used to analyze a nationally representative sample of Japanese adolescents from the 2014 to 2015 Lifestyle Survey. The effective response rate was 51.4%. The prevalence of unhealthy dietary behaviors (skipping breakfast, snacking, eating out, skipping meals, eating alone at dinner, and subjectively poor diet quality) among boys and girls was 14.2% versus 12.4%, 19.6% versus 14.1%, 10.6% versus 7.0%, 7.9% versus 5.6%, 13.3% versus 12.1%, and 12.3% versus 15.8%, respectively. Compared with boys, girls were more negatively associated with skipping breakfast [OR = 0.76 (95% CI 0.73-0.79)], snacking [OR = 0.67 (95% CI 0.65-0.70)], eating out [OR = 0.62 (95% CI 0.59-0.66)], skipping meals [OR = 0.61 (95% CI 0.58-0.65)], and eating alone at dinner [OR = 0.79 (95% CI 0.76-0.83)]. However, girls were more positively associated with subjectively poor diet quality [OR = 1.19 (95% CI 1.14.1.24)]. The findings suggest that gender differences existed in dietary behaviors. Gender differences in dietary behaviors suggest opportunities for tailoring interventions related to dietary education in schools.

DOI： 10.1016/j.pmedr.2020.101203

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Isolated systolic hypertension and 29-year cardiovascular mortality risk in Japanese adults aged 30--49 years. Reviewed International journal

Takashi Hisamatsu, Katsuyuki Miura, Takayoshi Ohkubo, Aya Kadota, Keiko Kondo, Yoshikuni Kita, Takehito Hayakawa, Hideyuki Kanda, Tomonori Okamura, Akira Okayama, Hirotsugu Ueshima

Journal of hypertension 38 ( 11 ) 2230 - 2236 2020.11

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: The prognostic implication of isolated systolic hypertension (ISH), defined as SBP at least 140 mmHg and DBP less than 90 mmHg, among young-to-middle-aged adults remains controversial. We examined the association of ISH with cardiovascular disease (CVD) risk in adults aged 30-49 years. METHODS: In a prospective cohort of representative Japanese general populations from the NIPPON DATA80 (1980-2009), we studied 4776 participants (mean age, 39.4 years; 55.4% women) without clinical CVD or antihypertensive medication. Participants were classified as follows: normal blood pressure (BP) (SBP/DBP, <120/<80 mmHg), high-normal BP (120-129/<80 mmHg), elevated BP (130-139/80-89 mmHg), ISH, isolated diastolic hypertension (IDH) (<140/≥90 mmHg), and systolic--diastolic hypertension (SDH) (≥140/≥90 mmHg). RESULTS: ISH was observed in 389 (8.1%) participants. During the 29-year follow-up, 115 participants died of CVD, 28 of coronary heart disease, and 49 of stroke. Cox proportional hazards models adjusted for demographics and CVD risk factors showed that participants with ISH had higher risk of CVD mortality than those with normal BP [hazard ratio (confidence interval), 4.10 (1.87-9.03)]. The magnitude of CVD mortality risk related to ISH was comparable with that related to IDH [3.38 (1.31-8.72)] and not as great as that related to SDH [5.41 (2.63-11.14)]. We found significant associations of ISH with coronary and stroke mortality. The association of ISH with CVD mortality was consistent across men and women and those aged 30-39 and 40-49 years. CONCLUSION: ISH among young-to-middle-aged Japanese adults was independently associated with higher risk of CVD mortality later in life.

DOI： 10.1097/HJH.0000000000002533

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Association between Psychological Factors and Evacuation Status and the Incidence of Cardiovascular Diseases after the Great East Japan Earthquake: A Prospective Study of the Fukushima Health Management Survey

Toshiki Sanoh, Eri Eguchi, Tetsuya Ohira, Fumikazu Hayashi, Masaharu Maeda, Seiji Yasumura, Yuriko Suzuki, Hirooki Yabe, Atsushi Takahashi, Kanae Takase, Mayumi Harigane, Takashi Hisamatsu, Keiki Ogino, Hideyuki Kanda, Kenji Kamiya

International Journal of Environmental Research and Public Health 17 ( 21 ) 7832 - 7832 2020.10

Publishing type：Research paper (scientific journal) Publisher：MDPI AG

Evidence regarding the effect of psychological factors and evacuation on cardiovascular disease occurrence after large-scale disasters is limited. This prospective study followed up a total of 37,810 Japanese men and women aged 30–89 years from the Fukushima Prefecture with no history of stroke or heart disease at baseline (2012), until 2017. This period included 3000 cardiovascular events recorded through questionnaires and death certificates. The participants’ psychological distress, trauma reaction, and evacuation status were defined, and divided into four groups based on combinations of psychological factors and evacuation status. We calculated the hazard ratios and 95% confidence intervals for only psychological, only evacuation, or both of them compared with neither using Cox proportional hazard models. Psychological factors along with evacuation resulted in approximately 5% to 25% higher magnitude of stroke and heart disease risk than psychological factors only among men. Compared to neither, the multivariable hazard ratios of those with both psychological distress and evacuation were 1.75 for stroke and 1.49 for heart disease, and those of both trauma reaction and evacuation were 2.01 and 1.57, respectively, among men. Evacuation combined with psychological factors increased the risk of stroke and heart disease risks especially in men after the Great East Japan Earthquake.

DOI： 10.3390/ijerph17217832

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産業保健の現場における減酒支援ブリーフインターベンションの効果検証に関する研究

桑原祐樹, 金城文, 尾崎米厚, 藤井麻耶, 美濃部るり子, 真栄里仁, 吉本尚, 大塚雄一郎, 井谷修, 兼板佳孝, 地家真紀, 神田秀幸

日本公衆衛生学会総会抄録集 79回 245 - 245 2020.10

地域住民におけるJSH2019にもとづく高血圧の有病率・認知率・治療率・管理率益田研究

久松隆史, 福田茉莉, 谷口かおり, 宮川健, 中畑典子, 神田秀幸

日本公衆衛生学会総会抄録集 79回 339 - 339 2020.10

全国高校eスポーツ選手権大会出場校の実態

神田秀幸, 田邉莉奈, 福田茉莉, 久松隆史

日本アルコール・薬物医学会雑誌 55 ( 5 ) 90 - 90 2020.10

日本の中学・高校教員におけるインターネット依存と頸部痛のリスクの関連

田邉莉奈, 久松隆史, 福田茉莉, 土江梨奈, 鈴木雅子, 菅谷渚, 中村幸志, 高橋謙造, 神田秀幸

日本アルコール・薬物医学会雑誌 55 ( 5 ) 95 - 95 2020.10

Heat-not-burn tobacco, electronic cigarettes, and combustible cigarette use among Japanese adolescents: a nationwide population survey 2017. International journal

Yuki Kuwabara, Aya Kinjo, Maya Fujii, Aya Imamoto, Yoneatsu Osaki, Maki Jike, Yuichiro Otsuka, Osamu Itani, Yoshitaka Kaneita, Ruriko Minobe, Hitoshi Maezato, Susumu Higuchi, Hisashi Yoshimoto, Hideyuki Kanda

BMC public health 20 ( 1 ) 741 - 741 2020.5

Authorship：Last author Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: From among the global public health concerns, smoking remains one of the most crucial challenges. Especially for adolescents, the increase in the use of electronic cigarettes is controversial, as its use may lead to established smoking. In Japan, where a unique tobacco regulation system exists, the heat-not-burn tobacco market has been growing. However, the prevalence and association of combustible cigarettes and new tobacco-related products have not yet been closely investigated among Japanese adolescents. This study aimed to clarify the prevalence of smoking among adolescents, including new types of tobacco-related products, and to compare the characteristics of their users. METHODS: The 2017 Lifestyle Survey of Adolescents is a nationally-representative survey collected in Japan. From the national school directory, 98 junior high schools and 86 high schools were randomly sampled throughout Japan. The students completed an anonymous questionnaire at school. We calculated the prevalence of use for each type of tobacco product. Then, the use of a combination of products and the characteristics of different types of products were examined. RESULTS: In total, 64,152 students from 48 junior high schools and 55 high schools were included the analysis (school response rate = 56%, Mage = 15.7 years, 53.9% boys). The age-adjusted rate of ever (current) use of electronic cigarettes was 2.1% (0.7%) in junior high school and 3.5% (1.0%) in high school; that of combustible cigarettes was 2.6% (0.6%) in junior high school and 5.1% (1.5%) in high school. The rate of heat-not-burn tobacco use was lower relative to other products: 1.1% (0.5%) in junior high school and 2.2% (0.9%) in high school. An examination of the combined use of the three products identified a high number of dual users. Comparisons between different types of users indicated different backgrounds for combustible cigarette users and new product users. CONCLUSIONS: The prevalence of new tobacco-alternative products is growing in popularity among Japanese adolescents. Dual use is common, and many adolescents use new products only. Moreover, e-cigarettes might attract a broader range of groups to smoking. Continuous monitoring and research are needed to investigate their influence as a possible gateway to tobacco smoking.

DOI： 10.1186/s12889-020-08916-x

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The relationship between subjective happiness and sleep problems in Japanese adolescents. International journal

Yuichiro Otsuka, Yoshitaka Kaneita, Osamu Itani, Maki Jike, Yoneatsu Osaki, Susumu Higuchi, Hideyuki Kanda, Aya Kinjo, Yuki Kuwabara, Hisashi Yoshimoto

Sleep medicine 69 120 - 126 2020.5

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVES: Low sleep quality in adolescents is an important public health concern, as it relates to both their current and future physical and mental health. Furthermore, subjective happiness is also often regarded as a major life goal. Although Japan is an economically powerful country, the reported levels of subjective happiness among Japanese adolescents is low. Thus, this study aims to examine the relationship between subjective happiness and sleep problems in Japanese adolescents. METHODS: We conducted a nationally representative cross-sectional study of adolescents enrolled in junior and senior high schools in Japan. We used a questionnaire to determine the prevalence of sleep problems (eg, insomnia, short sleep duration (SSD) and poor sleep quality) and to evaluate the participants' reported levels of subjective happiness. Multivariable logistic regression analyses were used to examine the associations between subjective happiness and sleep problems. Adjusted variables were basic demographic characteristics (eg, gender and school grade), lifestyle behaviors, and mental health status. RESULTS: Data from 64,329 students were analyzed (age range 12-18 years, mean age 15.7 years, 53.9% male). The results indicated that reported levels of subjective happiness were strongly associated with the prevalence of sleep problems. Linear relationships can be observed between sleep problems and subjective happiness scores. The multivariable logistic regression analysis showed that dose-response association of subjective happiness score was observed with all three sleep problems. CONCLUSIONS: Due to these findings, we recommend that policy makers and school officials educate adolescents on the importance of both subjective happiness and good sleep hygiene.

DOI： 10.1016/j.sleep.2020.01.008

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トラック運送業における運行管理者による健康支援普段の関わりと困難点(第二報)

島本さと子, 錦戸典子, 神田秀幸, 三橋祐子

産業衛生学雑誌 62 ( 臨増 ) 569 - 569 2020.5

Factors and impact of physicians' diagnostic errors in malpractice claims in Japan. Reviewed International journal

Takashi Watari, Yasuharu Tokuda, Shohei Mitsuhashi, Kazuya Otuki, Kaori Kono, Nobuhiro Nagai, Kazumichi Onigata, Hideyuki Kanda

PloS one 15 ( 8 ) e0237145 2020

Authorship：Last author Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: Diagnostic errors are prevalent and associated with increased economic burden; however, little is known about their characteristics at the national level in Japan. This study aimed to investigate clinical outcomes and indemnity payment in cases of diagnostic errors using Japan's largest database of national claims. METHODS: We analyzed characteristics of diagnostic error cases closed between 1961 and 2017, accessed through the national Japanese malpractice claims database. We compared diagnostic error-related claims (DERC) with non-diagnostic error-related claims (non-DERC) in terms of indemnity, clinical outcomes, and factors underlying physicians' diagnostic errors. RESULTS: All 1,802 malpractice claims were included in the analysis. The median patient age was 33 years (interquartile range = 10-54), and 54.2% were men. Deaths were the most common outcome of claims (939/1747; 53.8%). In total, 709 (39.3%, 95% CI: 37.0%-41.6%) DERC cases were observed. The adjusted total billing amount, acceptance rate, adjusted median claims payments, and proportion of deaths were significantly higher in DERC than non-DERC cases. Departments of internal medicine and surgery were 1.42 and 1.55 times more likely, respectively, to have DERC cases than others. Claims involving the emergency room (adjusted odds ratio [OR] = 5.88) and outpatient office (adjusted OR = 2.87) were more likely to be DERC than other cases. The initial diagnoses most likely to lead to diagnostic error were upper respiratory tract infection, non-bleeding digestive tract disease, and "no abnormality." CONCLUSIONS: Cases of diagnostic errors produced severe patient outcomes and were associated with high indemnity. These cases were frequently noted in general exam and emergency rooms as well as internal medicine and surgery departments and were initially considered to be common, mild diseases.

DOI： 10.1371/journal.pone.0237145

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Skipping breakfast, poor sleep quality, and Internet usage and their relation with unhappiness in Japanese adolescents. Reviewed International journal

Yuichiro Otsuka, Yoshitaka Kaneita, Osamu Itani, Maki Jike, Yoneatsu Osaki, Susumu Higuchi, Hideyuki Kanda, Aya Kinjo, Yuki Kuwabara, Hisashi Yoshimoto

PloS one 15 ( 7 ) e0235252 2020

Language：English Publishing type：Research paper (scientific journal)

Subjective happiness is often regarded as a major life goal. Although Japan is an economically powerful country, the level of subjective well-being reported among Japanese adolescents is lower than in other countries. We aimed to investigate the lifestyle factors related to unhappiness in Japanese adolescents. We collected data through the 2017-2018 Lifestyle Survey of Adolescents, a nationally representative cross-sectional study enrolled in randomly selected junior and senior high schools throughout Japan. We assessed the prevalence of subjective unhappiness in junior and senior high school students according to school life factors and daily lifestyle habits. A multivariable logistic regression analysis was used to examine the associations between these factors and unhappiness. A total of 64,329 students were included in the sample (mean age 15.7 years, 53.9% boys). The average prevalence of unhappiness was 10.2%. The logistic regression analyses indicated that unhappiness was strongly associated with being male and with engaging in unhealthy lifestyle behaviors such as not having breakfast, poor sleep quality, and some problematic Internet usage. Although the prevalence of unhappiness was significantly higher among current smokers and alcohol drinkers, these behaviors were not associated with unhappiness in the multivariable logistic regression analysis. Unhappiness among Japanese adolescents appears to be strongly related to how they spend their daily life. We therefore consider it desirable for school officials to educate students on the importance of happiness and lifestyle factors conducive to happiness.

DOI： 10.1371/journal.pone.0235252

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島根県における血圧管理状況の現状とその課題 Reviewed

岡達郎, 牧野由美子, 大城等, 谷口栄作, 神田秀幸

島根医学 39 ( 3 ) 134 - 140 2019.12

山陰地方における公立学校の労働衛生管理体制の現状と課題

鈴木雅子, 津村秀樹, 福田茉莉, 土江梨奈, 菅谷渚, 中村幸志, 高橋謙造, 神田秀幸

日本公衆衛生学会総会抄録集 78回 402 - 402 2019.10

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