研究者詳細 - HARA EMILIO SATOSHI

論文 - HARA EMILIO SATOSHI

分割表示 97 件中 41 - 60 件目／全件表示 >>

Acidic Pre-Conditioning Enhances the Stem Cell Phenotype of Human Bone Marrow Stem/Progenitor Cells 査読

Yuri Hazehara-Kunitomo, Emilio S. Hara, Mitsuaki Ono, Kyaw Aung, Keiko Komi, Hai Pham, Kentaro Akiyama, Masahiro Okada, Toshitaka Oohashi, Takuya Matsumoto, Takuo Kuboki

International Journal of Molecular Sciences 20 ( 5 ) 1097 - 1097 2019年3月

骨組織発生の材料学的再検討が新しい骨組織工学につながる

松本卓也, HARA ES

バイオマテリアル 37 ( 1 ) 50 - 51 2019年

New Functions of Classical Compounds against Orofacial Inflammatory Lesions 査読

Norifumi Moritani, Emilio Hara, Satoshi Kubota

Medicines 5 ( 4 ) 118 - 118 2018年11月

掲載種別：研究論文（学術雑誌）出版者・発行元：MDPI AG

Anti-inflammatory agents have been widely used to ameliorate severe inflammatory symptoms of a number of diseases, and such therapeutics are particularly useful for diseases with intolerable pain without significant mortality. A typical example of this is a disease known as stomatitis; although stomatitis itself is not a life-threatening disease, it severely impairs the individual’s quality of life, and thus a standard therapeutic strategy for it has already been established. The topical application of a bioactive agent is quite easy, and a strong anti-inflammatory agent can be used without significant adverse effects. In contrast, natural products with relatively mild bioactivity are used for systemic intervention. However, new aspects of classical drugs used in these established therapeutic methods have recently been discovered, which is expanding the utility of these compounds to other oral diseases such as osteoarthritis of temporomandibular joints (TMJ-OA). In this review article, after summarizing the general concept and pathobiology of stomatitis, its established therapeutics are explained. Thereafter, recent advances in the research into related compounds, which is uncovering new biological functions of the agents used therein, are introduced. Indeed, regenerative therapeutics for TMJ-OA may be developed with the classical compounds currently being used.

DOI： 10.3390/medicines5040118

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CCN4/WISP1 controls cutaneous wound healing by modulating proliferation, migration and ECM expression in dermal fibroblasts via α5β1 and TNFα 査読

Mitsuaki Ono, Asuka Masaki, Azusa Maeda, Tina M. Kilts, Emilio S. Hara, Taishi Komori, Hai Pham, Takuo Kuboki, Marian F. Young

Matrix Biology 68-69 533 - 546 2018年8月

Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium 査読

Taishi Komori, Mitsuaki Ono, Emilio Satoshi Hara, Junji Ueda, Ha Thi Thu Nguyen, Ha Thi Nguyen, Tomoko Yonezawa, Takahiro Maeba, Aya Kimura-Ono, Takeshi Takarada, Ryusuke Momota, Kenji Maekawa, Takuo Kuboki, Toshitaka Oohashi

Scientific Reports 8 ( 1 ) 2018年2月

Fabrication of Hydroxyapatite Nanofibers with High Aspect Ratio via Low-Temperature Wet Precipitation Methods Under Acidic Conditions: From Molecular and Nano-structural Analyses to Environmental Science 査読

Emilio Hara

Biomineralization 211 - 218 2018年1月

Chondrocyte burst promotes space for mineral expansion 査読

Emilio Satoshi Hara, Masahiro Okada, Noriyuki Nagaoka, Takako Hattori, Letycia Mary Iida, Takuo Kuboki, Takayoshi Nakano, Takuya Matsumoto

Integrative Biology 10 ( 1 ) 57 - 66 2018年1月

差初期石灰化過程を詳細に観察し模倣する

松本卓也, HARA ES

化学工業 69 ( 6 ) 23 - 28 2018年

MCSF orchestrates branching morphogenesis in developing submandibular gland tissue 査読

Gulsan Ara Sathi, Mahmoud Farahat, Emilio Satoshi Hara, Hiroaki Taketa, Hitoshi Nagatsuka, Takuo Kuboki, Takuya Matsumoto

Journal of Cell Science 130 ( 9 ) 1559 - 1569 2017年

Practical whole-tooth restoration utilizing autologous bioengineered tooth germ transplantation in a postnatal canine model 査読

Mitsuaki Ono, Masamitsu Oshima, Miho Ogawa, Wataru Sonoyama, Emilio Satoshi Hara, Yasutaka Oida, Shigehiko Shinkawa, Ryu Nakajima, Atsushi Mine, Satoru Hayano, Satoshi Fukumoto, Shohei Kasugai, Akira Yamaguchi, Takashi Tsuji, Takuo Kuboki

Scientific Reports 7 44522 - 44522 2017年

MSCs feeder layers induce SMG self-organization and branching morphogenesis 査読

Mahmoud Farahat, Gulsan Ara Sathi, Emilio Satoshi Hara, Hiroaki Taketa, Takuo Kuboki, Takuya Matsumoto

PLOS ONE 12 ( 4 ) e0176453 2017年

皮膚創傷治癒過程におけるCCN4/WISP-1の役割

大野充昭, 正木明日香, 前田あずさ, Hara Emilio S., 小盛大志, 久保田聡, Young Marian F., 大橋俊孝, 窪木拓男

日本結合組織学会学術大会プログラム・抄録集 48回 88 - 88 2016年6月

Assessment of CCN2 Independent Modules Regenerative Capacity on Osteoarthritis and Further Selecting the Most Suitable Among them as a Potential Therapeutic Drug 査読

Tarek Abdelkader, Eriko Aoyama, Takashi Nishida, Takako Hattori, Danilo Janune, Emilio S. Hara, Mitsuaki Ono, Yasuhiko Tabata, Takuo Kuboki, Satoshi Kubota, Masaharu Takigawa

FASEB JOURNAL 30 2016年4月

Sleep bruxism frequency and platelet serotonin transporter activities in young adult subjects 査読

Minakuchi, H., Sogawa, C., Miki, H., Hara, E.S., Maekawa, K., Sogawa, N., Kitayama, S., Matsuka, Y., Clark, G.T., Kuboki, T.

Sleep and Breathing 20 ( 1 ) 271 - 276 2016年3月

Sleep bruxism frequency and platelet serotonin transporter activities in young adult subjects 査読

Hajime Minakuchi, Chiharu Sogawa, Haruna Miki, Emilio S. Hara, Kenji Maekawa, Norio Sogawa, Shigeo Kitayama, Yoshizo Matsuka, Glenn Thomas Clark, Takuo Kuboki

SLEEP AND BREATHING 20 ( 1 ) 271 - 276 2016年3月

CCN4/WISP-1 positively regulates chondrogenesis by controlling TGF-beta 3 function 査読

Yoshioka Yuya, Ono Mitsuaki, Maeda Azusa, Kilts Tina M, Hara Emilio Satoshi, Khattab Hany, Ueda Junji, Aoyama Eriko, Oohashi Toshitaka, Takigawa Masaharu, Young Marian F, Kuboki Takuo

Bone 83 162 - 170 2016年

Antagonistic Effects of Insulin and TGF-β3 during Chondrogenic Differentiation of Human BMSCs under a Minimal Amount of Factors 査読

Emilio Satoshi Hara, Mitsuaki Ono, Yuya Yoshioka, Junji Ueda, Yuri Hazehara, Hai Thanh Pham, Takuya Matsumoto, Takuo Kuboki

Cells Tissues Organs 201 ( 2 ) 88 - 96 2016年

Fluocinolone acetonideとTGF-β3を用いた強力な軟骨再生(Potent cartilage regeneration with fluocinolone acetonide and TGF-β3)

Hara Emilio Satoshi, 大野充昭, Pham Hai Thanh, 久保田聡, 滝川正春, Young Marian F., Olsen Bjorn R., 松本卓也, 窪木拓男

日本バイオマテリアル学会大会予稿集 37回 209 - 209 2015年11月

CCN4はTGF-β3の機能を制御することで軟骨細胞分化を正に制御する

吉岡裕也, 大野充昭, 前田あずさ, Hara Emilio Satoshi, Young Marian, 窪木拓男

日本骨代謝学会学術集会プログラム抄録集 33回 216 - 216 2015年7月

糖質コルチコイドの中でfluocinolone acetonideはTGF-β3介在性BMSCの軟骨形成の活性化と関節の軟骨修復を促進において特異的な作用を有する(Among glucocorticoids, fluocinolone acetonide is unique in potentiating TGF-β 3-mediated chondrogenesis of BMSCs and promoting articular cartilage repair)

Hara Emilio Satoshi, 大野充昭, Pham Hai Thanh, Young Marian F., 久保田聡, 滝川正春, 窪木拓男

日本骨代謝学会学術集会プログラム抄録集 33回 161 - 161 2015年7月

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