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論文 - 柳　文修

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MR imaging of epithelial cysts of the oral and maxillofacial region. 国際誌

Miki Hisatomi, Jun-ichi Asaumi, Hironobu Konouchi, Hiroshi Shigehara, Yoshinobu Yanagi, Kanji Kishi

European journal of radiology 48 ( 2 ) 178 - 82 2003年11月

記述言語：英語掲載種別：研究論文（学術雑誌）

The aim of the present study was to review the magnetic resonance (MR) appearance of primary epithelial cysts in order to distinguish the cysts from other possible lesions. MR images were obtained in 27 cases of epithelial cysts, including 7 odontogenic keratocysts, 3 dentigerous cysts, 1 glandular odontogenic cyst, 10 radicular cysts, 4 nasopalatine duct cysts, and 2 nasolabial cysts. In addition, contrast enhanced MR imagings were performed in 12 cases, including 3 odontogenic keratocysts, 1 dentigerous cyst, 1 glandular odontogenic cyst, and 7 radicular cysts. We obtained the following results on the basis of the above MR and contrast enhanced MR findings. (a) Odontogenic keratocysts had a predilection for intermediate-high signal intensity (SI) on T1-weighted images (WI) and heterogeneous low-high SI on T2WI. (b) Dentigerous cysts, glandular odontogenic cyst, radicular cysts and nasolabial cysts showed the same predilection with the SI, which were homogeneous intermediate SI on T1WI and homogeneous high SI on T2WI. (c) The MR images of the nasopalatine duct cysts, which showed homogeneous high SI on T1WI, were specific. (d) The Gd-T1WI would be useful in decisively differentiating odontogenic cysts, which showed rim-enhancement, from tumors consisting of solid components. In conclusion, we were able to obtain more information from the MR and contrast enhanced MR images than from conventional radiograph findings.

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Assessment of pleomorphic adenomas using MRI and dynamic contrast enhanced MRI. 国際誌

Miki Hisatomi, Jun-ichi Asaumi, Yoshinobu Yanagi, Hironobu Konouchi, Hidenobu Matsuzaki, Yasutoshi Honda, Kanji Kishi

Oral oncology 39 ( 6 ) 574 - 9 2003年9月

記述言語：英語掲載種別：研究論文（学術雑誌）

We evaluated magnetic resonance images (MRI) and the value of dynamic contrast enhanced MRI (DCE-MRI) of pleomorphic adenomas retrospectively. MRI was performed for 18 pleomorphic adenomas, including 11 cases with DCE-MRI. We obtained the following results on the MRI and DCE-MRI. (a). Pleomorphic adenomas showed a predilection for homogeneous intermediate signal intensity on T1-weighted images (T1WI), heterogeneous high signal intensity on T2-weighted images, and heterogeneous enhancement on Gd-T1WI. (b). Of 11 contrast index (CI) curves of pleomorphic adenomas, nine CI curves (81.8%) increased gradually to 600 s or increased gradually, reached a plateau, and sustained the plateau to 600 s. The remaining two (18.2%) increased gradually and decreased gradually thereafter. (c). CI curves reached the maximum CI index at 135-300 s.

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Incidentally found and unexpected tumors discovered by MRI examination for temporomandibular joint arthrosis. 国際誌

Yoshinobu Yanagi, Jun-ichi Asaumi, Yuu Maki, Jun Murakami, Miki Hisatomi, Hidenobu Matsuzaki, Hironobu Konouchi, Yosutoshi Honda, Kanji Kishi

European journal of radiology 47 ( 1 ) 6 - 9 2003年7月

記述言語：英語掲載種別：研究論文（学術雑誌）

We examined the frequency of incidentally found or unexpected tumors discovered at the time of magnetic resonance imaging (MRI) examinations in the temporomandibular joint (TMJ) region for patients with suspicion of TMJ arthrosis. Five MR images (T1-weighted transverse scout image and proton density and T2-weighted oblique sagittal images at the open and closed mouth) were acquired. In 2776 MRI examinations of TMJ arthrosis, two tumors were discovered. They consisted of an adenoid cystic carcinoma in the deep portion of the parotid gland, and a malignant tumor extending from the infratemporal fossa to the parapharyngeal space. The rate of incidentally founded or unexpected tumors in TMJ examinations was low (0.072%), but the two tumors found were malignant tumors, and therefore, scout image should be carefully examined, not only used for positing the slice.

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Evaluation of tumor proliferation using dynamic contrast enhanced-MRI of oral cavity and oropharyngeal squamous cell carcinoma. 査読国際誌

Hironobu Konouchi, Jun ichi Asaumi, Yoshinobu Yanagi, Hiroshi Shigehara, Miki Hisatomi, Hidenobu Matsuzaki, Kanji Kishi

Oral oncology 39 ( 3 ) 290 - 5 2003年4月

記述言語：英語掲載種別：研究論文（学術雑誌）

We investigated the relationship between the enhanced patterns acquired by dynamic MRI and the tumor cell proliferation estimated by immunostaining proliferating cell nuclear antigen (PCNA) in oral squamous cell carcinoma (SCC). Thirty patients with primary oral SCC underwent dynamic contrast enhanced (DCE)-MRI using a three-dimensional fast imaging with steady-state precession sequence. Tumor cell proliferation of all surgical specimens was evaluated using immunohistochemical staining with the anti-PCNA antibody. The relationship between the dynamic MRI parameters (maximum CI and maximum CI gain) and the PCNA labeling index was statistically analyzed using regression analysis. The time contrast index curves of all cases showed a rapid and high uptake pattern. The PCNA labeling index showed a significant correlation with maximum CI and maximum CI gain (P<0.0001, r=0.866 and P=0.0019, r=0.544, respectively). The assessment of DCE-MRI parameters may provide valuable information for tumor cell proliferation of the patients with oral cancer.

DOI： 10.1016/S1368-8375(02)00119-7

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Adenomatoid odontogenic tumor: correlation of MRI with histopathological findings. 国際誌

Hironobu Konouchi, Jun-ichi Asaumi, Yoshinobu Yanagi, Miki Hisatomi, Kanji Kishi

European journal of radiology 44 ( 1 ) 19 - 23 2002年10月

記述言語：英語掲載種別：研究論文（学術雑誌）

Adenomatoid odontogenic tumor is a rare benign and odontogenic tumor that is frequently misdiagnosed as other odontogenic cysts and tumors on radiographic examination. To acquire additional information of adenomatoid odontogenic tumor, we performed magnetic resonance imagings (MRI) at a case of adenomatoid odontogenic tumor. The lesion was divided between the peripheral portion with a thick circular shape and the central portion with a round shape on the basis of the signal intensity (SI) of MRI. The peripheral portion showed intermediate SI contained multifocal no SI on T1WI, high SI contained multifocal no SI on T2WI, and heterogeneous enhancement on CE-T1WI. These multifocal areas corresponded to the numerous punctate radiopaque foci shown on computed tomography. The central portion showed homogeneous low SI on T1WI, homogeneous very high SI on T2WI, and no enhancement on CE-T1WI. Macroscopic examination revealed the round shaped lesion included one large cystic space correspondent to the central portion with a clear cystic wall correspondent to the peripheral portion on MRI. The MRI features corresponded to the macroscopic findings of the histopathological examination.

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Mandibular metastasis presenting as the initial maifestation of malignant pheochromocytoma. 国際誌

Yoshinobu Yanagi, Jun-ichi Asaumi, Miki Hisatomi, Hironobu Konouchi, Toru Wakasa, Kanji Kishi

European journal of radiology 44 ( 1 ) 5 - 9 2002年10月

記述言語：英語掲載種別：研究論文（学術雑誌）

A case of 59-year-old male patient presenting with metastasis to the mandible from malignant pheochromocytoma is described. The conventional radiographs and CT images suggested that the lesion was malignant osteogenic tumors or metastatic tumors due to the existence of calcification and widespread periosteal sunburst spiculation. On MRI, an expansive mass was clearly depicted and the signal intensities of the lesion were low to intermediate on T1 weighted image with intermediate to high signal intensity on T2 weighted image. A strong enhancement of the lesion was also observed on contrast enhanced T1 weighted image. On maximum intensity projection image in the arterial phase, the mass showed exceedingly early enhancement and excessively dislocated adjacent vessels. The diagnosis of a pheochromcytoma was difficult on the basis of these imagings. The final diagnosis was based on a biopsy of the mandible and I-131 Meta-iodobenzylguanidine scintigraphy (MIBG) scintigraphy. A primary lesion of the right adrenal showed low uptake due to wide centric necrosis and metastatic lesions of liver, lumber vertebrae, ribs and sacroiliac joint showed high uptake on the I-131 MIBG scintigraphy. The final diagnosis was nonfunctioning malignant pheochromocytoma due to the absence of elevation of catecholamine or its metabolite.

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Assessment of dynamic MRI of Warthin's tumors arising as multiple lesions in the parotid glands. 査読国際誌

Miki Hisatomi, Jun-ichi Asaumi, Hironobu Konouchi, Yoshinobu Yanagi, Hidenobu Matsuzaki, Kanji Kishi

Oral oncology 38 ( 4 ) 369 - 72 2002年6月

記述言語：英語掲載種別：研究論文（学術雑誌）

We examined three patients with multiple synchronous Warthin's tumors in the bilateral parotid and described the value of using dynamic MRI. The time course of the contrast index (CI curves) was calculated from a dynamic series. Warthin's tumors showed intermediate signal intensity on T1WI, heterogeneous high and intermediate signal intensity on T2WI and a slight enhancement on Gd-T1WI. Warthin's tumors of CI curves showed specific findings. CI curves in each lesion showed the same pattern. It was difficult to diagnose masses as Warthin's tumors using only MR images on T1, T2 and Gd-T1WI. Dynamic MRI can distinguish Warthin's tumors from other possible tumors except for oncocytoma. Therefore, the use of dynamic MRI is recommended as a diagnostic method for Warthin's tumors in multiple synchronous lesions of the parotid gland.

DOI： 10.1016/S1368-8375(01)00073-2

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僧帽筋MRI-T2強調画像のCold Pressor刺激時信号強度変化

水口真実, 前川賢治, 柳文修, 井上栄徳, 鈴木康司, 窪木拓男, 矢谷博文, 岸幹二, Clark Glenn T.

日本補綴歯科学会雑誌 45 ( 106回特別 ) 182 - 182 2001年10月

Solitary Bone Cyst のMRI評価

松崎秀信, 本多康聡, 河井紀子, 久富美紀, 樋口譲, 柳文修, 岸幹二

歯科放射線 41 37 - 37 2001年9月

口腔癌における dynamic MRI を用いたリンパ節転移の評価

此内浩信, 繁原宏, 若狭亨, 河井紀子, 村上純, 柳文修, 岸幹二

歯科放射線 41 35 - 35 2001年9月

Correlation of the near-infrared spectroscopy signals with signal intensity in T<inf>2</inf>-weighted magnetic resonance imaging of the human masseter muscle 査読国際誌

Takuo Kuboki, Koji Suzuki, Kenji Maekawa, Mami Inoue-Minakuchi, Claver O. Acero, Yoshinobu Yanagi, Toru Wakasa, Kanji Kishi, Hirofumi Yatani, Glenn T. Clark

Archives of Oral Biology 46 ( 8 ) 721 - 727 2001年7月

記述言語：英語掲載種別：研究論文（学術雑誌）

The purpose of this study was to compare and contrast blood volume changes transcutaneously measured using near-infrared (NIR) spectroscopy against water signal intensity changes taken from a transverse T2-weighted MR image of the masseter muscle in healthy human subjects before, during and after contraction. Eight healthy non-smoking males with no history of chronic muscle pain or vascular headaches participated (mean age: 23.9 ± 0.6 years). The MRI data were gathered using a turbo spin echo sequence (TR: 2300 ms; TE: 90 ms; FOV: 188 × 300 mm; scanning time: 30 s; slice thickness: 10 mm) and the slice level was set at the mid-point between the origin and insertion of the masseter. Intramuscular haemoglobin (Hb) levels and water content of the right masseter muscle were continuously monitored for 2 min before, 30 s during and 15 min after a maximum voluntary clenching (MVC) task. Both the near-infrared and MRI data were baseline-corrected and normalized and mean levels were established and plotted. Plots of the data showed that both near-infrared-based total Hb and T2-weighted MRI-based signal-intensity levels clearly decreased during contraction and a clear post-contraction rebound response was evident after the contraction. The near-infrared data were found to be highly correlated with MRI-based signal-intensity data (Pearson's r = 0.909, P < 0.0001). In conclusion, these data provide powerful evidence that near-infrared data (total Hb), transcutaneously taken from the masseter muscle in humans, will reflect the intramuscular water signal intensity changes seen using a T2-weighted MRI imaging method. © 2001 Elsevier Science Ltd.

DOI： 10.1016/S0003-9969(01)00030-9

浅海淳一, 久富美紀, 此内浩信, 柳文修, 繁原宏, 岸幹二

歯科放射線 40 ( 増刊 ) 51 - 51 2000年10月

エナメル上皮腫における造影MRIの有用性

久富美紀, 此内浩信, 浅海淳一, 柳文修, 繁原宏, 岸幹二

歯科放射線 39 ( 増刊 ) 34 - 34 1999年10月

口腔癌の頸部リンパ節転移のCT像の検討

藤木知一, 若狭亨, 柳文修

歯科放射線 38 ( 1 ) 3 - 9 1998年3月

記述言語：日本語出版者・発行元：(NPO)日本歯科放射線学会

口腔扁平上皮癌患者89例の132リンパ節群について検討した.転移リンパ節は53群であった.各診断基準項目でみたリンパ節転移は,短径が1cm以上のリンパ節群74群で58.1%,1cm未満の58群で17.2%,円形を示す75群で38.7%,リングエンハンスメントを示す27群で70.4%,複数のリンパ節の集簇のみられる4群で75%,リンパ節周囲の脂肪層の消失があるもの1例で100%であった.またこれらの複合所見では,短径1cm以上で円形のものでは22/37,短径1cmでリングエンハンスメントを示すものでは18/23,円形でリングエンハンスメントを示すものでは9/15,更に短径が1cm以上で円形になりしかもリングエンハンスメントを示すものでは9/14であった

DOI： 10.11242/dentalradiology1960.38.3

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その他リンク： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=1998&ichushi_jid=J00567&link_issn=&doc_id=19980414190001&doc_link_id=%2Fcg7dentr%2F1998%2F003801%2F002%2F0003-0009%26dl%3D0&url=http%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fcg7dentr%2F1998%2F003801%2F002%2F0003-0009%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

顎顔面領域MRAにおける血管描出能に関する研究(第2報)

柳文修

歯科放射線 37 ( 増刊 ) 86 - 86 1997年9月

顎口腔領域に発現した転移性悪性腫瘍ならびに原発性悪性腫瘍の遠隔転移例の検討

清水健一郎, 羽澤和雅, 柳文修, 長谷川勳, 若狭亨, 岸幹二

歯科放射線 36 61 - 61 1996年9月

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