研究者詳細 - 杉生　憲志

論文 - 杉生　憲志

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脳血行再建と次世代型治療過灌流症候群高リスクの頸動脈ステント留置術施行例における術前SPECT所見の検討 STOP CHS後ろ向き研究

早川幹人, 梶本勝文, 杉生憲志, 菱川朋人, 山上宏, 坂井信幸, 飯原弘二, 小笠原邦昭, 大石英則, 伊藤靖, 松丸祐司, 吉村紳一

脳循環代謝 28 ( 1 ) 106 - 106 2016年11月

右総頸動脈に収縮期に逆行性血流を呈した腕頭動脈閉塞の1例査読

武本梨佳, 戸田洋伸, 戸田由香, 勢井麻梨, 中村知子, 渡辺修久, 江尻健太郎, 麻植浩樹, 杉生憲志, 岡田健, 大塚文男, 伊藤浩

超音波検査技術 41 ( Suppl. ) S230 - S230 2016年6月

ラットくも膜下出血後脳血管攣縮に対する抗HMGB-1抗体の攣縮抑制効果造影CTと血中HMGB-1濃度

春間純, 菱川朋人, 劉克約, 西廣真吾, 新治有径, 高杉佑二, 平松匡文, 杉生憲志, 西堀正洋, 伊達勲

脳血管攣縮 31 64 - 64 2016年2月

Single injectionによるラットくも膜下出血モデルの急性期におけるspreading depressionの可視化

高杉祐二, 菱川朋人, 清水智久, 西廣真吾, 新治有径, 春間純, 平松匡文, 杉生憲志, 伊達勲

脳血管攣縮 31 55 - 55 2016年2月

Clinical Analysis of Fever, Headache, and Gastrointestinal Symptoms after Endosaccular Coil Embolization in Patients with Unruptured Cerebral Aneurysms— A Study of "Post Coiling Syndrome"

Okuma Yu, Sugiu Kenji, Tokunaga Koji, Nishida Ayumi, Hishikawa Tomohito, Itami Hisakazu, Hiramatsu Masafumi, Date Isao

Journal of Neuroendovascular Therapy 2016年

記述言語：英語出版者・発行元：特定非営利活動法人日本脳神経血管内治療学会

Objective: Unidentified fever, headache, and gastrointestinal symptoms after endosaccular coil embolization are occasionally observed in patients with unruptured cerebral aneurysms. We defined these symptoms as post coiling syndrome (PCS) and analyzed the clinical risk factors involved.Methods: We applied the PCS diagnostic criteria based on the scoring of symptoms, which include fever, headache, nausea, and/or vomiting. Thirty-six consecutive patients were included in this retrospective study. Systematic follow-up included clinical and blood examinations.Results: Based on our criteria, 11 of 36 patients were diagnosed with PCS. Between patients in the PCS group and patients in the non-PCS group, we recognized significant differences in age (63.4 ± 12.5 vs. 53.8 ± 12.9, respectively; p <0.029) as patient background and in aneurysmal diameter (9.96 ± 4.24 vs. 6.48 ± 3.06, respectively; p <0.049), aneurysmal volume (242 ± 254 vs. 87.9 ± 70.1, respectively; p <0.015), total coil length (122 ± 106 vs. 39.1 ± 25.7, respectively; p <0.0021), and volume embolization ratio as aneurysmal data (41.9 ± 8.1 vs. 30.7 ± 8.5, respectively; p <0.0019). In addition, we recognized a significant difference in postoperative leukocytosis as an inflammatory factor.Conclusions: Patient age, aneurysmal diameter, aneurysmal volume, total coil length, and volume embolization may enable the prediction of PCS.

DOI： 10.5797/jnet.oa.2016-0036

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Stent-assisted coil embolization of a dissecting aneurysm of the posterior cerebral artery: A case report 査読

Jun Haruma, Kenji Sugiu, Tadato Yukiue, Tatsuya Sasaki, Yasuhiko Hattori, Kazuki Kobayashi, Hideyuki Yoshida, Koji Muneda, Isao Date

Neurological Surgery 43 ( 12 ) 1099 - 1104 2015年12月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Igaku-Shoin Ltd

Dissecting aneurysms of the posterior cerebral artery (PCA) are rare, especially those at the P1 segment. Here, we describe the case of a 57-year-old woman with a subarachnoid hemorrhage (SAH). Computed tomography angiography (CTA) and digital subtraction angiography (DSA) revealed a small (3 mm) dissecting aneurysm with the typical peari-and-string sign at the right P1 segment. Fourteen days after onset, the patient developed aphasia. DSA revealed vasospasm of the right middle cerebral artery, and we performed endovascular treatment by the intra-arterial injection of 1-(5-isoquinolinesulfonyl) homopiperazine. After this treatment, the patient's symptoms recovered immediately. Vertebral angiography revealed enlargement of the dissecting aneurysm (up to 7 mm diameter). We started a loading dose of 300 mg aspirin and 400 mg Clopidogrel after observing growth of the aneurysm. Fifteen days after onset, we performed a stent-assisted coil embolization, and obtained nearly complete obliteration of the aneurysm with preserved patency of the parent artery. Six-month follow-up DSA demonstrated complete occlusion of the aneurysm with good patency of the stented PCA: the patient was at modified Rankin Scale 1. In the treatment of ruptured dissecting aneurysms, parent vessel occlusion (PVO) with aneurysm is common. However. PVO may cause both cerebral infarction of the distal area and perforator occlusion of the occluded vessel. Stent-assisted coil embolization can preserve parent vessel flow and obliterate the aneurysm. Stents offer a therapeutic alternative for PCA dissecting aneurysms, especially when PVO cannot be tolerated.

DOI： 10.11477/mf.1436203187

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未破裂脳動脈瘤コイル塞栓術後に多発性の大脳病変を呈した一例

出口健太郎, 出口章子, 河原由子, 佐藤恒太, 武本麻美, 菱川望, 太田康之, 山下徹, 徳永浩司, 杉生憲志, 河井信行, 阿部康二

JNET: Journal of Neuroendovascular Therapy 9 ( 6 ) S358 - S358 2015年11月