研究者詳細 - 内藤　宏道

論文 - 内藤　宏道

分割表示 193 件中 181 - 193 件目／全件表示 >>

Effects of pharyngeal cooling on brain temperature in primates and humans 査読

Takeda Y, Hashimoto H, Fumoto K, Danura T, Naito H, Morimoto N, Katayama H, Fushimi S, Matukawa A, Ohtsuka A, Morita K.

Anesthesiology 117 2012年12月

Necrotizing duodenitis caused by Clostridium perfringens type A in a Japanese young man. 査読

Hagiya H, Naito H, Sugiyama J, Nojima H, Hagioka S, Morimoto N.

Intern Med. 51 ( 20 ) 2973 - 2976 2012年10月

Severe soft tissue Infection of the lower extremity caused by Haemophilus influenzae (serotype f, biotype II) in an adult patient. 査読

Hagiya H, Murase T, Naito H, Hagioka S, Morimoto N.

Intern Med. 51 ( 13 ) 1783 - 1787 2012年10月

Effects of Pharyngeal Cooling on Brain Temperature in Primates and Humans 査読国際誌

Yoshimasa Takeda, Hiroshi Hashimoto, Koji Fumoto, Tetsuya Danura, Hiromichi Naito, Naoki Morimoto, Hiroshi Katayama, Soichiro Fushimi, Akihiro Matsukawa, Aiji Ohtsuka, Kiyoshi Morita

Anesthesiology 117 ( 1 ) 117 - 125 2012年7月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Ovid Technologies (Wolters Kluwer Health)

<sec>
<title>Background</title>
Pharyngeal cooling decreases brain temperature by cooling carotid arteries. This study was designed to evaluate the principle of pharyngeal cooling in monkeys and humans.

</sec>
<sec>
<title>Methods</title>
Monkeys (n = 10) were resuscitated following 12 min of cardiac arrest. Pharyngeal cooling (n = 5), in which cold saline (5°C) was perfused into the cuff at the rate of 500 ml/min, was initiated simultaneously with the onset of resuscitation for 30 min. Patients (n = 3) who were in an intensive care unit were subjected to 30 min of pharyngeal cooling under propofol anesthesia.

</sec>
<sec>
<title>Results</title>
In the animal study, core brain temperature was significantly decreased compared with that in the control group by 1.9°C (SD = 0.8, P &lt; 0.001) and 3.1°C (SD = 1.0, P &lt; 0.001) at 10 min and 30 min after the onset of cooling, respectively. The cooling effect was more evident in an animal with low postresuscitation blood pressure. Total dose of epinephrine, number of direct current shocks, and recovery of blood pressure were not different between the two groups. The pharyngeal epithelium was microscopically intact on day 5. In the clinical study, insertion of the cuff and start of perfusion did not affect heart rate or blood pressure. Tympanic temperature was decreased by 0.6 ± 0.1°C/30 min without affecting bladder temperature. The pharynx was macroscopically intact for 3 days.

</sec>
<sec>
<title>Conclusions</title>
Pharyngeal cooling rapidly and selectively decreased brain temperature in primates and tympanic temperature in humans and did not have adverse effects on return of spontaneous circulation, even when initiated during cardiac arrest in primates.

</sec>

DOI： 10.1097/aln.0b013e3182580536

PubMed

researchmap

その他リンク： https://journals.lww.com/10.1097/ALN.0b013e3182580536

ALI/ARDSに対するNPPV成功の予測因子の検討. 査読

岡原修司, 内藤宏道, 萩岡信吾, 萩谷英大, 杉山淳一, 勝田知也, 森本直樹.

日本救急医学会雑誌 23 768 - 774 2012年6月

急性上腸間膜動脈閉塞症における予後に関わる因子の検討査読

西田傑, 萩岡信吾, 内藤宏道, 杉山雅俊, 森本直樹.

日本集中治療医学会雑誌 19 ( 1 ) 33 - 37 2012年1月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：The Japanese Society of Intensive Care Medicine

【目的】急性上腸間膜動脈閉塞症の予後に関わる因子を検討する。【方法】当院で経験した急性上腸間膜動脈閉塞症症例27例を28日生存群と死亡群に分け，患者背景，血液検査所見，所要時間を予後に関わる可能性のある因子として抽出した。【結果】死亡群では，Acute Physiology and Chronic Health Evaluation II（APACHE II）スコア18.2±6.4，乳酸値8.1±4.3 mmol/l，クレアチニン2.3±1.1 mg/dlが生存群に対して有意に高値だった。症状発現から治療開始までの時間は死亡群，生存群ともに15時間で変わらなかった。【結論】症状発現から治療開始までの時間は予後とは関わっておらず，クレアチニン，乳酸値が予後の指標として使用できる可能性が考えられた。

DOI： 10.3918/jsicm.19.33

CiNii Article

CiNii Books

researchmap

その他リンク： http://search.jamas.or.jp/link/ui/2012121452

Severe Soft Tissue Infection of the Lower Extremity Caused by Haemophilus influenzae (serotype f, biotype II) in an Adult Patient 査読

Hagiya Hideharu, Murase Tomoko, Naito Hiromichi, Hagioka Shingo, Morimoto Naoki

Internal Medicine 51 ( 13 ) 1783 - 1787 2012年

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：The Japanese Society of Internal Medicine

The infection caused by non-b-type Haemophilus influenzae has been increasing in this Hib (H.influenzae serotype b) vaccination era. H.influenzae serotype f (Hif) is considered as one of those emerging pathogens. In general, H.influenzae is a common pathogen of such as pneumonia, otitis media, and meningitis, but is rare in soft tissue infection, especially at the extremity. We report a rare case of severe soft tissue infection caused by Hif which occurred at the lower extremity of immunocompetent adult patient.<br>

DOI： 10.2169/internalmedicine.51.7209

CiNii Article

researchmap

Necrotizing Duodenitis Caused by Clostridium perfringens Type A in a Japanese Young Man

Hagiya Hideharu, Naito Hiromichi, Sugiyama Junichi, Nojima Hiroyoshi, Hagioka Shingo, Morimoto Naoki

Internal Medicine 51 ( 20 ) 2973 - 2976 2012年

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：The Japanese Society of Internal Medicine

A 21-year-old Japanese man with a history of marked body weight loss over a short period of time died of necrotizing duodenitis caused by Clostridium perfringens (C. perfringens) type A. C. perfringens type A is considered to usually cause self-limiting gastroenteritis. Necrotizing enteritis sometimes occurs due to C. perfringens in developing countries; however, it is primarily caused by the type C strain and its site of onset is typically the jejunum or ileum. This is a rare case of necrotizing duodenitis caused by C. perfringens type A in a Japanese young man. Physicians need to be more aware of this emerging fatal disease in developed countries.<br>

DOI： 10.2169/internalmedicine.51.8407

CiNii Article

researchmap

症例報告除草剤(ラッソー乳剤)服用後,長期間にわたり痙攣が持続した1例

内藤宏道, 長江正晴, 岡原修司

中毒研究 24 ( 1 ) 35 - 38 2011年