研究者詳細 - 田邊　俊介

MISC - 田邊　俊介

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局所進行食道癌・胃癌に対する内視鏡外科の手術手技【Video】気管前リンパ節転移、心膜T4症例に対する胸腔鏡下食道切除術

前田直見, 白川靖博, 赤井正明, 西江尚貴, 田辺俊介, 櫻間教文, 野間和広, 楳田祐三, 西崎正彦, 香川俊輔, 藤原俊義

日本外科学会定期学術集会抄録集 120回 WS - 8 2020年8月

病的肥満症に対する腹腔鏡下スリーブ状胃切除術導入と初期10例の治療成績

香川俊輔, 黒田新士, 菊地覚次, 高田暢夫, 庄司良平, 西崎正彦, 寺石文則, 近藤喜太, 矢野修也, 重安邦俊, 野間和広, 田辺俊介, 白川靖博, 藤原俊義

日本外科学会定期学術集会抄録集 120回 DP - 5 2020年8月

癌微小環境が引き起こす腫瘍免疫抑制の解明 "Drug repositioning"による免疫応答賦活化の可能性

西脇紀之, 野間和広, 赤井正明, 小林照貴, 鳴坂徹, 河本慧, 加藤卓也, 前田直見, 田辺俊介, 大原利章, 田澤大, 白川靖博, 藤原俊義

日本外科学会定期学術集会抄録集 120回 SF - 4 2020年8月

Skeletal muscle loss in the postoperative acute phase after esophageal cancer surgery as a new prognostic factor. 査読国際誌

Naoaki Maeda, Yasuhiro Shirakawa, Shunsuke Tanabe, Kazufumi Sakurama, Kazuhiro Noma, Toshiyoshi Fujiwara

World journal of surgical oncology 18 ( 1 ) 143 - 143 2020年6月

記述言語：英語

BACKGROUND: The postoperative survival rate of patients with esophageal squamous cell carcinoma (ESCC) remains poor compared with other gastrointestinal cancers. We hypothesized that skeletal muscle loss in the postoperative acute phase might be a new predictor for long-term prognosis after highly invasive surgery such as ESCC surgery. METHODS: The following items were retrospectively investigated. First, whether skeletal muscle loss occurred in the postoperative acute phase of ESCC was verified. Second, the preoperative and intraoperative factors involved in skeletal muscle loss in the postoperative acute phase of ESCC were investigated. Then, whether skeletal muscle loss in the postoperative acute phase affected long-term prognosis was examined. The medical records of consecutive patients who underwent radical esophagectomy for ESCC between January 2010 and February 2015 were retrospectively reviewed; 72 cases were eligible for this study. The total psoas major muscle mass index (TPI) at the level of the third lumbar vertebra (L3) was measured using computed tomography (CT) before surgery and 3 days after surgery. The long-term prognosis was estimated by the Kaplan-Meier method and the multivariate logistic regression model. RESULTS: There was already a significant reduction of TPI in the acute phase up to POD 3 after ESCC surgery in comparison with the preoperative baseline TPI (P < 0.001). The TPI reduction rate was significantly milder in cases with less blood loss during surgery and in cases that underwent thoracoscopic esophagectomy than in cases that underwent open esophagectomy. The 3-year overall survival rate was significantly different between the TPI reduction rate severe group and the TPI reduction rate mild group. CONCLUSION: Skeletal muscle loss occurred even in the postoperative acute phase. Furthermore, it is very significant that skeletal muscle loss in the postoperative acute phase of ESCC surgery is involved in the long-term prognosis.

DOI： 10.1186/s12957-020-01908-6

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横隔膜上食道憩室に対して胸腔鏡下憩室切除術を施行した1例

久松加寿也, 白川靖博, 赤井正明, 西江尚貴, 前田直見, 田辺俊介, 野間和広, 櫻間教文, 藤原俊義

日本臨床外科学会雑誌 81 ( 6 ) 1202 - 1202 2020年6月

Intraoperative fluid therapy and postoperative complications during minimally invasive esophagectomy for esophageal cancer: a single-center retrospective study. 査読

Yukiko Hikasa, Satoshi Suzuki, Yuko Mihara, Shunsuke Tanabe, Yasuhiro Shirakawa, Toshiyoshi Fujiwara, Hiroshi Morimatsu

Journal of anesthesia 34 ( 3 ) 404 - 412 2020年6月

記述言語：英語

PURPOSE: Compared with open thoracotomy, minimally invasive esophagectomy (MIE) methods, such as transhiatal or thoracoscopic esophagectomy, likely have lower morbidity. However, the relationship between intraoperative fluid management and postoperative complications after MIE remains unclear. Thus, we investigated the association of cumulative intraoperative fluid balance and postoperative complications in patients undergoing MIE. METHODS: This single-center retrospective cohort study examined patients undergoing thoracoscopic esophagectomy for esophageal cancer in the prone position. Postoperative complications included pneumonia, arrhythmia, thrombotic events and acute kidney injury (AKI). We compared patients with higher and lower intraoperative fluid balance (higher and lower than the median). Multivariable logistic regression analyses were performed to estimate the odds ratio of intraoperative fluid balance status on the incidence of postoperative complications. RESULTS: In total, 135 patients were included in the study. Postoperative complications occurred in 43 (32%), including cardiac arrhythmia (n = 12, 9%), thrombosis (n = 20, 15%), pneumonia (n = 13, 10%), and AKI required hemodialysis (n = 1, 1%). Patients with a higher fluid balance had higher incidence of complications than those with a lower fluid balance (46% vs. 18%, p < 0.001). After adjusting for age, ASA-PS ≥ III, blood loss, and the use of radical surgery, the higher intraoperative fluid balance group was significantly and independently associated with postoperative complications (adjusted OR 5.31, 95% CI 2.26-13.6, p < 0.0001). CONCLUSIONS: In patients undergoing thoracoscopic esophagectomy in the prone position, a greater intraoperative positive fluid balance was independently associated with a higher incidence of complications.

DOI： 10.1007/s00540-020-02766-y

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Surgical site infection caused by Aeromonas hydrophila presenting as necrotizing soft tissue infection after esophagectomy. 査読国際誌

Osamu Yamasaki, Eizo Takahashi, Kazuyo Noda, Nobuhiko Kanaya, Shunsuke Tanabe, Yasuhiro Shirakawa, Shin Morizane

The Journal of dermatology 47 ( 6 ) 673 - 676 2020年6月

記述言語：英語

Several virulence factors of Aeromonas such as hemolysin, proteases and lipases have been characterized. The relationship between these virulence factors and disease remains unclear. A 71-year-old man underwent thoracoscopic esophagectomy, lymph node dissection and Roux-en-Y reconstruction for esophageal cancer. On postoperative day 1, redness around the wound on the thoracic abdominal wall gradually enlarged and necrosis became apparent with septic shock. Necrotizing soft tissue infection was suspected and emergency surgical debridement was performed. Blood and wound cultures were positive for Aeromonas hydrophila. The strain was found to have hemolytic activity, proteolytic activity and extremely high elastolytic activity. In addition, the strain actively produced elastolytic metalloprotease, which may contribute to extensive tissue necrosis.

DOI： 10.1111/1346-8138.15323

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【術前・術後管理必携2020】術式別術前・術後管理食道胸部食道癌手術

田辺俊介, 白川靖博

消化器外科 43 ( 5 ) 603 - 607 2020年4月

Induction chemoradiotherapy including docetaxel, cisplatin, and 5-fluorouracil for locally advanced esophageal cancer. 査読

Masashi Hashimoto, Yasuhiro Shirakawa, Naoaki Maeda, Shunsuke Tanabe, Kazuhiro Noma, Kazufumi Sakurama, Kuniaki Katsui, Masahiko Nishizaki, Toshiyoshi Fujiwara

Esophagus : official journal of the Japan Esophageal Society 17 ( 2 ) 127 - 134 2020年4月

記述言語：英語

BACKGROUND: Locally advanced esophageal cancer (EC) invading surrounding organs (T4b) is difficult to treat. In general, definitive chemoradiotherapy (d-CRT) has been chosen as treatment for such cases. However, the outcome has not been good. Recently, the effectiveness of d-CRT with docetaxel, cisplatin, and 5-fluorouracil (DCF-RT) has been reported. Furthermore, surgery after d-CRT has a better prognosis than d-CRT alone in some reports, although it has a high risk of surgical complications. This study investigated the effectiveness and safety of induction DCF-RT. METHODS: The subjects were EC patients who underwent induction DCF-RT in Okayama University Hospital between January 2011 and December 2017. Their background characteristics, treatment details, histopathological factors, adverse events during CRT, postoperative complications, and overall survival (OS) were assessed. RESULTS: A total of 16 cases were performed induction DCF-RT. In 10 cases, death occurred, with 9 cancer-related deaths, and 1 death due to other disease. For all cases, OS was 37.5% at 3 years. 12 cases underwent esophagectomy after DCF-RT. Their OS was 50% at 3 years. 13 patients (81.3%) had Grade 3 febrile neutropenia. In 7 cases (62.5%), fasting for the treatment of diarrhea was needed. Three patients (25%) developed anastomotic leakage. Some recurrent laryngeal nerve paralysis was observed in 6 cases (50%). CONCLUSION: Although the rates of adverse events and surgical complications were slightly higher than in past reports, they were acceptable. It is useful to perform induction DCF-RT for T4b EC.

DOI： 10.1007/s10388-019-00709-5

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食道癌患者に対する腫瘍融解ウイルスの内視鏡的投与の実際病棟実施にむけた他部署連携

矢野朋美, 采女典子, 森隆弘, 笠原由美子, 石川貴子, 田辺俊介, 黒田新士, 野間和広, 田澤大, 香川俊輔, 白川靖博, 藤原俊義

日本消化器内視鏡技師会会報 ( 64 ) 111 - 112 2020年3月

術前SOX療法を施行した進行胃癌症例の治療成績(Outcomes of preoperative S-1 plus oxaliplatin(SOX) therapy for advanced gastric cancer)

香川俊輔, 黒田新士, 菊地覚次, 高田暢夫, 垣内慶彦, 武田正, 野間和広, 田辺俊介, 寺石文則, 近藤喜太, 矢野修也, 重安邦俊, 西崎正彦, 白川靖博, 藤原俊義

日本胃癌学会総会記事 92回 288 - 288 2020年3月

術前SOX療法を施行した進行胃癌症例の治療成績(Outcomes of preoperative S-1 plus oxaliplatin(SOX) therapy for advanced gastric cancer)

日本胃癌学会総会記事 92回 288 - 288 2020年3月

下顎切除した血糖コントロール不良の血液透析患者の栄養介入に難渋した一症例

今井祥子, 開原裕子, 高橋絢子, 長谷川祐子, 濱中麻矢, 大木晴美, 金聖暎, 日野隼人, 山本昌直, 村田尚道, 縄稚久美子, 菊地覚次, 田辺俊介, 四方賢一

日本病態栄養学会誌 23 ( Suppl. ) S - 56 2020年1月

神経疾患患者に対する多職種での関わり

今井祥子, 開原裕子, 長谷川祐子, 瀬戸山祐佳, 濱中麻矢, 金聖暎, 日野隼人, 名和秀起, 田尻絢子, 山本昌直, 村田尚道, 縄稚久美子, 水口真実, 菊地覚次, 田辺俊介, 宗淳一, 四方賢一

学会誌JSPEN 1 ( Suppl.2 ) 59 - 60 2020年1月

当院でのNSTと総合リハビリテーション部との関わり

森山裕美, 三宅裕高, 今井祥子, 長谷川祐子, 開原裕子, 内山慶子, 濱中麻矢, 岡野寛子, 金聖暎, 日野隼人, 田尻絢子, 村田尚道, 前田直見, 菊地覚次, 田辺俊介, 四方賢一

学会誌JSPEN 1 ( Suppl.2 ) 103 - 104 2020年1月

保存的に治癒し得た食道癌胸骨後経路再建術後に発症した胃管気管瘻の一例

西村星多郎, 白川靖博, 菅野令子, 光井恵麻, 國友知義, 前田直見, 田邊俊介, 野間和広, 櫻間教文, 藤原俊義

日本臨床外科学会雑誌 81 2020年

T4bに対する導入DCF-RT療法~高い局所制御率とその課題~

橋本将志, 白川靖博, 前田直見, 田邊俊介, 櫻間教文, 野間和広, 西崎正彦, 勝井邦彰, 藤原俊義

日本食道学会学術集会抄録集(CD-ROM) 74th 2020年

食道癌根治手術10年後に発症した肝転移を伴うStageIV胃管癌の一治療例

田辺俊介, 野間和広, 前田直見, 白川靖博, 藤原俊義

日本胸部外科学会定期学術集会(Web) 73rd 2020年

胃が使用不可能な場合の空腸を用いた食道再建の工夫

白川靖博, 野間和広, 前田直見, 田辺俊介, 櫻間教文, 藤原俊義

日本胸部外科学会定期学術集会(Web) 73rd 2020年

再手術症例から学ぶ形成外科的手技を用いた合併症回避のための術式の工夫

松本洋, 太田智之, 川本幸司, 木股敬裕, 白川靖博, 野間和広, 田邊俊介, 前田直見, 藤原俊義

日本食道学会学術集会抄録集(CD-ROM) 74th 2020年

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