Faculty Profiles - katsuyama eri

Papers - katsuyama eri

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Dyspnea with Hemidiaphragm Elevation in a Patient with Giant Cell Arteritis: A Case Report

Yosuke Asano, Yoshinori Matsumoto, Natsuki Kubota, Yuya Terajima, Kazuya Matsumoto, Kenta Shidahara, Kei Hirose, Takato Nakadoi, Shoichi Nawachi, Yu Katayama, Yoshia Miyawaki, Eri Katsuyama, Takayuki Katsuyama, Mariko Takano-Narazaki, Ken-Ei Sada, Jun Wada

Internal Medicine 2025

Pericardial artery lymphoma in a patient with dermatomyositis: A case report. International journal

Kei Hirose, Takayuki Katsuyama, Natsuki Kubota, Yuya Terajima, Kazuya Matsumoto, Kenta Shidahara, Takato Nakadoi, Shoichi Nawachi, Yu Katayama, Yoshia Miyawaki, Eri Katsuyama, Mariko Narazaki-Takano, Yoshinori Matsumoto, Noboru Asada, Ken-Ei Sada, Jun Wada

Modern rheumatology case reports 2024.11

Language：English Publishing type：Research paper (scientific journal)

A woman in her 60s presented with erythema on both elbows, dyspnea on exertion, discomfort, and swelling of the left upper extremity, followed by swelling and myalgia of the right upper and lower extremities. She was diagnosed with anti-TIF1γ antibody-positive dermatomyositis with interstitial pneumonia. The initial screening tests for malignant diseases including contrast-enhanced CT, upper and lower endoscopy, and gynecological examination did not reveal any obvious abnormalities. The patient experienced two recurrent episodes of muscle weakness and dysphagia during treatment with intravenous glucocorticoids and cyclophosphamide. Five months after diagnosis, a bone marrow biopsy and positron emission tomography- computed tomography (PET-CT) scan revealed a coronary malignant lymphoma with suspected systemic metastasis. Although chemotherapy was initiated, the patient ultimately succumbed to alveolar hemorrhage. Coronary lymphoma is very rare and there has been no report of a cases associated with myositis. PET-CT may be useful for searching malignancy in anti-TIF1γ antibody-positive dermatomyositis cases of recurrent relapse.

DOI： 10.1093/mrcr/rxae065

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Association between discontinuity of care and patient trust in the usual rheumatologist among patients with systemic lupus erythematosus: a cross-sectional study

Yu Katayama, Yoshia Miyawaki, Kenta Shidahara, Shoichi Nawachi, Yosuke Asano, Eri Katsuyama, Takayuki Katsuyama, Mariko Takano-Narazaki, Yoshinori Matsumoto, Nao Oguro, Nobuyuki Yajima, Yuichi Ishikawa, Natsuki Sakurai, Chiharu Hidekawa, Ryusuke Yoshimi, Shigeru Ohno, Takanori Ichikawa, Dai Kishida, Yasuhiro Shimojima, Ken-ei Sada, Jun Wada, David H. Thom, Noriaki Kurita

Arthritis Research & Therapy 26 ( 1 ) 2024.11

CD38 in SLE CD4 T cells promotes Ca2+ flux and suppresses interleukin-2 production by enhancing the expression of GM2 on the surface membrane

Eri Katsuyama, Morgane Humbel, Abel Suarez-Fueyo, Abhigyan Satyam, Nobuya Yoshida, Vasileios C. Kyttaris, Maria G. Tsokos, George C. Tsokos

Nature Communications 15 ( 1 ) 2024.9

Expanded CD8+CD38+ T Cell Population in Patients With Systemic Lupus Erythematosus Is Linked to Increased Infection Rates: A Prospective Study. International journal

Jose Rubio, Morgane Humbel, Lama Mulki, Eri Katsuyama, Suzanne Krishfield, Julianne O'Connell, George C Tsokos, Vasileios Kyttaris

ACR open rheumatology 2024.8

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: One of the leading causes of morbidity and mortality among patients with systemic lupus erythematosus (SLE) is infections. The expression of the ectonucleotidase CD38 on the surface of CD8+ T cells has been linked to compromised cytotoxic function. The aim of this prospective study was to assess whether the presence of CD8+CD38+ in the peripheral blood of patients with SLE can serve as a biomarker for infectious complications. METHODS: A cohort of 80 patients with SLE were recruited over 18 months. The rate of clinically significant infections and presence of CD8+CD38+ T cells in the peripheral blood were monitored at each clinic visit. The patients were classified into high CD38+ and low CD38+ CD8+ T cells using flow cytometry and a previously established cutoff rate of 28.4%. RESULTS: A total of 20 infections were registered over the study period. We observed that the patients with an expanded CD8+CD38+ T cell population in the peripheral blood had a higher rate of recurrent infections and a higher likelihood of infection compared with patients with a low CD8+CD38+ T cell population. The levels of CD38 in CD8+ T cells remained stable over time in the studied subjects. CONCLUSION: High levels of CD8+CD38+ T cells in the peripheral blood of patients with SLE identify a subgroup prone to infections for whom proper clinical measures should be applied.

DOI： 10.1002/acr2.11725

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Discontinuity of care and trust in usual physician among patients with systemic lupus erythematosus

Katayama Yu, Miyawaki Yoshia, Shidahara Kenta, Nawachi Shoichi, Asano Yosuke, Katsuyama Eri, Katsuyama Takayuki, Takano-Narazaki Mariko, Matsumoto Yoshinori, Oguro Nao, Ishikawa Yuichi, Sakurai Natsuki, Hidekawa Chiharu, Ohno Shigeru, Ichikawa Takanori, Kishida Dai, Shimojima Yasuhiro, Sada Ken-ei, Wada Jun, Thom David, Kurita Noriaki† (†last author)

medRxiv 2024.03.13.24304255 2024.3

漿液性網膜剥離と蛋白漏出胃腸症を合併した全身性エリテマトーデスの一例

都明希, 勝山隆行, 久保田菜月, 寺嶋悠也, 松本和也, 廣瀬啓, 志田原健太, 縄稚翔一, 中土井崇人, 片山祐, 宮脇義亜, 勝山恵理, 楢崎真理子, 松本佳則, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 68回 914 - 914 2024.3

TAFRO症候群に緩徐進行1型糖尿病を合併した1例

喜舎場朝基, 片山祐, 久保田菜月, 寺嶋悠也, 松本和也, 廣瀬啓, 志田原健太, 縄稚翔一, 中土井崇人, 宮脇義亜, 勝山恵理, 勝山隆行, 楢崎真理子, 松本佳則, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 68回 914 - 914 2024.3

重症感染症を合併した難治性中小型血管炎に対してアバコパンとγグロブリン大量静注療法(IVIG)で寛解導入に至った1例

小松原悠, 松本佳則, 久保田菜月, 寺嶋悠也, 松本和也, 廣瀬啓, 志田原健太, 縄稚翔一, 中土井崇人, 片山祐, 宮脇義亜, 勝山恵理, 勝山隆行, 楢崎真理子, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 68回 913 - 913 2024.3

婦人科悪性腫瘍の摘出後,速やかにCKが正常化したHMGCR抗体陽性壊死性ミオパチーの一例

古山怜奈, 勝山恵理, 久保田菜月, 寺嶋悠也, 松本和也, 廣瀬啓, 志田原健太, 縄稚翔一, 中土井崇人, 片山祐, 宮脇義亜, 勝山隆行, 楢崎真理子, 松本佳則, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 68回 915 - 915 2024.3

Pseudo pseudo Meigs syndromeを呈したSLEの1例

中山菜々子, 片山祐, 久保田菜月, 寺嶋悠也, 松本和也, 廣瀬啓, 志田原健太, 縄稚翔一, 中土井崇人, 宮脇義亜, 勝山恵理, 勝山隆行, 楢崎真理子, 松本佳則, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 68回 914 - 914 2024.3

上腸間膜動脈周囲軟部影から血管炎が疑われたが膵癌と判明した一例

志田原健太, 片山祐, 久保田菜月, 寺嶋悠也, 松本和也, 廣瀬啓, 中土井崇人, 縄稚翔一, 宮脇義亜, 勝山恵理, 勝山隆行, 楢崎真理子, 松本佳則, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 68回 881 - 881 2024.3

二次性の結節性多発動脈炎の発症したびまん性大細胞型B細胞性リンパ腫の一例

久保田菜月, 宮脇義亜, 寺嶋悠也, 松本和也, 廣瀬啓, 志田原健太, 中土井崇人, 縄稚翔一, 片山祐, 勝山隆行, 勝山恵理, 楢崎真理子, 松本佳則, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 68回 821 - 821 2024.3

骨免疫制御蛋白に着目した関節リウマチ病態形成メカニズムの解明

三前英恵, 松本佳則, 松本和也, 浅野洋介, 久保田菜月, 寺嶋悠也, 廣瀬啓, 縄稚翔一, 志田原健太, 中土井崇人, 片山祐, 宮脇義亜, 勝山恵理, 勝山隆行, 楢崎真理子, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 68回 910 - 910 2024.3

中小型血管炎:治療3 リツキシマブ1000mgの2回投与により寛解導入を行なった初発の顕微鏡的多発血管炎および多発血管炎性肉芽腫症の8例に関する記述研究

松本和也, 宮脇義亜, 久保田菜月, 寺嶋悠也, 廣瀬啓, 志田原健太, 中土井崇人, 縄稚翔一, 片山祐, 勝山隆行, 勝山恵理, 楢崎真理子, 松本佳則, 佐田憲映, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 68回 581 - 581 2024.3

不全型ベーチェット病に急性尿細管間質性腎炎を合併した一例

有地萌音, 勝山恵理, 久保田菜月, 寺嶋悠也, 松本和也, 廣瀬啓, 志田原健太, 縄稚翔一, 中土井崇人, 片山祐, 宮脇義亜, 勝山隆行, 楢崎真理子, 松本佳則, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 68回 909 - 909 2024.3

好酸球性多発血管炎性肉芽腫症(EGPA)との鑑別に苦慮した好酸球性大腸炎(EoC)の一例

寺嶋悠也, 宮脇義亜, 久保田菜月, 松本和也, 廣瀬啓, 志田原健太, 中土井崇人, 縄稚翔一, 片山祐, 勝山恵理, 勝山隆行, 楢崎真理子, 松本佳則, 和田淳

日本リウマチ学会総会・学術集会プログラム・抄録集 68回 889 - 889 2024.3

The first presentation of a case of nail-patella syndrome newly diagnosed at the onset of rheumatoid arthritis: a case report. International journal

Kazuya Matsumoto, Yoshinori Matsumoto, Shoichi Nawachi, Yosuke Asano, Yu Katayama, Yoshia Miyawaki, Takayuki Katsuyama, Eri Katsuyama, Yoshihisa Nasu, Ken-Ei Sada, Jun Wada

BMC musculoskeletal disorders 25 ( 1 ) 139 - 139 2024.2

Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: Nail-patella syndrome (NPS) is a rare autosomal dominant disorder that is characterized by dysplasia of the nails, hypoplasia and/or dislocation of the patella and the presence of iliac horns. Using the CARE guidelines, we present the first reported case of NPS that was newly diagnosed at the onset of rheumatoid arthritis (RA). CASE PRESENTATION: A 74-year-old man was admitted to our hospital due to an 8-month history of arthralgia in bilateral wrists, elbows and fingers. He had a past history of glaucoma and left patella dislocation that had been operatively recentered at the age of 15 years. Laboratory data showed elevated levels of serum C-reactive protein and rheumatoid factor and an elevated titer of anti-SS-A antibodies, while estimated glomerular filtration rate (eGFR), titers of other antibodies and the results of a urinary test were normal. An X-ray showed deformity of bilateral radial heads and the right elbow, and magnetic resonance imaging (MRI) of his hands showed synovitis and erosion in the multiple swollen joints of the wrists and fingers. In addition to these typical features of RA, he had bilateral thumb nail dysplasia with mild hypoplasia of bilateral patellae and iliac horns as shown by the X-ray. He was diagnosed as having autosomal dominant disorder NPS co-existing with RA and he was treated with methotrexate in combination with an oral Janus kinase (JAK) inhibitor, leading to induction of remission. CONCLUSIONS: We have presented a rare case of NPS that was newly diagnosed at the onset of RA. Clinical and radiographic findings of NPS are highlighted in this case report for diagnosing NPS on the basis of typical manifestations.

DOI： 10.1186/s12891-024-07242-2

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Infliximab biosimilar-induced lupus nephritis: A case report. International journal

Kenta Shidahara, Takayuki Katsuyama, Kei Hirose, Kazuya Matsumoto, Shoichi Nawachi, Takato Nakadoi, Yosuke Asano, Yu Katayama, Yoshia Miyawaki, Eri Katsuyama, Mariko Takano-Narazaki, Yoshinori Matsumoto, Ken-Ei Sada, Jun Wada

Modern rheumatology case reports 2023.10

Language：English Publishing type：Research paper (scientific journal)

We present a case of microhematuria, proteinuria and hypocomplementemia that developed in a 55-year-old female who was being treated with an infliximab biosimilar (IFX-BS) for rheumatoid arthritis (RA). Renal biopsy showed lupus nephritis (ISN/RPS classification class IV+V). Treatment with the IFX-BS was discontinued, and treatment with prednisolone, hydroxychloroquine and abatacept was started, resulting in clinical remission of lupus nephritis and RA. Although tumor necrosis factor-α (TNF-α) inhibitors are known to induce production of autoantibodies, symptoms are usually limited to skin involvement or arthritis, and renal complications are rare. Physicians should be aware of the risk of lupus nephritis and carefully monitor patients for the development of renal involvement during treatment with TNF-α inhibitors.

DOI： 10.1093/mrcr/rxad061

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Immunosuppressive Treatment for an anti-U1 Ribonucleoprotein Antibody-positive Patient with Pulmonary Arterial Hypertension: A Case Report.

Kazuya Matsumoto, Yoshia Miyawaki, Takayuki Katsuyama, Takato Nakadoi, Kenta Shidahara, Kei Hirose, Shoichi Nawachi, Yosuke Asano, Yu Katayama, Eri Katsuyama, Mariko Takano-Narazaki, Yoshinori Matsumoto, Atsushi Mori, Satoshi Akagi, Ken-Ei Sada, Jun Wada

Internal medicine (Tokyo, Japan) 2023.7

Language：English Publishing type：Research paper (scientific journal)

A 34-year-old woman with pulmonary arterial hypertension (PAH) was admitted to the hospital. She had been diagnosed with PAH three years earlier and treated with triple vasodilator therapy. She was positive for anti-U1 ribonucleoprotein antibodies but did not show any other symptoms associated with autoimmune diseases. Corticosteroid and cyclophosphamide therapy was administered, suspecting the involvement of immunological pathophysiology. After 3 weeks, the mean pulmonary artery pressure decreased from 50 to 38 mmHg without any change in the vasodilators. Immunosuppressive therapy was effective in this patient with PAH with an anti-U1 ribonucleoprotein-antibody-positive response and might be an option for patients with these specific features.

DOI： 10.2169/internalmedicine.1407-22

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