Faculty Profiles - katsuyama eri

Papers - katsuyama eri

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脱毛から診断に至った高齢期発症の全身性エリテマトーデスの1例

岡野真理, 横山恵美, 川上佳夫, 森実真, 勝山恵理, 山口春佳

日本皮膚科学会雑誌 133 ( 8 ) 1892 - 1892 2023.7

今年も開催!!行列のできる診療所第3弾:脂質異常症難病ケーススタディ高安動脈炎が疑われたがPET-CTを契機に希少疾患であるシトステロール血症と判明した一例

中土井崇人, 勝山恵理, 松本和也, 廣瀬啓, 志田原健太, 縄稚翔一, 浅野洋介, 片山祐, 宮脇義亜, 勝山隆行, 楢崎真理子, 松本佳則, 佐田憲映, 多田隼人, 和田淳

日本動脈硬化学会総会プログラム・抄録集 55回 130 - 130 2023.6

The Association of Grit With Burnout Components (Professional Efficacy, Exhaustion, and Cynicism) Among Academic Rheumatologists: The TRUMP2-SLE Study. International journal

Yoshia Miyawaki, Ken-Ei Sada, Kenta Shidahara, Shoichi Nawachi, Yosuke Asano, Yu Katayama, Keigo Hayashi, Eri Katsuyama, Takayuki Katsuyama, Mariko Takano-Narazaki, Yoshinori Matsumoto, Nao Oguro, Nobuyuki Yajima, Yuichi Ishikawa, Natsuki Sakurai, Chiharu Hidekawa, Ryusuke Yoshimi, Takanori Ichikawa, Dai Kishida, Yasuhiro Shimojima, Jun Wada, Noriaki Kurita

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 29 ( 6 ) 268 - 274 2023.5

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVES: There is a high prevalence of burnout among rheumatologists. Grit, which is defined as possessing perseverance and a passion to achieve long-term goals, is predictive of success in many professions; however, whether grit is associated with burnout remains unclear, especially among academic rheumatologists, who have multiple simultaneous responsibilities. Thus, the purpose of this study was to examine the associations between grit and self-reported burnout components-professional efficacy, exhaustion, and cynicism-in academic rheumatologists. METHODS: This cross-sectional study involved 51 rheumatologists from 5 university hospitals. The exposure was grit, measured using mean scores for the 8-item Short Grit Scale (range, 1-5 [5 = extremely high grit]). The outcome measures were mean scores for 3 burnout domains (exhaustion, professional efficacy, and cynicism; range, 1-6; measured using the 16-item Maslach Burnout Inventory-General Survey). General linear models were fitted with covariates (age, sex, job title [associate professor or higher vs lower], marital status, and having children). RESULTS: Overall, 51 physicians (median age, 45 years; interquartile range, 36-57; 76% men) were included. Burnout positivity was found in 68.6% of participants (n = 35/51; 95% confidence interval [CI], 54.1, 80.9). Higher grit was associated with higher professional efficacy (per 1-point increase; 0.51 point; 95% CI, 0.18, 0.84) but not with exhaustion or cynicism. Being male and having children were associated with lower exhaustion (-0.69; 95% CI, -1.28, -0.10; p = 0.02; and -0.85; 95% CI, -1.46, -0.24; p = 0.006). Lower job title (fellow or part-time lecturer) was associated with higher cynicism (0.90; 95% CI, 0.04, 1.75; p = 0.04). CONCLUSIONS: Grit is associated with higher professional efficacy among academic rheumatologists. To prevent burnout among staff, supervisors who manage academic rheumatologists should assess their staff's individual grit.

DOI： 10.1097/RHU.0000000000001989

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Amelioration of nephritis in receptor for advanced glycation end-products (RAGE)-deficient lupus-prone mice through neutrophil extracellular traps. International journal

Haruki Watanabe, Masataka Kubo, Akihiko Taniguchi, Yosuke Asano, Sumie Hiramatsu-Asano, Keiji Ohashi, Sonia Zeggar, Eri Katsuyama, Takayuki Katsuyama, Katsue Sunahori-Watanabe, Ken-Ei Sada, Yoshinori Matsumoto, Yasuhiko Yamamoto, Hiroshi Yamamoto, Myoungsun Son, Jun Wada

Clinical immunology (Orlando, Fla.) 250 109317 - 109317 2023.5

Language：English Publishing type：Research paper (scientific journal)

The receptor for advanced glycation end-products (RAGE) is a pattern recognition receptor that regulates inflammation, cell migration, and cell fate. Systemic lupus erythematosus (SLE) is a chronic multiorgan autoimmune disease. To understand the function of RAGE in SLE, we generated RAGE-deficient (Ager-/-) lupus-prone mice by backcrossing MRL/MpJ-Faslpr/J (MRL-lpr) mice with Ager-/- C57BL/6 mice. In 18-week-old Ager-/- MRL-lpr, the weights of the spleen and lymph nodes, as well as the frequency of CD3+CD4-CD8- cells, were significantly decreased. Ager-/- MRL-lpr mice had significantly reduced urine albumin/creatinine ratios and markedly improved renal pathological scores. Moreover, neutrophil infiltration and neutrophil extracellular trap formation in the glomerulus were significantly reduced in Ager-/- MRL-lpr. Our study is the first to reveal that RAGE can have a pathologic role in immune cells, particularly neutrophils and T cells, in inflammatory tissues and suggests that the inhibition of RAGE may be a potential therapeutic strategy for SLE.

DOI： 10.1016/j.clim.2023.109317

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プラスミノーゲン欠乏症に腸管型ベーチェット病を合併し広範な皮膚粘膜病変を発症した一例

中土井崇人, 勝山恵理, 寺嶋悠也, 松本和也, 廣瀬啓, 志田原健太, 縄稚翔一, 浅野洋介, 片山祐, 宮脇義亜, 勝山隆行, 楢崎真理子, 松本佳則, 佐田憲映, 大塚文男, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 67回 795 - 795 2023.3

中耳炎再燃を繰り返し,ANCA陰性であったがANCA関連血管炎性中耳炎(OMAAV)の診断に至った2例

志田原健太, 松本佳則, 寺嶋悠也, 廣瀬啓, 松本和也, 中土井崇人, 縄稚翔一, 浅野洋介, 片山祐, 宮脇義亜, 勝山恵理, 勝山隆行, 楢崎真理子, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 67回 790 - 790 2023.3

皮膚筋炎加療中に重篤なBordetella bronchiseptica肺炎,菌血症を呈した一例

寺嶋悠也, 片山祐, 松本和也, 廣瀬啓, 志田原健太, 中土井崇人, 縄稚翔一, 浅野洋介, 宮脇義亜, 勝山隆行, 勝山恵理, 楢崎真理子, 松本佳則, 佐田憲映, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 67回 852 - 852 2023.3

多発性筋炎・皮膚筋炎5:筋病変嚥下機能障害を伴う炎症性筋疾患,その臨床的特徴と予後についての検討

勝山隆行, 宮脇義亜, 寺嶋悠也, 中土井崇人, 松本和也, 廣瀬啓, 志田原健太, 縄稚翔一, 浅野洋介, 片山祐, 大橋敬司, 勝山惠理, 楢崎真理子, 松本佳則, 佐田憲映, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 67回 643 - 643 2023.3

難治性病態への挑戦免疫抑制療法が有効であった抗RNP抗体陽性の特発性肺動脈性肺高血圧症の一例

松本和也, 宮脇義亜, 勝山隆行, 中土井崇人, 志田原健太, 廣瀬啓, 縄稚翔一, 浅野洋介, 片山祐, 勝山恵理, 楢崎真理子, 松本佳則, 佐田憲映, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 67回 720 - 720 2023.3

SLE(ヒドロキシクロロキン・その他) SLE患者の心理的健康観の最小重要差と副腎皮質ステロイド量の検討多施設共同前向きコホート研究(Lupus registry of Nationwide institutions:LUNA)

宮脇義亜, 松本和也, 廣瀬啓, 志田原健太, 縄稚翔一, 中土井崇人, 浅野洋介, 片山祐, 勝山恵理, 勝山隆行, 楢崎真理子, 松本佳則, 佐田憲映, 柳井亮, 矢嶋宣幸, 高谷亜由子, 一瀬邦弘, 梶山浩, 西村啓佑, 木田節, 下島恭弘, 吉見竜介, 大野滋, 大西貴久, 佐藤秀三, 藤原道雄, 松尾祐介, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 67回 660 - 660 2023.3

高齢発症SLEの脱毛が著明に改善した1例

秋山万里子, 勝山恵理, 中土井崇人, 松本和也, 廣瀬啓, 志田原健太, 縄稚翔一, 浅野洋介, 片山祐, 宮脇義亜, 勝山隆行, 楢崎真理子, 松本佳則, 佐田憲映, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 67回 915 - 915 2023.3

COVID-19罹患後に発症した抗MDA5抗体陽性皮膚筋炎の一例

樋口朝涼香, 勝山隆行, 寺嶋悠也, 松本和也, 廣瀬啓, 志田原健太, 縄稚翔一, 中土井崇人, 浅野洋介, 片山祐, 宮脇義亜, 勝山恵理, 楢崎真理子, 松本佳則, 佐田憲映, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 67回 914 - 914 2023.3

全身性エリテマトーデス(SLE)治療中に下腿浮腫、下肢運動障害が出現したサイトメガロ(CMV)脳脊髄炎の一例

齋藤光希, 松本佳則, 寺嶋悠也, 松本和也, 廣瀬啓, 志田原健太, 縄稚翔一, 中土井崇人, 浅野洋介, 片山祐, 大橋敬司, 宮脇義亜, 勝山恵理, 勝山隆行, 楢崎真理子, 佐田憲映, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 67回 928 - 928 2023.3

インフリキシマブ投与中に内臓播種性帯状疱疹を発症した腸管ベーチェット病の1例

大久保茉柚, 片山祐, 寺嶋悠也, 志田原健太, 廣瀬啓, 松本和也, 中土井崇人, 縄稚翔一, 浅野洋介, 宮脇義亜, 勝山恵理, 勝山隆行, 楢崎真理子, 松本佳則, 佐田憲映, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 67回 916 - 916 2023.3

膵尾部腫瘤の切除後8年経過し,冠動脈周囲炎と心嚢液貯留を契機に診断されたIgG4関連疾患の1例

縄稚翔一, 勝山恵理, 寺嶋悠也, 廣瀬啓, 松本和也, 志田原健太, 中土井崇人, 浅野洋介, 片山祐, 宮脇義亜, 勝山隆行, 楢崎真理子, 松本佳則, 佐田憲映, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 67回 897 - 897 2023.3

再燃を繰り返しPET-CTで右冠動脈周囲B細胞性リンパ腫の診断に至った抗TIF1-γ抗体陽性皮膚筋炎の一例

廣瀬啓, 勝山隆行, 寺嶋悠也, 松本和也, 志田原健太, 中土井崇人, 縄稚翔一, 浅野洋介, 片山祐, 宮脇義亜, 勝山恵理, 楢崎真理子, 松本佳則, 佐田憲映, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 67回 888 - 888 2023.3

多発血管炎性肉芽腫症(GPA)に対してリツキシマブ投与中にカンピロバクター菌血症を発症した一例

川嶋帆乃, 縄稚翔一, 寺嶋悠也, 廣瀬啓, 松本和也, 志田原健太, 中土井崇人, 浅野洋介, 片山祐, 宮脇義亜, 勝山隆行, 勝山恵理, 楢崎真理子, 松本佳則, 佐田憲映, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 67回 914 - 914 2023.3

ベーチェット病様症状を呈したパルボウィルスB19感染症の一例

物部祥子, 松本佳則, 寺嶋悠也, 松本和也, 廣瀬啓, 志田原健太, 縄稚翔一, 中土井崇人, 浅野洋介, 片山祐, 大橋敬司, 宮脇義亜, 勝山恵理, 勝山隆行, 楢崎真理子, 佐田憲映, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 67回 914 - 914 2023.3

Association of alcohol consumption and fatigue in SLE: A cross-sectional study from Lupus Registry of Nationwide Institution (LUNA) cohort. International journal

Yu Katayama, Yoshia Miyawaki, Kenta Shidahara, Shoichi Nawachi, Yosuke Asano, Keiji Ohashi, Eri Katsuyama, Takayuki Katsuyama, Mariko Narazaki, Yoshinori Matsumoto, Ken-Ei Sada, Nobuyuki Yajima, Yasuhiro Shimojima, Ryusuke Yoshimi, Kunihiro Ichinose, Hiroshi Kajiyama, Michio Fujiwara, Shuzo Sato, Jun Wada

Lupus 32 ( 4 ) 9612033231159471 - 9612033231159471 2023.2

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: Fatigue is one of the most common complaints and is a potentially modifiable issue in systemic lupus erythematosus (SLE). Studies suggest that alcohol consumption has a protective effect against the development of SLE; however, an association between alcohol consumption and fatigue in patients with SLE has not been studied. Here, we assessed whether alcohol consumption was associated with fatigue using lupus patient-reported outcomes (LupusPRO). METHODS: This cross-sectional study, conducted between 2018 and 2019, included 534 patients (median age, 45 years; 87.3% female) from 10 institutions in Japan. The main exposure was alcohol consumption, which was defined as the frequency of drinking [<1 day/month (none group), ≤1 day/week (moderate group), and ≥2 days/week (frequent group)]. The outcome measure was the Pain Vitality domain score in LupusPRO. Multiple regression analysis was performed as the primary analysis after adjusting for confounding factors, such as age, sex, and damage. Subsequently, the same analysis was performed as a sensitivity analysis after multiple imputations (MIs) for missing data (n = 580). RESULTS: In total, 326 (61.0%) patients were categorized into the none group, 121 (22.7%) into the moderate group, and 87 (16.3%) into the frequent group. The frequent group was independently associated with less fatigue compared with none group [β = 5.98 (95% CI 0.19-11.76), p = 0.04], and the results did not substantially deviate after MI. CONCLUSIONS: Frequent drinking was associated with less fatigue, which highlights the need for further longitudinal studies focusing on drinking habits in patients with SLE.

DOI： 10.1177/09612033231159471

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A young female case of asymptomatic immune-mediated necrotizing myopathy: a potential diagnostic option of antibody testing for rhabdomyolysis. International journal

Ryo Sasaki, Taijun Yunoki, Yumiko Nakano, Yusuke Fukui, Mami Takemoto, Ryuta Morihara, Eri Katsuyama, Ichizo Nishino, Toru Yamashita

Neuromuscular disorders : NMD 33 ( 2 ) 183 - 186 2023.2

Language：English

Anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) immune-mediated necrotizing myopathy (IMNM) is a neuromuscular disorder that presents muscle weakness in proximal extremities and/or the trunk with an elevation of creatine kinase (CK). Young and asymptomatic anti-HMGCR IMNM patients are very rare and a treatment regimen has not been established. The present case, a 17-year-old woman without any muscular symptoms, only showed hyperCKemia that was detected by chance. After close examinations, including a muscle biopsy and antibody search, she was diagnosed as anti-HMGCR IMNM, and initial treatment with methotrexate and continuous intravenous immunoglobulin seemed to be effective. The present case is the unusually young asymptomatic case of anti-HMGCR IMNM. The diagnosis was successfully made, leading to the early introduction of a treatment. Given the course of this case, we believe that the preceding antibody testing is one of the diagnostic option for rhabdomyolysis.

DOI： 10.1016/j.nmd.2022.12.012

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