Updated on 2025/06/07

写真a

 
Hirotaka Ueda
 
Organization
Faculty of Medicine, Dentistry and Pharmaceutical Sciences Assistant Professor
Position
Assistant Professor
External link

Degree

  • 博士(歯学) ( 岡山大学 )

Research Interests

  • Cleft lip and palate

  • Orthodontics

  • Neurophysiology

Research Areas

  • Life Science / Developmental dentistry  / Orthodontics

  • Life Science / Neuroscience-general  / Neurophysiology

Education

  • Okayama University   Graduate School of Medicine, Dentistry and Pharmaceutical Sciences (Doctor's Course)   Department of Orthodontics, Science of Functional Recovery and Reconstruction

    2005.4 - 2009.3

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    Country: Japan

  • Okayama University   Dental school   Dentistry course

    1999.4 - 2005.3

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    Country: Japan

Research History

  • Okayama University   Graduate School of Medicine , Dentistry and Pharmaceutical Sciences   Assistant Professor

    2017.7

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    Country:Japan

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  • Kagoshima University   Graduate School of Medical and Dental Sciences   Assistant Professor

    2014.4 - 2017.6

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  • Kagoshima University Hospital   Department of Orthodontics   Assistant Professor

    2010.4 - 2014.3

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  • Okayama University Hospital   Department of Orthodontics   Medical staff (orthodontist)

    2009.4 - 2010.3

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  • Okayama University   Graduate School of Medicine , Dentistry and Pharmaceutical Sciences

    2005.4 - 2009.3

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    Country:Japan

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  • Okayama University   Dental School

    1999.4 - 2005.3

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    Country:Japan

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Professional Memberships

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Papers

  • Long~term follow-up of a surgical orthodontic case with mandibular protrusion and metal allergy Reviewed

    Sawako YAGABI, Aya MAEDA-IINO, Hirotaka UEDA, KOtaro TAKAHASHI, Shouichi MIYAWAKI

    The Journal of Kyushu Orthodontic Society   20 ( 1 )   13 - 19   2024.12

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  • A case of crowding with gingival recession treated by space making by molars' distal movement and connective tissue graft Reviewed

    Hashimoto Mana, Ueda Hirotaka, Okubo Kaori, Kamioka Hiroshi

    The Journal of Chu-shikoku Orthodontic Society   36 ( 1 )   47 - 56   2024.8

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  • A comparative study of post operative morphological changes of hard and soft tissue following MASDO and mandibular osteotomy in patients with cleft lip and palate Reviewed

    YASUTOMI Narumi, UEDA Hirotaka, ARIMURA Yuki, MORITANI Norifumi, MATSUMURA Tatsushi, KAMIOKA Hiroshi, IIDA Seiji

    The Journal of Chu-shikoku Orthodontic Society   35 ( 1 )   37 - 50   2023.8

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  • Improvement of anterior disc displacement on the mandibular deviated side after intraoral vertical ramus osteotomy in a patient with facial asymmetry: a case report Reviewed International journal

    Hirotaka Ueda, Naoki Oka, Tsuyoshi Shimo, Akira Sasaki, Takashi Yamashiro, Hiroshi Kamioka

    Clinical and Investigative Orthodontics   81 ( 1 )   58 - 67   2022.3

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  • 下顎枝垂直骨切り術後に顎関節症状の改善と偏位側への側方滑走運動の改善を認めた顔面非対称症例 Reviewed

    植田 紘貴, 岡 直毅, 上岡 寛

    中・四国矯正歯科学会雑誌 32巻 1号 (頁 51 ~ 64)   32 ( 1 )   51 - 64   2020.8

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    Authorship:Lead author   Language:Japanese   Publisher:中・四国矯正歯科学会  

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  • A case with anterior open bite, tongue thrusting and mandibular deviation orthodontically treated by using miniscrews for intrusion and distalization of mandibular molars Reviewed

    Mayu Suga, Hirotaka Ueda, Sayuri Yamanishi, Shouich Miyawaki

    Journal of The Kyushu Orthodontic Society   14 ( 1 )   25 - 31   2019.3

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  • Effects of cevimeline on excitability of parasympathetic preganglionic neurons in the superior salivatory nucleus of rats Reviewed International journal

    Yoshihiro Mitoh, Hirotaka Ueda, Hiroyuki Ichikawa, Masako Fujita, Motoi Kobashi, Ryuji Matsuo

    AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL   206   1 - 7   2017.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.autneu.2017.05.010

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  • Vagal afferent activation induces salivation and swallowing-like events in anesthetized rats. Reviewed International journal

    Hirotaka Ueda, Mayu Suga, Takakazu Yagi, Ikue Kusumoto-Yoshida, Hideki Kashiwadani, Tomoyuki Kuwaki, Shouichi Miyawaki

    American journal of physiology. Regulatory, integrative and comparative physiology   311 ( 5 )   R964-R970 - R970   2016.11

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1152/ajpregu.00292.2016

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  • A Class II patient with bimaxillary protrusion and mandibular inclined third molars treated with orthodontic anchoring screws: A case report Reviewed

    Mayu Suga, Hirotaka Ueda, Fumiaki Kitashima, Shouich Miyawaki

    Orthodontic Waves   74 ( 4 )   112 - 119   2015.12

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Elsevier Ltd  

    DOI: 10.1016/j.odw.2015.04.001

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  • The roles of salivary secretion, brain-gut peptides, and oral hygiene in obesity Reviewed International journal

    Hirotaka Ueda, Takakazu Yagi, Haruka Amitani, Akihiro Asakawa, Satoshi Ikeda, Shouichi Miyawaki, Akio Inui

    OBESITY RESEARCH & CLINICAL PRACTICE   7 ( 5 )   E321 - E329   2013.9

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    DOI: 10.1016/j.orcp.2013.05.001

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  • The role of ghrelin in patients with functional dyspepsia and its potential clinical relevance (Review). Reviewed International journal

    Takakazu Yagi, Akihiro Asakawa, Hirotaka Ueda, Shouichi Miyawaki, Akio Inui

    International journal of molecular medicine   32 ( 3 )   523 - 31   2013.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3892/ijmm.2013.1418

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  • The role of zinc in the treatment of taste disorders. Reviewed International journal

    Takakazu Yagi, Akihiro Asakawa, Hirotaka Ueda, Satoshi Ikeda, Shouichi Miyawaki, Akio Inui

    Recent patents on food, nutrition & agriculture   5 ( 1 )   44 - 51   2013.4

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    DOI: 10.2174/2212798411305010007

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  • The role of ghrelin, salivary secretions, and dental care in eating disorders. Reviewed International journal

    Takakazu Yagi, Hirotaka Ueda, Haruka Amitani, Akihiro Asakawa, Shouichi Miyawaki, Akio Inui

    Nutrients   4 ( 8 )   967 - 89   2012.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/nu4080967

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  • Regulative roles of ghrelin in ingestive behavior, upper gastrointestinal motility, and secretion Reviewed

    Hirotaka Ueda, Takakazu Yagi, Haruka Amitani, Akihiro Asakawa, Shouichi Miyawaki, Akio Inui

    Current Nutrition and Food Science   8 ( 3 )   188 - 195   2012

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2174/157340112802651112

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  • Muscarinic receptor immunoreactivity in the superior salivatory nucleus neurons innervating the salivary glands of the rat Reviewed International journal

    Hirotaka Ueda, Yoshihiro Mitoh, Masako Fujita, Motoi Kobashi, Takashi Yamashiro, Tomosada Sugimoto, Hiroyuki Ichikawa, Ryuji Matsuo

    NEUROSCIENCE LETTERS   499 ( 1 )   42 - 46   2011.7

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.neulet.2011.05.029

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  • Cevimeline enhances the excitability of rat superior salivatory neurons Reviewed

    Hirotaka Ueda, Yoshihiro Mitoh, Hiroyuki Ichikawa, Motoi Kobashi, Takashi Yamashiro, Ryuji Matsuo

    Journal of Medical Investigation   56 ( 1 )   267 - 269   2009

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    DOI: 10.2152/jmi.56.267

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  • 下顎歯列弓幅径が過大な骨格性下顎前突症に対し上顎正中三分割術により上顎骨の拡大を施行した一例

    穴田 理嵯, 早野 暁, 西山 明慶, 植田 紘貴, 伊原木 聰一郎, 上岡 寛

    日本矯正歯科学会大会プログラム・抄録集   83回   259 - 259   2024.10

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  • 光学印象で前方骨片の可動性に配慮し無圧印象することで上顎骨前方部骨延長(MASDO)術後の安定を図った一例 Reviewed

    竹本 史子, 植田 紘貴, 中西 泰之, 西谷 悠希, 兵藤 藍子, 有村 友紀, 飯田 征二, 上岡 寛

    日本口蓋裂学会雑誌   49 ( 2 )   153 - 153   2024.4

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  • 扇型の上顎骨拡大により正常被蓋を獲得した片側性唇顎口蓋裂の3症例 Reviewed

    西谷 悠希, 有村 友紀, 天野 克比古, 兵藤 藍子, 植田 紘貴, 河野 加奈, 大久保 香織, 竹本 史子, 上岡 寛, 飯田 征二

    日本口蓋裂学会雑誌   49 ( 2 )   161 - 161   2024.4

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  • 重度開口障害により口蓋裂未手術のロバン・シークエンス症例で栓塞子を併用して矯正歯科治療を行った一例 Reviewed

    穴田 理嵯, 植田 紘貴, 古西 隆之, 中川 敦子, 有村 友紀, 飯田 征二, 上岡 寛

    日本口蓋裂学会雑誌   49 ( 2 )   154 - 154   2024.4

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  • 複合的な要因を有する骨格性下顎骨後退症例に対して下顎骨前方移動術を施行し機能的改善を認めた一治験例 Reviewed

    中西 泰之, 植田 紘貴, 吉岡 徳枝, 伊原木 聰一郎, 上岡 寛

    日本顎変形症学会雑誌   33 ( 2 )   187 - 187   2023.5

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  • . Reviewed

    Harumi Ota, Mitsuhiro Hoshijima, Yasuyuki Nakanishi, Hirotaka Ueda, Satoru Hayano, Hiroshi Kamioka

    The Journal of Okayama Dental Society   40 ( 2 )   19 - 24   2021.12

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  • 岡山大学大学院歯科矯正学分野研究室における過去15年間および2013年から2016年の4年間の岡山大学の学生および職員に対する矯正相談の実態調査 Reviewed

    田中智代, 村上隆, 片岡伴記, 石原嘉人, 植田紘貴, 早野暁, 星島光博, 中村政裕, 川邉紀章, 上岡寛

    岡山歯学会雑誌   36 ( 2 )   45 - 51   2018

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  • 歯科矯正用アンカースクリューを併用して非抜歯治療を行った骨格性II級ハイアングル症例の一治験例 Reviewed

    植田紘貴, 迫口陽子, 宮脇正一

    九州矯正歯科学会雑誌   11 ( 1 )   10‐16 - 16   2016

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  • Psychological State and Concerns of Guardians of Patients with Cleft Lips and Alveoli with/without Cleft Palates while Undergoing Orthodontic Treatment Reviewed

    福重雅美, 前田綾, 上原沢子, 植田紘貴, 帆北友紀, 中村典史, 宮脇正一

    日本口蓋裂学会雑誌   40 ( 1 )   13 - 22   2015.4

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    DOI: 10.11224/cleftpalate.40.13

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  • 従来の固定式大臼歯遠心移動装置とスケレタルアンカレッジ装置の臼歯部と前歯部への治療効果に関する系統的レビュー Reviewed

    八木孝和, 菅真有, 植田紘貴, 友成博, 大牟禮治人, 宮脇正一

    九州矯正歯科学会雑誌   9 ( 1 )   1 - 16   2013

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  • ミニスクリューを用いて重度の前歯部開咬を改善した症例 Reviewed

    冨田奈緒, 上岡寛, 植田紘貴, 加野小奈美, 山城隆

    中・四矯正歯誌   24 ( 1 )   63 - 71   2012

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  • 岡山大学病院矯正歯科における来院患者の実態調査 Reviewed

    白賀のり子, 上岡寛, 片岡伴記, 植田紘貴, 安藤涼子, 石原嘉人, 柳田剛志, 村上隆, 黒坂寛, 菅原康代, 本城正, 川邉紀章, 山城隆

    岡山歯学会雑誌   28 ( 2 )   107 - 114   2009.12

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  • ラット上唾液核ニューロンにおけるセビメリンの興奮性作用に関する電気生理学的解析 Reviewed

    植田 紘貴

    岡山歯学会雑誌   28 ( 1 )   1 - 16   2009.6

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    Authorship:Lead author   Language:Japanese   Publishing type:Doctoral thesis   Publisher:岡山歯学会  

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  • 植田紘貴、上岡 寛、川邉紀章、山城 隆, 外傷性咬合ならびに歯周疾患を伴う成人下顎前突症例 Reviewed

    植田紘貴, 上岡 寛, 川邉紀章, 山城 隆

    中・四矯正歯誌   21   47 - 53   2009

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  • Hormonal, pH, and calcium regulation of Connexin 43-mediated dye transfer in osteocytes in chick calvaria Reviewed International journal

    Yoshihito Ishihara, Hiroshi Kamioka, Tadashi Honjo, Hirotaka Ueda, Teruko Takano-Yamamoto, Takashi Yamashiro

    JOURNAL OF BONE AND MINERAL RESEARCH   23 ( 3 )   350 - 360   2008.3

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    DOI: 10.1359/JBMR.071102

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MISC

  • The effect of KATP channel modulators on taste sensitivity in mice Reviewed

    Chika Sawai, Kengo Horie, Yoshihiro Mitoh, Hirotaka Ueda, Hiroshi Kamioka

    APPW2025   2025.3

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  • Digital optical impressions to fabricate safe and accurate devices for patient with CLCP: practical cases in Okayama University Hospital Reviewed

    Hirotaka UEDA

    CLEFT TOKYO 2024   2024.7

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  • Intraoral and Perinasal Digital Impression to create PNAM in a Neonate with Unilateral Cleft Lip and Palate Reviewed

    Hirotaka Ueda, Shigetomo Tsuji, Masahiro Nakamura, Hiroshi Kamioka

    14th International Cleft Congress (CLEFT 2022)   2022.7

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  • A case of mandibular prognathism carrying deep curve of Spee treated by two-stage osteotomies of Kole and Le Fort I/ genioplasty Reviewed

    Kazuki Nakatsuji, Katsuhiko Amano, Saori Tanizaki, Yuki Arimura, Sho Akashi, Yuki Nagata, Hirotaka Ueda, Hiroshi Kamioka, Seiji Iida

    The Japanese Journal of Jaw Deformities   35 ( 2 )   149 - 149   2025.5

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  • A TMD Ⅲb case with retrognathia, open-bite treated with segmental Le Fort I and BSSO Reviewed

    Fumiko Takemoto, Hirotaka Ueda, Miku Yasumitsu, Akiyoshi Nishiyama, Soichiro Ibaragi, Hiroshi Kamioka

    The Japanese Journal of Jaw Deformities   35 ( 2 )   139 - 139   2025.5

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  • Clinical findings of Moebius syndrome Reviewed

    Yuji Komiyama, Hirotaka Ueda, Hiroshi Kaioka

    2024.7

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  • A clinical application of optical impression for replacing a PLP with an expanding plate with bulb Reviewed

    Gohji Kozaki, HirotakaUeda, Yuki Arimura, Seiji Iida, Hiroshi Kamioka

    2024.7

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  • エポキシ樹脂製の作業模型でろう着を伴う矯正装置は作製可能か? Reviewed

    植田紘貴

    第67回中・四国矯正歯科学会大会・抄録集   2024.7

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  • An asymmetry and prognathism with ristricted jaw movement treated by Le Fort I and IVRO Reviewed

    Fumiko Takemoto, Hirotaka Ueda, Akiyoshi Nishiyama, Soichiro Ibaragi, Hiroshi Kamioka

    34 ( 2 )   177 - 177   2024.6

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  • A case of cleft palate treated by maxillary distraction osteogenesis with evaluation of velopharyngeal function Reviewed

    Hirotaka Ueda, Naoki Oka, Yasuyuki Nakanishi, Yuki Arimura, Seiji lida, Hiroshi Kamioka

    34 ( 2 )   137 - 137   2024.6

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  • Distraction osteogenesis for underdeveloped maxilla in patient with cleft lip and palate Reviewed

    Yuki Arimura, Katsuhiko Amano, Kazuki Nakatsuji, Yuki Nagata, Soma Kato, Hirotaka Ueda, Hiroshi Kamioka, Seiji lida

    34 ( 2 )   136 - 136   2024.6

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  • Effects of cervical vagal nerve stimulation on respiration and blood pressure variability and tissue blood flow in salivary gland Reviewed

    Hirotaka Ueda, Yoshihiro Mitoh, Hiroshi Kamioka, Ryusuke Yoshida

    183 - 183   2024.3

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  • メビウス症候群の口腔・顎顔面形態の臨床所見について Reviewed

    小見山裕司, 植田紘貴, 上岡寛

    第4回せとうち臨床遺伝研究会抄録集   19 - 19   2024.3

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  • A case of connective tissue graft for a moderate crowding with gingival recession Reviewed

    HASHIMOTO M, UEDA H, OKUBO K, KAMIOKA H

    261 - 261   2023.11

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  • Trial of PLP for patients with submucosal cleft palate using an oral scanner Reviewed

    KOZAKI G, UEDA H, KAMIOKA H

    265 - 265   2023.11

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  • 合指による自力清掃困難なアペール症候群患者に対して口腔衛生習慣の確立を目指した1症例 Reviewed

    西山由夏, 植田紘貴, 高橋麻里子, 小倉早妃, 三浦留美, 谷崎沙織, 上岡寛

    日本歯科衛生学会 第18回学術大会 抄録集   2023.9

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  • . Reviewed

    Yuri Yoshikawa, Hirotaka Ueda, Yuki Arimura, Seiji Iida, Hiroshi Kamioka

    2023.7

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  • 顎関節症状を伴う顔面非対称症例に対して Le FortI型骨切り術とIVSRO を施行した一治験例 Reviewed

    田中敦子, 植田紘貴, 石田朋子, 中辻和樹, 森谷徳文, 飯田征二, 上岡寛

    第33回日本顎変形症学会総会・学術大会プログラム・抄録号   33 ( 2 )   208 - 208   2023.5

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  • 岡山大学病院口唇裂・口蓋裂総合治療センターにおける受診患者の臨床統計的調査 Reviewed

    吉川友理, 植田紘貴, 中西泰之, 有村友紀, 妹尾貴矢, 木股敬裕, 飯田征二, 上岡寛

    日本口蓋裂学会雑誌抄録号   48 ( 2 )   194 - 194   2023.5

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  • 上顎骨の著しい狭窄と交叉咬合を伴う両側性唇顎口蓋裂症例に骨延長術を施行した一治験例 Reviewed

    竹本史子, 植田紘貴, 中西泰之, 岡直毅, 岩本悠希, 三上彩可, 兵藤藍子, 有村友紀, 飯田征二, 上岡寛

    日本口蓋裂学会雑誌抄録号   48 ( 2 )   184 - 184   2023.5

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  • 早期開口訓練により下顎枝垂直骨切り術後のcondylar sagの改善を図った骨格性下顎前突症の一治験例 Reviewed

    石田朋子, 植田紘貴, 有村友紀, 森谷徳文, 飯田征二, 上岡寛

    第33回日本顎変形症学会総会・学術大会プログラム・抄録号   33 ( 2 )   2023.5

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  • 複合的な要因を有する骨格性下顎骨後退症例に対して下顎骨前方移動術を施行し機能的改善を認めたー治験例 Reviewed

    中西泰之, 植田紘貴, 吉岡徳枝, 伊原木 聰一郎, 上岡寛

    第33回日本顎変形症学会総会・学術大会プログラム・抄録号   33 ( 2 )   2023.5

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  • 外科的矯正治療を行なった症候群性頭蓋縫合早期癒合症患者の長期経過を追った3症例 Reviewed

    河野 加奈, 村上 隆, 植田 紘貴, 片岡 伴記, 川邉 紀章, 原 規子, 大住 隆太, 上岡 寛

    日本矯正歯科学会大会プログラム・抄録集   81回   232 - 232   2022.10

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  • 上顎骨のカントを伴う下顎骨偏位症例において非外科的に咬合を確立し良好な長期的予後を得た一治験例 Reviewed

    中逵 敬太, 植田 紘貴, 村上 隆, 上岡 寛

    日本矯正歯科学会大会プログラム・抄録集   81回   217 - 217   2022.10

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  • NSAIDs系鎮痛薬の常用による歯の移動の遅延を認めた上下顎前突症例の一治験例 Reviewed

    中西 泰之, 植田 紘貴, 星島 光博, 井澤 俊, 上岡 寛

    日本矯正歯科学会大会プログラム・抄録集   81回   229 - 229   2022.10

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  • . Reviewed

    Mitsuhiro Hoshijima, Harumi Ota, Yasuyuki Nakanishi, Hirotaka Ueda, Satoru Hayano, Hiroshi Kamioka

    2022.4

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  • Perinasal and intraoral digital impression to provide PNAM appliance Reviewed

    辻重智, 植田紘貴, 中村政裕, 中村政裕, 上岡寛, 上岡寛

    日本口蓋裂学会雑誌   47 ( 2 )   2022

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  • Surgical orthodontic approach for the case of BCLP with severe damaged incisal bone using DO Reviewed

    兵藤藍子, 有村友紀, 植村亜由美, 薬師寺翔太, 安富成美, 三上彩可, 大久保(田畑)香織, 植田紘貴, 上岡寛, 飯田征二

    日本口蓋裂学会雑誌   47 ( 2 )   162 - 162   2022

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  • A case of cleft palate treated by maxillary distraction osteogenesis with evaluation using nasometer Reviewed

    岡直毅, 植田紘貴, 中逵敬太, 中西泰之, 三上彩可, 兵藤藍子, 安富成美, 薬師寺翔太, 有村友紀, 古西隆之, 飯田征二, 上岡寛

    日本口蓋裂学会雑誌   47 ( 2 )   127 - 127   2022

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  • A case of UCLP on the left side with midline deviation, a congenital missing tooth on the right side Reviewed

    太田明美, 植田紘貴, 中西泰之, 安富成美, 有村友紀, 飯田征二, 上岡寛

    日本口蓋裂学会雑誌   47 ( 2 )   149 - 149   2022

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  • A case of long-term prognosis of skeletal mandibular protrusion involving condylar angle rotation after IVRO Reviewed

    穴田理嵯, 植田紘貴, 森谷徳文, 松村達志, 飯田征二, 上岡寛

    日本顎変形症学会雑誌   32 ( 2 )   173 - 173   2022

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  • A case of orthognathic surgery for skeletal mandibular retrognathia with temporomandibular joint disorder Reviewed

    岡直毅, 植田紘貴, 森谷徳文, 松村達志, 飯田征二, 上岡寛

    日本顎変形症学会雑誌   32 ( 2 )   172 - 172   2022

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  • Comparison of hard-soft tissue changes after MASDO and mandibular osteotomy in patients with CLP Reviewed

    安富成美, 有村友紀, 薬師寺翔太, 植田紘貴, 上岡寛, 飯田征二

    日本口蓋裂学会雑誌   47 ( 2 )   160 - 160   2022

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  • Long term stability after re-bone graft during adult period in a patient with UCLP on the left side Reviewed

    植田紘貴, 植田紘貴, 谷崎沙織, 岡直毅, 飯田征二, 飯田征二, 木股敬裕, 木股敬裕, 山城隆, 上岡寛, 上岡寛

    日本口蓋裂学会雑誌   46 ( 2 )   118 - 118   2021

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  • Patient distribution managed by Orthodontics in Okayama University Hospital Advanced CLCP Center Reviewed

    植田紘貴, 植田紘貴, 岡直毅, 中村政裕, 中村政裕, 有村友紀, 有村友紀, 徳山英二郎, 徳山英二郎, 妹尾貴矢, 妹尾貴矢, 松村達志, 松村達志, 木股敬裕, 木股敬裕, 飯田征二, 飯田征二, 上岡寛, 上岡寛

    日本口蓋裂学会雑誌   46 ( 2 )   136 - 136   2021

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  • A case of growing patient with occlusal cant and facial asymmetry associated with ocular torticollis Reviewed

    植田紘貴, 難波裕生, 山城隆, 上岡寛

    日本顎変形症学会雑誌   31 ( 2 )   134 - 134   2021

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  • A functional cross-bite with restricted maxillary arch and midline deviation improved by rapid maxillary expansion Reviewed

    植田紘貴, 難波裕生, 岡直毅, 山城隆, 上岡寛

    日本矯正歯科学会大会プログラム・抄録集   80th   226 - 226   2021

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  • Clinical attempt to wear Hotz appliance at first consultation day Reviewed

    植田紘貴, 植田紘貴, 国富陽介, 中西泰之, 村上隆, 徳山英二郎, 徳山英二郎, 上岡寛, 上岡寛

    日本口蓋裂学会雑誌   45 ( 2 )   147 - 147   2020.5

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  • Clinical investigation of patients with cleft lip and palate treated by Maxillary Anterior Segmental Distraction Osteogenesis (MASDO) Reviewed

    岡本成美, 岡本成美, 松村達志, 藤田佑貴, 有村友紀, 有村友紀, 薬師寺翔太, 植田紘貴, 植田紘貴, 上岡寛, 上岡寛, 飯田征二, 飯田征二, 飯田征二

    日本口蓋裂学会雑誌   45 ( 2 )   164 - 164   2020.5

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  • A mandibular prognathism with resolved TMJ clicking and increased anterior, lateral condyle movement after IVRO Reviewed

    植田紘貴, 岡直毅, 森谷徳文, 松村達志, 飯田征二, 上岡寛

    日本顎変形症学会雑誌   30 ( 2 )   159 - 159   2020

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  • 頭蓋骨形成術、Le Fort III型骨切り術、Le Fort I型骨切り術を含む治療を行ったApert症候群の一例 Reviewed

    大住 隆太, 川邉 紀章, 植田 紘貴, 片岡 伴記, 本城 正, 上岡 寛

    中・四国矯正歯科学会雑誌   31 ( 1 )   60 - 60   2019.8

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  • スプリントによる下顎位確認後に下顎枝垂直骨切り術を行い偏位側への側方滑走運動が改善した顔面非対称症例 Reviewed

    植田 紘貴, 岡 直毅, 上岡 寛

    日本顎変形症学会雑誌   29 ( 2 )   192 - 192   2019.5

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  • 岡山大学病院口唇裂・口蓋裂総合治療センター開設後の受診患者の実態調査 Reviewed

    植田 紘貴, 国富 陽介, 中西 泰之, 片岡 伴記, 村上 隆, 木股 敬裕, 飯田 征二, 上岡 寛

    日本口蓋裂学会雑誌   44 ( 2 )   147 - 147   2019.4

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  • 下顎枝垂直骨切り術後に偏位側顎関節の非復位性関節円板前方転位の改善を認めた顔面非対称症例の一治験例 Reviewed

    植田紘貴, 国富陽介, 岡直毅, 村上隆, 佐々木朗, 山城隆, 上岡寛

    日本矯正歯科学会大会プログラム・抄録集   78th   251 - 251   2019

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  • 重度の歯のフッ素症に対し歯面処理効果を確認した上顎前突症例 Reviewed

    田畑 香織, 植田 紘貴, 石本 和也, 村上 隆, 上岡 寛

    日本矯正歯科学会大会プログラム・抄録集   77回   324 - 324   2018.10

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  • 過去3年間における岡山大学病院口唇裂・口蓋裂総合治療センター受診患者の実態調査 Reviewed

    国富 陽介, 植田 紘貴, 中西 泰之, 片岡 伴記, 村上 隆, 上岡 寛

    中・四国矯正歯科学会雑誌   30 ( 1 )   72 - 72   2018.8

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  • 重度の歯肉退縮および叢生を伴う骨格性III級症例の長期保定 Reviewed

    植田紘貴, 岡直毅, 村上隆, 上岡寛

    日本矯正歯科学会大会プログラム・抄録集   77th   343 - 343   2018

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  • 内臓感覚と唾液分泌および嚥下反射の関係 Reviewed

    菅 真有, 植田 紘貴, 八木 孝和, 宮脇 正一

    九州矯正歯科学会雑誌   12 ( 1 )   77 - 77   2017.3

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  • 重度の叢生を伴うMarfan症候群の一治験例 Reviewed

    菅真有, 植田紘貴, 大石章仁, 宮脇正一

    日本矯正歯科学会大会プログラム・抄録集   76th   289 - 289   2017

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  • 唾液分泌と嚥下の調節機構における内臓感覚の役割 Reviewed

    植田紘貴, 菅真有, 八木孝和, 楠本郁恵, 柏谷英樹, 桑木共之, 宮脇正一

    日本生理学雑誌(Web)   79 ( 1 )   26 - 26   2017

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  • 再生医療のこれまでとこれから 内臓感覚が唾液分泌と嚥下機能に果たす役割 Invited

    植田 紘貴, 菅 真有, 八木 孝和, 楠本 郁恵, 柏谷 英樹, 桑木 共之, 宮脇 正一

    日本再生歯科医学会誌   14 ( 1 )   40 - 40   2016.12

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  • 唾液分泌および嚥下反射の誘発に内臓感覚の賦活化が及ぼす影響 Reviewed

    植田 紘貴, 菅 真有, 八木 孝和, 宮脇 正一

    日本矯正歯科学会大会プログラム・抄録集   75回   171 - 171   2016.11

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  • 歯科矯正用アンカースクリューを用いた骨格性III級前歯部反対咬合症例の1治験例 Reviewed

    植田紘貴, 菅真有, 宮脇正一

    日本顎変形症学会雑誌   26 ( 2 )   119 - 119   2016

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  • 上下顎前突と下顎第三大臼歯の近心傾斜を伴う骨格性II級症例の一治験例 Reviewed

    植田 紘貴, 菅 真有, 北嶋 文哲, 宮脇 正一

    日本矯正歯科学会大会プログラム・抄録集   74回   316 - 316   2015.11

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  • 鹿児島大学歯学部学生のKolbの学習スタイルについて Reviewed

    植田 紘貴, 宮脇 正一, 菅 真有, 池森 宇泰, 田口 則宏

    日本歯科医学教育学会総会・学術大会プログラム・抄録集   34回   107 - 107   2015.7

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  • 唾液分泌はいかに制御されるか? 内臓感覚と胃酸分泌抑制剤ニザチジンの新たな関係 Reviewed

    植田 紘貴, 菅 真有, 八木 孝和, 大賀 泰彦, 宮脇 正一

    九州矯正歯科学会雑誌   10 ( 1 )   36 - 36   2014.12

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  • 従来の大臼歯遠心移動装置とスケレタルアンカレッジ装置の治療効果の検討 系統的レビュ Reviewed

    八木 孝和, 菅 真有, 植田 紘貴, 友成 博, 大牟禮 治人, 宮脇 正一

    日本矯正歯科学会大会プログラム・抄録集   73回   235 - 235   2014.10

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  • 胃酸分泌抑制と唾液分泌促進の二相性効果について H2受容体拮抗薬による自律神経活動の促進 Reviewed

    植田 紘貴, 菅 真有, 八木 孝和, 宮脇 正一

    日本矯正歯科学会大会プログラム・抄録集   73回   179 - 179   2014.10

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  • 【酸蝕症を考える(1)総論編】 酸蝕症とブラキシズム Invited Reviewed

    小児歯科臨床   19 ( 5 )   38 - 42   2014.5

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  • 顎変形症患者の心理 顎変形症患者の心理と行動変容プロセスについて Invited

    植田 紘貴

    日本顎変形症学会雑誌   24 ( 2 )   98 - 98   2014.5

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  • Report of curriculum improvement working group in Kagoshima University Faculty of Dentistry Reviewed

    MIYAWAKI Shouichi, UEDA Hirotaka, MATSUYAMA Takashi, SATO Tsuyoshi, TOKUDA Masayuki, YAMANAKA Atsushi, MINE Kazuharu, OHNISHI Tomokazu, KAWADA-MATSUO Miki, YAMAGUCHI Taihei, IWASAKI Tomonori, SAKOGUCHI Kenji, KAMASHITA Yuji, NITTA Tetsuya, HIJIOKA hiroshi, KOHJITANI Atsushi, NISHIMURA Masahiro, KUKUCHI Masafumi, TAGUCHI Norihiro, SATO Tomoaki

    鹿児島大学歯学部紀要   34   107 - 111   2014

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  • International partnership between the Faculty of Dentistry, Kagoshima University and the Faculty of Dentistry, Airlangga University (1) Reviewed

    MIYAWAKI Shouichi, UEDA Hirotaka, YAGI Takakazu, YAMAMOTO Yoshitake, TOMONARI Hiroshi, MAEDA Aya, KAMIMURA Hiroki, NAGAYAMA Kunihiro, KUNINORI Takaharu, TAKADA Hiroko, UEHARA Sawako, YOSHIDA Reiko, SHIMADA Kazuyuki

    34   79 - 82   2014

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  • 臨床教育部会報告 鹿児島大学歯学部における臨床教育-現状と今後の方向性について- Reviewed

    田口則宏, 中村典史, 西村正宏, 嶺崎良人, 岩崎智憲, 糀谷淳, 山口泰平, 作田哲也, 武内博信, 門川明彦, 丸山浩美, 今村晴幸, 大河内孝子, 深水篤, 植田紘貴, 末永重明, 諏訪素子

    鹿児島大学歯学部紀要   34   103 - 106   2014

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  • A report of international symposium of globalization in dental medical education and research Reviewed

    Hirotaka UEDA

    鹿児島大学歯学部紀要   34   133 - 135   2014

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  • 胃食道逆流モデルラットを用いた胃酸分泌抑制剤の唾液分泌促進作用の解明 Reviewed

    菅 真有, 植田 紘貴, 八木 孝和, 宮脇 正一

    九州矯正歯科学会雑誌   9 ( 1 )   61 - 61   2013.12

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  • 胃酸分泌抑制剤ニザチジンの唾液分泌促進剤としての可能性 中枢への作用と内臓感覚との関連 Reviewed

    植田 紘貴, 菅 真有, 八木 孝和, 宮脇 正一

    日本矯正歯科学会大会プログラム・抄録集   72回   157 - 157   2013.10

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  • 胃酸分泌抑制剤ニザチジンの唾液分泌促進作用について Reviewed

    植田 紘貴, 菅 真有, 八木 孝和, 宮脇 正一

    Journal of Oral Biosciences Supplement   2013   153 - 153   2013.9

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  • 唇顎口蓋裂を伴う矯正患者の保護者における心理状態と関心事 Reviewed

    福重 雅美, 帆北 友紀, 前田 綾, 植田 紘貴, 上原 沢子, 下田平 貴子, 宮脇 正一

    日本歯科衛生学会雑誌   8 ( 1 )   129 - 129   2013.8

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  • Research activity report - Department of Orthodontics -

    Miyawaki Shouichi, Ohmure Haruhito, Yagi Takakazu, Sakaguchi Katsuyoshi, Yamamoto Yoshitake, Tomonari Hiroshi, Maeda Aya, Kamimura Hiroki, Nagayama Kunihiro, Ueda Hirotaka

    33   71 - 73   2013.3

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  • 増える逆流性食道炎 ご存知ですか?口腔内疾患との密接な関係 PART3 逆流性食道炎と歯科とのかかわり Invited

    宮脇正一, 植田紘貴, 前田綾

    歯科衛生士   37 ( 6 )   80 - 83   2013

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  • 矯正治療を受けている唇顎口蓋裂を伴う児童の保護者の心理状態と関心事の解明. Reviewed

    前田 綾, 植田 紘貴, 上原 沢子, 宮脇 正一

    かごしま口腔保健協会会報   31   6 - 7   2013

  • 胃酸分泌抑制剤ニザチジンの唾液分泌促進作用について Reviewed

    植田紘貴, 菅真有, 八木孝和, 宮脇正一

    Journal of Oral Biosciences Supplement (Web)   2013   2013

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  • 唾液分泌と迷走神経の関連性 Reviewed

    植田 紘貴, 八木 孝和, 菅 真有, 宮脇 正一

    九州矯正歯科学会雑誌   8 ( 1 )   89 - 89   2012.12

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  • 歯科矯正学に関する1回の講義が学生のボディーイメージに及ぼす影響について 理系学生と文系学生の比較 Reviewed

    植田 紘貴, 宮脇 正一, 上原 沢子, 菅 真有, 池森 宇泰, 佐藤 友昭, 田口 則宏

    日本矯正歯科学会大会プログラム・抄録集   71回   202 - 202   2012.9

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  • 内臓感覚は唾液分泌および顎舌骨筋のリズミカルな筋活動を誘発する Reviewed

    植田 紘貴, 八木 孝和, 菅 真有, 宮脇 正一

    日本矯正歯科学会大会プログラム・抄録集   71回   148 - 148   2012.9

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  • 唾液分泌動態は迷走神経の一過性の刺激により促進される Reviewed

    植田 紘貴, 八木 孝和, 菅 真有, 宮脇 正一

    日本矯正歯科学会大会プログラム・抄録集   70回   214 - 214   2011.10

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  • 歯周病原性因子存在下の培養ヒト歯根膜線維芽細胞への物理的刺激による細胞内シグナル伝達系の動態検討 Reviewed

    八木孝和, 前田綾, 植田紘貴, 菅真有, 宮脇正一

    日本矯正歯科学会大会プログラム・抄録集   70th   248 - 248   2011

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  • 小・中学生の問題行動と睡眠、胃食道逆流症状に関する因子の検討 Reviewed

    坂口 勝義, 兼松 恭子, 齋藤 陽子, 永山 邦宏, 植田 紘貴, 大牟禮 治人, 宮脇 正一

    日本矯正歯科学会大会プログラム・抄録集   69回   220 - 220   2010.9

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  • 【子どもの歯ぎしり】 睡眠時ブラキシズムに対する考え方 Invited

    宮脇 正一, 永山 邦宏, 植田 紘貴, 大牟禮 治人, 坂口 勝義

    小児歯科臨床   15 ( 8 )   12 - 26   2010.8

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  • 小児における問題行動と睡眠障害;睡眠時ブラキシズムおよび胃食道逆流との関連について Reviewed

    93 ( 672 )   8 - 10   2010

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  • 口腔乾燥症治療薬セビメリンはラット上唾液核ニューロンの興奮性を促進する Reviewed

    植田 紘貴, 美藤 純弘, 市川 博之, 小橋 基, 山城 隆, 松尾 龍二

    日本矯正歯科学会大会プログラム・抄録集   68回   144 - 144   2009.11

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  • ラット上唾液核ニューロンに対するセビメリンの興奮性作用に関する電気生理学的および免疫組織化学的解析 Reviewed

    植田 紘貴, 美藤 純弘, 市川 博之, 小橋 基, 山城 隆, 松尾 龍二

    Journal of Oral Biosciences   51 ( Suppl. )   151 - 151   2009.8

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  • CEVIMELINE ENHANCES THE EXCITABILITY IN THE RAT SUPERIOR SALIVATORY NUCLEUS NEURONS Reviewed

    Hirotaka Ueda, Yoshihiro Mitoh, Hiroyuki Ichikawa, Motoi Kobashi, Takashi Yamashiro, Ryuji Matsuo

    JOURNAL OF PHYSIOLOGICAL SCIENCES   59   142 - 142   2009

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  • セビメリンはラット上唾液核ニューロンの興奮性を促進する Reviewed

    植田 紘貴, 藤井 昭仁, 美藤 純弘, 兒玉 直紀, 小橋 基, 山城 隆, 松尾 龍二

    Journal of Oral Biosciences   50 ( Suppl. )   144 - 144   2008.9

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  • 骨芽細胞株MC3T3-E1細胞において流体剪断応力はMAPKを介してCTGFの発現を増大させる Reviewed

    本城正, 植田紘貴, 上岡寛, 山城隆, 山本照子

    日本矯正歯科学会大会プログラム・抄録集   66th   147 - 147   2007

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  • 術前矯正にチタンスクリューを用いて下顎右側第二、第三大臼歯を近心移動した骨格性下顎前突症例 Reviewed

    福永 智広, 黒田 晋吾, 植田 紘貴, 山本 照子

    日本矯正歯科学会大会プログラム・抄録集   65回   290 - 290   2006.9

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Presentations

  • The effect of KATP channel modulators on taste sensitivity in mice

    Chika Sawai, Kengo Horie, Yoshihiro Mitoh, Hirotaka Ueda, Hiroshi Kamioka

    APPW2025  2025.3.18 

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  • Digital optical impressions to fabricate safe and accurate devices for patient with CLCP: practical cases in Okayama University Hospital International conference

    Hirotaka UEDA, Gohji KOZAKI, Shigetomo TSUJI, Yuki ARIMURA, Takaya SENOO, Seiji IIDA, Hiroshi KAMIOKA

    CLEFT TOKYO 2024  2024.7.18 

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    Event date: 2024.7.17 - 2024.7.19

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  • Effects of cervical vagal nerve stimulation on respiration and blood pressure variability and tissue blood flow in salivary gland

    Hirotaka Ueda, Yoshihiro Mitoh, Hiroshi Kamioka, Ryusuke Yoshida

    2024.3.30 

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    Event date: 2024.3.28 - 2024.3.30

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  • Intraoral and Perinasal Digital Impression to create PNAM in a Neonate with Unilateral Cleft Lip and Palate

    Hirotaka Ueda, Shigetomo Tsuji, Masahiro Nakamura, Hiroshi Kamioka

    14th International Cleft Congress (CLEFT 2022)  2022.7.11 

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    Event date: 2022.7.11 - 2022.7.15

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  • A TMD Ⅲb case with retrognathia, open-bite treated with segmental Le Fort I and BSSO

    Fumiko Takemoto, Hirotaka Ueda, Miku Yasumitsu, Akiyoshi Nishiyama, Soichiro Ibaragi, Hiroshi Kamioka

    The 35th Annual Meeting of the Japanese Society for Jaw Deformities  2025.6.4 

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  • A case of mandibular prognathism carrying deep curve of Spee treated by two-stage osteotomies of Kole and Le Fort I / genioplasty

    Kazuki Nakatsuji, Katsuhiko Amano, Saori Tanizaki, Yuki Arimura, Shou Akashi, Yuki Nagata, Hirotaka Ueda, Hiroshi Kamioka, Seiji Iida

    The 35th Annual Meeting of the Japanese Society for Jaw Deformities  2025.6.4 

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    The 83rd Annual Meeting of the Japanese Orthodontic Society  2024.10.31 

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    Hirotaka Ueda, Kana Kono, Fumiko Takemoto, Takashi Izawa, Hiroshi Kamioka

    The 83rd Annual Meeting of the Japanese Orthodontic Society  2024.10.31 

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  • 下顎歯列弓幅径が過大な骨格性下顎前突症に対し上顎正中三分割術により上顎の拡大を施行した一例

    穴田 理嵯, 早野 暁, 西山 明慶, 植田 紘貴, 伊原木 聰一郎, 上岡 寛

    第83回日本矯正歯科学会学術大会 2024年10月31日  2024.10.31 

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  • A clinical application of optical impression for replacing a PLP with an expanding plate with bulb

    Gohji Kozaki, Hirotaka Ueda, Yuki Arimura, Seiji Iida, Hiroshi Kamioka

    The 67th annual meeting of Chu-Shikoku Orthodontic Society (Hiroshima)  2024.7.7 

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  • .

    Hirotaka Ueda

    2024.7.7 

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    Language:Japanese   Presentation type:Oral presentation (general)  

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  • An asymmetry and prognathism with ristricted jaw movement treated by Le Fort I and IVRO

    Fumiko Takemoto, Hirotaka Ueda, Akiyoshi Nishiyama, Soichiro Ibaragi, Hiroshi Kamioka

    2024.6.28 

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    Event date: 2024.6.27 - 2024.6.28

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  • Distraction osteogenesis for underdeveloped maxilla in patient with cleft lip and palate

    Yuki Arimura, Katsuhiko Amano, Kazuki Nakatsuji, Yuki Nagata, Soma Kato, Hirotaka Ueda, Hiroshi Kamioka, Seiji lida

    2024.6.27 

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    Event date: 2024.6.27 - 2024.6.28

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  • A case of cleft palate treated by maxillary distraction osteogenesis with evaluation of velopharyngeal function

    Hirotaka Ueda, Naoki Oka, Yasuyuki Nakanishi, Yuki Arimura, Seiji lida, Hiroshi Kamioka

    2024.6.27 

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  • Unilateral transverse maxillary distraction osteogenesis for UCLP patients

    Yuki Nishiya, Yuki Arimura, Katsuhiko Amano, Aiko Hyodo, Hirotaka Ueda, Kana Kouno, Kaori Okubo, Fumiko Takemoto, Hiroshi Kamioka, Seiji Iida

    The 48th Annual Meeting ofJapanese Cleft Palate Association  2024.5.30 

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  • Effect on an optical impression to enhance stability of the maxillary anterior segment after MASDO

    Fumiko Takemoto, Hirotaka Ueda, Yasuyuki Nakanishi, Yuki Nishiya, Aiko Hyodo, Yuki Arimura, Seiji Iida, Hiroshi Kamioka

    The 48th Annual Meeting of Japanese Cleft Palate Association  2024.5.30 

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  • A case of Robin sequence with unitreated palatal plastic surgery using speech id and bulb

    Risa Anada, Hirotaka Ueda, Takayuki Konishi, Atsuko Nakagawa, Seiji Iida, Hiroshi Kamioka

    The 48th Annual Meeting of Japanese Cleft Palate Association  2024.5.30 

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  • A case of connective tissue graft for a moderate crowding with gingival recession

    HASHIMOTO M, UEDA H, OKUBO K, KAMIOKA H

    The 82nd Annual Meeting of the Japanese Orthodontic Society  2023.11.2 

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  • Trial of PLP for patients with submucosal cleft palate using an oral scanner

    KOZAKI G, UEDA H, KAMIOKA H

    The 82nd Annual Meeting of the Japanese Orthodontic Society  2023.11.2 

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    The18th annual meeting of The Japan Society for Dental Hygiene  2023.9.17 

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  • A statistical study of the patients in Okayama University Hospital Advanced CLCP Treatment Center

    Yuri Yoshikawa, Hirotaka Ueda, Yuki Arimura, Seiji Iida, Hiroshi Kamioka

    2023.7.1 

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  • 顎関節症状を伴う顔面非対称症例に対して Le FortI型骨切り術とIVSRO を施行した一治験例

    田中敦子, 植田紘貴, 石田朋子, 中辻和樹, 森谷徳文, 飯田征二, 上岡寛

    第33回日本顎変形症学会総会・学術大会  2023.6.9 

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  • 早期開口訓練により下顎枝垂直骨切り術後のcondylar sagの改善を図った骨格性下顎前突症の一治験例

    石田朋子, 植田紘貴, 有村友紀, 森谷徳文, 飯田征二, 上岡 寛

    第33回日本顎変形症学会総会・学術大会  2023.6.8 

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    Event date: 2023.6.8 - 2023.6.9

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  • 複合的な要因を有する骨格性下顎骨後退症例に対して下顎骨前方移動術を施行し機能的改善を認めたー治験例

    中西泰之, 植田紘貴, 吉岡徳枝, 伊原木聰一郎, 上岡寛

    第33回日本顎変形症学会総会・学術大会  2023.6.8 

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  • 上顎骨の著しい狭窄と交叉咬合を伴う両側性唇顎口蓋裂症例に骨延長術を施行した一治験例

    竹本史子, 植田紘貴, 中西泰之, 岡直毅, 岩本悠希, 三上彩可, 兵藤藍子, 有村友紀, 飯田征二, 上岡寛

    第47回日本口蓋裂学会総会・学術集会  2023.5.25 

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  • 岡山大学病院口唇裂・口蓋裂総合治療センターにおける受診患者の臨床統計的調査

    吉川友理, 植田紘貴, 中西泰之, 有村友紀, 妹尾貴矢, 木股敬裕, 飯田征二, 上岡寛

    第47回日本口蓋裂学会総会・学術集会  2023.5.25 

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  • NSAIDs系鎮痛薬の常用による歯の移動の遅延を認めた上下顎前突症例の一治験例

    中西 泰之, 植田 紘貴, 星島 光博, 井澤 俊, 上岡 寛

    第81回日本矯正歯科学会  2022.10.6 

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    Event date: 2022.10.5 - 2022.10.7

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  • 外科的矯正治療を行った症候群性頭蓋縫合早期癒合症患者の長期経過を追った3症例

    河野 加奈, 村上 隆, 植田 紘貴, 片岡 伴記, 川邉 紀章, 原 規子, 大住 隆太, 上岡 寛

    第81回日本矯正歯科学会  2022.10.6 

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    Event date: 2022.10.5 - 2022.10.7

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  • 上顎骨のカントを伴う下顎骨偏位症例において非外科的に咬合を確立し良好な長期的予後を得た一治験例

    中逵 敬太, 植田 紘貴, 村上 隆, 上岡 寛

    第81回日本矯正歯科学会  2022.10.6 

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    Event date: 2022.10.5 - 2022.10.7

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  • A case of mandibular retrognathia with complex factors treated by mandibular advancement.

    Yasuyuki Nakanishi, Hirotaka Ueda, Masahiro Nakamura, Hiroshi Kamioka

    65th Chu-Shikoku Orthodontic Society Annual Meeting  2022.7.2  Chu-Shikoku Orthodontic Society

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    Event date: 2022.7.2 - 2022.7.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Fukuyama, Hiroshima   Country:Japan  

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    Risa Anada, Hirotaka Ueda, Norifumi Moritani, Tatsushi Matsumura, Seiji Iida, Hiroshi Kamioka

    The 32nd Annual Meeting of the Japanese Society for Jaw Deformities  2022.6.8 

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    Event date: 2022.6.8 - 2022.6.10

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  • A case of orthognathic surgery for skeletal mandibular retrognathia with temporomandibular joint disorder

    Naoki Oka, Hirotaka Ueda, Norifumi Moritani, Tatsushi Matsumura, Seiji Iida, Hiroshi Kamioka

    The 32nd Annual Meeting of the Japanese Society for Jaw Deformities  2022.6.8 

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    Event date: 2022.6.8 - 2022.6.10

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  • Comparison of hard-soft tissue changes after MASDO and mandibular osteotomy in patients with CLP

    2022.5.26 

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    Event date: 2022.5.26 - 2022.5.27

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 術前後にナゾメーターで鼻咽腔閉鎖機能を評価して上顎骨仮骨延長術を施行した口蓋裂症例の一治験例

    岡直毅, 植田紘貴, 中逵敬太, 中西泰之, 三上彩可, 兵藤藍子, 安富成美, 薬師寺翔太, 有村友紀, 古西隆之, 飯田征二, 上岡寛

    第46回日本口蓋裂学会  2022.5.26 

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    Event date: 2022.5.26 - 2022.5.27

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  • 健側の上顎右側側切歯の先天性欠如と上顎歯列正中の一歯分の右方偏位を伴う左側唇顎口蓋裂症例の一治験例

    太田明美, 植田紘貴, 中西泰之, 安富成美, 有村友紀, 飯田征二, 上岡寛

    第46回日本口蓋裂学会  2022.5.26 

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  • 著しい成長障害を生じた中間顎を有する両側性唇顎口蓋裂患者に対して骨延長術を用いた外科矯正的アプローチ

    兵藤藍子, 有村友紀, 植村亜由美, 薬師寺翔太, 安富成美, 三上彩可, 大久保(田畑)香織, 植田紘貴, 上岡寛, 飯田征二

    第46回日本口蓋裂学会  2022.5.26 

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    Event date: 2022.5.26 - 2022.5.27

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  • 鼻部と口蓋の一体的な光学印象を活用したPNAM作製の試みについて

    辻重智, 植田紘貴, 中村政裕, 上岡寛

    第46回日本口蓋裂学会  2022.5.26 

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  • 岡山大学病院矯正歯科における永久歯先天性欠如の調査

    星島 光博, 出射 明美, 中西 泰之, 植田 紘貴, 早野 暁, 上岡 寛

    第二回せとうち臨床遺伝研究会  2022.4.10 

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  • A functional cross-bite with restricted maxillary arch and midline deviation improved by rapid maxillary expansion

    Hirotaka Ueda, Yuki Namba, Naoki Oka, Takashi Yamashiro, Hiroshi Kamioka

    The 80th Annual Meeting of the Japanese Orthodontic Society  2021.11.4 

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    Event date: 2021.11.3 - 2021.11.5

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  • 眼性斜頸を伴う上顎咬合平面の傾斜及び顔面非対称を呈した成長期患者の一治験例

    植田 紘貴、難波 裕生、山城 隆、上岡 寛

    第31回日本顎変形症学会総会・学術大会  2021.6.11 

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    Event date: 2021.6.11 - 2021.6.12

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  • 岡山大学病院口唇裂・口蓋裂総合治療センター矯正歯科にて咬合管理を開始した患者動態について

    植田 紘貴 、岡 直毅、中村 政裕、有村 友紀、徳山 英二郎、妹尾 貴矢、松村 達志、木股 敬裕、飯田 征二、上岡 寛

    第45回日本口蓋裂学会総会・学術集会  2021.5.20 

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    Event date: 2021.5.20 - 2021.5.21

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  • 成人期に顎裂部に再骨移植術を行い咬合の長期安定性を認めた左側唇顎口蓋裂を伴う下顎前突症の一治験例

    植田 紘貴、谷崎 沙織、岡 直毅、飯田 征二、木股 敬裕、山城 隆、上岡 寛

    第45回日本口蓋裂学会総会・学術集会  2021.5.20 

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    Event date: 2021.5.20 - 2021.5.21

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  • Patient distribution managed by Orthodontics in Okayama University Hospital Advanced CLCP Center

    植田紘貴, 植田紘貴, 岡直毅, 中村政裕, 中村政裕, 有村友紀, 有村友紀, 徳山英二郎, 徳山英二郎, 妹尾貴矢, 妹尾貴矢, 松村達志, 松村達志, 木股敬裕, 木股敬裕, 飯田征二, 飯田征二, 上岡寛, 上岡寛

    2021.5.20  Japanese Cleft Palate Association

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    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

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  • 下顎枝垂直骨切り術後に下顎頭の前方・側方滑走運動量の増加と関節雑音の消退を認めた骨格性下顎前突症例

    植田 紘貴、岡 直毅、森谷 徳文、松村 達志、飯田 征二、上岡 寛

    第30回日本顎変形症学会総会・学術大会  2020.6.24 

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    Event date: 2020.7.9

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  • ホッツ床の即日装着の試みについて

    植田 紘貴, 国富 陽介, 中西 泰之, 片岡 伴記, 村上 隆, 徳山 英二郎, 上岡 寛

    第44回日本口蓋裂学会総会・学術集会  2020.6.4 

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  • Clinical investigation of patients with cleft lip and palate treated by Maxillary Anterior Segmental Distraction Osteogenesis (MASDO)

    Narumi Okamto, Tatsushi Matsumura, Yuki Arimura, Shouta Yakushiji, Hirotaka Ueda, Hiroshi Kamioka, Seiji Iida

    The 44th Annual Meeting of Japanese Cleft Palate Association  2020.6.4  Japanese Cleft Palate Association

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    Event date: 2020.6.4 - 2020.6.5

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

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  • Psychological status of patients with jaw deformities Invited

    Hirotaka Ueda

    The 24th Annual Meeting of the Japanese Society for Jaw Deformities  2014.6.11 

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    Event date: 2014.6.10 - 2014.6.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

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  • Facial asymmetry with irreducible anterior disc displacement on the mandibular deviated side treated by IVRO

    Hirotaka Ueda

    Japanese Orthodontic Society  2019.11.20 

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  • A case report of patient with Apert syndrome treated with Le Fort I osteotomy, Le Fort III osteotomy after skull angioplasty

    2019.7.7 

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  • スプリントによる下顎位確認後に下顎枝垂直骨切り術を行い偏位側への側方滑走運動が改善した顔面非対称症例

    植田 紘貴, 岡 直毅, 上岡 寛

    第29回日本顎変形症学会総会・学術大会(東京都千代田区)  2019.6.8 

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  • A statistical study of the patients in Okayama University Hospital Advanced CLCP Center

    2019.5.30 

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  • 重度の歯肉退縮および叢生を伴う骨格性III級症例の長期保定

    植田紘貴, 岡 直毅, 村上隆, 上岡 寛

    第77回日本矯正歯科学会学術大会(神奈川県横浜市)  2018.11.1 

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  • 重度の歯のフッ素症に対し歯面処理効果を確認した上顎前突症例

    田畑香織, 植田紘貴, 石本和也, 上岡 寛

    第77回日本矯正歯科学会学術大会(神奈川県横浜市)  2018.11.1 

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  • 過去3年間における岡山大学病院口唇裂・口蓋裂総合治療センター受診患者の実態調査

    国富陽介, 植田紘貴, 中西泰之, 片岡伴記, 村上隆, 上岡寛

    第61回中・四国矯正歯科学会大会(岡山県岡山市)  2018.7.7 

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  • 重度の叢生を伴うMarfan症候群の一治験例

    菅 真有, 植田紘貴, 大石章仁, 宮脇正一

    第76回日本矯正歯科学会学術大会(北海道札幌市)  2017.10.18 

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  • 内臓感覚と唾液分泌および嚥下反射の関係

    菅真有, 植田紘貴, 八木孝和, 宮脇正一

    九州矯正歯科学会雑誌  2017.3.31 

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  • 唾液分泌と嚥下の調節機構における内臓感覚の役割

    植田紘貴, 菅真有, 八木孝和, 楠本郁恵, 柏谷英樹, 桑木共之, 宮脇正一

    日本生理学雑誌(Web)  2017.2 

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  • 唾液分泌および嚥下反射の誘発に内臓感覚の賦活化が及ぼす影響

    植田紘貴, 菅真有, 八木孝和, 宮脇正一

    日本矯正歯科学会大会プログラム・抄録集  2016.11 

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  • 内臓感覚が唾液分泌と嚥下機能に果たす役割

    植田紘貴, 菅真有, 八木孝和, 楠本郁恵, 柏谷英樹, 桑木共之, 宮脇正一

    日本再生歯科医学会シンポジウム要旨集  2016.7.18 

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  • 歯科矯正用アンカースクリューを用いた骨格性III級前歯部反対咬合症例の1治験例

    植田紘貴, 菅真有, 宮脇正一

    日本顎変形症学会雑誌  2016.5.25 

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  • 上下顎前突と下顎第三大臼歯の近心傾斜を伴う骨格性II級症例の一治験例

    植田紘貴, 菅真有, 北嶋文哲, 宮脇正一

    日本矯正歯科学会大会プログラム・抄録集  2015.11 

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  • 鹿児島大学歯学部学生のKolbの学習スタイルについて

    植田紘貴, 宮脇正一, 菅真有, 池森宇泰, 田口則宏

    日本歯科医学教育学会総会・学術大会プログラム・抄録集  2015.7 

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  • 唾液分泌はいかに制御されるか?―内臓感覚と胃酸分泌抑制剤ニザチジンの新たな関係―

    植田紘貴, 菅真有, 八木孝和, 大賀泰彦, 宮脇正一

    九州矯正歯科学会雑誌  2014.12.31 

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  • 胃酸分泌抑制と唾液分泌促進の二相性効果について-H2受容体拮抗薬による自律神経活動の促進-

    植田紘貴, 菅真有, 八木孝和, 宮脇正一

    日本矯正歯科学会大会  2014.10.20  (公社)日本矯正歯科学会

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  • 従来の大臼歯遠心移動装置とスケレタルアンカレッジ装置の治療効果の検討-系統的レビュー-

    八木孝和, 菅真有, 植田紘貴, 友成博, 大牟禮治人, 宮脇正一

    日本矯正歯科学会大会プログラム・抄録集  2014.10.20  (公社)日本矯正歯科学会

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    Venue:千葉県千葉市   Country:Japan  

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  • 従来の大臼歯遠心移動装置とスケレタルアンカレッジ装置の治療効果の検討―系統的レビュー―

    八木孝和, 菅真有, 植田紘貴, 友成博, 大牟禮治人, 宮脇正一

    日本矯正歯科学会大会プログラム・抄録集  2014.10 

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  • 胃酸分泌抑制と唾液分泌促進の二相性効果について―H2受容体拮抗薬による自律神経活動の促進―

    植田紘貴, 菅真有, 八木孝和, 宮脇正一

    日本矯正歯科学会大会プログラム・抄録集  2014.10 

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  • 顎変形症患者の心理と行動変容プロセスについて

    植田紘貴

    日本顎変形症学会雑誌  2014.5.15 

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  • 胃食道逆流モデルラットを用いた胃酸分泌抑制剤の唾液分泌促進作用の解明

    菅真有, 植田紘貴, 八木孝和, 宮脇正一

    九州矯正歯科学会雑誌  2013.12.31 

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  • 胃酸分泌抑制剤ニザチジンの唾液分泌促進作用について

    植田 紘貴, 菅 真有, 八木 孝和, 宮脇 正一

    Journal of Oral Biosciences Supplement  2013.9 

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  • 唇顎口蓋裂を伴う矯正患者の保護者における心理状態と関心事

    福重雅美, 帆北友紀, 前田綾, 植田紘貴, 上原沢子, 下田平貴子, 宮脇正一

    日本歯科衛生学会雑誌  2013.8.10 

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  • 胃酸分泌抑制剤ニザチジンの唾液分泌促進剤としての可能性-中枢への作用と内臓感覚との関連-

    植田紘貴, 菅真有, 八木孝和, 宮脇正一

    日本矯正歯科学会大会プログラム・抄録集  2013  (公社)日本矯正歯科学会

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  • 唾液分泌と迷走神経の関連性

    植田紘貴, 八木孝和, 菅真有, 宮脇正一

    九州矯正歯科学会雑誌  2012.12.31 

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  • 内臓感覚は唾液分泌および顎舌骨筋のリズミカルな筋活動を誘発する

    植田紘貴, 八木孝和, 菅真有, 宮脇正一

    日本矯正歯科学会大会プログラム・抄録集  2012.9 

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  • 歯科矯正学に関する1回の講義が学生のボディーイメージに及ぼす影響について 理系学生と文系学生の比較

    植田 紘貴, 宮脇 正一, 上原 沢子, 菅 真有, 池森 宇泰, 佐藤 友昭, 田口 則宏

    日本矯正歯科学会大会プログラム・抄録集  2012.9 

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  • 歯周病原性因子存在下の培養ヒト歯根膜線維芽細胞への物理的刺激による細胞内シグナル伝達系の動態検討

    八木孝和, 前田綾, 植田紘貴, 菅真有, 宮脇正一

    日本矯正歯科学会大会プログラム・抄録集  2011.10 

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  • 唾液分泌動態は迷走神経の一過性の刺激により促進される

    植田紘貴, 八木孝和, 菅真有, 宮脇正一

    日本矯正歯科学会大会プログラム・抄録集  2011.10 

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  • 歯列後方部の萌出スペースを考慮した治療計画の立案

    上村裕希, 友成博, 植田紘貴, 兼松恭子, 北嶋文哲, 迫口陽子, 上原沢子, 菅真有, 宮脇正一

    第6 回九州矯正歯科学会  2011.2 

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  • 小・中学生の問題行動と睡眠・胃食道逆流症状に関する因子の検討

    坂口勝義, 兼松恭子, 齋藤陽子, 永山邦宏, 植田紘貴, 大牟禮治人, 宮脇正一

    日本矯正歯科学会大会プログラム・抄録集  2010.9 

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  • ラット顎下腺・舌下腺支配の上唾液核ニューロンに対するセビメリンの作用機序

    美藤純弘, 植田紘貴, 市川博之, 藤田雅子, 山城 隆, 小橋 基, 松尾龍二

    第19 回神経行動薬理若手研究者の集い  2010.3 

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  • 口腔乾燥症治療薬セビメリンはラット上唾液核ニューロンの興奮性を促進する

    植田紘貴, 美藤純弘, 市川博之, 小橋基, 山城隆, 松尾龍二

    日本矯正歯科学会大会プログラム・抄録集  2009.11 

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  • ラット上唾液核ニューロンに対するセビメリンの興奮性作用に関する電気生理学的および免疫組織化学的解析

    植田紘貴, 美藤純弘, 市川博之, 小橋基, 山城隆, 松尾龍二

    J Oral Biosci  2009.8.10 

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  • Cevimeline enhances the excitability in the rat superior salivatory nucleus neurons International conference

    Hirotaka Ueda, Yoshihiro Mitoh, Hiroyuki Ichikawa, Motoi Kobashi, Takashi Yamashiro, Ryuji Matsuo

    The 36th Congress of the International Union of Physiological Sciences(IUPS2009)  2009.7 

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  • Cevimeline enhances the excitability in the rat superior salivatory neurons International conference

    Hirotaka Ueda, Yoshihiro Mitoh, Hiroyuki Ichikawa, Motoi Kobashi, Takashi Yamashiro, Ryuji Matsuo

    The 11th International Symposium on Exocrine Secretion  2009.7 

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  • セビメリンはラット上唾液核ニューロンの興奮性を促進する

    植田紘貴, 藤井昭仁, 美藤純弘, 兒玉直紀, 小橋基, 山城隆, 松尾龍二

    J Oral Biosci  2008.9.10 

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  • 骨芽細胞株MC3T3-E1細胞において流体剪断応力はMAPKを介してCTGFの発現を増大させる

    本城正, 植田紘貴, 上岡寛, 山城隆, 山本照子

    日本矯正歯科学会大会プログラム・抄録集  2007 

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  • 術前矯正にチタンスクリューを用いて下顎右側第二,第三大臼歯を近心移動した骨格性下顎前突症例

    福永智広, 黒田晋吾, 植田紘貴, 山本照子

    日本矯正歯科学会大会プログラム・抄録集  2006.9 

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Industrial property rights

  • 分泌促進装置

    宮脇 正一, 植田, 紘貴 菅, 真有, 永山, 邦宏, 八木, 孝和, 大石, 章仁, 桑木, 共之, 池田, 正徳, 坂本, 泰二, 田松 裕一

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    Applicant:国立大学法人 鹿児島大学

    Application no:特願2017-075111  Date applied:2017.4.5

    Announcement no:特開2018-175044  Date announced:2018.11.15

    Date published:20181115

    Patent/Registration no:特許第6854513号  Date registered:2021.3.18 

    Rights holder:宮脇 正一;植田;紘貴 菅;真有;永山;邦宏;八木;孝和;大石;章仁;桑木;共之;池田;正徳;坂本;泰二;田松 裕一

    J-GLOBAL

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Awards

  • Poster award

    2024.6   Japanese Cleft Palate Association   Unilateral transverse maxillary distraction osteogenesis for UCLP patients

    Yuki Nishiya, Yuki Arimura, Katsuhiko Amano, Aiko Hyodo, Hirotaka Ueda, Kana Kouno, Kaori Okubo, Fumiko Takemoto, Hiroshi Kamioka, Seiji Iida

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  • Poster award

    2024.6   The Japanese Society for Jaw Deformities  

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  • 2016〜2017, Best researcher award(Kagoshima University

    2017.9  

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  • 口腔先端科学教育研究センター若手研究者優秀賞 (鹿児島大学大学院医歯学総合研究科)

    2016.12   『迷走神経の求心性刺激は唾液分泌と嚥下様運動を誘発する』

    植田 紘貴

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  • 優秀ポスター発表賞

    2013.10   日本矯正歯科学会   『胃酸分泌抑制剤ニザチジンの唾液分泌促進剤としての可能性ー中枢への作用と内臓感覚との関連ー』

    植田 紘貴

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  • 生理学部門優秀ポスター発表賞

    2008.9   歯科基礎医学会   『セビメリンはラット上唾液核ニューロンの興奮性を促進する』

    植田 紘貴

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Research Projects

  • 非侵襲的自律神経刺激法によるうつ症状改善方法の探索とその機序の解明

    Grant number:24K13179  2024.04 - 2027.03

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    楠元 淳也, 植田 紘貴, 大賀 泰彦, 宮脇 正一

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    Authorship:Coinvestigator(s) 

    Grant amount:\4550000 ( Direct expense: \3500000 、 Indirect expense:\1050000 )

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  • 非侵襲的な耳介迷走神経刺激は唾液分泌の促進とGERDとブラキシズムの抑制に有効か

    Grant number:23K09420  2023.04 - 2026.03

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    宮脇 正一, 植田 紘貴, 前田 綾, 大賀 泰彦, 中川 祥子, 丸谷 佳菜子, 井戸 章雄, 上村 修司

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    Grant amount:\4680000 ( Direct expense: \3600000 、 Indirect expense:\1080000 )

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  • Principal Investigator

    Grant number:22K10246  2022.04 - 2025.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)

    植田 紘貴

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    Grant amount:\4290000 ( Direct expense: \3300000 、 Indirect expense:\990000 )

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  • Elucidation of mechanosensor function acquisition process of osteocytes using 3D-volumetric image data

    Grant number:19H03859  2019.04 - 2023.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

    上岡 寛, 植田 紘貴, 早野 暁, 亀尾 佳貴, 原 徹

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    Grant amount:\17160000 ( Direct expense: \13200000 、 Indirect expense:\3960000 )

    本年度は、骨細管内の構造解析から得られた流体-構造連成解析を進めて流体応力が骨細胞の表面にどのように変形を与えているかを、共同研究者である亀尾佳貴先生を中心としたグループが国際誌Biomechanics and Modeling in Mechanobiologyに発表した。本研究では、骨細管壁と骨細胞突起を結ぶテザリングエレメントが骨細管内を流れる体液の移動で引っ張られ、細胞突起に付着する膜部位で10%を超える細胞膜変形を生じることが確認できた。この変形はメカニカルストレスにより細胞内カルシウム上昇などを生じるには十分な細胞膜変形量であることから、これら細胞突起周辺の微細構造が骨細胞の細胞突起をメカノセンサーとして重要な役割を果たしていることが示唆された。また、新たにFIB-SEM(Focused Ion Beam-Scanning Electron Microscopy)で取得した高解像度連続断層写真を用いて、これまでより広域の細胞突起の3次元形態解析を行った。得られた断層画像から細胞突起、骨細管壁を自動抽出するために機械学習を初めて応用することができた。結果、DSC(dice similarity coefficient)は、83%となり、人が手動で抽出する同等の程度まで精度を上げることができた。これにより抽出した3次元画像から形態計測を行い骨細管の微細構造を数値化することにも成功した。以上の結果をJournal of Bone and Mineral Metabolismに報告した。また、これまでの研究の成果を第80回日本矯正歯科学会学術大会で行われた日本学術会議歯学委員会臨床系歯学分科会主催の公開シンポジウム「進化・発生・メカニカルストレスから探る顎顔面形成・維持機構最先端」でシンポジストとして発表した。

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  • Principal Investigator

    Grant number:19K10405  2019.04 - 2022.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)

    植田 紘貴, 石原 嘉人, 亀田 雅博, 内部 健太, 上岡 寛

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    Grant amount:\4290000 ( Direct expense: \3300000 、 Indirect expense:\990000 )

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  • Epigenetic analysis of new bone remodeling mechanism in the dentofacial region.

    Grant number:18H03011  2018.04 - 2022.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

    Izawa Takashi

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    Grant amount:\17290000 ( Direct expense: \13300000 、 Indirect expense:\3990000 )

    It remains unclear whether the AhR signaling affects the TMJ. The aim of this study was to investigate possible mechanisms of bone loss in the TMJ due to the epigenetic alteration such as smoking. In particular, whether benzo[a]pyrene (B[a]P) induces expression of Cyp1a1 in the mandible. Possible functions of an endogenous ligand FICZ were investigated in a TMJ-OA mouse model. B[a]P was administered orally to mice and bone metabolism was examined. TMJ-OA was induced in WT mice with forceful opening of the mouth, and therapeutic functions of FICZ were detected. Exposure to B[a]P accelerated bone loss in the mandible. This bone loss manifested with osteoclastic bone resorption. In a TMJ-OA model, FICZ exhibited a dose-dependent rescue of subchondral bone loss by repressing osteoclast activity. Pretreatment with FICZ reduced RANKL-mediated osteoclastogenesis. B[a]P regulates subchondral bone metabolism via the Cyp1a1. FICZ can prevent TMJ-OA by regulating osteoclast differentiation.

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  • Considering the effects of nerves on maxillofacial formation-elucidation of the etiology of hemifacial atrophy and hemifacial hypertrophy-

    Grant number:18K09832  2018.04 - 2021.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Kawanabe Noriaki

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    Grant amount:\4420000 ( Direct expense: \3400000 、 Indirect expense:\1020000 )

    In this study, we conducted experiments to clarify the effects of the trigeminal nerve and facial nerve on the morphology of the maxillofacial region during growth. As a result of nerve activity blocking experiments and nerve activity activation experiments of the trigeminal nerve and facial nerve of rats, a decrease in the formation rate of cut teeth, calcification of the pulp, and disorder of the arrangement of ameloblasts and odontoblasts were observed. It was. In addition, as a result of analyzing Sonic hedgehog (Shh) gene-deficient mice and Shh gene-expressing mice, changes in bone and tooth morphology that are thought to be the effect of Shh on long-term maxillofacial morphogenesis were observed. As a result of conducting an experiment using fluorescence bioimaging, no characteristic stem cell dynamics were observed with or without nerve activity blocking / activation.

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  • Relationship between survey of "Stomatognathic sarcopenia" caused by malocclusion and factors of endocrine and immune system

    Grant number:16K11791  2016.04 - 2020.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Maeda-Iino Aya

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    Grant amount:\4680000 ( Direct expense: \3600000 、 Indirect expense:\1080000 )

    Recent studies have focused on the relationship between masticatory function such as MOF and body function such handgrip strength (HS). On the other hand, maximum occlusal force (MOF) is associated with maxillofacial morphology, such as high mandibular plane (Mp) angle, and with malocclusion such as open bite, posterior crossbite and scissor bite. However, the relationships between maxillofacial morphology/malocclusion and HS remain unclear. Furthermore, there is no one investigating simultaneously the relation between maxillofacial morphology, malocclusion, MOF, and HS. In this study, we found that the subjects with a large gonial angle and a small overbite or a crossbite/scissor bite in the molar section had low HS, which is related with MOF.

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  • Relationship between oral function including salivation and cognitive function: Animal model and optogenetics

    Grant number:15K20603  2015.04 - 2018.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)  Grant-in-Aid for Young Scientists (B)

    Ueda Hirotaka

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    Grant amount:\3900000 ( Direct expense: \3000000 、 Indirect expense:\900000 )

    Vagal afferent stimulation significantly increased salivation and swallowing-like events in a frequency-dependent manner. A muscle relaxant, vecuronium bromide, diminished the swallowing-like response but did not affect salivation. Moreover, the tissue blood flow rate of the body surface increased according to the frequency of the vagus nerve stimulation. These results indicate that visceral sensation induces salivation and swallowing-like events in anesthetized rodents through vagal afferent activation.
    These findings might contribute a new application of vagus nerve stimulation as to enhancing oral function.

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  • Elucidation of the relationship between the stress adjustment and the stomatognathic function by the hypothalamic-pituitary-adrenal axis and the brain-gut interactions

    Grant number:15K11349  2015.04 - 2018.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    YAGI Takakazu

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    Grant amount:\4680000 ( Direct expense: \3600000 、 Indirect expense:\1080000 )

    In order to elucidate the relationship between stress and the stomatognathic function, this study investigated the effect of the stomatognathic function caused by modulating the hypothalamus - pituitary - adrenal axis (HPA axis). As a result, the activity of the masticatory muscle electromyogram remarkably decreased from several hours immediately after administering a stress factor, adrenocorticotropin releasing factor (CRF: 1.0 nM (10 μL)) into the lateral cerebral ventricle during the light period. After this response, EMG activity showed a tendency of strong hyperactivity on the contrary. And it showed that the total EMG activity for 24 hours after administration increased relative to control group administrated the artificial cerebrospinal fluid. It also suggested that the administration of CRF into the lateral cerebral ventricle could have affected the sleep-wake rhythm.

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  • Evaluation of hypothesis which a malocclusion is caused by perception disorder and hypokinesia of pharynx, esophagus and stomach

    Grant number:25670879  2013.04 - 2015.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Challenging Exploratory Research

    MIYAWAKI Shouichi, MAEDA Aya, NAGAYAMA Kunihiro, OOMURE Haruhito, YAGI Takakazu, UEDA Hirotaka, UEHARA Sawako

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    Grant amount:\3770000 ( Direct expense: \2900000 、 Indirect expense:\870000 )

    Clinical research: we evaluated the relationship between a stomatognathic function, which closely relate with gastrointestinal function, and a malocclusion. In the patients with scissors-bite, the chewing pattern and activities of both the temporalis and the masseter muscles were significantly narrower and lower, respectively. In the patients with molar cross-bite, the reverse chewing pattern during deliberate unilateral mastication was significantly more frequently observed. Those results suggest that gastrointestinal function in patients with scissors-bite or cross-bite malocclusion may be low.
    Basic research: we focused on the vagal nerve dominating the visceral sensation. As a result of cervical vagal stimulation, it was observed the rhythmic muscle activity of mylohyoid which means swallowing with salivary secretion. From this study, it was suggested that visceral sensation is involved in activation of stomatognathic functions including salivation and swallowing.

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  • Physiological study on oral function activated by visceral sensation: brain-gut model and PET imaging

    Grant number:24792299  2012.04 - 2015.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)  Grant-in-Aid for Young Scientists (B)

    HIROTAKA Ueda

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    Grant amount:\4290000 ( Direct expense: \3300000 、 Indirect expense:\990000 )

    Gastroesophageal Reflux (GER) is a disease featured by reflux of stomach contents into the esophagus, causing chest pain and nausea by stimulation to the esophagus. Its therapy is mainly performed by acid reducer. We focused on the vagal afferent pathway mediating visceral sensation to brain. First, we investigated whether experimental stimulation affect oral function involving salivation. Next, we investigated whether acid reducer affect salivation. The present study suggested that vagal afferent stimulation evoked salivation, but also a kind of acid reducer increased salivation evoked by vagal afferent stimulation. Therefore, it was suggested that visceral sensation related to oral function involving salivation.

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  • The study of the mechanism of the stomatognathic function activated by the brain and the gastrointestinal peptide

    Grant number:24593103  2012.04 - 2015.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    YAGI Takakazu, MIYAWAKI Shouichi, INUI Akio, KAMIMURA Hiroki, UEDA Hirotaka

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    Grant amount:\5330000 ( Direct expense: \4100000 、 Indirect expense:\1230000 )

    This study focused on the relationship of stress and the stomatognathic function. As peripheral stimulation, we performed the acid stimulation to upper part gastrointestinal tract and, as central stimulation, we used corticotropin release factor where related stress. Recording procedure was mainly electromyogram (EMG: masseter muscle activity), electroencephalogram (EEG), and electrocardiogram (ECG). The result is that EMG increased after peripheral and central stimulation in comparison with before stimulation. In addition, quality of the sleep decreased, and it was suggested that the stimulation influenced the autonomic nervous system. On the other hand, in the gene expression of the stimulation on the upper gastrointestinal tract, ASIC3 and TRPV1 gained expression. It was suggested that peripheral stimulation was transmitted through the sense of pain related tract.
    Therefore, stress has close to the relations with the stomatognathic dysfunction.

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  • The association between stmatognathic function and the sensation of the stomach and esophagus via brain activity

    Grant number:24390464  2012.04 - 2015.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

    MIYAWAKI Shouichi, OHMURE Haruhito, YAGI Takakazu, UEDA Hirotaka, NAGAYAMA Kunihiro, MAEDA Aya, UEHARA Sawako, TSUBOUCHI Hirohito, IDO Akio, SAKIYAMA Toshio

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    Grant amount:\18200000 ( Direct expense: \14000000 、 Indirect expense:\4200000 )

    In the present study, we hypothesized that there is a strong correlation between stmatognathic function and the motility function of the stomach and esophagus. (1) Initial gastric emptying is suppressed by mastication, and that the suppression is caused by mastication-induced inhibition of gastric activity. (2) Esophageal-derived autonomic nervous system modulation induces masseter muscle activity, irrespective of the presence of subjective gastrointestinal symptoms. (3) By administering proton pump inhibitor to the patients with sleep bruxism, masseter muscle activity during sleep significantly decreased. (4) Involuntary teeth clenching is related to regional brain activity in the insula and anterior cingulate cortex. These studies suggest that the function and sensation of the stomach and esophagus may be closely related with a stmatognathic function via brain activity.

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  • コミュニケーションツールが青少年の睡眠、消化器疾患および顎発育に及ぼす影響の解明

    Grant number:24600015  2012.04 - 2013.03

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    坂口 勝義, 八木 孝和, 植田 紘貴, 吉田 礼子, 永山 邦宏, 宮脇 正一

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    Grant amount:\5460000 ( Direct expense: \4200000 、 Indirect expense:\1260000 )

    本年度は、小中学生を対象に、以下の調査。解析を行った。概要は次の通り。研究背景:小・中学生における問題行動が学校および社会における大きな問題と言われている。一方、小・中学生の睡眠に関する様々な問題も、学校生活や日常生活に影響を及ぼすとされ、問題視されてきている。睡眠障害を引き起こす原因のひとつに睡眠時の微小覚醒を生じさせる胃食道逆流症(GERD)があると言われている。本研究では、問題行動に関し、睡眠の動態とGERDの症状がどのように関連しているのかを検討するため、小・中学生を対象に問題行動と睡眠動態およびGERD症状を調査・解析したので報告する。対象は鹿児島県内在住の小・中学校の生徒30名(男子16名、女子14名、年齢10歳‐15歳)とその保護者である。方法:生徒の基本的属性と生活および睡眠に関する質問項目について、記入式で回答を得た。問題行動についてはPediatric Symptoms Checklist(PSC、日本語版)を用いて、GERD症状についてはFrequency Scale for the Symptoms of GERD(FSSG)を用いて回答を得た。睡眠動態についてはActiwatch2(米国フィリップスレシプロニクス社)を用いて、一夜の睡眠時間、入眠潜時、REM睡眠時間、non-REM睡眠時間、REM睡眠時間/睡眠時間、中途覚醒を記録し、解析した。PSCを基準に問題行動群と正常行動群に分け、生活および睡眠に関する事項、GERD症状ならびに睡眠動態を比較した。
    結果:小・中学生では、全体の15%に問題行動が見られた。問題行動を呈する者では食事習慣と睡眠に特徴がみられ、GERD症状が多く、睡眠に関して睡眠中の動態に乱れが見られた。問題行動とGERD症状、睡眠の乱れには関連があることが示唆された。以上の解析結果を英文にまとめ、現在、国際誌に投稿中である。

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  • Relationships among pediatric sleep problems, problem behavior, gastroesophageal reflux and oral parafunctions

    Grant number:21610016  2009 - 2011

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    SAKAGUCHI Katsuyoshi, MIYAWAKI Shouichi, OHMURE Haruhito, NAGAYAMA Kunihiro, UEDA Hirotaka, YAGI Takakazu

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    Grant amount:\4680000 ( Direct expense: \3600000 、 Indirect expense:\1080000 )

    We ivestigated the sleep disturbances, problem behavior, and symptoms of the gastroesophageal reflux of primary school children and junior high school children(total : 6087, boys : 3017, girls : 3070, age : 6-15 years old). In the problem behavior group, the symptoms of GERD and sleep disturbances were significantly more observed. Also, skipping breakfast, taking supper with part of their family, and shorter conversation at or after the supper and bruxism and clenching during sleep were significantly more observed than in the normal behavior group. It was suggested that the problem behavior has associations with dietary habit, sleep bruxism and clenching, and GERD symptoms.

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  • Influences of the occlusion on gastroesophageal reflux disease and acid clearance in oral cavity, pharynx and esophagus during sleep

    Grant number:20390524  2008 - 2011

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

    MIYAWAKI Shouichi, OHMURE Haruhito, SAKAGUCHI Katsuyoshi, TSUBOUCHI Hirohito, UEDA Hirotaka, NAGAYAMA Kunihiro

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    Grant amount:\18980000 ( Direct expense: \14600000 、 Indirect expense:\4380000 )

    In the present study, we hypothesized that good occlusion increases the acid clearance in the oral cavity, pharynx and esophagus, leading to the prohibition of the gastroesophageal reflux disease(GERD).
    (1) The results of the investigation of masticatory functions in patients with skeletal Class III malocclusion suggested that GERD symptoms were observed more often than in normal subjects.
    (2) The results of the investigation of the effects of intra-esophageal infusions of 5-mL acidic solution(0.1 N HCl) or saline to the healthy adults suggested that sleep bruxism episodes were induced by esophageal acidification.
    (3) Bruxism patients(n=7) had high frequency of GERD with a mild esophagitis.
    These researches show good occlusion has associations with esophageal acidification, suppression of upper gastrointestinal disease.

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  • Electrophysiological and immunohistological study of the inhibitory inputs from the forebrain and brainstem to the superior salivatory nucleus in rats

    Grant number:19890133  2007 - 2008

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Young Scientists (Start-up)

    FUJII Akihito, MATSUSHIMA Ayumi, UEDA Hirotaka

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    Grant amount:\3085000 ( Direct expense: \2680000 、 Indirect expense:\405000 )

    唾液は脳幹(下位中枢)を介し反射性に分泌されるだけでなく、前脳(上位中枢)からの入力によっても制御されている。しかし、その制御機構は基礎および臨床研究においても、未だ具体的に明らかにされていない。本研究課題では、免疫組織学および電気生理学的手法を用い、唾液分泌に対する上位および下位中枢からの抑制性制御機構について調ベた。
    その結果、全ての上唾液核細胞は上位中枢から抑制性入力を受けていることが明らかとなった。このことから、唾液分泌は興奮性入力のみならず、上位中枢からの下行性抑制性入力によっても調節されていることが示唆された。

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  • Clinical training:Early orthodontic treatment (2024academic year) special  - その他

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  • Clinical training:Early orthodontic treatment (2022academic year) special  - その他

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  • Research Projects and Practicals: Orthodontics and Dentofacial Orthopedics I (2021academic year) special  - その他

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  • Clinical training:Early orthodontic treatment (2020academic year) special  - その他

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