Papers - EMA Tadashi
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Highly efficient chemoenzymatic synthesis of methyl (R)-o-chloromandelate, a key intermediate for clopidogrel, via asymmetric reduction with recombinant Escherichia coli
Tadashi Ema, Sayaka Ide, Nobuyasu Okita, Takashi Sakai
Advanced Synthesis and Catalysis 350 ( 13 ) 2039 - 2044 2008.9
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Lipase-catalyzed dynamic kinetic resolution giving optically active cyanohydrins: use of silica-supported ammonium hydroxide and porous ceramic-immobilized lipase
Takashi Sakai, Kefei Wang, Tadashi Ema
Tetrahedron 64 ( 9 ) 2178 - 2183 2008.2
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Hydrolase-catalyzed kinetic resolution of 5-[4-(1-hydroxyethyl)phenyl]-10, 15,20-tris(pentafluorophenyl)porphyrin in ionic liquids
Tadashi Ema, Tokuhiro Doi, Takashi Sakai
Chemistry Letters 37 ( 1 ) 90 - 91 2008.1
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Chiral selector with multiple hydrogen-bonding sites in a macrocyclic cavity
Tadashi Ema, Daisuke Tanida, Kyoko Sugita, Takashi Sakai, Ken Ichiro Miyazawa, Atsushi Ohnishi
Organic Letters 10 ( 12 ) 2365 - 2368 2008
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Biomimetic trifunctional organocatalyst showing a great acceleration for the transesterification between vinyl ester and alcohol
Tadashi Ema, Daisuke Tanida, Tatsuya Matsukawa, Takashi Sakai
Chemical Communications ( 8 ) 957 - 959 2008
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Highly active and robust organic-inorganic hybrid catalyst for the synthesis of cyclic carbonates from carbon dioxide and epoxides
Takashi Sakai, Yoshihiro Tsutsumi, Tadashi Ema
Green Chemistry 10 ( 3 ) 345 - 349 2008
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Versatile and practical macrocyclic reagent with multiple hydrogen-bonding sites for chiral discrimination in NMR
Tadashi Ema, Daisuke Tanida, Takashi Sakai
Journal of the American Chemical Society 129 ( 34 ) 10591 - 10596 2007.8
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Highly enantioselective and efficient synthesis of methyl (R)-o-chloromandelate with recombinant E. coli: Toward practical and green access to clopidogrel
Tadashi Ema, Nobuyasu Okita, Sayaka Ide, Takashi Sakai
Organic and Biomolecular Chemistry 5 ( 8 ) 1175 - 1176 2007
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Versatile and practical chiral shift reagent with hydrogen-bond donor/acceptor sites in a macrocyclic cavity
Tadashi Ema, Daisuke Tanida, Takashi Sakai
Organic Letters 8 ( 17 ) 3773 - 3775 2006.8
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Asymmetric reduction of ketones using recombinant E. coli cells that produce a versatile carbonyl reductase with high enantioselectivity and broad substrate specificity
Tadashi Ema, Hideo Yagasaki, Nobuyasu Okita, Masahiro Takeda, Takashi Sakai
Tetrahedron 62 ( 26 ) 6143 - 6149 2006.6
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Synthesis of molecular tweezers bearing pentafluorophenyl and several pendant aryl groups. Effective application of the modified Suzuki-Miyaura coupling reaction
Toshinobu Korenaga, Takahiro Kosaki, Yusuke Kawauchi, Tadashi Ema, Takashi Sakai
Journal of Fluorine Chemistry 127 ( 4-5 SPEC. ISS. ) 604 - 609 2006.5
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Suzuki-Miyaura coupling reaction using pentafluorophenylboronic acid
Toshinobu Korenaga, Takahiro Kosaki, Rokki Fukumura, Tadashi Ema, Takashi Sakai
Organic Letters 7 ( 22 ) 4915 - 4917 2005.10
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Rational control of enantioselectivity of lipase by site-directed mutagenesis based on the mechanism
Tadashi Ema, Toshiyuki Fujii, Misa Ozaki, Toshinobu Korenaga, Takashi Sakai
Chemical Communications ( 37 ) 4650 - 4651 2005.10
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Highly sensitive chiral shift reagent bearing two zinc porphyrins
Tadashi Ema, Nozomi Ouchi, Tokuhiro Doi, Toshinobu Korenaga, Takashi Sakai
Organic Letters 7 ( 18 ) 3985 - 3988 2005.9
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Kinetic resolution of 5-(hydroxymethyl)-3-phenyl-2-isoxazoline by using the 'low-temperature method' with porous ceramic-immobilized lipase
Takashi Sakai, Hiroshi Mitsutomi, Toshinobu Korenaga, Tadashi Ema
Tetrahedron Asymmetry 16 ( 8 ) 1535 - 1539 2005.4
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Asymmetric reduction of a variety of ketones with a recombinant carbonyl reductase: Identification of the gene encoding a versatile biocatalyst
Tadashi Ema, Hideo Yagasaki, Nobuyasu Okita, Kumiko Nishikawa, Toshinobu Korenaga, Takashi Sakai
Tetrahedron Asymmetry 16 ( 6 ) 1075 - 1078 2005.3
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Lipase-catalyzed resolution of (2R*,3S*)- and (2R*,3R*)-3-methyl-3-phenyl-2-aziridinemethanol at low temperatures and determination of the absolute configurations of the four stereoisomers
Takashi Sakai, Yu Liu, Hiroshi Ohta, Toshinobu Korenaga, Tadashi Ema
Journal of Organic Chemistry 70 ( 4 ) 1369 - 1375 2005.2
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Synthesis of a molecular tweezer containing pentafluorophenyl groups and investigation of the π-π stacking interaction for a pentafluorophenyl group in a polar organic solvent
Toshinobu Korenaga, Yusuke Kawauchi, Takahiro Kosaki, Tadashi Ema, Takashi Sakai
Bulletin of the Chemical Society of Japan 78 ( 12 ) 2175 - 2179 2005
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Reestimation of the Taft's substituent constant of the pentafluorophenyl group
Toshinobu Korenaga, Koichi Kadowaki, Tadashi Ema, Takashi Sakai
Journal of Organic Chemistry 69 ( 21 ) 7340 - 7343 2004.10
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Rational strategies for highly enantioselective lipase-catalyzed kinetic resolutions of very bulky chiral compounds: Substrate design and high-temperature biocatalysis
Tadashi Ema
Tetrahedron Asymmetry 15 ( 18 ) 2765 - 2770 2004.9