Organization
Faculty of Medicine, Dentistry and Pharmaceutical Sciences Assistant
Position
Assistant
External link
NISHIOKA Hiromi
Degree
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薬学博士 ( 岡山大学 )
Research Interests
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有機化学
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Synthetic Chemistry
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Organic Chemistry
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合成化学
Research Areas
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Life Science / Pharmaceutical chemistry and drug development sciences
Education
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Okayama University
- 1992
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Okayama University 薬学部 製薬化学科
- 1992
Country： Japan
Research History
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Okayama University 学術研究院医歯薬学域 Research Assistant
2022.4
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Okayama University 学術研究院医歯薬学域 Assistant Professor
2021.4 - 2022.3
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Okayama University 医歯薬学総合研究科 Assistant Professor
2004.4 - 2021.3
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- Assistant Professor,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
2004
Professional Memberships
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有機合成化学協会
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日本薬学会
Papers
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Competitive binding assay with an umbelliferone-based fluorescent rexinoid for retinoid X receptor ligand screening Reviewed
Shoya Yamada, Mayu Kawasaki, Michiko Fujihara, Masaki Watanabe, Yuta Takamura, Maho Takioku, Hiromi Nishioka, Yasuo Takeuchi, Makoto Makishima, Tomoharu Motoyama, Sohei Ito, Hiroaki Tokiwa, Shogo Nakano, Hiroki Kakuta
Journal of Medicinal Chemistry 62 ( 19 ) 8809 - 8818 2019.9
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Correction to Synthesis of 11C-Labeled RXR Partial Agonist 1-[(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino]benzotriazole-5-carboxylic Acid (CBt-PMN) by Direct [11C]Carbon Dioxide Fixation via Organolithiation of Tri Reviewed
Shibahara O, Watanabe M, Takamura Y, Yamada S, Akehi M, Sasaki T, Akahoshi A, Hanada T, Hirano H, Nakatani S, Nishioka H, Takeuchi Y, Kakuta H
Journal of medicinal chemistry 62 ( 9 ) 4780 - 4781 2019.5
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Structure-activity relationship of indoloquinoline analogs anti-MRSA Reviewed
Zhao M, Kamada T, Takeuchi A, Nishioka H, Kuroda T, Takeuchi Y
Bioorg. Med. Chem. Lett. 25 5551 - 5554 2015.6
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Palladium-catalyzed hydrogenation with use of ionic liquid bis(2-hydroxyethyl)ammonium formate [BHEA][HCO2] as a solvent and hydrogen source Reviewed
Hideyuki Suzuki, Seiki Yoshioka, Ami Igesaka, Hiromi Nishioka, Yasuo Takeuchi
TETRAHEDRON 69 ( 31 ) 6399 - 6403 2013.8
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Non-flammable and reusable hydrogenation of aromatic ketones in ionic liquid Reviewed
Hideyuki Suzuki, Hiromi Nishioka, Yasuo Takeuchi
TETRAHEDRON LETTERS 53 ( 28 ) 3686 - 3688 2012.7
MISC
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Controlled hydrogenation of diphenylacetylene using alkylammonium formate
Hideyuki Suzuki, Ikkyu Satoh, Hiromi Nishioka, Yasuo Takeuchi
TETRAHEDRON LETTERS 58 ( 40 ) 3834 - 3837 2017.10
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Synthesis of C-11-Labeled RXR Partial Agonist 14(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)aminoThenzotriazole-5-carboxylic Acid (CBt-PMN) by Direct [C-11]Carbon Dioxide Fixation via Organolithiation of Trialkyltin Precursor and PET Imaging Thereof
Osamu Shibahara, Masaki Watanabe, Shoya Yamada, Masaru Akehi, Takanori Sasaki, Akiya Akahoshi, Takahisa Hanada, Hiroyuki Hirano, Shunsuke Nakatani, Hiromi Nishioka, Yasuo Takeuchi, Hiroki Kakuta
JOURNAL OF MEDICINAL CHEMISTRY 60 ( 16 ) 7139 - 7145 2017.8
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Synthesis and Anti-human Immunodeficiency Virus Activity of the Skeleton Isomers of 3 ',4 '-Di-(O)-(-)-camphanoyl-(+)-khellactone
Hiromi Nishioka, Koji Uesugi, Norihiro Ueda, Yuka Kondo, Megumi Tsuji, Hitoshi Abe, Takashi Harayama, Takayuki Hamasaki, Masanori Baba, Yasuo Takeuchi
CHEMICAL & PHARMACEUTICAL BULLETIN 59 ( 8 ) 1075 - 1076 2011.8
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Synthesis of (-)-Actinonin
Shin-ichi Inoue, Hiromi Nishioka, Hitoshi Abe, Takashi Harayama, Yasuo Takeuchi
SYNTHESIS-STUTTGART 2011 ( 11 ) 1705 - 1710 2011.6
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Synthesis of acinetobactin
Yasuo Takeuchi, Satoru Ozaki, Masahiro Satoh, Ken-Ichiro Mimura, Sei-Ichi Hara, Hitoshi Abe, Hiromi Nishioka, Takashi Harayama
Chemical and Pharmaceutical Bulletin 58 ( 11 ) 1552 - 1553 2010.11
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Concise Asymmetric Synthesis of (+)-Febrifugine Utilizing trans-Selective Intramolecular Conjugate Addition
Satoshi Sukemoto, Miyo Shige, Masahiro Sato, Ken-ichiro Mimura, Hiromi Nishioka, Hitoshi Abe, Takashi Harayama, Yasuo Takeuchi
SYNTHESIS-STUTTGART 2008 ( 19 ) 3081 - 3087 2008.10
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Studies toward the synthesis of toddaquinoline by intramolecular cyclization
Georgeta Serban, Yasurni Shigeta, Hiromi Nishioka, Hitoshi Abe, Yasuo Takeuchi, Takashi Harayama
HETEROCYCLES 71 ( 7 ) 1623 - 1630 2007.7
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Biaryl coupling reactions of 3-methoxy-N-(2-iodophenyl)-N-methylbenzamide and 3-methoxycarbonyl-N-(2-iodophenyl)-N-methylbenzamide using palladium reagent
Hiromi Nishioka, Chie Nagura, Hitoshi Abe, Yasuo Takeuchi, Takashi Harayama
HETEROCYCLES 70 549 - + 2006.12
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Novel synthesis of benzoxazoles from O-nitrophenols and amines
H Nishioka, Y Ohmori, Y Iba, E Tsuda, T Harayama
HETEROCYCLES 64 193 - 198 2004.12
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Intramolecular Pd-catalyzed biaryl coupling reaction of N-aryl-2-triflyloxybenzamides using Pd(OAc)(2) 1,3-bis[diphenylphosphino]propane, Bu3P, and DBU
H Nishioka, Y Shoujiguchi, H Abe, Y Takeuchi, T Harayama
HETEROCYCLES 64 463 - 466 2004.12
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Synthetic studies on pyrrolophenanthridone skeleton from 1-benzoyl-7-iododihydroindole derivatives using palladium-assisted biaryl coupling reactions
T Harayama, H Toko, A Hori, T Miyagoe, T Sato, H Nishioka, H Abe, Y Takeuchi
HETEROCYCLES 61 513 - + 2003.12
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Concise synthesis of tetrahydrophenanthridone by palladium reagent
T Harayama, H Toko, H Nishioka, H Abe, Y Takeuchi
HETEROCYCLES 59 ( 2 ) 541 - 546 2003.3
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Synthesis of febrifugine derivatives and a solution to the puzzle of the structural determination of febrifugine
Y Takeuchi, K Azuma, M Oshige, H Abe, H Nishioka, K Sasaki, T Harayama
TETRAHEDRON 59 ( 10 ) 1639 - 1646 2003.3
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Convenient synthesis of a simple coumarin from salicylaldehyde and Wittig reagent. IV: Improved synthetic method of substituted coumarins
Y Takeuchi, N Ueda, K Uesugi, H Abe, H Nishioka, T Harayama
HETEROCYCLES 59 ( 1 ) 217 - 224 2003.1
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Concise Synthesis of 11H-Indolizino[1,2-b]quinolin-9-one by an Aryl-Aryl Coupling Reaction Using Pd Reagent
Takashi Harayama, Yoshiaki Morikami, Akihiro Hori, Hiromi Nishioka, Hitoshi Abe, Yasuo Takeuchi
Heterocycles 2003
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Studies on the selective intramolecular biaryl coupling reaction of 2-triflyloxy-6-halobenzanilides using a palladium reagent
T Harayama, H Toko, K Kubota, H Nishioka, H Abe, Y Takeuchi
HETEROCYCLES 58 175 - 181 2002.11
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Aryl-aryl coupling reaction using a novel and highly active palladium reagent prepared from Pd(OAc)(2), 1,3-bis [diphenylphosphino]propane (DPPP), and Bu3P
T Harayama, T Akiyama, Y Nakano, H Nishioka, H Abe, Y Takeuchi
CHEMICAL & PHARMACEUTICAL BULLETIN 50 ( 4 ) 519 - 522 2002.4
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Synthesis and antimalarial activity of febrifugine derivatives
Y Takeuchi, M Koike, K Azuma, H Nishioka, H Abe, HS Kim, Y Wataya, T Harayama
CHEMICAL & PHARMACEUTICAL BULLETIN 49 ( 6 ) 721 - 725 2001.6
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Synthesis and siderophore activity of vibrioferrin and one of its diastereomeric isomers
Y Takeuchi, Y Nagao, K Toma, Y Yoshikawa, T Akiyama, H Nishioka, H Abe, T Harayama, S Yamamoto
CHEMICAL & PHARMACEUTICAL BULLETIN 47 ( 9 ) 1284 - 1287 1999.9
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Baeyer-Villiger reaction of benzaldehydes possessing oxygen functions with SeO2-H2O2
H Nishioka, K Katsuno, M Fujii, Y Nishita, N Koshiba, T Narayama
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN 119 ( 7 ) 519 - 528 1999.7
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SYNTHETIC STUDIES ON BROMOCOUMARINS POSSESSING OXYGEN FUNCTION
H NISHIOKA, N HAYASHIDA, S KAWABE, T HARAYAMA
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN 115 ( 9 ) 765 - 772 1995.9
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CONVENIENT SYNTHESIS OF A SIMPLE COUMARIN FROM SALICYLALDEHYDE AND WITTIG REAGENT .3. SYNTHESIS OF NITROCOUMARINS
T HARAYAMA, K NAKATSUKA, H NISHIOKA, K MURAKAMI, Y OHMORI, Y TAKEUCHI, H ISHII, K KENMOTSU
HETEROCYCLES 38 ( 12 ) 2729 - 2738 1994.12
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CONVENIENT SYNTHESIS OF A SIMPLE COUMARIN FROM SALICYLALDEHYDE AND WITTIG REAGENT .2. SYNTHESIS OF BROMOCOUMARIN AND METHOXYCARBONYLCOUMARIN
T HARAYAMA, K NAKATSUKA, H NISHIOKA, K MURAKAMI, N HAYASHIDA, H ISHII
CHEMICAL & PHARMACEUTICAL BULLETIN 42 ( 10 ) 2170 - 2173 1994.10
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ALKOXYCARBONYLMETHYLATION OF (3R,10BS)-3-PHENYL-2,3,5,6-TETRAHYDRO-10BH-OXAZOLO[2,3-A]ISOQUINOLINE
Y TAKEUCHI, Y KAMADA, K NISHIMURA, H NISHIOKA, M NISHIKAWA, K HASHIGAKI, M YAMATO, T HARAYAMA
CHEMICAL & PHARMACEUTICAL BULLETIN 42 ( 4 ) 796 - 801 1994.4
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A CONVENIENT PREPARATION OF SALICYLALDEHYDES FROM 2-METHYLBENZOFURANS BY OZONOLYSIS
H ISHII, S OHTA, H NISHIOKA, N HAYASHIDA, T HARAYAMA
CHEMICAL & PHARMACEUTICAL BULLETIN 41 ( 6 ) 1166 - 1168 1993.6
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A Convenient Synthesis of Coumarin Using the Wittig Reagent.
Chemistry Express 8 ( 4 ) 245 1993
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On the Products of Reaction of Ortho-Nitrophenols with Amines.
Chemistry Express 8 ( 9 ) 769 1993
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A Convenient Synthesis of Coumarin Using the Wittig Reagent.
Chemistry Express 8 ( 4 ) 245 1993
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On the Products of Reaction of Ortho-Nitrophenols with Amines.
Chemistry Express 8 ( 9 ) 769 1993
Presentations
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Pd反応系を用いたビアリール閉環反応における有機塩基の影響
日本薬学会第124年会 2004
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Wittig 試薬を用いた Coumarin 環形成反応における酸素官能基の影響
第３９回日本薬学会・日本病院薬剤師会中国四国支部学術大会 2000
Class subject in charge
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Experimental Organic Chemistry （2025academic year） 1st and 2nd semester - その他5～9
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Experimental Organic Chemistry （2025academic year） 1st and 2nd semester - その他5～9
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Clinical preparation education 5 （2025academic year） special - その他
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Clinical preparation education C （2025academic year） special - その他
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Clinical preparation education III （2025academic year） special - その他
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Basic Practice in Pharmaceutical Sciences （2025academic year） 1st semester - その他5～9
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Basic Practice in Pharmaceutical Sciences （2025academic year） 1st semester - その他5～9
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Basic Practice in Pharmaceutical Sciences （2025academic year） 1st semester - その他5～9
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Basic Practice in Pharmaceutical Sciences （2025academic year） 1st semester - その他5～9
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Practice in Fundamental Pharmaceutical Sciences II （2025academic year） 1st and 2nd semester - その他5～9
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Practice in Fundamental Pharmaceutical Sciences II （2025academic year） 1st and 2nd semester - その他5～9
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Experimental Organic Chemistry （2024academic year） 1st and 2nd semester - その他5～9
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Experimental Organic Chemistry （2024academic year） 1st and 2nd semester - その他5～9
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Clinical preparation education C （2024academic year） special - その他
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Basic Practice in Pharmaceutical Sciences （2024academic year） 1st semester - その他5～9
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Basic Practice in Pharmaceutical Sciences （2024academic year） 1st semester - その他5～9
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Basic Practice in Pharmaceutical Sciences （2024academic year） 1st semester - その他5～9
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Basic Practice in Pharmaceutical Sciences （2024academic year） 1st semester - その他5～9
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Practice in Fundamental Pharmaceutical Sciences II （2024academic year） 1st and 2nd semester - その他5～9
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Practice in Fundamental Pharmaceutical Sciences II （2024academic year） 1st and 2nd semester - その他5～9
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Experimental Organic Chemistry （2023academic year） 1st and 2nd semester - その他5～9
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Experimental Organic Chemistry （2023academic year） 1st and 2nd semester - その他5～9
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Basic Practice in Pharmaceutical Sciences （2023academic year） 1st semester - その他5～9
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Basic Practice in Pharmaceutical Sciences （2023academic year） 1st semester - その他5～9
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Basic Practice in Pharmaceutical Sciences （2023academic year） 1st semester - その他5～9
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Basic Practice in Pharmaceutical Sciences （2023academic year） 1st semester - その他5～9
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Practice in Fundamental Pharmaceutical Sciences II （2023academic year） 1st and 2nd semester - その他5～9
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Practice in Fundamental Pharmaceutical Sciences II （2023academic year） 1st and 2nd semester - その他5～9
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Development of Synthetic Drug I （2022academic year） special - その他
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Development of Synthetic Drug II （2022academic year） special - その他
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薬学基本実習 （2022academic year） 第１学期 - その他5～9
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薬学基本実習 （2022academic year） 第１学期 - その他5～9
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薬学基礎実習II （2022academic year） １・２学期 - その他5～9
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薬学基礎実習II （2022academic year） １・２学期 - その他5～9
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Seminar in Molecular Structure Analysis （2021academic year） Fourth semester - 火3～4
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Seminar in Molecular Structure Analysis （2021academic year） Fourth semester - 火3～4
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Synthetic & Medicinal Chemistry （2021academic year） special - その他
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Seminar on Synthetic & Medicinal Chemistry （2021academic year） special - その他
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Development of Synthetic Drug I （2021academic year） special - その他
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Development of Synthetic Drug II （2021academic year） special - その他
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Ethics for Pharmacist （2021academic year） Second semester - その他
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Ethics for Pharmacist （2021academic year） Second semester - 火3～4
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Basic Practice in Pharmaceutical Sciences （2021academic year） 1-3 semesters - その他6～9
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Basic Practice in Pharmaceutical Sciences （2021academic year） 1-3 semesters - その他6～9
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Practice in Fundamental Pharmaceutical Sciences II （2021academic year） 1st and 2nd semester - その他6～9
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Practice in Fundamental Pharmaceutical Sciences II （2021academic year） 1st and 2nd semester - その他6～9
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Seminar in Molecular Structure Analysis （2020academic year） Fourth semester - その他
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Seminar in Molecular Structure Analysis （2020academic year） Fourth semester - その他
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Chemistry a La Carte （2020academic year） 1st semester - 月1,月2
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Structural Analysis of Medicine （2020academic year） 1st-4th semester - [第１学期]月1,月2, [第２学期]その他, [第３学期]その他, [第４学期]火3,火4
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Synthetic & Medicinal Chemistry （2020academic year） special - その他
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Seminar on Synthetic & Medicinal Chemistry （2020academic year） special - その他
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Development of Synthetic Drug I （2020academic year） special - その他
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Development of Synthetic Drug II （2020academic year） special - その他
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Ethics for Pharmacist （2020academic year） Second semester - 火3,火4
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Basic Practice in Pharmaceutical Sciences （2020academic year） special - その他
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Basic Practice in Pharmaceutical Sciences （2020academic year） special - その他
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Practice in Fundamental Pharmaceutical Sciences II （2020academic year） special - その他
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Practice in Fundamental Pharmaceutical Sciences II （2020academic year） special - その他