Faculty Profiles - NAITOU Hiromichi

Papers - NAITOU Hiromichi

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Case of necrotizing fasciitis from streptococcus pyogenes (group A) treated successfully with negative-pressure wound therapy. Reviewed

Inaba M, Nozaki S, Fujiwara T, Hongou T, Uozumi M, Nakahara T, Akagi Y, Kojima T, Naito H, Nakao A.

Surgical Infections Case Reports. 1 142 - 145 2016.11

The Clinical Application of Hydrogen as a Medical Treatment Reviewed

Iida Atsuyoshi, Nosaka Nobuyuki, Yumoto Tetsuya, Knaup Emily, Naito Hiromichi, Nishiyama Chihiro, Yamakawa Yasuaki, Tsukahara Kohei, Terado Michihisa, Sato Keiji, Ugawa Toyomu, Nakao Atsunori

Acta Medica Okayama 70 ( 5 ) 331 - 337 2016.10

A successfully treated case of iliopsoas abscess affecting urinary tract infection caused by streptococcus sanguis. Reviewed

Takeuchi N, Emori K, Yoshitani M, Soneda J, Naito H, Yumoto T, Tsukahara K, Nakao A.

Surg Infect Case Rep. 1 ( 1 ) 123 - 125 2016.9

Intraperitoneally administered, hydrogen-rich physiologic solution protects against postoperative ileus and is associated with reduced nitric oxide production Reviewed

Ayana Okamoto, Keisuke Kohama, Michiko Aoyama-Ishikawa, Hayato Yamashita, Noritomo Fujisaki, Taihei Yamada, Tetsuya Yumoto, Nobuyuki Nosaka, Hiromichi Naito, Kohei Tsukahara, Atsuyoshi Iida, Keiji Sato, Joji Kotani, Atsunori Nakao

Surgery 160 ( 3 ) 623 - 631 2016.9

A successfully treated case of iliopsoas abscess affecting urinary tract infection caused by streptococcus sanguis. Reviewed

Takeuchi N, Emori K, Yoshitani M, Soneda J, Naito H, Yumoto T, Tsukahara K, Nakao A

Surgical Infections Case Reports. 1 41 - 43 2016.2

Soft tissue hematoma of the neck due to thyroid rupture with unusual mechanism Reviewed

Kohei Tsukahara, Keiji Sato, Tetsuya Yumoto, Atsuyoshi Iida, Nobuyuki Nosaka, Michihisa Terado, Hiromichi Naito, Yorihisa Orita, Tomoyuki Naito, Kentaro Miki, Mayu Sugihara, Satoko Nagao, Toyomu Ugawa, Atsunori Nakao

International Journal of Surgery Case Reports 26 217 - 220 2016

Effects of antibiotics administration on the incidence of wound infection in percutaneous dilatational tracheostomy. Reviewed

Hideharu Hagiya, Hiromichi Naito, Shingo Hagioka, Shuji Okahara, Naoki Morimoto, Nobuchika Kusano, Fumio Otsuka

Acta medica Okayama 68 ( 2 ) 57 - 62 2014.8

Language：English Publishing type：Research paper (scientific journal)

The effect of antibiotics during the perioperative period of percutaneous dilatational tracheostomy (PDT) is still controversial. A total of 297 patients who underwent the PDT procedure were divided into 2 groups:those administered antibiotics perioperatively and those not administered antibiotics. Wound infections were noted in 7 cases (incidence rate, 2.36%) and no death was recorded. Of the 69 patients without antibiotics, 5 developed wound infections (incidence rate, 7.25%), while only 2 of the 228 patients with antibiotics developed wound infections (incidence rate, 0.88%) (p＝0.002;risk ratio, 8.82;95% confidence interval, 1.67-46.6). Of the 7 cases of wound infection, 5 cases occurred during the early period after PDT (within 7 days). Collectively, the present results suggest that prophylactic administration of antibiotics may prevent the incidence of PDT-induced wound infection, especially in the early phase after the PDT procedures. The need for antibiotics in PDT should be reconsidered.

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Acute methemoglobinemia caused by suicidal ingestion of liquid fertilizer Reviewed

Yasutoshi Kuroe, Hiromichi Naito, Junichi Sugiyama, Susumu Kawanishi, Naoki Morimoto, Shingo Hagioka

Clinical Toxicology 52 ( 7 ) 819 - 819 2014.8

Comprehensive analysis of systemically disseminated ST8/non-USA300 type community-acquired methicillin-resistant Staphylococcus aureus infection. Reviewed

Hideharu Hagiya, Junzo Hisatsune, Taro Kojima, Sumiko Shiota, Hiromichi Naito, Shingo Hagioka, Naoki Morimoto, Fumio Otsuka, Motoyuki Sugai

Internal medicine (Tokyo, Japan) 53 ( 8 ) 907 - 912 2014.3

Language：English Publishing type：Research paper (scientific journal)

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is genetically heterogeneous and various genotypes are spreading worldwide. We herein report a case of systematically disseminated Japan-intrinsic CA-MRSA infection that was successfully treated. A genetically identical single strain was isolated from a total of 11 different parts of the patient's body, and the pathogen was found to be multilocus sequence type 8, staphylococcal cassette chromosome mec IV, coagulase type III and negative for both Panton-Valentine leukocidin and arginine catabolic mobile element. The epidemiology and pathogenicity of the Japan-intrinsic CA-MRSA strain remain unknown, and further investigation of this life-threatening organism is warranted.

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Comprehensive Analysis of Systemically Disseminated ST8/non-USA300 type Community-acquired Methicillin-resistant Staphylococcus aureus Infection

Hideharu Hagiya, Junzo Hisatsune, Taro Kojima, Sumiko Shiota, Hiromichi Naito, Shingo Hagioka, Naoki Morimoto, Fumio Otsuka, Motoyuki Sugai

Internal Medicine 53 ( 8 ) 907 - 912 2014

Language：English Publishing type：Research paper (scientific journal) Publisher：Japanese Society of Internal Medicine

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is genetically heterogeneous and various genotypes are spreading worldwide. We herein report a case of systematically disseminated Japan-intrinsic CA-MRSA infection that was successfully treated. A genetically identical single strain was isolated from a total of 11 different parts of the patient's body, and the pathogen was found to be multilocus sequence type 8, staphylococcal cassette chromosome mec IV, coagulase type III and negative for both Panton-Valentine leukocidin and arginine catabolic mobile element. The epidemiology and pathogenicity of the Japan-intrinsic CA-MRSA strain remain unknown, and further investigation of this life-threatening organism is warranted.<br>

DOI： 10.2169/internalmedicine.53.1746

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重症呼吸不全に対するAirway Pressure Release Ventilationの肺酸素化能および循環動態に与える影響の検討. Reviewed

岡原修司, 内藤宏道, 萩岡信吾, 森本直樹, 森松博史, 森田潔.

ICUとCCU 37 219 - 223 2013.12

Quantitative Evaluation of the Neuroprotective Effects of a Short-acting β-Adrenoceptor Antagonist at a Clinical Dose on Forebrain Ischemia in Gerbils Reviewed

Tetsuya Danura, Yoshimasa Takeda, Kensuke Shiraishi, Hiromichi Naito, Ryoichi Mizoue, Sachiko Sato, Kiyoshi Morita

Journal of Neurosurgical Anesthesiology 25 ( 3 ) 292 - 298 2013.7

Effect of lidocaine on dynamic changes in cortical reduced nicotinamide adenine dinucleotide fluorescence during transient focal cerebral ischemia in rats Reviewed

H. Naito, Y. Takeda, T. Danura, I.S. Kass, K. Morita

Neuroscience 235 59 - 69 2013.4

In Reply: International journal

Yoshimasa Takeda, Hiroshi Hashimoto, Koji Fumoto, Tetsuya Danura, Hiromichi Naito, Naoki Morimoto, Hiroshi Katayama, Soichiro Fushimi, Akihiro Matsukawa, Aiji Ohtsuka, Kiyoshi Morita

Anesthesiology 118 ( 2 ) 469 - 470 2013.2

Emphysematous liver abscesses complicated by septic pulmonary emboli in patients with diabetes: two cases. Reviewed

Hideharu Hagiya, Yasutoshi Kuroe, Hiroyoshi Nojima, Shinkichi Otani, Junichi Sugiyama, Hiromichi Naito, Susumu Kawanishi, Shingo Hagioka, Naoki Morimoto

Internal medicine (Tokyo, Japan) 52 ( 1 ) 141 - 145 2013.2

Language：English Publishing type：Research paper (scientific journal)

An emphysematous liver abscess is a fatal condition that often occurs in patients with uncontrolled diabetes mellitus. I herein describe two cases of Klebsiella pneumoniae-induced emphysematous liver abscesses complicated by septic pulmonary emboli in patients with poorly controlled diabetes mellitus. Both patients showed hemoglobin A1c levels of more than 10% and did not present with any abdominal symptoms on admission. However, they were diagnosed and successfully treated with percutaneous transhepatic abscess drainage and antibiotics. This fatal disease should be taken into consideration in patients with uncontrolled diabetes mellitus who suffer from prolonged fevers and uncharacteristic general malaise.

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A fatal case of streptococcal toxic shock syndrome due to Streptococcus dysgalactiae subsp. equisimilis possibly caused by an intramuscular injection. Reviewed

Hideharu Hagiya, Shunji Okita, Yasutoshi Kuroe, Hiroyoshi Nojima, Shinkichi Otani, Junichi Sugiyama, Hiromichi Naito, Susumu Kawanishi, Shingo Hagioka, Naoki Morimoto

Internal medicine (Tokyo, Japan) 52 ( 3 ) 397 - 402 2013.2

Language：English Publishing type：Research paper (scientific journal)

An 88-year-old man died of streptococcal toxic shock syndrome due to a group G streptococcus infection that was possibly caused by an intramuscular injection given 30 hours earlier in his right deltoid muscle. The causative pathogen was later identified to be Streptococcus dysgalactiae subsp. equisimilis (stG485). Although providing intramuscular injections is an essential skill of health care workers that is performed daily worldwide, it may constitute a port of entry for pathogens via skin breaches that can cause life-threatening infections. All invasive procedures should be carefully performed, especially when immunologically compromised patients are involved.

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Co-infection with invasive pulmonary aspergillosis and Pneumocystis jirovecii pneumonia after corticosteroid therapy Reviewed International journal

Hideharu Hagiya, Yasutoshi Kuroe, Hiroyoshi Nojima, Junichi Sugiyama, Hiromichi Naito, Shingo Hagioka, Naoki Morimoto, Takayoshi Miyake, Yusuke Kokumai, Tomoko Murase

Journal of Infection and Chemotherapy 19 ( 2 ) 342 - 347 2013

Language：English Publishing type：Research paper (scientific journal) Publisher：Elsevier BV

A 95-year-old man with chronic obstructive pulmonary disease and chronic hepatitis C virus infection was treated for acute lung injury caused by Chlamydophila pneumoniae with antibiotics and high-dose corticosteroids. In total, 7,500 mg methylprednisolone and 680 mg prednisolone were administered over 21 days. However, respiratory failure progressed, and chest computed tomography (CT) scan showed bilateral ground-glass opacity and cavity-forming consolidation in the right upper lobe. Despite intensive therapy, the patient died of multiple organ failure on day 7. CT-guided necropsy was performed, and pathological examination revealed invasive pulmonary aspergillosis and Pneumocystis jirovecii pneumonia. Invasive pulmonary aspergillosis and P. jirovecii pneumonia are both life-threatening opportunistic fungal infections. Co-infection of these organisms is rare but possible if the patient is in an extremely immunocompromised state. Short-term but high-dose systemic corticosteroid therapy was considered to be the risk factor in this case. We should pay more attention to immunocompromised hosts who might be suffering from co-infection of opportunistic infections. Moreover, we need to consider preventive measures in such high-risk cases.

DOI： 10.1007/s10156-012-0473-9

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Delftia acidovorans bacteremia caused by bacterial translocation after organophosphorus poisoning in an immunocompetent adult patient Reviewed International journal

Hideharu Hagiya, Junichi Sugiyama, Yasutoshi Kuroe, Hiroyoshi Nojima, Hiromichi Naito, Shingo Hagioka, Naoki Morimoto, Tomoko Murase

Journal of Infection and Chemotherapy 19 ( 2 ) 338 - 341 2013

Language：English Publishing type：Research paper (scientific journal) Publisher：Elsevier BV

A 46-year-old woman was transferred to our emergency unit because of impaired consciousness and respiratory failure with the history of excessive pesticide intake. The patient was hypersalivative and had bilateral pupillary miosis. Laboratory results showed markedly decreased cholinesterase. She was intubated and treated in the intensive care unit with the diagnosis of organophosphorus poisoning. The patient had persisted diarrhea, with a high fever and stomach tenderness on day 10. Whole-body contrast enhanced computed tomography revealed a swollen, enhanced small intestinal wall, and blood culture identified Delftia acidovorans. She was diagnosed as D. acidovorans bacteremia, probably caused by bacterial translocation based on the clinical presentation and the exclusion of other sources, and treated well with a total of 8 days of antibiotic therapy. So far as we know, this is the first case of D. acidovorans bacteremia that was presumably caused by bacterial translocation after organophosphorus poisoning in an immunocompetent adult patient.

DOI： 10.1007/s10156-012-0472-x

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A Fatal Case of Streptococcal Toxic Shock Syndrome due to Streptococcus dysgalactiae subsp. equisimilis Possibly Caused by an Intramuscular Injection

Hideharu Hagiya, Shunji Okita, Yasutoshi Kuroe, Hiroyoshi Nojima, Shinkichi Otani, Junichi Sugiyama, Hiromichi Naito, Susumu Kawanishi, Shingo Hagioka, Naoki Morimoto

Internal Medicine 52 ( 3 ) 397 - 402 2013

Language：English Publishing type：Research paper (scientific journal) Publisher：Japanese Society of Internal Medicine

An 88-year-old man died of streptococcal toxic shock syndrome due to a group G streptococcus infection that was possibly caused by an intramuscular injection given 30 hours earlier in his right deltoid muscle. The causative pathogen was later identified to be Streptococcus dysgalactiae subsp. equisimilis (stG485). Although providing intramuscular injections is an essential skill of health care workers that is performed daily worldwide, it may constitute a port of entry for pathogens via skin breaches that can cause life-threatening infections. All invasive procedures should be carefully performed, especially when immunologically compromised patients are involved.<br>

DOI： 10.2169/internalmedicine.52.8846

CiNii Article

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Emphysematous Liver Abscesses Complicated by Septic Pulmonary Emboli in Patients with Diabetes: Two Cases

Hideharu Hagiya, Yasutoshi Kuroe, Hiroyoshi Nojima, Shinkichi Otani, Junichi Sugiyama, Hiromichi Naito, Susumu Kawanishi, Shingo Hagioka, Naoki Morimoto

Internal Medicine 52 ( 1 ) 141 - 145 2013

Language：English Publishing type：Research paper (scientific journal) Publisher：Japanese Society of Internal Medicine

An emphysematous liver abscess is a fatal condition that often occurs in patients with uncontrolled diabetes mellitus. I herein describe two cases of Klebsiella pneumoniae-induced emphysematous liver abscesses complicated by septic pulmonary emboli in patients with poorly controlled diabetes mellitus. Both patients showed hemoglobin A1c levels of more than 10% and did not present with any abdominal symptoms on admission. However, they were diagnosed and successfully treated with percutaneous transhepatic abscess drainage and antibiotics. This fatal disease should be taken into consideration in patients with uncontrolled diabetes mellitus who suffer from prolonged fevers and uncharacteristic general malaise.<br>

DOI： 10.2169/internalmedicine.52.8737

CiNii Article

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