Faculty Profiles - MATSUMOTO Yosuke

MISC - MATSUMOTO Yosuke

Division display 101 - 119 of about 119 ／ All the affair displays >>

最近の学生における「体型に関する意識」調査

絹見佳子, 内藤恵子, 黒木清美, 今井あゆみ, 小林むつみ, 岩崎寿美, 高山直美, 松本洋輔, 松浦一陽, 小倉俊郎, 戸部和夫

第32回中国・四国大学保健管理研究集会報告書 2002

IV F13 Effects of YM872,a selective AMPA receptor antagonist, in the rat kindling model of epilepsy :

Hara Hiroshi, Yamada Norihito, Kodama Masazumi, Wake Yosuke, Matsumoto Yosuke, Sato Toshiki, Kuroda Shigetoshi

( 36 ) 277 - 277 2002

III G5 Dynamic changes of perineuronal nets of parvalbumin neurons in the developing hippocampus and after kainic acid convulsions. :

Matsumoto Yosuke, Sakiyama Junko, Mori Shuji, Yoshimune Shinji, Yamada Norihito, Okamoto Motoi

( 36 ) 249 - 249 2002

クエチアピンが著効した従来型抗精神病薬で副作用を呈しやすい治療抵抗性精神分裂病の２例

松本洋輔, 原田俊樹, 石野博志, 久山圭介, 高田広之進, 武南克子, 福場浩章, 大橋一予, 増山和彦, 大林正和

Pharma Medica 2001

A-27 深部前梨状葉皮質を焦点とした電気刺激発作重積モデルにおいて海馬のけいれん準備状態が亢進する

和気洋介, 北村吉宏, 山田了士, 小山文彦, 二宮庸太郎, 松本洋輔, 森本清, 黒田重利

日本てんかん学会プログラム・予稿集 ( 35 ) 113 - 113 2001

Characterization of epileptiform field potentials recorded in the in vitro perirhinal cortex of amygdala-kindled epileptogenesis

Yosuke Matsumoto, Norihito Yamada, Kiyoshi Morimoto, David K. Bilkey, Shigetoshi Kuroda

Brain Research 741 ( 1-2 ) 44 - 51 1996.11

Language：English

The perirhinal cortex (PRC) has recently been reported that the excitatory role of this area is important for the generation and the propagation of kindled seizures. In the present study, we investigated the extracellular electrophysiological properties of the circuitry which contribute to the propagation of seizures in the PRC, and examined the hypothesis that amygdala-kindling changes the electrophysiological nature of the rat PRC slice in vitro. Field potentials elicited in the PRC had extended duration (&gt
200 ms, most ≃ 1 s) with overlying spike components. The potentials showed strong synchronizing effect governed by an all-or-none rule. Although spontaneous epileptiform discharges that were equivalent in appearance to synaptically-activated field potentials were observed in the PRC of both amygdala-kindled and control rats, the number of slices showing spontaneous activity was significantly larger in the kindled group than in the control group (χ2-test, P &lt
0.01). The occurrence of tetanus-induced afterdischarges in kindled rats was significantly higher than in control rats (χ2-test, P &lt
0.01). The afterdischarge durations of control slices were generally short and the afterdischarges did not consist of the typical 'tonic-clonic' phases. However, the occurrence of the electrographical seizure in the high K+ ACSF were not affected by amygdala-kindling operation. These results indicate that amygdala-kindling lowers the threshold for transsynaptic excitability and enhances the synchronized activity of the PRC induced by episodic proconvulsive manipulations such as tetanus stimulation.

DOI： 10.1016/S0006-8993(96)00878-5

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Epileptic activity in the cat perirhinal cortex in response to amygdala kindling

ORITA AKIHISA, MORIWAKE TAKASHI, YAMADA NORIHITO, OTSUKI KENRO, NORIKIYO TAIZO, MATSUMOTO YOSUKE, MORIMOTO KIYOSHI, KURODA SHIGETOSHI

49 ( 3 ) S290 - S292 1995.6

B-1 側頭葉てんかんの脳血流定量SPECTおよび^<123>I-Iomazenil SPECTによる検討

則清泰造, 松本洋輔, 山田了士, 大月健郎, 佐藤俊樹, 三柳耕平, 折田暁尚, 黒田重利, 岡本基, 佐藤修平, 平木祥夫, 森本清

日本てんかん学会プログラム・予稿集 ( 29 ) 106 - 106 1995

Intractable epilepsy therapy development with experimental epilepsy kindling.( Sponsor : Ministry of Health and Welfare ).

森本清, 山田了士, 難波多鶴子, 佐藤圭子, 松本洋輔, 北村吉宏, 大月健郎, 則清泰造, 佐藤俊樹

難治てんかんの治療法開発に関する研究平成6年度研究報告書 49 - 52 1995

B-9 ネコキンドリングにおける刺激部位としての周嗅領皮質

折田暁尚, 山田了士, 森分隆, 三柳耕平, 大月健郎, 松本洋輔, 則清泰造, 佐藤俊樹, 黒田重利, 森本清

日本てんかん学会プログラム・予稿集 ( 29 ) 110 - 110 1995

C-22 扁桃核キンドリングによるネコ周嗅領皮質脳波活動の変化

折田暁尚, 山田了士, 森分隆, 大月健郎, 松本洋輔, 則清泰造, 佐藤俊樹, 黒田重利, 森本清

日本てんかん学会プログラム・予稿集 ( 28 ) 134 - 134 1994

A-18 側頭葉てんかんの123I-IMP動脈血持続採決法による脳血流定量SPECT評価

則清泰造, 松本洋輔, 山田了士, 佐藤俊樹, 大月健郎, 折田暁尚, 黒田重利, 岡本基, 佐藤修平, 平木祥夫, 森本清

日本てんかん学会プログラム・予稿集 ( 28 ) 93 - 93 1994

Anticonvulsant actions of a selective AMPA receptor antagonist, NBQX on amygdala kindled seizures in rats.

難波多鶴子, 森本清, 佐藤圭子, 清水幸登, 松本洋輔, 北村吉宏, 山田了士

Neurosciences 19 ( Suppl 1 ) 225 - 228 1993.4

Antiepileptogenic and anticonvulsant actions of an antagonist of strychnine-insensitive glycine receptors in the rat amygdala kindling model.

森本清, 難波多鶴子, 松本洋輔, 清水幸登, 北村吉宏, 山田了士, 黒田重利

精神薬療研究年報 ( 24(1992) ) 60 - 65 1993.3

NS-5 扁桃核キンドリングによるラット周嗅領皮質電気活動の変化 : スライス実験による検討

松本洋輔, 山田了士, 難波多鶴子, 大月健郎, 清水幸登, 北村吉宏, 森本清, 黒田重利

日本てんかん学会プログラム・予稿集 ( 27 ) 85 - 85 1993

2F-15 新しい抗てんかん薬Lamotrigineのラットキンドリング発作に対する抗けいれん効果

大月健郎, 佐藤圭子, 山田了士, 難波多鶴子, 清水幸登, 松本洋輔, 北村吉宏, 森本清

日本てんかん学会プログラム・予稿集 ( 27 ) 211 - 211 1993

2B-8 選択的AMPA受容体拮抗薬の抗けいれん作用 : I扁桃核および海馬キンドリング発作に対する効果

森本清, 難波多鶴子, 佐藤圭子, 大月健郎, 松本洋輔, 山田了士

日本てんかん学会プログラム・予稿集 ( 27 ) 176 - 176 1993

C-3 ラット梨状葉冠状断スライスにおけるてんかん性活動について

山田了士, 松本洋輔, 森本清, Bilkey David K, Dragunow Michael

日本てんかん学会プログラム・予稿集 ( 26 ) 122 - 122 1992

A Comparative Study of the Anticonvulsant Effect of GABA Agonists on Amygdala or Hippocampal Kindled Seizures in Cats

Morimoto Kiyoshi, Sanei Toshihumi, Sato Keiko, Shimizu Yukito, Matsumoto Yosuke, Namba Tazuko, Yamada Norihito

Journal of the Japan Epilepsy Society 10 ( 3 ) 268 - 278 1992

Language：Japanese Publisher：JAPAN EPILEPSY SOCIETY

A comparative study of the anticonvulsant effect of GABA agonists on amygdala or hippocampal kindled seizures was performed in cats. Progabide (GABA receptor agonist, 25-100mg/kg) significantly reduced both the kindled seizure stage and afterdischarge (AD) duration in a dose-dependent manner. SKF89976A (GABA re-uptake inhibitor, 0.25-2mg/kg) also significantly reduced kindled seizures. At a toxic dose of SKF89976A, induction of the AD in the kindled focus was completely suppressed, although it caused EEG spike and myoclonus. Furthermore, &gamma;-vinyl GABA (GVG: inhibitor of GABA transaminase, 50-200mg/kg) significantly reduced only the kindled seizure stage with the prolonged duration of ADs. In contrast, baclofen (selective GABA-B receptor agonist, 1 and 5mg/kg) did not show any anticonvulsant effects either on the seizure stage or on the AD duration. It is concluded that these GABA agonists, which potentiate the inhibitory function of the GABA-A system, have potent anticonvulsant effects on kindled seizures from the lymbic focus as well as secondary generalization in cats.

DOI： 10.3805/jjes.10.268

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