Papers - EMA Tadashi
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Mechanism of enantioselectivity of lipases and other synthetically useful hydrolases
Tadashi Ema
Current Organic Chemistry 8 ( 11 ) 1009 - 1025 2004.7
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The effect of temperature on the lipase-catalyzed asymmetric protonation of 1-acetoxy-2-methylcyclohexene giving (R)-2-methylcyclohexanone
Takashi Sakai, Akiko Matsuda, Yuko Tanaka, Toshinobu Korenaga, Tadashi Ema
Tetrahedron Asymmetry 15 ( 12 ) 1929 - 1932 2004.6
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Synthesis of enantiomerically pure (R,R)- and (S,S)-1,2-Bis(pentafluorophenyl)ethane-1,2-diamine and evaluation of the pK <inf>a</inf> value by ab initio calculations
Takashi Sakai, Toshinobu Korenaga, Noriyuki Washio, Yuji Nishio, Shinichi Minami, Tadashi Ema
Bulletin of the Chemical Society of Japan 77 ( 5 ) 1001 - 1008 2004
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Highly enantioselective lipase-catalyzed reactions at high temperatures up to 120°C in organic solvent
Tadashi Ema, Masafumi Kageyama, Toshinobu Korenaga, Takashi Sakai
Tetrahedron Asymmetry 14 ( 24 ) 3943 - 3947 2003.12
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Intermolecular oxygen atom⋯π interaction in the crystal packing of chiral amino alcohol bearing a pentafluorophenyl group
Toshinobu Korenaga, Hikaru Tanaka, Tadashi Ema, Takashi Sakai
Journal of Fluorine Chemistry 122 ( 2 ) 201 - 205 2003.8
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Enhancement of the efficiency of the low temperature method for kinetic resolution of primary alcohols by optimizing the organic bridges in porous ceramic-immobilized lipase
Takashi Sakai, Kyoko Hayashi, Fumika Yano, Mie Takami, Megumi Ino, Toshinobu Korenaga, Tadashi Ema
Bulletin of the Chemical Society of Japan 76 ( 7 ) 1441 - 1446 2003.7
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Transition-state models are useful for versatile biocatalysts: Kinetics and thermodynamics of enantioselective acylations of secondary alcohols catalyzed by lipase and subtilisin
Tadashi Ema, Kunihiro Yamaguchi, Yuji Wakasa, Akinori Yabe, Ryoichi Okada, Minoru Fukumoto, Fumika Yano, Toshinobu Korenaga, Masanori Utaka, Takashi Sakai
Journal of Molecular Catalysis B: Enzymatic 22 ( 3-4 ) 181 - 192 2003.6
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Practical resolution of 3-phenyl-2H-azirine-2-methanol at very low temperature by using lipase immobilized on porous ceramic and optimized acylating agent
Takashi Sakai, Akiko Matsuda, Toshinobu Korenaga, Tadashi Ema
Bulletin of the Chemical Society of Japan 76 ( 9 ) 1819 - 1821 2003
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Mechanism-based enzymatic method for reliable determination of absolute configuration of chiral 1-substituted ethanols: Combination with NMR method
Tadashi Ema, Masataka Yoshii, Toshinobu Korenaga, Takashi Sakai
Tetrahedron Asymmetry 13 ( 11 ) 1223 - 1229 2002.6
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5-[4-(1-Hydroxyethyl)phenyl]-10,15,20-triphenylporphyrin as a probe of the transition-state conformation in hydrolase-catalyzed enantioselective transesterifications
Tadashi Ema, Masahito Jittani, Kenji Furuie, Masanori Utaka, Takashi Sakai
Journal of Organic Chemistry 67 ( 7 ) 2144 - 2151 2002.4
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High enantioselectivity and broad substrate specificity of a carbonyl reductase: Toward a versatile biocatalyst
T. Ema, H. Moriya, T. Kofukuda, T. Ishida, K. Maehara, M. Utaka, T. Sakai
Journal of Organic Chemistry 66 ( 25 ) 8682 - 8684 2001.12
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Lipase-catalyzed transesterification of 2-hydroxy-2- (pentafluorophenyl)acetonitrile leading to (1R,2R)-and (1S,2S)-bis (pentafluorophenyl)ethane-1,2-diol
Takashi Sakai, Yasushi Miki, Masashi Tsuboi, Hiroaki Takeuchi, Tadashi Ema, Kenji Uneyama, Masanori Utaka
Journal of Organic Chemistry 65 ( 9 ) 2740 - 2747 2000.5
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Compensation effect between differential activation enthalpy and entropy in subtilisin-catalyzed kinetic resolutions of secondary alcohols
Tadashi Ema, Kunihiro Yamaguchi, Yuji Wakasa, Nobuaki Tanaka, Masanori Utaka, Takashi Sakai
Chemistry Letters ( 7 ) 782 - 783 2000
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Transition-state model for subtilisin-catalyzed transesterifications of secondary alcohols
Ema Tadashi, Ryoichi Okada, Minoru Fukumoto, Masahito Jittani, Mikiko Ishida, Kenji Furuie, Kunihiro Yamaguchi, Takashi Sakai, Masanori Utaka
Tetrahedron Letters 40 ( 23 ) 4367 - 4370 1999.6
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Low-temperature method for enhancement of enantioselectivity in the lipase-catalyzed kinetic resolutions of solketal and some chiral alcohols
Takashi Sakai, Tetsuo Kishimoto, Yukie Tanaka, Tadashi Ema, Masanori Utaka
Tetrahedron Letters 39 ( 43 ) 7881 - 7884 1998.10
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Lipase-catalyzed kinetic resolution of large secondary alcohols having tetraphenylporphyrin
Tadashi Ema, Masahito Jittani, Takashi Sakai, Masanori Utaka
Tetrahedron Letters 39 ( 35 ) 6311 - 6314 1998.8
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Control of enantioselectivity in the baker's yeast asymmetric reduction of γ-chloro β-diketones to γ-chloro (S)-β-hydroxy ketones
Jing Nan Cui, Tadashi Ema, Takashi Sakai, Masanori Utaka
Tetrahedron Asymmetry 9 ( 15 ) 2681 - 2692 1998.8
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Highly Enantioselective Reduction of Carbonyl Compounds Using a Reductase Purified from Bakers' Yeast
Tadashi Ema, Yasushi Sugiyama, Minoru Fukumoto, Hiroyuki Moriya, Jing Nan Cui, Takashi Sakai, Masanori Utaka
Journal of Organic Chemistry 63 ( 15 ) 4996 - 5000 1998.7
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Lipase-catalyzed kinetic resolution of 2-acyloxy-2- (pentafluorophenyl)acetonitrile
Takashi Sakai, Yasushi Miki, Mayumi Nakatani, Tadashi Ema, Kenji Uneyama, Masanori Utaka
Tetrahedron Letters 39 ( 29 ) 5233 - 5236 1998.7
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Origin of the Enantioselectivity of Lipases Explained by a Stereo-Sensing Mechanism Operative at the Transition State
Tadashi Ema, Juka Kobayashi, Soichi Maeno, Takashi Sakai, Masanori Utaka
Bulletin of the Chemical Society of Japan 71 ( 2 ) 443 - 453 1998.2