研究者詳細 - 井澤　俊

論文 - 井澤　俊

分割表示 >> ／全件表示 68 件中 1 - 68 件目

Comprehensive clinical evaluation of indirect and direct bonding techniques in orthodontic treatment: a single-centre, open-label, quasi-randomized controlled clinical trial 査読

Kana Kono, Takashi Murakami, Saori Tanizaki, Noriaki Kawanabe, Atsuro Fujisawa, Masahiro Nakamura, Mitsuhiro Hoshijima, Takashi Izawa, Hiroshi Kamioka

European Journal of Orthodontics 46 ( 6 ) cjae036 2024年12月

Clinical Prediction Models for Upper Airway Volume Based on Soft Palate and Airway Lumen Dimensions in Adults With Varying Vertical Skeletal Patterns

Janvier Habumugisha, Sumire Ida, Masahiro Nakamura, Kana Kono, Kenta Uchida, Takumi Moriya, Megumi Konko, Satoru Hayano, Takashi Izawa, Hiroshi Kamioka

International Dental Journal 2024年10月

Novel prediction models for pharyngeal-airway volume based on the cranial-base and midsagittal cross-sectional area of the airway in the pharyngeal region: a cephalometric and magnetic resonance imaging study. 査読

Habumugisha J, Nakamura M, Kono K, Uchida K, Konko M, Izawa T, Kamioka H

Orthodontics and Craniofacial Research 27 ( 3 ) 394 - 402 2024年6月

NSAIDs系鎮痛薬の常用による歯の移動の遅延を認めた上下顎前突症例の一治験例

中西泰之, 植田紘貴, 星島光博, 井澤俊, 上岡寛

日本矯正歯科学会大会プログラム・抄録集 81回 229 - 229 2022年10月

HIF‐1α controls palatal wound healing by regulating macrophage motility via S1P/S1P ₁ signaling axis 査読

Islamy Rahma Hutami, Takashi Izawa, Tsendsuren Khurel‐Ochir, Takuma Sakamaki, Akihiko Iwasa, Shuhei Tomita, Eiji Tanaka

Oral Diseases 28 ( 4 ) 1157 - 1169 2022年5月

ThPOK inhibits osteoclast formation via NFATc1 transcription and function 査読国際共著国際誌

Wei Zou, Takashi Izawa, Nidhi Rohatgi, Steven Y Zou, Yongjia Li, Steven L Teitelbaum

JBMR Plus 6 ( 4 ) e10613 2022年3月

低出力超音波パルス照射は機械的負荷に起因して生じた下顎頭軟骨変性を修復する

坂巻拓馬, 岩浅亮彦, Xia Linze, 井澤俊, 加納史也, 山本朗仁, 田中栄二

日本顎関節学会雑誌 33 ( Suppl. ) 80 - 80 2021年10月

O‐GlcNAcylation drives calcium signaling toward osteoblast differentiation: A bioinformatics‐oriented study 査読国際誌

Yao Weng, Ziyi Wang, Yoko Fukuhara, Airi Tanai, Mika Ikegame, Daisuke Yamada, Takeshi Takarada, Takashi Izawa, Satoru Hayano, Kaya Yoshida, Hiroshi Kamioka, Hirohiko Okamura

BioFactors 47 ( 6 ) 992 - 1015 2021年8月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Wiley

This study aimed to reveal the possible mechanisms by which O-linked-N-acetylglucosaminylation (O-GlcNAcylation) regulates osteoblast differentiation using a series of bioinformatics-oriented experiments. To examine the influence of O-GlcNAcylation levels on osteoblast differentiation, osteoblastic MC3T3-E1 cells were treated with O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA) inhibitors. Correlations between the levels of O-GlcNAcylation and the expression of osteogenic markers as well as OGT were evaluated by qPCR and western blotting. The O-GlcNAcylated proteins assumed to correlate with Runx2 expression were retrieved from several public databases and used for further bioinformatics analysis. Following the findings of the bioinformatics analysis, intracellular calcium ([Ca2+ ]i ) was monitored in the cells treated with OGT and OGA inhibitors using a confocal laser-scanning microscope (CLS). The interaction effect between O-GlcNAcylation and [Ca2+ ]i on osteogenic marker expression was determined using stable OGT knockdown MC3T3-E1 cells. O-GlcNAcylation was positively associated with osteoblast differentiation. The time-course profile of global O-GlcNAcylated proteins showed a distinctive pattern with different molecular weights during osteoblast differentiation. The expression pattern of several O-GlcNAcylated proteins was significantly similar to that of Runx2 expression. Bioinformatic analysis of the retrieved Runx2-related-O-GlcNAcylated-proteins revealed the importance of [Ca2+ ]i . CLS showed that alteration of O-GlcNAcylation rapidly changed [Ca2+ ]i in MC3T3-E1 cells. O-GlcNAcylation and [Ca2+ ]i showed an interaction effect on the expression of osteogenic markers. OGT knockdown disrupted the [Ca2+ ]i -induced expression changes of osteogenic markers. O-GlcNAcylation interacts with [Ca2+ ]i and elicits osteoblast differentiation by regulating the expression of osteogenic markers.

DOI： 10.1002/biof.1774

PubMed

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その他リンク： https://onlinelibrary.wiley.com/doi/full-xml/10.1002/biof.1774

Macrophage Motility in Wound Healing Is Regulated by HIF-1α via S1P Signaling 査読

Islamy Hutami, Takashi Izawa, Tsendsuren Khurel-Ochir, Takuma Sakamaki, Akihiko Iwasa, Eiji Tanaka

International Journal of Molecular Sciences 22 ( 16 ) 8992 - 8992 2021年8月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：MDPI AG

Accumulating evidence indicates that the molecular pathways mediating wound healing induce cell migration and localization of cytokines to sites of injury. Macrophages are immune cells that sense and actively respond to disturbances in tissue homeostasis by initiating, and subsequently resolving, inflammation. Hypoxic conditions generated at a wound site also strongly recruit macrophages and affect their function. Hypoxia inducible factor (HIF)-1α is a transcription factor that contributes to both glycolysis and the induction of inflammatory genes, while also being critical for macrophage activation. For the latter, HIF-1a regulates sphingosine 1-phosphate (S1P) to affect the migration, activation, differentiation, and polarization of macrophages. Recently, S1P and HIF-1α have received much attention, and various studies have been performed to investigate their roles in initiating and resolving inflammation via macrophages. It is hypothesized that the HIF-1α/S1P/S1P receptor axis is an important determinant of macrophage function under inflammatory conditions and during disease pathogenesis. Therefore, in this review, biological regulation of monocytes/macrophages in response to circulating HIF-1α is summarized, including signaling by S1P/S1P receptors, which have essential roles in wound healing.

DOI： 10.3390/ijms22168992

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Roles for B[a]P and FICZ in subchondral bone metabolism and experimental temporomandibular joint osteoarthritis via the AhR/Cyp1a1 signaling axis 査読

Yuri Yoshikawa, Takashi Izawa, Yusaku Hamada, Hiroko Takenaga, Ziyi Wang, Naozumi Ishimaru, Hiroshi Kamioka

Scientific Reports 11 ( 1 ) 14927 2021年7月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Springer Science and Business Media LLC

<title>Abstract</title>Bone loss due to smoking represents a major risk factor for fractures and bone osteoporosis. Signaling through the aryl hydrocarbon receptor (AhR) and its ligands contributes to both bone homeostasis and inflammatory diseases. It remains unclear whether the same AhR signaling axis affects the temporomandibular joint (TMJ). The aim of this study was to investigate possible mechanisms which mediate bone loss in the TMJ due to smoking. In particular, whether benzo[<italic>a</italic>]pyrene (B[<italic>a</italic>]P), a carcinogen of tobacco smoke, induces expression of the AhR target gene, Cyp1a1, in mandibular condyles. Possible functions of an endogenous ligand of FICZ, were also investigated in a TMJ-osteoarthritis (OA) mouse model. B[<italic>a</italic>]P was administered orally to wild-type and <italic>AhR</italic>^−/− mice and bone metabolism was subsequently examined. TMJ-OA was induced in wild-type mice with forceful opening of the mouth. Therapeutic functions of FICZ were detected with μCT and histology. Exposure to B[<italic>a</italic>]P accelerated bone loss in the mandibular subchondral bone. This bone loss manifested with osteoclastic bone resorption and upregulated expression of Cyp1a1 in an <italic>AhR</italic>-dependent manner. In a mouse model of TMJ-OA, FICZ exhibited a dose-dependent rescue of mandibular subchondral bone loss by repressing osteoclast activity. Meanwhile, in vitro, pre-treatment with FICZ reduced RANKL-mediated osteoclastogenesis. B[<italic>a</italic>]P regulates mandibular subchondral bone metabolism via the Cyp1a1. The AhR ligand, FICZ, can prevent TMJ-OA by regulating osteoclast differentiation.

DOI： 10.1038/s41598-021-94470-4

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その他リンク： http://www.nature.com/articles/s41598-021-94470-4

The immunoregulatory role of p21 in the development of the temporomandibular joint‐osteoarthritis 査読

Tsendsuren Khurel‐Ochir, Takashi Izawa, Akihiko Iwasa, Fumiya Kano, Akihito Yamamoto, Eiji Tanaka

Clinical and Experimental Dental Research 7 ( 3 ) 313 - 322 2021年6月

下垂体機能低下を伴う中隔視神経異形成症患者の矯正歯科治療症例査読

河野加奈, 柳田剛志, 井澤俊, 上岡寛

岡山歯学会雑誌 40 ( 1 ) 1 - 10 2021年6月

Loading history changes the morphology and compressive force-induced expression of receptor activator of nuclear factor kappa B ligand/osteoprotegerin in MLO-Y4 osteocytes 査読国際誌

Ziyi Wang, Yao Weng, Yoshihito Ishihara, Naoya Odagaki, Ei Ei Hsu Hlaing, Takashi Izawa, Hirohiko Okamura, Hiroshi Kamioka

PeerJ 8 e10244 - e10244 2020年11月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：PeerJ

<sec>
<title>Background</title>
In this study, we investigated the effect of the mechanical loading history on the expression of receptor activator of nuclear factor kappa B ligand (RANKL) and osteoprotegerin (OPG) in MLO-Y4 osteocyte-like cells.

</sec>
<sec>
<title>Methods</title>
Three hours after MLO-Y4 osteocytes were seeded, a continuous compressive force (CCF) of 31 dynes/cm² with or without additional CCF (32 dynes/cm²) was loaded onto the osteocytes. After 36 h, the additional CCF (loading history) was removed for a recovery period of 10 h. The expression of RANKL, OPG, RANKL/OPG ratio, cell numbers, viability and morphology were time-dependently examined at 0, 3, 6 and 10 h. Then, the same additional CCF was applied again for 1 h to all osteocytes with or without the gap junction inhibitor to examine the expression of RANKL, OPG, the RANKL/OPG ratio and other genes that essential to characterize the phenotype of MLO-Y4 cells. Fluorescence recovery after photobleaching technique was also applied to test the differences of gap-junctional intercellular communications (GJIC) among MLO-Y4 cells.

</sec>
<sec>
<title>Results</title>
The expression of RANKL and OPG by MLO-Y4 osteocytes without a loading history was dramatically decreased and increased, respectively, in response to the 1-h loading of additional weight. However, the expression of RANKL, OPG and the RANKL/OPG ratio were maintained at the same level as in the control group in the MLO-Y4 osteocytes with a loading history but without gap junction inhibitor treatment. Treatment of loading history significantly changed the capacity of GJIC and protein expression of connexin 43 (Cx43) but not the mRNA expression of Cx43. No significant difference was observed in the cell number or viability between the MLO-Y4 osteocyte-like cells with and without a loading history or among different time checkpoints during the recovery period. The cell morphology showed significant changes and was correlated with the expression of OPG, Gja1 and Dmp1 during the recovery period.

</sec>
<sec>
<title>Conclusion</title>
Our findings indicated that the compressive force-induced changes in the RANKL/OPG expression could be habituated within at least 11 h by 36-h CCF exposure. GJIC and cell morphology may play roles in response to loading history in MLO-Y4 osteocyte-like cells.

</sec>

DOI： 10.7717/peerj.10244

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その他リンク： https://peerj.com/articles/10244.xml

核内受容体AhRはRANK/c-Fosシグナル伝達経路を介して破骨細胞の分化を制御する

井澤俊, 吉川友理, 石丸直澄, 上岡寛

日本骨形態計測学会雑誌 30 ( 1 ) S97 - S97 2020年5月

Skeletal open bite with amelogenesis imperfecta treated with compression osteogenesis: a case report. 査読

Mori H, Izawa T, Mori H, Watanabe K, Kanno T, Tanaka E

Head Face Med 15 ( 1 ) 3 2019年1月

Crosstalk between Fas and S1P1 signaling via NF-kB in osteoclasts controls bone destruction in the TMJ due to rheumatoid arthritis 査読

Hutami IR, Tanaka E, Izawa T

Japanese Dental Science Review 55 ( 1 ) 12 - 19 2019年1月

矯正患者における永久歯の先天欠如に関する臨床統計調査査読

小笠原直子, 岩浅亮彦, 堀内信也, 井澤俊, 田中栄二

中・四国矯正歯科学会雑誌 30 ( 1 ) 59 - 64 2018年8月

Effectiveness of presurgical nasoalveolar molding therapy on unilateral cleft lip nasal deformity 査読

Nao Kinouchi, Shinya Horiuchi, Akihiro Yasue, Yuko Kuroda, Nobuhiko Kawai, Keiichiro Watanabe, Takashi Izawa, Ichiro Hashimoto, Ali H. Hassan, Eiji Tanaka

Saudi Medical Journal 39 ( 2 ) 169 - 178 2018年2月

Potential role of rebamipide in osteoclast differentiation and mandibular condylar cartilage homeostasis 査読

Takashi Izawa, Islamy Rahma Hutami, Eiji Tanaka

Current Rheumatology Reviews 14 ( 1 ) 62 - 69 2018年

Skeletal anchorage for intrusion of bimaxillary molars in a patient with skeletal open bite and temporomandibular disoeders. 査読

Iwasa A, Horiuchi S, Kinouchi N, Izawa T, Hiasa M, Kawai N, Yasue A, Hassan AH, Tanaka E

Journal of Orthodontic Science 6 ( 4 ) 152 - 158 2017年10月

Fas/S1P1 crosstalk via NF-κB activation in osteoclasts controls subchondral bone remodeling in murine TMJ arthritis 査読

Hutami IR, Izawa T, Mino-Oka A, Shinohara T, Mori H, Iwasa A, Tanaka E

Biochemical and Biophysical Research Communications 490 ( 4 ) 1274 - 1281 2017年9月

Role of Fas and RANKL signaling in peripheral immune tolerance 査読

Izawa T, Arakaki R, Ishimaru N

Journal of Clinical & Cellular Immunology 8 ( 4 ) 512 2017年7月

Role of Smad3 and S1P signal in mandibular condylar cartilage homeostasis 査読

Izawa T, Hutami IR, Mori H, Tanaka E

Journal of Bone Research 5 ( 2 ) 178 - 178 2017年7月

Crosstalk between cytokine RANKL and AhR signalling in osteoclasts controls bone homeostasis 査読

Izawa T, Arakaki R, Ishimaru N

Journal of Cytokine Biology 2 ( 2 ) 114 2017年5月

Long-term follow-up of a patient with achondroplasia treated with an orthodontic approach 査読

Hiroyo Mori, Kazuma Matsumoto, Nobuhiko Kawai, Takashi Izawa, Shinya Horiuchi, Eiji Tanaka

AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS 151 ( 4 ) 793 - 803 2017年4月

Roles of hypoxia inducible factor-1 alpha in the temporomandibular joint 査読

Akiko Mino-Oka, Takashi Izawa, Takehiro Shinohara, Hiroki Mori, Akihiro Yasue, Shuhei Tomita, Eiji Tanaka

ARCHIVES OF ORAL BIOLOGY 73 274 - 281 2017年1月

Hyaluronan metabolism in overloaded temporomandibular joint 査読

T. Shinohara, T. Izawa, A. Mino-Oka, H. Mori, A. Iwasa, T. Inubushi, Y. Yamaguchi, E. Tanaka

JOURNAL OF ORAL REHABILITATION 43 ( 12 ) 921 - 928 2016年12月

The Nuclear Receptor AhR Controls Bone Homeostasis by Regulating Osteoclast Differentiation via the RANK/c-Fos Signaling Axis 査読

Takashi Izawa, Rieko Arakaki, Hiroki Mori, Takaaki Tsunematsu, Yasusei Kudo, Eiji Tanaka, Naozumi Ishimaru

JOURNAL OF IMMUNOLOGY 197 ( 12 ) 4639 - 4650 2016年12月

H Amelotin gene expression is temporarily being upregulated at the initiation of apoptosis induced by TGF beta 1 in mouse gingival epithelial cells 査読

Yohei Nakayama, Sari Matsui, Keisuke Noda, Mizuho Yamazaki, Yasunobu Iwai, Hiroyoshi Matsumura, Takashi Izawa, Eiji Tanaka, Bernhard Ganss, Yorimasa Ogata

APOPTOSIS 21 ( 10 ) 1057 - 1070 2016年10月

Rebamipide Attenuates Mandibular Condylar Degeneration in a Murine Model of TMJ-OA by Mediating a Chondroprotective Effect and by Downregulating RANKL-Mediated Osteoclastogenesis (vol 11, e0154107, 2016) 査読

Takashi Izawa, Hiroki Mori, Takehiro Shinohara, Akiko Mino-Oka, Islamy Rahma Hutami, Akihiko Iwasa, Eiji Tanaka

PLOS ONE 11 ( 8 ) e0162032 2016年8月

Rebamipide Attenuates Mandibular Condylar Degeneration in a Murine Model of TMJ-OA by Mediating a Chondroprotective Effect and by Downregulating RANKL-Mediated Osteoclastogenesis 査読

Takashi Izawa, Hiroki Mori, Tekehiro Shinohara, Akiko Mino-Oka, Islamy Rahma Hutami, Akihiko Iwasa, Eiji Tanaka

PLOS ONE 11 ( 4 ) e0154107 2016年4月

Smad3 Deficiency Leads to Mandibular Condyle Degradation via the Sphingosine 1-Phosphate (S1P)/S1P(3) Signaling Axis 査読

Hiroki Mori, Takashi Izawa, Eiji Tanaka

AMERICAN JOURNAL OF PATHOLOGY 185 ( 10 ) 2742 - 2756 2015年10月

顎関節内障を有する骨格性下顎前突症に対する矯正歯科治療の一治験例査読

篠原丈裕, 渡邉佳一郎, 森浩喜, 井澤俊, 堀内信也

中・四国矯正歯科学会雑誌 27 ( 1 ) 39 - 48 2015年8月

ASXL2 Regulates Glucose, Lipid, and Skeletal Homeostasis 査読

Takashi Izawa, Nidhi Rohatgi, Tomohiro Fukunaga, Qun-Tian Wang, Matthew J. Silva, Michael J. Gardner, Michael L. McDaniel, Nada A. Abumrad, Clay F. Semenkovich, Steven L. Teitelbaum, Wei Zou

CELL REPORTS 11 ( 10 ) 1625 - 1637 2015年6月

ASXL2-director of skeletal and metabolic homeostasis. 査読

Research highlights by, David Holmes

Nature Reviews Endocrinology 11 ( 8 ) 445 2015年6月

Talin1 and Rap1 are Critical for Osteoclast Function. 査読

Zou W, Izawa T, Zhu T, Chappel J, Otero K, Monkley SJ, Critchley DR, Petrich BG, Morozov A, Ginsberg MH, Teitelbaum SL

Molecular and Cellular Biology 33 ( 4 ) 830 - 44 2013年2月

Fas-Independent T-Cell Apoptosis by Dendritic Cells Controls Autoimmune Arthritis in MRL/lpr Mice 査読

Takashi Izawa, Tomoyuki Kondo, Mie Kurosawa, Ritsuko Oura, Kazuma Matsumoto, Eiji Tanaka, Akiko Yamada, Rieko Arakaki, Yasusei Kudo, Yoshio Hayashi, Naozumi Ishimaru

PLOS ONE 7 ( 12 ) e48798 2012年12月

c-Src links a RANK/αvβ3 integrin complex to the osteoclast cytoskeleton. 査読

Izawa T, Zou W, Chappel JC, Ashley JW, Feng X, Teitelbaum SL

Molecular and Cellular Biology 32 ( 14 ) 2943 - 2953 2012年7月

関節リウマチ病態における破骨細胞を介したT細胞活性化機構の解析

松本一真, 石丸直澄, 井澤俊, 大浦律子, 岩浅亮彦, 林良夫, 田中栄二

日本顎関節学会雑誌 23 ( Suppl. ) 102 - 102 2011年7月

Oligodontiaを伴う著しい過蓋咬合に対する包括的治療例

松本一真, 井澤

中・四国矯正歯科学会雑誌 22 ( 1 ) 49 - 56 2010年8月

Biomechanical and biochemical characteristics of the mandibular condylar cartilage 査読

S. Kuroda, K. Tanimoto, T. Izawa, S. Fujihara, J. H. Koolstra, E. Tanaka

OSTEOARTHRITIS AND CARTILAGE 17 ( 11 ) 1408 - 1415 2009年11月

Analysis of gene expression profiles in human periodontal ligament cells under hypoxia: The protective effect of CC chemokine ligand 2 to oxygen shortage 査読

Yukiko Kitase, Masahiko Yokozeki, Shinji Fujihara, Takashi Izawa, Shingo Kuroda, Kotaro Tanimoto, Keiji Moriyama, Eiji Tanaka

ARCHIVES OF ORAL BIOLOGY 54 ( 7 ) 618 - 624 2009年7月

Regional differences in fiber characteristics in the rat temporalis muscle 査読

E. Tanaka, R. Sano, N. Kawai, J. A. M. Korfage, S. Nakamura, T. Izawa, G. E. J. Langenbach, K. Tanne

JOURNAL OF ANATOMY 213 ( 6 ) 743 - 748 2008年12月

下顎枝垂直骨切り術と下顎枝矢状分割術を併用した外科的矯正治療後に下顎頭のリモデリングを認めた一症例査読

井澤俊, 堀内信也, 辻けい子, 藤原慎視, 大庭康雄, 田中栄二, 森山啓司

日本顎関節学会雑誌 Vol.20 ( No.2 ) 134 - 138 2008年8月

エナメル質形成不全を伴う空隙歯列症例の一治験例査読

藤原慎視, 堀内信也, 井澤俊, 辻けい子, 大庭康雄, 森山啓司

中・四国矯正歯科学会雑誌 20 ( 1 ) 55 - 60 2008年8月

下顎枝垂直骨切り術と下顎枝矢状分割術を併用した外科的矯正治療後に下顎頭のリモデリングを認めた一症例査読

井澤俊, 堀内信也, 森山啓司

日本顎関節学会雑誌 20 ( 2 ) 134 - 138 2008年

RANKLシグナルを介した関節炎モデルマウス樹状細胞の機能解析査読

井澤俊, 林良夫, 森山啓司

日本矯正歯科学会大会プログラム・抄録集 66回 145 - 145 2007年9月

Immunoregulatory role of RANKL-stimulated dendritic cells on autoimmune arthritis in MRL/Ipr mice 査読

T. Izawa, N. Ishimaru, K. Moriyama, Y. Hayashi

JOURNAL OF BONE AND MINERAL RESEARCH 22 S270 - S270 2007年9月

Crosstalk between RANKL and Fas signaling in dendritic cells controls immune tolerance 査読

Takashi Izawa, Naozurni Ishimaru, Keiji Moriyama, Masayuki Kohashi, Rieko Arakaki, Yoshio Hayashi

BLOOD 110 ( 1 ) 242 - 250 2007年7月

顎関節症の歯科矯正患者の臨床統計学的研究(Clinico-statistical study of orthodontic patients with temporomandibular joint disorders) 査読

Tsuji Keiko, Satake Hidetaka, Fujihara Shinji, Izawa Takashi, Horiuchi Shinya, Moriyama Keiji

日本顎関節学会雑誌 19 ( 1 ) 82 - 82 2007年4月

関節リウマチ〜基礎解析からの新知見 MRL/lprマウスにおける自己免疫性関節炎に対するRANKL刺激樹状細胞の免疫制御的役割(Immunoregulatory role of RANKL-stimulated dendritic cells on autoimmune arthritis in MRL/lpr mice) 査読

Izawa Takashi, Ishimaru Naozumi, Arakaki Rieko, Moriyama Keiji, Hayashi Yoshio

日本免疫学会総会・学術集会記録 36 284 - 284 2006年11月

関節炎モデルマウスを用いた樹状細胞移入による関節リウマチ病態の修飾査読

大嶋淳, 井澤俊, 石丸直澄, 林良夫, 森山啓司

日本矯正歯科学会大会プログラム・抄録集 65回 217 - 217 2006年9月

関節円板前方転位を有する顎関節症患者の顎顔面形態の特徴について査読

辻けい子, 井澤俊, 細木秀彦, 前田直樹, 佐竹秀太, 堀内信也, 森山啓司

日本顎関節学会雑誌 18 ( 1 ) 83 - 83 2006年4月

RANKL刺激活性化DCを介したMRL/lprマウス関節炎の病態修飾査読

井澤俊, 石丸直澄, 表原文江, 新垣理恵子, 大嶋淳, 森山啓司, 林良夫

日本免疫学会総会・学術集会記録 35 249 - 249 2005年11月

関節リウマチ自然発症モデルマウスを用いた関節骨破壊機構の解析査読

井澤俊, 林良夫, 森山啓司

日本口腔科学会雑誌 54 ( 4 ) 495 - 496 2005年9月

上顎前突症患者におけるBite jumping applianceとElastic open activator の作用機序に関する比較検討査読

井澤俊, 辻けい子, 山内里津, 堀内信也, 森山啓司

中・四国矯正歯科学会雑誌 17 ( 1 ) 15 - 23 2005年8月

関節リウマチ自然発症モデルマウスを用いた関節骨破壊機構の解析査読

井澤俊, 大嶋淳, 森山啓司

日本顎関節学会雑誌 17 ( 1 ) 57 - 57 2005年4月

下垂体腫瘍に伴う反対咬合2症例の矯正治療(Two orthodontic treatment cases of reversed occlusion associated with the pituitary tumor) 査読

Yasue Akihiro, Horiuchi Shinya, Izawa Takashi, Oba Yasuo, Moriyama Keiji

日本矯正歯科学会大会プログラム・抄録集 63回 101 - 101 2004年11月

上顎前突症患者におけるbite jumping applianceとelastic open activatorの治療効果に関する検討査読

井澤俊, 辻けい子, 山内里津, 堀内信也, 森山啓司

日本矯正歯科学会大会プログラム・抄録集 63回 247 - 247 2004年11月

Estrogen deficiency accelerates murine autoimmune arthritis associated with receptor activator of nuclear Factor-kappa B ligand-mediated osteoclastogenesis 査読

T Yoneda, N Ishimaru, R Arakaki, M Kobayashi, T Izawa, K Moriyama, Y Hayashi

ENDOCRINOLOGY 145 ( 5 ) 2384 - 2391 2004年5月

シェーグレン症候群標的臓器におけるRbAp48遺伝子の役割

林良夫, 石丸直澄, 新垣理恵子, 井澤俊, 渡邊恵

日本免疫学会総会・学術集会記録 33 286 - 286 2003年11月

RANKL刺激樹状細胞移入によるMRL/lprマウス自己免疫性関節炎の病態修飾

井澤俊, 石丸直澄, 新垣理恵子, 林良夫

日本免疫学会総会・学術集会記録 33 225 - 225 2003年11月

RANKL刺激樹状細胞移入によるMRL/lprマウス自己免疫性関節炎の病態修飾査読

井澤俊, 林良夫, 森山啓司

日本矯正歯科学会大会プログラム・抄録集 62回 215 - 215 2003年10月

RANKL刺激活性化樹状細胞移入MRL/lprマウスにおける自己免疫性関節炎の病態解析

井澤俊, 石丸直澄, 小林大, 新垣理恵子, 林良夫

日本免疫学会総会・学術集会記録 32 293 - 293 2002年10月

RANKL刺激による活性化樹状細胞を用いたMRL/lprマウス関節病変の増悪

井澤俊, 渡邊恵, 石丸直澄, 美島健二, 新垣理恵子, 小林大, 斉藤一郎, 林良夫

日本病理学会会誌 91 ( 1 ) 202 - 202 2002年3月

エストロジェン欠乏マウスにおけるシェーグレン症候群新規疾患モデル確立の試み

石丸直澄, 井澤俊, 渡邊恵, 柳久美子, 新垣理恵子, 美島健二, 斉藤一郎, 林良夫

日本病理学会会誌 91 ( 1 ) 202 - 202 2002年3月

RANKL刺激による活性化樹状細胞を用いたMRL/lprマウス関節病変の増悪

井澤俊, 石丸直澄, 小林大, 柳久美子, 斉藤一郎, 林良夫

日本免疫学会総会・学術集会記録 31 58 - 58 2001年12月

卵巣摘出C57BL/6マウスにおける実験的シェーグレン症候群の誘発

石丸直澄, 柳久美子, 井澤俊, 新垣理恵子, 斉藤一郎, 林良夫

日本免疫学会総会・学術集会記録 31 207 - 207 2001年12月

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