Updated on 2025/10/10

写真a

 
NEMOTO Michiko
 
Organization
Faculty of Environmental, Life, Natural Science and Technology Associate Professor
Position
Associate Professor
Profile
External link

Degree

  • 博士(工学) ( 2010.3   東京農工大学 )

  • 博士(工学)

Research Interests

  • Radular teeth

  • Diatom

  • Chiton

  • Biomineralization

Research Areas

  • Life Science / Aquatic life science

Education

  • Tokyo University of Agriculture and Technology   大学院工学府   生命工学専攻

    2007.4 - 2010.3

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  • Tokyo University of Agriculture and Technology   大学院工学府   生命工学専攻

    2005.4 - 2007.3

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  • Tokyo University of Agriculture and Technology   工学部   生命工学科

    2001.4 - 2005.3

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Research History

  • Okayama University   学術研究院環境生命自然科学学域   Associate Professor

    2023.4

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  • Okayama University   学術研究院環境生命科学学域   Associate Professor

    2022.1 - 2023.3

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  • Okayama University   The Graduate School of Environmental and Life Science   Assistant Professor

    2020.4 - 2021.12

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    Country:Japan

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  • Okayama University   The Graduate School of Environmental and Life Science

    2015.4 - 2020.3

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  • (独)国立病院機構 名古屋医療センター   流動研究員

    2013.4 - 2015.3

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  • Tokyo University of Agriculture and Technology

    2011.5 - 2013.3

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  • Tokyo University of Agriculture and Technology

    2010.4 - 2011.4

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Professional Memberships

  • 生命金属科学研究会

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  • JAPANESE SOCIETY FOR MARINE BIOTECHNOLOGY

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  • JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY

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  • The Society for Biotechnology, Japan

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Committee Memberships

  •   Journal of Bioscience and Bioengineering (Elsevier) Editor  

    2023.6   

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  • 日本生物工学会西日本支部   会計  

    2019.4 - 2021.3   

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    Committee type:Academic society

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Papers

  • Radular teeth matrix protein 1 directs iron oxide deposition in chiton teeth

    Michiko Nemoto, Koki Okada, Haruka Akamine, Yuki Odagaki, Yuka Narahara, Kenji Okoshi, Kiori Obuse, David Kisailus, Hisao Moriya, Akira Satoh

    SCIENCE   389 ( 6760 )   637 - 643   2025.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1126/science.adu0043

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  • Illumina-based transcriptomic analysis of the fast-growing leguminous tree Acacia crassicarpa: functional gene annotation and identification of novel SSR-markers

    Shougo Ishio, Kazutaka Kusunoki, Michiko Nemoto, Tadayoshi Kanao, Takashi Tamura

    Frontiers in Plant Science   15   2024.8

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    Publishing type:Research paper (scientific journal)   Publisher:Frontiers Media SA  

    Acacia crassicarpa is a fast-growing leguminous tree that is widely cultivated in tropical areas such as Indonesia, Malaysia, Australia, and southern China. This tree has versatile utility in timber, furniture, and pulp production. Illumina sequencing of A. crassicarpa was conducted, and the raw data of 124,410,892 reads were filtered and assembled de novo into 93,317 unigenes, with a total of 84,411,793 bases. Blast2GO annotation, Benchmark Universal Single-Copy Ortholog evaluation, and GO-term classification produced a catalogue of unigenes for studying primary metabolism, phytohormone signaling, and transcription factors. Massive transcriptomic analysis has identified microsatellites composed of simple sequence repeat (SSR) loci representing di-, tri-, and tetranucleotide repeat units in the predicted open reading frames. Polymorphism was induced by PCR amplification of microsatellite loci located in several genes encoding auxin response factors and other transcription factors, which successfully distinguished 16 local trees of A. crassicarpa tested, representing potentially exploitable molecular markers for efficient tree breeding for plantation and biomass exploitation.

    DOI: 10.3389/fpls.2024.1339958

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  • The Multiphasic Teeth of Chiton Articulatus, an Abrasion-Resistant and Self-Sharpening Tool for Hard Algae Collection Reviewed

    Devis Montroni, Ezra Sarmiento, Ruoheng Zhao, Phani Saketh Dasika, John Michael Connolly, Richard Wuhrer, Yugang Zhang, Mikhail Zhernenkov, Taifeng Wang, Brenda Paola Ramirez-Santana, Leigh Sheppard, Omar Hernando Avila-Poveda, Atsushi Arakaki, Michiko Nemoto, Pablo Zavattieri, David Kisailus

    Advanced Functional Materials   2024

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    DOI: 10.1002/adfm.202401658

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  • Nuclear Transformation of the Marine Pennate Diatom Nitzschia sp. Strain NIES-4635 by Multi-Pulse Electroporation Reviewed

    Koki Okada, Yu Morimoto, Yukine Shiraishi, Takashi Tamura, Shigeki Mayama, Takashi Kadono, Masao Adachi, Kentaro Ifuku, Michiko Nemoto

    Marine Biotechnology   2023.12

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)   Publisher:Springer Science and Business Media LLC  

    DOI: 10.1007/s10126-023-10273-w

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    Other Link: https://link.springer.com/article/10.1007/s10126-023-10273-w/fulltext.html

  • Fibrous anisotropy and mineral gradients Within the radula stylus of chiton: Controlled stiffness and damage tolerance in a flexible biological composite Reviewed

    Jung-Eun Lee, John Connolloy, Wen Yang, Guillaume Freychet, Taifeng Wang, Steven A. Herrera, Satoshi Murata, Phani Saketh Dasika, Devis Montroni, Anna Pohl, Chenhui Zhu, Mikhail Zhernenkov, Richard Wuhrer, Leigh Sheppard, Michiko Nemoto, Atsushi Arakaki, Pablo Zavattieri, David Kisailus

    JOURNAL OF COMPOSITE MATERIALS   2022.8

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    DOI: 10.1177/00219983221121867

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  • Evaluation of the Geenius HIV 1/2 confirmatory assay for HIV-2 samples isolated in Japan Reviewed

    Urara Shigemi, Yoshimi Yamamura, Masakazu Matsuda, Reiko Okazaki, Mai Kubota, Shiro Ibe, Michiko Nemoto, Masami Maejima-Kitagawa, Sayaka Sukegawa, Mayumi Imahashi, Tadashi Kikuchi, Wataru Sugiura, Yasumasa Iwatani, Atsuko Hachiya, Yoshiyuki Yokomaku

    Journal of Clinical Virology   152   105189 - 105189   2022.7

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    DOI: 10.1016/j.jcv.2022.105189

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  • Nanoarchitected Tough Biological Composites from Assembled Chitinous Scaffolds Reviewed

    Wei Huang, Devis Montroni, Taifeng Wang, Satoshi Murata, Atsushi Arakaki, Michiko Nemoto, David Kisailus

    ACCOUNTS OF CHEMICAL RESEARCH   55 ( 10 )   1360 - 1371   2022.5

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  • Mesocrystalline Ordering and Phase Transformation of Iron Oxide Biominerals in the Ultrahard Teeth of Cryptochiton stelleri Reviewed

    Taifeng Wang, Wei Huang, Cong Huy Pham, Satoshi Murata, Steven Herrera, Nathan D. Kirchhofer, Bassim Arkook, Dejan Stekovic, Mikhail E. Itkis, Nir Goldman, Luis Zepeda-Ruiz, Mikhail Zhernenkov, Michiko Nemoto, Atsushi Arakaki, David Kisailus

    SMALL STRUCTURES   3 ( 4 )   2022.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/sstr.202100202

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  • Correction to: Comparative Gene Analysis Focused on Silica Cell Wall Formation: Identification of Diatom-Specific SET Domain Protein Methyltransferases. International journal

    Michiko Nemoto, Sayako Iwaki, Hisao Moriya, Yuki Monden, Takashi Tamura, Kenji Inagaki, Shigeki Mayama, Kiori Obuse

    Marine biotechnology (New York, N.Y.)   23 ( 1 )   157 - 157   2021.2

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  • Multiple mutations in RNA polymerase β-subunit gene (rpoB) in Streptomyces incarnatus NRRL8089 enhance production of antiviral antibiotic sinefungin: modeling rif cluster region by density functional theory. Reviewed International journal

    Saori Ogawa, Hitomi Shimidzu, Koji Fukuda, Naoki Tsunekawa, Toshiyuki Hirano, Fumitoshi Sato, Kei Yura, Tomohisa Hasunuma, Kozo Ochi, Michio Yamamoto, Wataru Sakamoto, Kentaro Hashimoto, Hiroyuki Ogata, Tadayoshi Kanao, Michiko Nemoto, Kenji Inagaki, Takashi Tamura

    Bioscience, biotechnology, and biochemistry   2021.1

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    Streptomyces incarnatus NRRL8089 produces the antiviral, antifungal, antiprotozoal nucleoside antibiotic sinefungin. To enhance sinefungin production, multiple mutations were introduced to the rpoB gene encoding RNA polymerase (RNAP) β-subunit at the target residues, D447, S453, H457, and R460. Sparse regression analysis using elastic-net lasso-ridge penalties on previously reported H457X mutations identified a numeric parameter set, which suggested that H457R/Y/F may cause production enhancement. H457R/R460C mutation successfully enhanced the sinefungin production by 3-fold, while other groups of mutations, such as D447G/R460C or D447G/H457Y, made moderate or even negative effects. To identify why the rif cluster residues have diverse effects on sinefungin production, an RNAP/DNA/mRNA complex model was constructed by homology modeling and molecular dynamics simulation. The 4 residues were located near the mRNA strand. Density functional theory-based calculation suggested that D447, H457, and R460 are in direct contact with ribonucleotide, and partially positive charges are induced by negatively charged chain of mRNA.

    DOI: 10.1093/bbb/zbab011

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  • Impact of long-term antiretroviral therapy on gut and oral microbiotas in HIV-1-infected patients. Reviewed International journal

    Mayumi Imahashi, Hirotaka Ode, Ayumi Kobayashi, Michiko Nemoto, Masakazu Matsuda, Chieko Hashiba, Akiko Hamano, Yoshihiro Nakata, Mikiko Mori, Kento Seko, Masashi Nakahata, Ayumi Kogure, Yasuhito Tanaka, Wataru Sugiura, Yoshiyuki Yokomaku, Yasumasa Iwatani

    Scientific reports   11 ( 1 )   960 - 960   2021.1

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    In HIV-1-infected patients, antiretroviral therapy (ART) is a key factor that may impact commensal microbiota and cause the emergence of side effects. However, it is not fully understood how long-term ART regimens have diverse impacts on the microbial compositions over time. Here, we performed 16S ribosomal RNA gene sequencing of the fecal and salivary microbiomes in patients under different long-term ART. We found that ART, especially conventional nucleotide/nucleoside reverse transcriptase inhibitor (NRTI)-based ART, has remarkable impacts on fecal microbial diversity: decreased α-diversity and increased ß-diversity over time. In contrast, dynamic diversity changes in the salivary microbiome were not observed. Comparative analysis of bacterial genus compositions showed a propensity for Prevotella-enriched and Bacteroides-poor gut microbiotas in patients with ART over time. In addition, we observed a gradual reduction in Bacteroides but drastic increases in Succinivibrio and/or Megasphaera under conventional ART. These results suggest that ART, especially NRTI-based ART, has more suppressive impacts on microbiota composition and diversity in the gut than in the mouth, which potentially causes intestinal dysbiosis in patients. Therefore, NRTI-sparing ART, especially integrase strand transfer inhibitor (INSTI)- and/or non-nucleotide reverse transcriptase inhibitor (NNRTI)-containing regimens, might alleviate the burden of intestinal dysbiosis in HIV-1-infected patients under long-term ART.

    DOI: 10.1038/s41598-020-80247-8

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  • Radular stylus of Cryptochiton stelleri: A multifunctional lightweight and flexible fiber-reinforced composite. Reviewed International journal

    Anna Pohl, Steven A Herrera, David Restrepo, Ryo Negishi, Jae-Young Jung, Chris Salinas, Richard Wuhrer, Tomoko Yoshino, Joanna McKittrick, Atsushi Arakaki, Michiko Nemoto, Pablo Zavattieri, David Kisailus

    Journal of the mechanical behavior of biomedical materials   111   103991 - 103991   2020.7

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    Chitons are herbivorous invertebrates that use rows of ultrahard magnetite-based teeth connected to a flexible belt (radula) to rasp away algal deposits growing on and within rocky outcrops along coastlines around the world. Each tooth is attached to the radula by an organic structure (stylus) that provides mechanical support during feeding. However, the underlying structures within the stylus, and their subsequent function within the chiton have yet to be investigated. Here, we investigate the macrostructural architecture, the regional material and elemental distribution and subsequent nano-mechanical properties of the stylus from the Northern Pacific dwelling Cryptochiton stelleri. Using a combination of μ-CT imaging, optical and electron microscopy, as well as elemental analysis, we reveal that the stylus is a highly contoured tube, mainly composed of alpha-chitin fibers, with a complex density distribution. Nanoindentation reveals regiospecific and graded mechanical properties that can be correlated with both the elemental composition and material distribution. Finite element modeling shows that the unique macroscale architecture, material distribution and elemental gradients have been optimized to preserve the structural stability of this flexible, yet robust functionally-graded fiber-reinforced composite tube, providing effective function during rasping. Understanding these complex fiber-based structures offers promising blueprints for lightweight, multifunctional and integrated materials.

    DOI: 10.1016/j.jmbbm.2020.103991

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  • Comparative Gene Analysis Focused on Silica Cell Wall Formation: Identification of Diatom-Specific SET Domain Protein Methyltransferases. Reviewed International journal

    Michiko Nemoto, Sayako Iwaki, Hisao Moriya, Yuki Monden, Takashi Tamura, Kenji Inagaki, Shigeki Mayama, Kiori Obuse

    Marine biotechnology (New York, N.Y.)   2020.6

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    Silica cell walls of diatoms have attracted attention as a source of nanostructured functional materials and have immense potential for a variety of applications. Previous studies of silica cell wall formation have identified numerous involved proteins, but most of these proteins are species-specific and are not conserved among diatoms. However, because the basic process of diatom cell wall formation is common to all diatom species, ubiquitous proteins and molecules will reveal the mechanisms of cell wall formation. In this study, we assembled de novo transcriptomes of three diatom species, Nitzschia palea, Achnanthes kuwaitensis, and Pseudoleyanella lunata, and compared protein-coding genes of five genome-sequenced diatom species. These analyses revealed a number of diatom-specific genes that encode putative endoplasmic reticulum-targeting proteins. Significant numbers of these proteins showed homology to silicanin-1, which is a conserved diatom protein that reportedly contributes to cell wall formation. These proteins also included a previously unrecognized SET domain protein methyltransferase family that may regulate functions of cell wall formation-related proteins and long-chain polyamines. Proteomic analysis of cell wall-associated proteins in N. palea identified a protein that is also encoded by one of the diatom-specific genes. Expression analysis showed that candidate genes were upregulated in response to silicon, suggesting that these genes play roles in silica cell wall formation. These candidate genes can facilitate further investigations of silica cell wall formation in diatoms.

    DOI: 10.1007/s10126-020-09976-1

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  • Antiviral effect of sinefungin on in vitro growth of feline herpesvirus type 1. Reviewed

    Yudai Kuroda, Haruka Yamagata, Michiko Nemoto, Kenji Inagaki, Takashi Tamura, Ken Maeda

    The Journal of antibiotics   72 ( 12 )   981 - 985   2019.12

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    Feline herpesvirus type 1 (FHV-1) causes a potentially fatal disease in cats. Through the use of virus inhibition and cytotoxicity assays, sinefungin, a nucleoside antibiotic, was assessed for its potential to inhibit the growth of FHV-1. Sinefungin inhibited in vitro growth of FHV-1 most significantly over other animal viruses, such as feline infectious peritonitis virus, equine herpesvirus, pseudorabies virus and feline calicivirus. Our results revealed that sinefungin specifically suppressed the replication of FHV-1 after its adsorption to the host feline kidney cells in a dose-dependent manner without obvious cytotoxicity to the host cells. This antibiotic can potentially offer a highly effective treatment for animals infected with FHV-1, providing alternative medication to currently available antiviral therapies.

    DOI: 10.1038/s41429-019-0234-4

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  • Redox-tuning of oxidizing disulfide oxidoreductase generates a potent disulfide isomerase. Reviewed International journal

    Shinya Sutoh, Yuko Uemura, Yuko Yamaguchi, Asako Kiyotou, Rena Sugihara, Makiko Nagayasu, Mihoko Kurokawa, Koreaki Ito, Naoki Tsunekawa, Michiko Nemoto, Kenji Inagaki, Takashi Tamura

    Biochimica et biophysica acta. Proteins and proteomics   1867 ( 3 )   194 - 201   2019.3

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    DOI: 10.1016/j.bbapap.2018.12.005

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  • Integrated transcriptomic and proteomic analyses of a molecular mechanism of radular teeth biomineralization in Cryptochiton stelleri. Reviewed International journal

    Michiko Nemoto, Dongni Ren, Steven Herrera, Songqin Pan, Takashi Tamura, Kenji Inagaki, David Kisailus

    Scientific reports   9 ( 1 )   856 - 856   2019.1

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    DOI: 10.1038/s41598-018-37839-2

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  • Novel Compound Heterozygous TYK2 Mutations in Primary Immunodeficiency with T-Cell Lymphopenia Reviewed

    Hattori Hiroyoshi, Nemoto Michiko, Maeda Naoko, Akita Nobuhiro, Moritani Suzuko, Muramatsu Hideki, Kawasaki Tomonori, Maejima Masami, Ode Hirotaka, Hachiya Atsuko, Sugiura Wataru, Yokomaku Yoshiyuki, Iwatani Yasumasa, Horibe Keizo

    PEDIATRIC BLOOD & CANCER   65   S45   2018.11

  • Compound heterozygous TYK2 mutations underlie primary immunodeficiency with T-cell lymphopenia. Reviewed International journal

    Michiko Nemoto, Hiroyoshi Hattori, Naoko Maeda, Nobuhiro Akita, Hideki Muramatsu, Suzuko Moritani, Tomonori Kawasaki, Masami Maejima, Hirotaka Ode, Atsuko Hachiya, Wataru Sugiura, Yoshiyuki Yokomaku, Keizo Horibe, Yasumasa Iwatani

    Scientific reports   8 ( 1 )   6956 - 6956   2018.5

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    DOI: 10.1038/s41598-018-25260-8

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  • An Internal Sequence Region Catalytically Essential for the Human Selenophosphate Synthetase 2 Reviewed

    Muneaki Takahata, Michiko Nemoto, Kenji Inagaki, Takashi Tamura

    FREE RADICAL BIOLOGY AND MEDICINE   112   65 - 65   2017.11

  • Gene cloning, recombinant expression, purification and characterization of l-methionine decarboxylase from Streptomyces sp. 590. Reviewed International journal

    Masaya Hayashi, Akane Okada, Kumiko Yamamoto, Tomomi Okugochi, Chika Kusaka, Daizou Kudou, Michiko Nemoto, Junko Inagaki, Yuu Hirose, Toshihide Okajima, Takashi Tamura, Kenji Soda, Kenji Inagaki

    Journal of biochemistry   161 ( 4 )   389 - 398   2017.4

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    DOI: 10.1093/jb/mvw083

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  • A non-radioactive assay for selenophosphate synthetase activity using recombinant pyruvate pyrophosphate dikinase from Thermus thermophilus HB8. Reviewed International journal

    Saho Kamada, Takahiro Okugochi, Kaori Asano, Ryuta Tobe, Hisaaki Mihara, Michiko Nemoto, Kenji Inagaki, Takashi Tamura

    Bioscience, biotechnology, and biochemistry   80 ( 10 )   1970 - 2   2016.10

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    DOI: 10.1080/09168451.2016.1200458

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  • Molecular evolution of gas cavity in [NiFeSe] hydrogenases resurrected in silico. Reviewed International journal

    Takashi Tamura, Naoki Tsunekawa, Michiko Nemoto, Kenji Inagaki, Toshiyuki Hirano, Fumitoshi Sato

    Scientific reports   6   19742 - 19742   2016.1

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    DOI: 10.1038/srep19742

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  • Structural Insights into HIV-1 Vif-APOBEC3F Interaction. Reviewed International journal

    Masaaki Nakashima, Hirotaka Ode, Takashi Kawamura, Shingo Kitamura, Yuriko Naganawa, Hiroaki Awazu, Shinya Tsuzuki, Kazuhiro Matsuoka, Michiko Nemoto, Atsuko Hachiya, Wataru Sugiura, Yoshiyuki Yokomaku, Nobuhisa Watanabe, Yasumasa Iwatani

    Journal of virology   90 ( 2 )   1034 - 47   2016.1

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    DOI: 10.1128/JVI.02369-15

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  • Identification and characterization of the zosA gene involved in copper uptake in Bacillus subtilis 168. Reviewed International journal

    Takahiro Fukuhara, Kazuo Kobayashi, Yousuke Kanayama, Shu-ichi Enomoto, Taeko Kondo, Naoki Tsunekawa, Michiko Nemoto, Naotake Ogasawara, Kenji Inagaki, Takashi Tamura

    Bioscience, biotechnology, and biochemistry   80 ( 3 )   600 - 9   2016

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    DOI: 10.1080/09168451.2015.1107462

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  • Draft Genome Sequence of Streptomyces incarnatus NRRL8089, which Produces the Nucleoside Antibiotic Sinefungin. Reviewed International journal

    Kenshiro Oshima, Masahira Hattori, Hitomi Shimizu, Koji Fukuda, Michiko Nemoto, Kenji Inagaki, Takashi Tamura

    Genome announcements   3 ( 4 )   2015.7

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    DOI: 10.1128/genomeA.00715-15

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  • Oil accumulation by the oleaginous diatom Fistulifera solaris as revealed by the genome and transcriptome. Reviewed International journal

    Tsuyoshi Tanaka, Yoshiaki Maeda, Alaguraj Veluchamy, Michihiro Tanaka, Heni Abida, Eric Maréchal, Chris Bowler, Masaki Muto, Yoshihiko Sunaga, Masayoshi Tanaka, Tomoko Yoshino, Takeaki Taniguchi, Yorikane Fukuda, Michiko Nemoto, Mitsufumi Matsumoto, Pui Shan Wong, Sachiyo Aburatani, Wataru Fujibuchi

    The Plant cell   27 ( 1 )   162 - 76   2015.1

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    DOI: 10.1105/tpc.114.135194

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  • Morphological and molecular phylogenetic analysis of the high triglyceride-producing marine diatom, Fistulifera solaris sp nov (Bacillariophyceae) Reviewed

    Mitsufumi Matsumoto, Shigeki Mayama, Michiko Nemoto, Yorikane Fukuda, Masaki Muto, Tomoko Yoshino, Tadashi Matsunaga, Tsuyoshi Tanaka

    PHYCOLOGICAL RESEARCH   62 ( 4 )   257 - 268   2014.10

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    DOI: 10.1111/pre.12066

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  • Identification of a frustule-associated protein of the marine pennate diatom Fistulifera sp. strain JPCC DA0580. Reviewed International journal

    Michiko Nemoto, Yoshiaki Maeda, Masaki Muto, Masayoshi Tanaka, Tomoko Yoshino, Shigeki Mayama, Tsuyoshi Tanaka

    Marine genomics   16   39 - 44   2014.8

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    DOI: 10.1016/j.margen.2014.01.006

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  • 2030年への挑戦"藻類を燃料に

    田中剛, 根本 理子, 吉野知子

    太陽エネルギー   39   27 - 35   2014.1

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  • Proteomics analysis of oil body-associated proteins in the oleaginous diatom. Reviewed International journal

    Daisuke Nojima, Tomoko Yoshino, Yoshiaki Maeda, Masayoshi Tanaka, Michiko Nemoto, Tsuyoshi Tanaka

    Journal of proteome research   12 ( 11 )   5293 - 301   2013.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/pr4004085

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  • A process design and productivity evaluation for oil production by indoor mass cultivation of a marine diatom, Fistulifera sp. JPCC DA0580. Reviewed International journal

    Akira Satoh, Kyonosuke Ichii, Mitsufumi Matsumoto, Chihiro Kubota, Michiko Nemoto, Masayoshi Tanaka, Tomoko Yoshino, Tadashi Matsunaga, Tsuyoshi Tanaka

    Bioresource technology   137   132 - 8   2013.6

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    DOI: 10.1016/j.biortech.2013.03.087

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  • Phase Transformations and Structural Developments in the Radular Teeth of Cryptochiton Stelleri Reviewed

    Qianqian Wang, Michiko Nemoto, Dongsheng Li, James C. Weaver, Brian Weden, John Stegemeier, Krassimir N. Bozhilov, Leslie R. Wood, Garrett W. Milliron, Christopher S. Kim, Elaine DiMasi, David Kisailus

    ADVANCED FUNCTIONAL MATERIALS   23 ( 23 )   2908 - 2917   2013.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/adfm.201202894

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  • Molecular Bioengineering of Magnetosomes for Biotechnological Applications Reviewed

    Atsushi Arakaki, Michiko Nemoto, Tadashi Matsunaga

    Coordination Chemistry in Protein Cages: Principles, Design, and Applications   241 - 271   2013.4

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    Language:English   Publishing type:Part of collection (book)   Publisher:John Wiley and Sons  

    DOI: 10.1002/9781118571811.ch10

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  • Establishment of a genetic transformation system for the marine pennate diatom Fistulifera sp. strain JPCC DA0580--a high triglyceride producer. Reviewed International journal

    Masaki Muto, Yorikane Fukuda, Michiko Nemoto, Tomoko Yoshino, Tadashi Matsunaga, Tsuyoshi Tanaka

    Marine biotechnology (New York, N.Y.)   15 ( 1 )   48 - 55   2013.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10126-012-9457-0

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  • Proteomic analysis from the mineralized radular teeth of the giant Pacific chiton, Cryptochiton stelleri (Mollusca). Reviewed International journal

    Michiko Nemoto, Qianqian Wang, Dongsheng Li, Songqin Pan, Tadashi Matsunaga, David Kisailus

    Proteomics   12 ( 18 )   2890 - 4   2012.9

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    DOI: 10.1002/pmic.201100473

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  • Assessment of the anti-biofouling potentials of a copper iodide-doped nylon mesh. Reviewed International journal

    Tetsuya Sato, Yoshie Fujimori, Tsuruo Nakayama, Yasuo Gotoh, Yoshihiko Sunaga, Michiko Nemoto, Tadashi Matsunaga, Tsuyoshi Tanaka

    Applied microbiology and biotechnology   95 ( 4 )   1043 - 50   2012.8

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    DOI: 10.1007/s00253-011-3720-6

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  • Investigation of the antiviral properties of copper iodide nanoparticles against feline calicivirus. Reviewed

    Nozomi Shionoiri, Tetsuya Sato, Yoshie Fujimori, Tsuruo Nakayama, Michiko Nemoto, Tadashi Matsunaga, Tsuyoshi Tanaka

    Journal of bioscience and bioengineering   113 ( 5 )   580 - 6   2012.5

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    DOI: 10.1016/j.jbiosc.2011.12.006

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  • Prevention of marine biofouling on nylon mesh doped with silver iodide Reviewed

    Tetsuya Sato, Yoshie Fujimori, Tsuruo Nakayama, Yasuo Gotoh, Michiko Nemoto, Tadashi Matsunaga, Tsuyoshi Tanaka

    COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS   396   41 - 45   2012.2

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    DOI: 10.1016/j.colsurfa.2011.12.037

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  • 次世代液体バイオ燃料開発に向けた海洋生物資源の活用

    田中剛, 根本理子, 松永是

    ケミカルエンジニアリング   56 ( 9 )   713 - 718   2011.9

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  • Proteomic analysis of irregular, bullet-shaped magnetosomes in the sulphate-reducing magnetotactic bacterium Desulfovibrio magneticus RS-1. Reviewed International journal

    Tadashi Matsunaga, Michiko Nemoto, Atsushi Arakari, Masayoshi Tanaka

    Proteomics   9 ( 12 )   3341 - 52   2009.6

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    DOI: 10.1002/pmic.200800881

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  • Formation of magnetite by bacteria and its application. Reviewed International journal

    Atsushi Arakaki, Hidekazu Nakazawa, Michiko Nemoto, Tetsushi Mori, Tadashi Matsunaga

    Journal of the Royal Society, Interface   5 ( 26 )   977 - 99   2008.9

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    DOI: 10.1098/rsif.2008.0170

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Books

  • 化学と生物 <解説> オミクス解析に基づく生体鉱物形成関連タンパク質の同定

    根本理子( Role: Sole author)

    2023.9 

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  • 貝の疑問50

    日本貝類学会( Role: Contributor)

    成山堂書店  2023.4  ( ISBN:9784425984213

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  • A comparative gene analysis reveals a diatom-specific SET domain protein family

    根本理子

    2021 

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  • Magnetite biomineralization in radular teeth of chiton

    根本理子, KISAILUS David

    2020 

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  • Biological Magnetic Materials and Applications

    David Kisailus, Michiko Nemoto( Role: Contributor)

    2018.6 

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  • 化学と生物 <今日の話題> ヒザラガイの磁鉄鉱形成メカニズム

    根本 理子

    日本農芸化学会  2017.10 

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  • エリートHIVコントローラーの謎(バイオミディア)

    根本,理子

    日本生物工学会  2014.4 

  • Coordination Chemistry in Protein Cages: Principles, Design, and Applications

    Arakaki, A, Nemoto, M, Matsunaga, T( Role: Contributor ,  Molecular Bioengineering of Magnetosomes for Biotechnological Applications)

    2013.4 

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  • 2030 年への挑戦 “藻類を燃料に”

    田中剛, 根本理子, 吉野知子( Role: Joint author)

    一般社団法人日本太陽エネルギー学会  2013 

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  • バイオサイエンス 藻類から得られるバイオ燃料の可能性と今後の課題

    田中 剛, 根本 理子

    エヌ・ティー・エス  2012.3 

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  • 次世代液体バイオ燃料開発に向けた海洋生物資源の活用

    田中剛, 根本理子, 松永是( Role: Joint author)

    化学工業社  2011.9 

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  • マリンメタゲノムの有効利用

    新垣篤史, 根本理子, 松永是( Role: Contributor ,  磁性細菌のゲノム情報に基づいた機能性ナノ磁性材料の開発)

    シーエムシー出版  2009.7 

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MISC

  • 国内のHIV-2精査検体を用いた、HIV診断におけるGeenius HIV1/2 Confirmatory Assayの有用性についての検討

    重見 麗, 山村 喜美, 松田 昌和, 岡崎 玲子, 久保田 舞, 齋藤 誠司, 柳澤 邦雄, 柳 富子, 伊部 史朗, 根本 理子, 前島 雅美, 助川 明香, 今橋 真弓, 杉浦 亙, 岩谷 靖雅, 蜂谷 敦子, 横幕 能行

    日本エイズ学会誌   22 ( 4 )   518 - 518   2020.11

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  • 核酸系抗生物質シネフンギンの動物ウイルスに対する抗ウイルス活性評価

    黒田雄大, 根本理子, 稲垣賢二, 田村隆, 前田健, 前田健

    日本獣医学会学術集会講演要旨集   162nd   2019

  • 抗HIV療法における核酸系逆転写酵素阻害剤の腸内および口腔細菌叢への影響

    大出裕高, 今橋真弓, 今橋真弓, 小林歩美, 根本理子, 松田昌和, 羽柴知恵子, 羽柴知恵子, 重見麗, 岡崎玲子, 蜂谷敦子, 今村淳治, 今村淳治, 中畑征史, 中畑征史, 小暮あゆみ, 小暮あゆみ, 横幕能行, 横幕能行, 岩谷靖雅, 岩谷靖雅

    国立病院総合医学会(Web)   73rd   2019

  • [NiFeSe]型ヒドロゲナーゼのOne-Step精製を目的としたゲノム改変

    小沼瞳, 山神将大, 袴塚響, 田嶋智之, 高口豊, 根本理子, 稲垣賢二, 田村隆

    日本農芸化学会西日本支部大会およびシンポジウム講演要旨集   2019   2019

  • 放線菌Streptomyces sp.590由来の抗腫瘍性酵素L‐メチオニン脱炭酸酵素の遺伝子クローニング,組換え発現,均一精製および性質検討

    林将也, 岡田茜, 山本久美子, 奥河内知美, 日下知香, 工藤大蔵, 根本理子, 稲垣純子, 広瀬侑, 岡島俊英, 田村隆, 左右田健次, 稲垣賢二

    ビタミン   92 ( 3 )   113‐116   2018.3

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  • L-メチオニン、L-ホモシステイン新規定量法へのL-メチオニン脱炭酸酵素の活用

    林 将也, 大川 敦司, 半田 暖尚, 根本 理子, 稲垣 純子, 菊池 可菜子, 木村 隆, 田村 隆, 稲垣 賢二

    ビタミン   91 ( 4 )   286 - 286   2017.4

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  • 海洋性細菌由来の新規キノン含有グリシンオキシダーゼ −組換え発現と性質検討−

    溝端佐津紀, 根本理子, 田村隆, 稲垣賢二

    2016年度ビタミンB研究委員会報告書   147 - 148   2017.2

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  • 抗HIV療法における核酸系逆転写酵素阻害剤の腸内細菌叢への影響に関する研究

    大出裕高, 井上歩美, 根本理子, 松田昌和, 今橋真弓, 羽柴知恵子, 羽柴知恵子, 重見麗, 岡崎玲子, 蜂谷敦子, 蜂谷敦子, 今村淳治, 今村淳治, 今村淳治, 中畑征史, 中畑征史, 中畑征史, 小暮あゆみ, 小暮あゆみ, 小暮あゆみ, 横幕能行, 横幕能行, 横幕能行, 岩谷靖雅, 岩谷靖雅, 岩谷靖雅

    日本エイズ学会誌   18 ( 4 )   2016

  • 国内におけるHIV-2感染疑義症例に関する精査解析

    前島雅美, 伊部史朗, 根本理子, 今橋真弓, 伊部史朗, 根本理子, 今橋真弓, 今村淳治, 蜂谷敦子, 松田昌和, 重見麗, 岡崎玲子, 杉浦亙, 杉浦亙, 横幕能行, 岩谷靖雅, 岩谷靖雅

    日本エイズ学会誌   18 ( 4 )   2016

  • Rhodococcus sp.AIU Z‐35‐1由来L‐アミノ酸酸化酵素―組換え酵素の精製及び性質―

    村上佳穂, 橋本義輝, 小林達彦, 山田美和, 磯部公安, 根本理子, 田村隆, 稲垣賢二

    日本生物工学会大会講演要旨集   67th   275 - 275   2015.9

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  • 2P-184 Identification of [NiFeSe]-hydrogenases from sulfate reducing bacteria using ICP-MS

    Mishima Ayaka, Imoto Satoshi, Morikawa Daichi, Nemoto Michiko, Inagaki Kenji, Tamura Takashi

    67   220 - 220   2015

  • 3P-026 In vitro SPS assay using Thermus thermophiles HB8 PPDK

    Asano Kaori, Tobe Ryuta, Mihara Hisaaki, Nemoto Michiko, Inagaki Kenji, Tamura Takashi

    67   277 - 277   2015

  • 安全かつ効果的な抗HIV療法開発のための研究 抗HIV薬の耐性メカニズムの研究

    SUGIURA WATARU, MATSUOKA KAZUHIRO, NEMOTO MICHIKO

    安全かつ効果的な抗HIV療法開発のための研究 平成25年度総括・分担研究報告書   16 - 21   2014

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  • 3P-012 Identification of novel frustule proteins from a diatom Fistulifera sp. through in silico screening

    Maeda Yoshiaki, Nemoto Michiko, Yoshino Tomoko, Tanaka Tsuyoshi

    65   191 - 191   2013

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  • 本邦におけるHIV-2感染疑い症例の実情と問題点

    根本理子, 伊部史朗, 今橋真弓, 今橋真弓, 今村淳治, 岩谷靖雅, 岩谷靖雅, 横幕能行, 味澤篤, 杉浦亙, 杉浦亙

    日本エイズ学会誌   15 ( 4 )   2013

  • RNA‐seqに基づく海洋珪藻Fistulifera sp.solaris株のオイル蓄積機構の解析

    根本理子, 須永吉彦, 武藤正記, 松本光史, 田中祐圭, 吉野知子, 新垣篤史, 松永是, 田中剛

    日本化学会講演予稿集   92nd ( 3 )   764   2012.3

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  • 2Ia08 Development of oil body separation procedure and analysis of the oil body associated proteins from marine diatom Fistulifera sp. strain JPCC DA0580

    Nojima Daisuke, Nemoto Michiko, Yoshino Tomoko, Matsunaga Tadashi, Tanaka Tsuyoshi

    64   81 - 81   2012

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  • 2Aa04 Proteome analysis of the oil body of marine diatom Fistulifera sp. strain JPCC DAO580

    NOJIMA Daisuke, NEMOTO Michiko, YOSHINO Tomoko, MATSUNAGA Tadashi, TANAKA Tsuyoshi

    63   110 - 110   2011

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  • 2Fp11 Control of bacterial magnetite morphology by regulating expression of mms7 gene in magnetotactic bacteria

    YAMAGISHI Ayana, FUKUYO Ayumi, NEMOTO Michiko, ARAKAKI Atsushi, MATSUNAGA Tadashi

    63   155 - 155   2011

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  • マグネトソーム膜局在性カチオントランスポーターの鉄イオン輸送活性の評価

    陳吉子, 根本理子, 田中祐圭, 新垣篤史, 松永是

    マリンバイオテクノロジー学会大会講演要旨集   12th   114   2009.5

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  • Investigation of the shape control factor of bullet-shaped nano-magnetic crystals in sulfate reducing magnetotactic bacterium, Desulfovibrio magneticus RS-1

    NEMOTO MICHIKO, ARAKAKI ATSUSHI, TANAKA MASAYOSHI, MATSUNAGA TADASHI

    日本化学会講演予稿集   89th ( 2 )   1256   2009.3

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  • 3Fa10 Proteome analysis of irregular shaped magnetosomes in Desulfovibrio magneticus strain RS-1

    NEMOTO Michiko, ARAKAKI Atsushi, TANAKA Masayoshi, NAKAZAWA Hidekazu, JIN-NO Koji, YASHIRO Isao, MATSUNAGA Tadashi

    日本生物工学会大会講演要旨集   20   2008.7

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  • 硫酸還元磁性細菌Desulfovibrio magneticus RS‐1の生成するマグネトソームのプロテオーム解析

    根本理子, 新垣篤史, 田中祐圭, 松永是

    生化学   3P-0137   2007

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  • 硫酸還元磁性細菌Desulfovibrio magneticus RS‐1のバイオマグネタイトに強固に吸着するタンパク質の解析

    根本理子, 新垣篤史, 田中祐圭, 中澤秀和, 神野浩二, 矢代勲, 田中剛, 竹山春子, 松永是

    日本化学会バイオテクノロジー部会シンポジウム講演要旨集   9th   194   2006.9

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  • 2D11-3 Proteome analysis of magnetosome membrane in Desulfovibrio magneticus strain RS-1

    NEMOTO Michiko, ARAKAKI Atsushi, TANAKA Masayoshi, JIN-NO Kouji, YASHIRO Isao, NAKAZAWA Hidekazu, TAKEYAMA Haruko, MATSUNAGA Tadashi

    17   131 - 131   2005.9

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Presentations

  • 珪藻のシリカ被殻形成関連遺伝子の解析 Invited

    日本農芸化学会2025年度大会シンポジウム  2025.3.6 

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  • 鉄の歯をもつ貝:硬組織形成の新たなメカニズム

    日本農芸化学会2025年度大会シンポジウム  2025.3.5 

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  • ヒザラガイの鉄濃縮・沈着関連タンパク質の解析 Invited

    バイオミネラリゼーションセミナー(オンライン)  2024.10.23 

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  • 驚異的な鉄代謝能力を持つヒザラガイの鉄濃縮・沈着メカニズムの解析 Invited

    根本理子

    日本農芸化学会2024年大会  2024.3.25 

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  • ヒザラガイにおける鉄濃縮・沈着メカニズムの解析 Invited

    根本理子

    第65回日本植物生理学会年会  2024.3.19 

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  • ヒザラガイによる鉄濃縮・沈着機構の解析 Invited

    根本理子

    第47回日本鉄バイオサイエンス学会学術集会  2023.9.3 

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  • 生体鉱物形成に関わるタンパク質に関する研究 Invited

    根本理子

    農芸化学会中四国支部第64回支部講演会  2023.1.21 

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  • ヒザラガイ歯舌の磁鉄鉱形成関連タンパク質の同定 Invited

    根本理子

    動物学会 岡山県例会企画セミナー  2022.12.2 

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  • ヒザラガイの磁鉄鉱歯形成関連タンパク質の同定 Invited

    根本理子

    第33回日本微量元素学会学術集会  2022.9.9 

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  • Identification of Proteins Involved in Chiton Tooth Biomineralization by RNA-Seq-Based Analyses Invited

    Michiko Nemoto

    Gordon Research Conference Biomineralization  2022.8.16 

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  • Identification of proteins regulating silica biomineralization in diatoms

    2021.9.30 

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  • Genomic-based identification of proteins regulating biomineral formation Invited

    Michiko Nemoto

    The 22nd American Conference on Crystal Growth and Epitaxy  2021.8.3 

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  • 珪藻種間の遺伝子比較解析に基づく シリカ被殻形成関連タンパク質の同定 Invited

    根本理子

    日本珪藻学会 第42 回大会  2021.6.12 

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  • Comparative Gene Analysis Focused on Silica Cell Wall Formation:Identification of Diatom-Specific SET Domain Protein Methyltransferases Invited

    2021.5.15 

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  • Identification and comparative analysis of silica cell wall-associated proteins in diatoms Invited

    Michiko Nemoto

    MBSJ2020 Online  2020.12.4 

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  • RNA-seqを利用したバイオミネラリゼーション機構の解析 Invited

    日本農芸化学会中四国支部 第30回若手シンポジウム  2019.10 

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  • 生体鉱物の形成に関わるタンパク質の探索 Invited

    根本 理子

    日本農芸化学会中四国支部 第29回若手シンポジウム(第 11 回農芸化学の未来開拓セミナー)  2019.5 

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  • ヒザラガイ歯舌の磁鉄鉱形成メカニズム Invited

    根本 理子

    第13回バイオミネラリゼーションワークショップ  2018.11 

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  • Application of genomics and proteomics to biomineralization research Invited International conference

    根本 理子

    International Workshop for Interplay between Nanocarbon, Supramolecule, and Biochemistry  2016.3 

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Awards

  • 2021年度農芸化学若手女性研究者賞

    2022.3   日本農芸化学会   生体鉱物形成に関わるタンパク質に関する研究

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  • 令和2年度マリンバイオテクノロジー論文賞

    2021.5   マリンバイオテクノロジー学会  

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Research Projects

  • がん細胞内過剰鉄を酸化鉄に変換する革新的技術の開発

    2022.04 - 2025.03

    科学技術振興機構  創発的研究支援事業 

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  • ヒザラガイの磁鉄鉱歯特異的な鉄酸化酵素の機能解明

    Grant number:22H04812  2022.04 - 2024.03

    日本学術振興会  科学研究費助成事業 新学術領域研究(研究領域提案型)  新学術領域研究(研究領域提案型)

    根本 理子

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    Grant amount:\5720000 ( Direct expense: \4400000 、 Indirect expense:\1320000 )

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  • ヒザラガイの磁鉄鉱歯特異的な歯舌マトリックスタンパク質の機能解明

    Grant number:21K05781  2021.04 - 2025.03

    日本学術振興会  科学研究費助成事業 基盤研究(C)  基盤研究(C)

    根本 理子, 守屋 央朗

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    Grant amount:\4290000 ( Direct expense: \3300000 、 Indirect expense:\990000 )

    本研究では、ヒザラガイの歯冠部特異的タンパク質である歯舌マトリックスタンパク質1(RTMP1)について、遺伝子ノックダウンおよび組換えタンパク質を用いた機能解析を行ない、歯冠部への酸化鉄沈着におけるRTMP1の役割を明らかにすることを目的とする。
    2021年度は、まず、オオバンヒザラガイの遺伝子ノックダウンシステムの確立を目指して実験を行った。実験には、北海道大学の厚岸臨海実験所のご協力の下、採取したオオバンヒザラガイ個体を用いた。使用する個体重量、飼育条件、dsRNA注入量およびノックダウン後、表現型解析を行なうまでの時間を検討し、各条件について最適化した。その結果、RTMP1遺伝子をターゲットとするdsRNAを注入した個体において、陰性対照と比較して有意にRTMP1遺伝子発現量が低下することが確認された。顕微鏡観察から、遺伝子発現量が低下した個体において、歯の沈着鉄量の減少を示唆する結果が得られた。
    また、in vitro機能解析に向けて、酵母でRTMP1を組換え発現させ、その精製を行った。RTMP1遺伝子全長及びシグナル配列をコードする領域を除いたRTMP1遺伝子(RTMP1-delta-ss)をGST融合発現用ベクターpEG(KT)に組み込み酵母に発現させた。研究分担者の守屋とともに、プロモーター、可溶化タグ、コドンの最適化による発現量の増加を試みた結果、RTMP1-delta-ssの発現を確認することができた。また、発現が確認されたRTMP1-delta-ssについて、グルタチオンビーズを用いた粗精製に成功した。

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  • ヒザラガイ類のトランスクリプトーム比較に基づく生物磁鉄鉱形成の分子基盤解明

    2021 - 2022

    日本農芸化学会  第1回農芸化学若手女性研究者チャレンジ研究助成 

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  • パルマ藻を用いて解明するシリカの細胞壁の設計図

    Grant number:20K06725  2020.04 - 2023.03

    日本学術振興会  科学研究費助成事業 基盤研究(C)  基盤研究(C)

    吉川 伸哉, 根本 理子

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    Grant amount:\4290000 ( Direct expense: \3300000 、 Indirect expense:\990000 )

    パルマ藻とケイ藻の共通の特徴は、シリカを主成分とする細胞壁を持つことである。これまでのケイ藻を用いた研究で、シリカの細胞壁の形成に関わるタンパク質は複数発見されているが、ケイ藻では、細胞壁を持たない細胞を人為的に作ることが困難であるため、それらのタンパク質の細胞壁形成時における細胞内での役割は十分に解明されていない。本研究では、ケイ藻とは異なり任意に細胞壁合成を制御することが可能なパルマ藻を用いて、シリカの細胞壁の形成機構を明らかにするため、トランスクリプトーム解析 (RNA-seq解析)・生化学的解析・ゲノム解析により細胞壁形成に関わる遺伝子を同定することを目的とする。ケイ藻のシリカの細胞壁形成では、細胞壁に共存するタンパク質やポリアミンなどの有機基質がシリカ重合に関与することが知られているが、ケイ藻と近縁なパルマ藻においては、シリカの細胞壁に共存するタンパク質は見つかっていない。R3年度は、生化学的な手法により細胞壁形成に関わるタンパク質を探索するため、パルマ藻Triparma laevis longispina細胞からアセトン、SDS処理により細胞壁画分を得た後に、フッ化水素処理によりシリカを溶解し細胞壁に含まれている有機成分を得た。得られた有機成分をSDS-PAGEで分離し、主要なバンドをプロテアーゼ処理後、液体クロマトグラフ質量分析(LC-MS/MS)に供した。LC-MS/MSで得られたペプチド配列とT. laevis longispinaのゲノム情報から細胞壁に含まれるタンパク質をコードすると予測される2つの遺伝子を同定した。

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  • ヒザラガイの磁鉄鉱歯特異的タンパク質の機能解明

    2019 - 2020

    日揮・実吉奨学会研究助成金 

    根本理子

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    Authorship:Principal investigator 

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  • 異分野連携によるバイオミネラリゼーション機構の解明とその応用

    2019

    岡山大学  令和元年度岡山大学次世代研究育成グループ 

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  • 珪藻のシリカ被殻形成関連タンパク質の動態解析に基づく被殻形成機構の解明

    2018.04 - 2021.03

    文部科学省  基盤研究(C) 

    根本 理子

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    Authorship:Principal investigator  Grant type:Competitive

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  • ヒザラガイ歯舌の磁鉄鉱形成に関わるタンパク質の同定及び機能解明

    2018 - 2019

    加藤記念バイオサイエンス振興財団加藤記念研究助成  競争的資金

    根本理子

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  • 地球規模の炭素循環に関わる珪藻のシリコン貯蔵機構の解明

    2017 - 2018

    八雲環境科学振興財団 環境研究助成 

    根本理子

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    Authorship:Principal investigator 

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  • 環境負荷の小さいセラミックス微細加工技術の開発を指向したバイオシリカ構造制御分子の同定

    2017

    岡山工学振興会  岡山工学振興会奨励研究助成 

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  • 非モデル珪藻種の比較解析に基づくバイオシリカナノパターン形成機構の解明

    2016

    ウエスコ学術振興財団研究費助成 

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  • シリカ沈着小胞の解析に基づく生物によるシリカナノパターニング機構の解明

    2015 - 2016

    旭硝子財団 研究奨励 

    根本理子

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    Authorship:Principal investigator 

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  • ナノ微細構造をもつ珪藻殻を利用した高出力バイオ燃料電池の作製

    2015 - 2016

    新世代研究所 2015年度研究助成 

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  • エイズ発症者から分離された新規HIV-2が宿主防御機構から逃避する分子機序の解明

    2014.04 - 2016.03

    文部科学省  若手研究(B) 

    根本 理子

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    Authorship:Principal investigator  Grant type:Competitive

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Class subject in charge

  • Analytical Chemistry 1 (2024academic year) 1st semester  - 月1,月2

  • Topics in Development of Microbial Function (2024academic year) Prophase  - 水3~4

  • Seminar in Applied Enzyme Chemistry (2024academic year) Prophase  - その他

  • Seminar in Applied Enzyme Chemistry (2024academic year) Late  - その他

  • Seminar in Applied Enzyme Chemistry (2024academic year) Late  - その他

  • Seminar in Applied Enzyme Chemistry (2024academic year) Prophase  - その他

  • Seminar in Food Biochemistry (2024academic year) Year-round  - その他

  • Current Topics in Applied Enzyme Chemistry (2024academic year) Prophase  - その他

  • Applied Microbiology 3 (2024academic year) 1st and 2nd semester  - 水1,水2

  • Advanced Study (2024academic year) Other  - その他

  • Advanced Study (2024academic year) Other  - その他

  • Analytical Chemistry 1 (2023academic year) 1st semester  - 月1,月2

  • Topics in Development of Microbial Function (2023academic year) Prophase  - 水3,水4

  • Topics in Development of Microbial Function (2023academic year) Prophase  - 水3~4

  • Seminar in Applied Enzyme Chemistry (2023academic year) Prophase  - その他

  • Seminar in Applied Enzyme Chemistry (2023academic year) Late  - その他

  • Seminar in Applied Enzyme Chemistry (2023academic year) Late  - その他

  • Seminar in Applied Enzyme Chemistry (2023academic year) Late  - その他

  • Seminar in Applied Enzyme Chemistry (2023academic year) Prophase  - その他

  • Seminar in Applied Enzyme Chemistry (2023academic year) Prophase  - その他

  • Seminar in Food Biochemistry (2023academic year) Year-round  - その他

  • Current Topics in Applied Enzyme Chemistry (2023academic year) Prophase  - その他

  • Current Topics in Applied Enzyme Chemistry (2023academic year) Prophase  - その他

  • Applied Microbiology 3 (2023academic year) 1st and 2nd semester  - 水1,水2

  • Advanced Study (2023academic year) Other  - その他

  • Advanced Study (2023academic year) Other  - その他

  • Specific Research of Bioresources Science (2023academic year) Year-round  - その他

  • Seminar in Applied Enzyme Chemistry (2022academic year) Prophase  - その他

  • Seminar in Applied Enzyme Chemistry (2022academic year) Late  - その他

  • Seminar in Applied Enzyme Chemistry (2022academic year) Late  - その他

  • Seminar in Applied Enzyme Chemistry (2022academic year) Prophase  - その他

  • Current Topics in Applied Enzyme Chemistry (2022academic year) Prophase  - その他

  • Biochemistry and Bioengineering of Useful Enzymes (2022academic year) Prophase  - 火3,火4

  • Specific Research of Bioresources Science (2022academic year) Year-round  - その他

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Social Activities

  • 電子顕微鏡を使って生物を見てみよう

    Role(s):Planner, Demonstrator

    岡山大学ダイバーシティ推進本部男女共同参画室  2019年度おかやまサイエンス・トーク&トライアル  2019.8

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    Type:Seminar, workshop

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  • 電子顕微鏡を使って生物を見てみよう

    Role(s):Planner, Demonstrator

    岡山大学ダイバーシティ推進本部男女共同参画室  平成30年度 おかやまサイエンストーク&トライアル  2018.8

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    Type:Seminar, workshop

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  • ガラスの細胞壁を持つ藻類 “珪藻” を学ぶ

    Role(s):Planner, Demonstrator

    岡山大学  科学先取りグローバルキャンパス岡山(GSCO)  2017.12

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    Type:Seminar, workshop

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  • 電子顕微鏡を使って生物を見てみよう

    Role(s):Planner, Demonstrator

    岡山大学ダイバーシティ推進本部男女共同参画室  平成29年度おかやまサイエンス・トライアル  2017.8

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  • 遺伝子・タンパク質の解析を通して生物による鉱物形成メカニズムを明らかにする

    Role(s):Planner, Demonstrator

    岡山大学ダイバーシティ推進本部男女共同参画室  平成28年度第3回おかやまサイエンス・トーク  2016.7

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    Type:Visiting lecture

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  • 生物のつくる磁石

    Role(s):Planner, Demonstrator

    岡山大学ダイバーシティ推進本部男女共同参画室  平成27年度 第1回おかやまサイエンス・トーク  2015.7

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Media Coverage

  • 模造ダイヤより頑丈な歯、ありふれた貝が磁鉄鉱作る仕組み解明 Newspaper, magazine

    朝日新聞  2025.8

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  • 磁鉄鉱で歯、貝の仕組み解明 Newspaper, magazine

    日刊工業新聞  2025.8

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  • 非常に硬い「磁鉄鉱の歯」を持つヒザラガイの生体内メカニズムを解明 Internet

    KSB瀬戸内海放送  2025.8

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  • 地球最強の歯を持つ貝 ヒザラガイ TV or radio program

    BSフジ  「ガリレオX」  2025.6

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  • 磁鉄鉱の合成 貝からヒント Newspaper, magazine

    毎日新聞  2019.5

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  • 磁鉄鉱作るヒザラガイ遺伝子特定 Newspaper, magazine

    山陽新聞  2019.5

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