Faculty Profiles - YASUI Kazuya

Papers - YASUI Kazuya

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肝静脈狭窄によるOut-flow Block、十二指腸憩室穿孔による度重なる腹腔内出血と大量腹水に苦悩した生体肝移植の1例

安井和也, 佐藤真歩, 谷口厚樹, 木村次郎, 木村裕司, 高木弘誠, 藤智和, 楳田祐三, 藤原俊義

移植 58 ( 総会臨時 ) 265 - 265 2023.9

ゲノム医療の最前線循環遊離DNAメチル化パターンは原発腫瘍変異プロファイルなしに大腸癌検出とモニタリングを可能とする

永坂岳司, 戸嶋俊明, 稲田凉, 安井和也, 楳田祐三, 岡脇誠, 入谷光洋, 矢野修也, 谷岡洋亮, 山田岳史, 猶本良夫

日本大腸肛門病学会雑誌 76 ( 9 ) A67 - A67 2023.9

膵・胆管合流異常に対する術後晩期合併症の検討

木村次郎, 藤智和, 廣野欣司, 佐藤真歩, 萱野真史, 山田元彦, 木村裕司, 高木弘誠, 安井和也, 楳田祐三, 藤原俊義

日本膵・胆管合流異常研究会プロシーディングス 46 43 - 43 2023.9

Robotic Pancreaticoduodenectomy Using the Right Posterior Superior Mesenteric Artery Approach. Reviewed International journal

Kosei Takagi, Yuzo Umeda, Tomokazu Fuji, Kazuya Yasui, Toshiyoshi Fujiwara

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 27 ( 12 ) 3069 - 3070 2023.8

肝移植後患者に発症したメトロニダゾール誘発性脳症の1例 Reviewed

實金悠, 安井和也, 楳田祐三, 八木孝仁, 藤原俊義

日本臨床外科学会雑誌 84 ( 8 ) 1301 - 1307 2023.8

Language：Japanese Publisher：日本臨床外科学会

患者は57歳,男性.Budd-Chiari症候群による非代償性肝硬変に対して46歳時に生体肝移植術後.慢性期に門脈狭窄に起因する門脈圧亢進症に伴う腸炎や肝性脳症を繰り返していたが,肝不全兆候はなく外来フォロー中であった.今回,間質性肺炎急性増悪に対しステロイド加療中にClostridium difficile腸炎を併発,メトロニダゾール内服にて軽快したが,腸炎症状は遷延していたためメトロニダゾール1g/日の内服を継続していた.約2ヵ月後に内服服薬管理困難,構音障害,手指振戦が出現し,症状発現から1週間後に意識障害の増悪を認め受診.頭部MRIで両側対称性に小脳歯状核の高信号域を確認,メトロニダゾール誘発性脳症と診断した.速やかにメトロニダゾールを中止したことで,徐々に意識レベルは改善した.メトロニダゾール誘発性脳症の発症は稀であり,肝移植・肝障害に関連した報告例は少なく,過去の文献的考察を加えて報告する.(著者抄録)

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Other Link： https://search.jamas.or.jp/default/link?pub_year=2023&ichushi_jid=J03156&link_issn=&doc_id=20230907150026&doc_link_id=10.3919%2Fjjsa.84.1301&url=https%3A%2F%2Fdoi.org%2F10.3919%2Fjjsa.84.1301&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_3.gif

Innovative suture technique for robotic hepaticojejunostomy: double-layer interrupted sutures. Reviewed International journal

Kosei Takagi, Yuzo Umeda, Ryuichi Yoshida, Tomokazu Fuji, Kazuya Yasui, Takahito Yagi, Toshiyoshi Fujiwara

Langenbeck's archives of surgery 408 ( 1 ) 284 - 284 2023.7

Language：English Publishing type：Research paper (scientific journal)

PURPOSE: Biliary reconstruction remains a technically demanding and complicated procedure in minimally invasive hepatopancreatobiliary surgeries. No optimal hepaticojejunostomy (HJ) technique has been demonstrated to be superior for preventing biliary complications. This study aimed to investigate the feasibility of our unique technique of posterior double-layer interrupted sutures in robotic HJ. METHODS: We performed a retrospective analysis of a prospectively collected database. Forty-two patients who underwent robotic pancreatoduodenectomy using this technique between September 2020 and November 2022 at our center were reviewed. In the posterior double-layer interrupted technique, sutures were placed to bite the bile duct, posterior seromuscular layer of the jejunum, and full thickness of the jejunum. RESULTS: The median operative time was 410 (interquartile range [IQR], 388-478) min, and the median HJ time was 30 (IQR, 28-39) min. The median bile duct diameter was 7 (IQR, 6-10) mm. Of the 42 patients, one patient (2.4%) had grade B bile leakage. During the median follow-up of 12.6 months, one patient (2.4%) with bile leakage developed anastomotic stenosis. Perioperative mortality was not observed. A surgical video showing the posterior double-layer interrupted sutures in the robotic HJ is included. CONCLUSIONS: Posterior double-layer interrupted sutures in robotic HJ provided a simple and feasible method for biliary reconstruction with a low risk of biliary complications.

DOI： 10.1007/s00423-023-03020-1

PubMed

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非大腸癌由来の少数肝転移症例の切除適応を見極める

岡田尚大, 藤智和, 楳田祐三, 吉田龍一, 高木弘誠, 安井和也, 黒田新士, 野間和広, 寺石文則, 藤原俊義

日本消化器外科学会総会 78回 O11 - 6 2023.7

【肝胆膵】膵頭十二指腸切除術後膵液瘻の克服を目指した工夫膵頭十二指腸切除術のハイリスク膵空腸吻合におけるロボット支援下手術の役割

藤智和, 高木弘誠, 楳田祐三, 吉田龍一, 安井和也, 黒田新士, 野間和広, 寺石文則, 藤原俊儀

日本消化器外科学会総会 78回 WS32 - 7 2023.7

【肝胆膵】切除可能膵癌に対する術前化学療法の至適戦略血中循環腫瘍DNA内KRAS mutation profileとCA19-9値を組み合わせた膵癌予後の層別化戦略

安井和也, 吉田龍一, 宮本耕吉, 藤智和, 高木弘誠, 寺石文則, 黒田新士, 野間和広, 楳田祐三, 藤原俊義

日本消化器外科学会総会 78回 WS30 - 10 2023.7

【肝胆膵】切除可能膵癌に対する術前化学療法の至適戦略血中循環腫瘍DNA内KRAS mutation profileとCA19-9値を組み合わせた膵癌予後の層別化戦略

安井和也, 吉田龍一, 宮本耕吉, 藤智和, 高木弘誠, 寺石文則, 黒田新士, 野間和広, 楳田祐三, 藤原俊義

日本消化器外科学会総会 78回 WS30 - 10 2023.7

【肝胆膵】膵頭十二指腸切除術後膵液瘻の克服を目指した工夫膵頭十二指腸切除術のハイリスク膵空腸吻合におけるロボット支援下手術の役割

藤智和, 高木弘誠, 楳田祐三, 吉田龍一, 安井和也, 黒田新士, 野間和広, 寺石文則, 藤原俊儀

日本消化器外科学会総会 78回 WS32 - 7 2023.7

非大腸癌由来の少数肝転移症例の切除適応を見極める

岡田尚大, 藤智和, 楳田祐三, 吉田龍一, 高木弘誠, 安井和也, 黒田新士, 野間和広, 寺石文則, 藤原俊義

日本消化器外科学会総会 78回 O11 - 6 2023.7

膵頭部癌術前CT画像診断精度の実際病理診断からの振り返り

谷口厚樹, 安井和也, 藤原俊義

日本消化器外科学会総会 78回 S20 - 2 2023.7

膵癌診療における検体固定の工夫と外科医と病理医間での相互フィードバックの実際

安井和也, 木村次郎, 高木弘誠, 藤智和, 楳田祐三, 藤原俊義

膵臓 38 ( 3 ) A461 - A461 2023.7

低侵襲時代の膵臓手術ロボット支援下膵切除術の定型化と普及にむけて

高木弘誠, 楳田祐三, 吉田龍一, 藤智和, 安井和也, 木村次郎, 八木孝仁, 藤原俊義

膵臓 38 ( 3 ) A179 - A179 2023.7

【必携ロボット支援下消化器外科手術-基本手技とトラブルシューティング】肝胆膵領域ロボット支援下先天性胆道拡張症手術

高木弘誠, 楳田祐三, 藤智和, 安井和也, 藤原俊義, 八木孝仁

手術 77 ( 8 ) 1231 - 1238 2023.7

外科専攻医の産育休後復帰支援とダイバーシティ推進のための全体教育への取り組み

竹原裕子, 溝尾妙子, 小林純子, 安井和也, 菊池覚次, 黒田新士, 楳田祐三, 吉田龍一, 小谷恭弘, 杉本誠一郎, 岡崎幹生, 枝國忠彦, 豊岡伸一, 笠原真悟

日本外科学会定期学術集会抄録集 123回 SF - 4 2023.4

ロボット支援下肝胆膵高難度手術の導入と教育システムの確立

高木弘誠, 吉田龍一, 藤智和, 安井和也, 八木孝仁, 藤原俊義

日本外科学会定期学術集会抄録集 123回 SF - 3 2023.4

Impact of educational video on performance in robotic simulation training (TAKUMI-1): a randomized controlled trial. Reviewed International journal

Kosei Takagi, Nanako Hata, Jiro Kimura, Satoru Kikuchi, Kazuhiro Noma, Kazuya Yasui, Tomokazu Fuji, Ryuichi Yoshida, Yuzo Umeda, Takahito Yagi, Toshiyoshi Fujiwara

Journal of robotic surgery 17 ( 4 ) 1547 - 1553 2023.3

Language：English Publishing type：Research paper (scientific journal)

The use of virtual reality for simulations plays an important role in the initial training for robotic surgery. This randomized controlled trial aimed to investigate the impact of educational video on the performance of robotic simulation. Participants were randomized into the intervention (video) group that received an educational video and robotic simulation training or the control group that received only simulation training. The da Vinci® Skills Simulator was used for the basic course, including nine drills. The primary endpoint was the overall score of nine drills in cycles 1-10. Secondary endpoints included overall, efficiency, and penalty scores in each cycle, as well as the learning curves evaluated by the cumulative sum (CUSUM) analysis. Between September 2021 and May 2022, 20 participants were assigned to the video (n = 10) and control (n = 10) groups. The video group had significantly higher overall scores than the control group (90.8 vs. 72.4, P < 0.001). Significantly higher overall scores and lower penalty scores were confirmed, mainly in cycles 1-5. CUSUM analysis revealed a shorter learning curve in the video group. The present study demonstrated that educational video training can be effective in improving the performance of robotic simulation training and shortening the learning curve.

DOI： 10.1007/s11701-023-01556-4

PubMed

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Role of the Pfannenstiel Incision in Robotic Hepato-Pancreato-Biliary Surgery. Reviewed International journal

Kosei Takagi, Yuzo Umeda, Ryuichi Yoshida, Tomokazu Fuji, Kazuya Yasui, Jiro Kimura, Nanako Hata, Takahito Yagi, Toshiyoshi Fujiwara

Journal of clinical medicine 12 ( 5 ) 2023.3

Language：English Publishing type：Research paper (scientific journal)

Studies remain limited on the role of the Pfannenstiel incision in minimally invasive hepato-pancreato-biliary (HPB) surgery, especially robotic surgery. The role of various extraction sites in robotic HPB surgery should be understood. Herein, we describe the surgical techniques, outcomes, advantages, and disadvantages of the Pfannenstiel incision in robotic pancreatic surgery. Seventy patients underwent robotic pancreatectomy at our institution between September 2020 and October 2022. The Pfannenstiel incision was used for specimen retrieval in 55 patients. Advantages of the Pfannenstiel incision include less pain, cosmetic benefits, and a lower incidence of complications. Moreover, the specimen could be removed using the robotic system docked. However, all complex reconstructions should be performed intra-abdominally during robotic pancreatoduodenectomies. The incidence of mortality and postoperative pancreatic fistula (grade B) was 0% and 9.1%, respectively. During the median follow-up (11.2 months) after surgery, complications at the Pfannenstiel incision site included surgical site infection (n = 1, 1.8%) and incisional hernia (n = 1, 1.8%). The Pfannenstiel incision can be a useful option for specimen retrieval in minimally invasive HPB surgery, according to the surgeon's preferences and the patient's condition.

DOI： 10.3390/jcm12051971

PubMed

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Papers - YASUI Kazuya