Faculty Profiles - TANABE Shunsuke

MISC - TANABE Shunsuke

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食道胃接合部癌の治療戦略内視鏡治療から集学的治療まで当科における食道胃接合部癌の治療経験

野間和広, 白川靖博, 加藤卓也, 竹原清人, 前田直見, 田辺俊介, 西崎正彦, 香川俊輔, 藤原俊義

日本胃癌学会総会記事 87回 180 - 180 2015.3

食道癌術後再建胃管癌症例の検討

田辺俊介, 白川靖博, 賀島肇, 前田直見, 櫻間教文, 野間和広, 西崎正彦, 香川俊輔, 藤原俊義

日本胃癌学会総会記事 87回 302 - 302 2015.3

Prone-position thoracoscopic resection of posterior mediastinal lymph node metastasis from rectal cancer. Reviewed International journal

Yasuhiro Shirakawa, Kazuhiro Noma, Takeshi Koujima, Naoaki Maeda, Shunsuke Tanabe, Toshiaki Ohara, Toshiyoshi Fujiwara

World journal of surgical oncology 13 45 - 45 2015.2

Language：English

Mediastinal lymph node metastasis from colorectal cancer is rare, and barely any reports have described resection of this pathology. We report herein a successful thoracoscopic resection of mediastinal lymph node metastasis in a prone position. A 65-year-old man presented with posterior mediastinal lymph node metastasis after resection of the primary rectal cancer and metachronous hepatic metastasis. Metastatic lymph nodes were resected completely using thoracoscopic surgery in the prone position, which provided advantages of minimal invasiveness, good surgical field, and reduced ergonomic burden on the surgeon. Thoracoscopic resection in the prone position was thought to have the potential to become the standard procedure of posterior mediastinal tumors.

DOI： 10.1186/s12957-015-0466-0

PubMed

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【ERAS】ERASと周術期チーム医療

白川靖博, 加藤卓也, 竹原清人, 前田直見, 田辺俊介, 櫻間教文, 野間和広, 足羽孝子, 佐藤建治, 森松博史, 藤原俊義

外科 77 ( 2 ) 142 - 146 2015.2

Language：Japanese Publisher：(株)南江堂

ERASの実践のためには,医師だけでなく多職種のメディカルスタッフを交えたチーム医療の実践が不可欠である.当院ではERASプロトコルの多くを取り入れた周術期管理センター・ペリオ(perioperative management center:PERIO)が周術期チーム医療を行っている.組織横断的に情報を共有しながら業務を行うことにより,安全・安心な周術期環境の提供が可能となっている.(著者抄録)

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Other Link： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2015&ichushi_jid=J00393&link_issn=&doc_id=20150127150004&doc_link_id=issn%3D0016-593X%26volume%3D77%26issue%3D2%26spage%3D142&url=http%3A%2F%2Fwww.pieronline.jp%2Fopenurl%3Fissn%3D0016-593X%26volume%3D77%26issue%3D2%26spage%3D142&type=PierOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00005_2.gif

Viral transduction of the HER2-extracellular domain expands trastuzumab-based photoimmunotherapy for HER2-negative breast cancer cells. Reviewed International journal

Kyoko Shimoyama, Shunsuke Kagawa, Michihiro Ishida, Shinichiro Watanabe, Kazuhiro Noma, Kiyoto Takehara, Hiroshi Tazawa, Yuuri Hashimoto, Shunsuke Tanabe, Junji Matsuoka, Hisataka Kobayashi, Toshiyoshi Fujiwara

Breast cancer research and treatment 149 ( 3 ) 597 - 605 2015.2

Language：English

The prognosis of HER2-positive breast cancer has been improved by trastuzumab therapy, which features high specificity and limited side effects. However, trastuzumab-based therapy has shortcomings. Firstly, HER2-targeted therapy is only applicable to HER2-expressing tumors, which comprise only 20-25% of primary breast cancers. Secondly, many patients who initially respond to trastuzumab ultimately develop disease progression. To overcome these problems, we employed virus-mediated HER2 transduction and photoimmunotherapy (PIT) which involves trastuzumab conjugated with a photosensitizer, trastuzumab-IR700, and irradiation of near-infrared light. We hypothesized that the gene transduction technique together with PIT would expand the range of tumor entities suitable for trastuzumab-based therapy and improve its antitumor activity. The HER2-extracellular domain (ECD) was transduced by the adenoviral vector, Ad-HER2-ECD, and PIT with trastuzumab-IR700 was applied in the HER2-negative cancer cells. Ad-HER2-ECD can efficiently transduce HER2-ECD into HER2-negative human cancer cells. PIT with trastuzumab-IR700 induced direct cell membrane destruction of Ad-HER2-ECD-transduced HER2-negative cancer cells. Novel combination of viral transduction of a target antigen and an antibody-based PIT would expand and potentiate molecular-targeted therapy even for target-negative or attenuated cancer cells.

DOI： 10.1007/s10549-015-3265-y

PubMed

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Prone-Position Thoracoscopic Ligation of the Thoracic Duct for Chyle Leak Following Radical Neck Dissection in a Patient with a Right Aortic Arch. Reviewed

Yasuhiro Shirakawa, Kazuhiro Noma, Toshiaki Ohara, Hajime Kashima, Naoaki Maeda, Shunsuke Tanabe, Shunsuke Kagawa, Toshiyoshi Fujiwara

Acta medica Okayama 69 ( 3 ) 173 - 6 2015

Language：English

A chyle leak can occur as a complication after neck or chest surgery. Such a leak prolongs the hospital stay and is sometimes life-threatening. The treatment options are conservative management, interventional radiologic embolization, and surgery. Thoracoscopic ligation of the thoracic duct has emerged as a promising and definitive treatment. The case of a 65-year-old Japanese male patient with a rare congenital right aortic arch (typeⅢB1 of Edward's classification) and a severe chyle leak that occurred after a total pharyngolaryngo-esophagectomy (TPLE) is described. The chyle leak was successfully managed by thoracoscopic ligation of the thoracic duct via a left-side approach with the patient in the prone position.

PubMed

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食道胃接合部手術に対する胸腔内観音開き法再建の検討

加藤卓也, 野間和広, 竹原清人, 前田直見, 田邊俊介, 櫻間教文, 西崎正彦, 香川俊輔, 白川靖博, 藤原俊義

日本消化器外科学会雑誌(Web) 48 ( Supplement1 ) 2015

Operative technique of antethoracic esophageal reconstruction with pedicled jejunal flap

Yasuhiro Shirakawa, Kazuhiro Noma, Takeshi Koujima, Naoaki Maeda, Shunsuke Tanabe, Toshiaki Ohara, Kazufumi Sakurama, Toshiyoshi Fujiwara

ESOPHAGUS 12 ( 1 ) 57 - 64 2015

Language：English Publisher：SPRINGER JAPAN KK

Esophageal reconstruction using intestine is often performed for esophageal cancer patients in cases where the stomach cannot be used. We have previously performed reconstruction using ileocolon with supercharge and drainage as our first choice in those cases. However, a less invasive, simpler, and safer reconstructive technique using jejunum without vascular anastomosis has recently become popular at our facility. This study describes the technique of esophageal reconstruction with jejunum, compares the surgical outcomes to those of standard reconstruction using ileocolon, and discusses the clinical significance of this new concept.Subjects comprised 53 patients (52 males, 1 female) who underwent esophageal reconstruction using jejunum between January 2008 and July 2013. Patient characteristics, technical details, and outcomes were compared with those of 51 subjects who had undergone esophageal reconstruction using ileocolon. When making the pedicled jejunal flap, the first jejunal vascular arcade was preserved, which in most cases allowed it to be pulled up to the cervical region by processing and transection up to the second jejunal vascular branch.The vascular anastomosis techniques were used in 80.4 % (41/51) of esophageal reconstructions using colon, compared with only 24.5 % (13/53) of reconstructions using jejunum. No difference in the frequency of postoperative adverse effects was seen between groups, but the frequency of diarrhea was significantly lower with reconstruction using jejunum.Esophageal reconstruction using jejunum with the blood vessel processing technique results in both simpler and safer pulling up. Thus the need to perform supercharge and superdrainage is reduced.

DOI： 10.1007/s10388-014-0455-3

Web of Science

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内視鏡外科の低侵襲性を評価する腹臥位胸腔鏡下食道切除術の栄養学的評価の検討

白川靖博, 賀島肇, 前田直見, 田辺俊介, 櫻間教文, 野間和広, 藤原俊義

日本内視鏡外科学会雑誌 19 ( 7 ) 316 - 316 2014.10

Novel combination therapy of adenoviral gene transfer of HER2-extracellular domain and trastuzumab-based photoimmunotherapy for HER2 negative cancer cells Reviewed

Michihiro Ishida, Shunsuke Kagawa, Kyoko Shimoyama, Kiyoto Takehara, Kazuhiro Noma, Shunsuke Tanabe, Hiroshi Tazawa, Junji Matsuoka, Hisataka Kobayashi, Toshiyoshi Fujiwara

CANCER RESEARCH 74 ( 19 ) 2014.10

食道癌手術患者の術前胸郭拡張差についての基礎的検討

大原利章, 白川靖博, 國府島健, 前田直見, 田辺俊介, 野間和広, 岩井賢司, 伊藤真理, 足羽孝子, 藤原俊義

日本食道学会学術集会プログラム・抄録集 68回 99 - 99 2014.7

ウイルスを用いたHER2陰性胃癌の強制的HER2標識化とTrastuzumabによる分子標的光免疫療法

香川俊輔, 石田道拡, 田澤大, 下山京子, 竹原清人, 野間和広, 渡辺めぐみ, 田辺俊介, 小林久隆, 藤原俊義

日本消化器外科学会総会 69回 O - 4 2014.7

食道切除・再建術におけるリスク評価と治療成績向上に向けた対策食食道癌術前の呼吸機能管理目標設定とチーム介入の成果

大原利章, 白川靖博, 國府島健, 前田直見, 田辺俊介, 櫻間教文, 野間和広, 藤原俊義

日本消化器外科学会総会 69回 PD - 12 2014.7

頸部食道癌の治療戦略喉頭温存を目指して

國府島健, 白川靖博, 前田直見, 大原利章, 田辺俊介, 櫻間教文, 野間和広, 藤原俊義

日本食道学会学術集会プログラム・抄録集 68回 188 - 188 2014.7

食道癌手術における安全な吻合法空腸を用いた食道再建及び吻合の工夫全例に血管吻合が必要か?

白川靖博, 國府島健, 前田直見, 大原利章, 田辺俊介, 櫻間教文, 野間和広, 藤原俊義

日本消化器外科学会総会 69回 VSY - 8 2014.7

当科における食道胃接合部癌の経験および治療戦略

野間和広, 白川靖博, 国府島健, 前田直見, 大原利章, 田辺俊介, 西崎正彦, 香川俊輔, 藤原俊義

日本消化器外科学会総会 69回 O - 2 2014.7

cT1bN0M0 cStage I食道癌に対する外科治療についての検討

白川靖博, 國府島健, 前田直見, 田辺俊介, 大原利章, 櫻間教文, 野間和広, 藤原俊義

日本食道学会学術集会プログラム・抄録集 68回 83 - 83 2014.7

鏡視下手術導入と多職種組織横断的周術期管理による高齢者食道癌手術への取り組み

田辺俊介, 白川靖博, 國府島健, 前田直見, 大原利章, 櫻間教文, 野間和広, 藤原俊義

日本食道学会学術集会プログラム・抄録集 68回 78 - 78 2014.7

当科におけるバレット食道表在癌の治療経験

野間和広, 白川靖博, 国府島健, 前田直見, 大原利章, 田辺俊介, 西崎正彦, 香川俊輔, 藤原俊義

日本食道学会学術集会プログラム・抄録集 68回 176 - 176 2014.7

食道癌手術における歯科の役割

山中玲子, 曽我賢彦, 前田直見, 大原利章, 田辺俊介, 野間和広, 白川靖博, 森松博史, 藤原俊義

日本食道学会学術集会プログラム・抄録集 68回 145 - 145 2014.7

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