MISC - 杉生　憲志

外科学の根幹は手術である─すべては「患者さんのために」─（スペシャルインタビュー）

松本健五, 杉生憲志

脳神経外科速報   26 ( 6 )   552 - 563   2016年

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岡山大学におけるHybrid ORでの手術.

菱川朋人, 杉生憲志, 安原隆雄, 伊達 勲

脳卒中の外科   44 ( 2 )   125 - 131   2016年

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DOI： 10.2335/scs.44.125

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頚動脈ステント留置術後の急性期ステント内血栓症に対してステント留置術を追加した2例

西廣真吾, 杉生憲志, 菱川朋人, 平松匡文, 春間純, 高杉祐二, 新治有径, 木谷尚哉, 高橋悠, 伊達勲

脳血管内治療(Web)   1 ( Supplement )   2016年

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J-GLOBAL

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高齢者頚動脈狭窄症に対するstaged angioplastyの有効性

菱川朋人, 西廣真吾, 高橋悠, 木谷尚哉, 新治有径, 高杉祐二, 春間純, 平松匡文, 杉生憲志, 伊達勲

脳血管内治療(Web)   1 ( Supplement )   2016年

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J-GLOBAL

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「過灌流症候群高リスク例に対する頚動脈ステント留置術に関する後ろ向き研究」最終結果報告

早川幹人, 菱川朋人, 杉生憲志, 早川幹人, 菱川朋人, 杉生憲志, 山上宏, 坂井信幸, 飯原弘二, 小笠原邦昭, 大石英則, 伊藤靖, 松丸祐司, 吉村紳一, 松丸祐司, 吉村紳一

脳血管内治療(Web)   1 ( Supplement )   2016年

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J-GLOBAL

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HPへのstaged CASは有効か? 日本からの発信 「過灌流症候群高リスク例に対する頸動脈ステント留置術に関する後ろ向き研究」結果報告

菱川 朋人, 杉生 憲志, 三橋 利晴, 早川 幹人, 山上 宏, 坂井 信幸, 飯原 弘二, 小笠原 邦昭, 大石 英則, 伊藤 靖, 松丸 祐司, 吉村 紳一, STOP CHS研究班

JNET: Journal of Neuroendovascular Therapy   9 ( 6 )   S200 - S200   2015年11月

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記述言語：日本語   出版者・発行元：(NPO)日本脳神経血管内治療学会  

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Combined Transarterial and Transvenous Approach for Curative Obliteration of Klippel-Trenaunay-Weber Syndrome-Associated Spinal Perimedullary Arteriovenous Fistulas

K. Tokunaga, T. Hishikawa, K. Sugiu, I. Date

CLINICAL NEURORADIOLOGY   25 ( 3 )   291 - 294   2015年9月

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記述言語：英語   出版者・発行元：SPRINGER HEIDELBERG  

DOI： 10.1007/s00062-014-0319-1

Web of Science

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静脈うっ滞により急速に脳幹症状を呈した頚髄硬膜動静脈瘻の1例

佐々木達也, 眞鍋博明, 安原隆雄, 三好康之, 杉生憲志, 伊達 勲

脳神経外科   43 ( 1 )   51 - 56   2015年

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NeuroIVR 5年後のカテ

杉生憲志

Rad Fan   13 ( 12 )   74 - 75   2015年

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私の手術論no. 77─脳血管内治療の「文武両道」─

杉生憲志, 吉村紳一

脳神経外科速報   25 ( 11 )   1128 - 1138   2015年

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摘出術前の腫瘍栄養血管塞栓術が有用であった馬尾血管芽腫の1例

馬越通有, 安原隆雄, 三好康之, 平松匡文, 豊嶋敦彦, 佐々田晋, 守本 純, 菱川朋人, 眞鍋博明, 徳永浩司, 杉生憲志, 伊達 勲

脊髄外科   29 ( 1 )   53 - 58   2015年

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記述言語：日本語   出版者・発行元：The Japanese Society of Spinal Surgery  

Spinal hemangioblastomas are benign, and total surgical resection is the standard treatment method used. However, hypervascular tumors may have excessive operative blood loss if the tumors are divided. We encountered a case of cauda equina hemangioblastoma with extraordinary blood supply, which was treated with preoperative embolization. A 49-year-old woman with von Hippel-Lindau disease who had undergone multiple surgeries for intracranial/extracranial hemangioblastomas had lumbago and leg pain. Magnetic resonance images revealed intradural spinal tumors at the L4-S1 vertebral level, with remarkable gadolinium enhancement. The patient was referred to our hospital, after a plan of total resection had been abandoned elsewhere because of the high flow feeders and high pressure of the tumors. Preoperative embolization was performed with consequent disappearance of the arterial blood supply to the tumor. Two days later, the tumor was resected subtotally with reduced tension and a little blood loss. The patient's symptoms resolved soon after surgery. Selective preoperative embolization for a spinal hemangioblastoma with a rich blood supply is a valid option as an adjuvant to the complete surgical resection of a tumor.

DOI： 10.2531/spinalsurg.29.53

CiNii Article

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その他リンク： http://search.jamas.or.jp/link/ui/2015281939

もやもや病の病態解析

菱川朋人, 平松匡文, 徳永浩司, 杉生憲志, 伊達 勲

脳神経外科ジャーナル   24 ( 4 )   239 - 243   2015年

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記述言語：中国語  

DOI： 10.7887/jcns.24.239

Scopus

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Long-term outcomes in adult patients with ischemic-type moyamoya disease involving posterior circulation 国際誌

Tomohito Hishikawa, Koji Tokunaga, Kenji Sugiu, Isao Date

ACTA NEUROCHIRURGICA   156 ( 9 )   1745 - 1751   2014年9月

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記述言語：英語   出版者・発行元：SPRINGER WIEN  

The object of this study was to compare the long-term outcomes in adult patients with moyamoya disease (MMD) with posterior circulation involvement (PCi) treated through surgical revascularization with those in adult patients without PCi.
The records of 32 consecutive adult patients with ischemic-type MMD who were treated with revascularization were reviewed. Twelve of these patients (38 %) had PCi at initial onset. Clinical characteristics of the patients with PCi were compared to those without PCi. Neurological outcomes were assessed using the modified Rankin Scale (mRS) in the preoperative and postoperative follow-up periods. A five-year Kaplan-Meier stroke risk was calculated.
The frequency of presenting with infarction was significantly higher among patients with PCi than among those without PCi (p = 0.006). mRS scores in the preoperative period were significantly higher in patients with PCi than in patients without PCi (p = 0.0004). There were no significant differences in mRS scores between the preoperative and postoperative follow-up period in patients with PCi (p = 0.3), nor were there any between the preoperative and postoperative follow-up periods in patients without PCi (p = 0.2). The five-year Kaplan-Meier risk of surgical morbidity and ipsilateral stroke was 14.3 % in surgically treated hemispheres with PCi versus 14.9 % in surgically treated hemispheres without PCi (p = 0.96).
PCi at initial onset was significantly correlated with poor outcome. Revascularization for the middle cerebral artery territory in patients with PCi was effective at preventing recurrent ischemic stroke.

DOI： 10.1007/s00701-014-2136-3

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PubMed

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Long-term outcomes in adult patients with ischemic-type moyamoya disease involving posterior circulation

Tomohito Hishikawa, Koji Tokunaga, Kenji Sugiu, Isao Date

ACTA NEUROCHIRURGICA   156 ( 9 )   1745 - 1751   2014年9月

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記述言語：英語   出版者・発行元：SPRINGER WIEN  

The object of this study was to compare the long-term outcomes in adult patients with moyamoya disease (MMD) with posterior circulation involvement (PCi) treated through surgical revascularization with those in adult patients without PCi.
The records of 32 consecutive adult patients with ischemic-type MMD who were treated with revascularization were reviewed. Twelve of these patients (38 %) had PCi at initial onset. Clinical characteristics of the patients with PCi were compared to those without PCi. Neurological outcomes were assessed using the modified Rankin Scale (mRS) in the preoperative and postoperative follow-up periods. A five-year Kaplan-Meier stroke risk was calculated.
The frequency of presenting with infarction was significantly higher among patients with PCi than among those without PCi (p = 0.006). mRS scores in the preoperative period were significantly higher in patients with PCi than in patients without PCi (p = 0.0004). There were no significant differences in mRS scores between the preoperative and postoperative follow-up period in patients with PCi (p = 0.3), nor were there any between the preoperative and postoperative follow-up periods in patients without PCi (p = 0.2). The five-year Kaplan-Meier risk of surgical morbidity and ipsilateral stroke was 14.3 % in surgically treated hemispheres with PCi versus 14.9 % in surgically treated hemispheres without PCi (p = 0.96).
PCi at initial onset was significantly correlated with poor outcome. Revascularization for the middle cerebral artery territory in patients with PCi was effective at preventing recurrent ischemic stroke.

DOI： 10.1007/s00701-014-2136-3

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Nationwide survey of the nature and risk factors of complications in embolization of meningiomas and other intracranial tumors: Japanese Registry of NeuroEndovascular Therapy 2 (JR-NET2) 国際誌

Tomohito Hishikawa, Kenji Sugiu, Masafumi Hiramatsu, Jun Haruma, Koji Tokunaga, Isao Date, Nobuyuki Sakai

NEURORADIOLOGY   56 ( 2 )   139 - 144   2014年2月

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記述言語：英語   出版者・発行元：SPRINGER  

Embolization of intracranial tumor is widely performed in Japan, mainly before neurosurgical resection. A retrospective, multicenter, observational study in Japan was conducted to clarify the nature, frequency, and risk factors of complications in intracranial tumor embolization.
Patients were derived from the Japanese Registry of NeuroEndovascular Therapy 2 (JR-NET2). A total of 20,854 patients were enrolled in JR-NET2, of which 1,018 patients (4.88 %) with intracranial tumors underwent embolization. The primary end point was the proportion of patients with a modified Rankin scale (mRS) score of 0-2 (independency) at 30 days. The secondary end point was the occurrence of complications related to the procedures. The risk factors of the occurrence of complications were studied.
The proportion of patients with mRS scores a parts per thousand currency sign2 at 30 days after procedure was 91.3 %. Complications occurred in 15 of the 1,012 patients (1.48 %). Multivariate analysis showed that embolization for tumors other than meningioma (OR, 4.626; 95 % CI, 1.347-14.59; p = 0.0105) was significantly associated with the development of complications.
The frequency of complications after intracranial tumor embolization was relatively low in this large Japanese cohort. Embolization for tumors other than meningioma was the only significant risk factor for the occurrence of complications.

DOI： 10.1007/s00234-013-1300-4

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PubMed

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Nationwide survey of the nature and risk factors of complications in embolization of meningiomas and other intracranial tumors: Japanese Registry of NeuroEndovascular Therapy 2 (JR-NET2)

Tomohito Hishikawa, Kenji Sugiu, Masafumi Hiramatsu, Jun Haruma, Koji Tokunaga, Isao Date, Nobuyuki Sakai

NEURORADIOLOGY   56 ( 2 )   139 - 144   2014年2月

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記述言語：英語   出版者・発行元：SPRINGER  

Embolization of intracranial tumor is widely performed in Japan, mainly before neurosurgical resection. A retrospective, multicenter, observational study in Japan was conducted to clarify the nature, frequency, and risk factors of complications in intracranial tumor embolization.
Patients were derived from the Japanese Registry of NeuroEndovascular Therapy 2 (JR-NET2). A total of 20,854 patients were enrolled in JR-NET2, of which 1,018 patients (4.88 %) with intracranial tumors underwent embolization. The primary end point was the proportion of patients with a modified Rankin scale (mRS) score of 0-2 (independency) at 30 days. The secondary end point was the occurrence of complications related to the procedures. The risk factors of the occurrence of complications were studied.
The proportion of patients with mRS scores a parts per thousand currency sign2 at 30 days after procedure was 91.3 %. Complications occurred in 15 of the 1,012 patients (1.48 %). Multivariate analysis showed that embolization for tumors other than meningioma (OR, 4.626; 95 % CI, 1.347-14.59; p = 0.0105) was significantly associated with the development of complications.
The frequency of complications after intracranial tumor embolization was relatively low in this large Japanese cohort. Embolization for tumors other than meningioma was the only significant risk factor for the occurrence of complications.

DOI： 10.1007/s00234-013-1300-4

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Recent Trends in Neuroendovascular Therapy in Japan: Analysis of a Nationwide Survey-Japanese Registry of Neuroendovascular Therapy (JR-NET) 1 and 2

Nobuyuki Sakai, Shinichi Yoshimura, Waro Taki, Akio Hyodo, Shigeru Miyachi, Yoji Nagai, Chiaki Sakai, Tetsu Satow, Tomoaki Terada, Masayuki Ezura, Toshio Hyogo, Shunji Matsubara, Kentaro Hayashi, Toshiyuki Fujinaka, Yasushi Ito, Shigeki Kobayashi, Masaki Komiyama, Naoya Kuwayama, Yuji Matsumaru, Yasushi Matsumoto, Yuichi Murayama, Ichiro Nakahara, Shigeru Nemoto, Koichi Satoh, Kenji Sugiu, Akira Ishii, Hirotoshi Imamura

NEUROLOGIA MEDICO-CHIRURGICA   54 ( 1 )   1 - 8   2014年1月

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記述言語：英語   出版者・発行元：JAPAN NEUROSURGICAL SOC  

The present study retrospectively analyzed the database of the Japanese Registry of Neuroendovascular Therapy 1 and 2 (JR-NET1&2) to determine annual trends, including adverse events and clinical outcomes at 30 days after undergoing neuroendovascular therapy. JR-NET1&2 are surveys that targeted all patients in Japan who underwent neuroendovascular therapy delivered by physicians certified by the Japanese Society of Neuroendovascular Therapy (JSNET) between 2005 and 2009. Medical information about the patients was anonymized and retrospectively registered via a website. Data from 32,608 patients were analyzed. The number of treated patients constantly increased from 5,040 in 2005 to 7,406 in 2009 and the rate of octogenarians increased from 7.0% in 2005 to 10.4% in 2009. The proportion of procedures remained relatively constant, but ratios of angioplasty slightly increased from 32.8% in 2005 to 33.7% in 2009. Procedural complications were associated more frequently with acute stroke (9.6%), ruptured aneurysms (7.4%), intracranial artery disease (ICAD) (5.4%), and arteriovenous malformation (AVM, 5.2%). The number of patients requiring neuroendovascular treatment in Japan is increasing and the outcomes of such therapy are clinically acceptable. Details of each type of treatment will be investigated in sub-analyses of the database.

DOI： 10.2176/nmc.oa.2013-0197

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PubMed

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Recent trends in neuroendovascular therapy in Japan: Analysis of a nationwide survey ─Japanese Registry of Neuroendovascular Therapy (JR-NET) 1 and 2─

Sakai N, Yoshimura S, Taki W, Hyodo A, Miyachi S Nagai Y, Sakai C, Satow T, Terada T, Ezura M, Hyogo T, Matsubara S, Hayashi K, Fujinaka T, Ito Y, Kobayashi S, Komiyama M, Kuwayama N, Matsumaru Y, Matsumoto Y, Murayama Y, Nakahara I, Nemoto S, Satoh K, Sugiu K, Ishii A, Imamura H, JR-NET Investigators

Neurologia medico-chirurgica   54 ( 1 )   1 - 8   2014年1月

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記述言語：英語  

DOI： 10.2176/nmc.oa.2013-0197

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岡山大学における症候性脳血管攣縮への対策と現状─過去10年間の治療成績の検討─

菱川朋人, 清水智久, 徳永浩司, 杉生憲志, 小野成紀, 伊達 勲

脳血管攣縮 Vol.29   41 ( Suppl )   23 - 26   2014年

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記述言語：日本語   出版者・発行元：スパズム・シンポジウム事務局  

過去10年間に外科治療を行った脳動脈瘤破裂によるクモ膜下出血88例(男40例、女48例、平均65.4歳)の成績を報告した。治療方法はclip 42例、coil 46例で、2007年以前(前期)の52例ではclip 34例、coil 18例、2008年以降(後期)の36例ではそれぞれ8例、28例とcoilが有意に増加していた。治療直前のHunt and Kosnik gradeは前期と後期で有意差はなく、clipとcoilの比較では前期がcoilで有意にgradeが高かったが、後期は有意差がなかった。症候性血管攣縮は25例に認め、前期35%、後期19%で有意差はなかった。退院時modified Rankin Scaleで0〜2の予後良好は前期32.7%、後期33.3%、3〜6の予後不良例のうち症候性血管攣縮が主な予後規定因子となったのはそれぞれ20%、16.7%と有意差はなかった。

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コイル塞栓術─治療編─

杉生憲志

BRAIN NURSING   30 ( 4 )   387 - 389   2014年

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