Updated on 2025/04/02

写真a

 
SHIMIZU Kazuyoshi
 
Organization
Scheduled update Lecturer
Position
Lecturer
External link

Degree

  • 博士(医学) ( 岡山大学 )

Research Interests

  • 小児心臓麻酔

  • Pediatric cardiac anesthesia

Research Areas

  • Life Science / Anesthesiology

Research History

  • 岡山大学病院   講師

    2024.5

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  • 岡山大学病院   助教

    2014.4 - 2024.4

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    Country:Japan

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  • - 岡山大学病院(手術部) 助教

    2014

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  • - Assistant Professor

    2014

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  • Assistant Professor

    2012 - 2014

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Professional Memberships

  • 日本心肺補助学会

    2024.1

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  • 日本呼吸療法医学会

    2017

  • 日本心臓血管麻酔学会

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  • 日本麻酔科学会

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  • 日本区域麻酔学会

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Committee Memberships

  • 日本集中治療医学会   日本集中治療医学会 小児集中治療委員  

    2021.4   

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    Committee type:Academic society

  • 日本心臓血管麻酔学会   日本心臓血管麻酔学会 集中治療 学術委員   

    2020.10   

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    Committee type:Academic society

  • 日本集中治療医学会   日本集中治療医学会評議員  

    2016.2   

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    Committee type:Academic society

  • 日本心臓血管麻酔学会   日本心臓血管麻酔学会専門医試験問題作成委員  

    2015.10 - 2019.3   

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    Committee type:Academic society

  • 日本麻酔科学会    日本麻酔科学会学術集会実行委員会 サテライトメンバー   

    2015.4   

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Papers

  • Association between plasma-free haemoglobin and postoperative acute kidney injury in paediatric cardiac surgery: a prospective observational study

    Takanobu Sakura, Tomoyuki Kanazawa, Tatsuhiko Shimizu, Kazuyoshi Shimizu, Tatsuo Iwasaki, Hiroshi Morimatsu

    BJA Open   12   100348 - 100348   2024.12

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    Publishing type:Research paper (scientific journal)   Publisher:Elsevier BV  

    DOI: 10.1016/j.bjao.2024.100348

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  • Oxygen Delivery During Cardiopulmonary Bypass in Pediatric Patients With Congenital Heart Disease: Association With Postoperative Acute Kidney Injury. International journal

    Hiroshi Taka, Takuma Douguchi, Ayako Miyamoto, Kazuyoshi Shimizu, Tatsuo Iwasaki, Tomoyuki Kanazawa, Satoshi Kimura, Hiroshi Morimatsu

    Journal of cardiothoracic and vascular anesthesia   2024.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    OBJECTIVE: This study was designed to investigate the distribution of nadir oxygen delivery (DO2), mean DO2, and area under ideal DO2 (AUiDO2) among categorized age groups of pediatric patients and their associations with postoperative cardiac surgery-associated (CSA) acute kidney injury (AKI) and clinical outcomes. DESIGN: Retrospective cohort study. SETTING: A tertiary teaching hospital. PARTICIPANTS: Patients aged <15 years with congenital heart disease who underwent cardiac surgery between May 2018 and May 2022. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Nadir DO2, mean DO2, and AUiDO2 were defined as the lowest DO2, average DO2, and dose of decrement combining the intensity and duration of DO2 less than the calculated ideal DO2, respectively. The primary outcome was CSA-AKI occurrence within 48 hours postoperatively. Secondary outcomes included maximum serum lactate levels (Lacmax) for the first 24 hours after pediatric cardiac intensive care unit admission. Of 479 patients, 147 (30.7%) developed AKI. Nadir DO2 and AUiDO2 were not significantly different between patients with CSA-AKI and those without CSA-AKI (p = 0.115 and p = 0.12, respectively). However, the mean DO2 was significantly higher in patients with CSA-AKI (p = 0.025). After adjusting for potential confounders, no significant differences were observed in the odds for CSA-AKI based on increments in nadir DO2, mean DO2, or AUiDO2. In contrast, nadir DO2 and mean DO2 were significantly associated with Lacmax in both univariate and multivariable regression analyses. CONCLUSION: DO2-related values during cardiopulmonary bypass were not associated with CSA-AKI in pediatric patients with congenital heart disease. However, nadir DO2 and mean DO2 were significantly associated with postoperative serum lactate levels.

    DOI: 10.1053/j.jvca.2024.11.017

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  • Perioperative gum-chewing training prevents a decrease in tongue pressure after esophagectomy in thoracic esophageal cancer patients: a nonrandomized trial. International journal

    Reiko Yamanaka-Kohno, Yasuhiro Shirakawa, Aya Yokoi, Naoaki Maeda, Shunsuke Tanabe, Kazuhiro Noma, Kazuyoshi Shimizu, Toshiharu Mituhashi, Yoshihide Nakamura, Souto Nanba, Yurika Uchida, Takayuki Maruyama, Manabu Morita, Daisuke Ekuni

    Scientific reports   14 ( 1 )   23886 - 23886   2024.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    Tongue pressure (TP) decreases significantly after esophagectomy in esophageal cancer patients (ECPs). Meanwhile, 2 weeks of gum-chewing training (GCT) significantly increased TP in healthy university students. We examined whether perioperative GCT would decrease the proportion of patients exhibiting a decline in TP at 2 weeks postoperatively, and prevent postoperative complications, in thoracic ECPs (TECPs). This was a single-center interventional study, and nonrandomized study with a historical control group (HCG). TECPs who underwent first-stage radical esophagectomy were recruited. Thirty-two patients of 40 in the gum-chewing group (GCG) were completed perioperative GCT in 3 times daily. Propensity score matching was performed with covariates related to TP including preoperative age, sex, body mass index, and the repetitive saliva swallowing test result, and yielded a matched cohort of 25 case pairs. Eleven GCG patients [44.0%] exhibited significantly lower TP at 2 weeks postoperatively than before esophagectomy was significantly fewer than that of 19 patients [76.0%] in the HCG. The median number of fever days (> 38 °C) in the 2 weeks after esophagectomy in the GCG was significantly fewer than those in the HCG. Perioperative GCT may prevent postoperative TP decline and postoperative dysphagia-related complications after esophagectomy.

    DOI: 10.1038/s41598-024-74090-4

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  • A Retrospective Comparative Study of the Frequency of Hypotension in Pediatric Cardiac Catheterization under General Anesthesia: Remimazolam versus Sevoflurane. International journal

    Tatsuhiko Shimizu, Tomoyuki Kanazawa, Tsubasa Yoshida, Takanobu Sakura, Kazuyoshi Shimizu, Tatsuo Iwasaki, Hiroshi Morimatsu

    Journal of cardiothoracic and vascular anesthesia   2024.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    OBJECTIVE: To compare the incidence of hypotension between remimazolam and sevoflurane under general anesthesia for cardiac catheterization in patients with congenital heart disease. DESIGN: Retrospective observational study. SETTING: A single university hospital with 300 pediatric cardiac catheterizations by general anesthesia performed annually. PARTICIPANTS: Patients younger than 15 years who underwent cardiac catheterization under general anesthesia between March 1, 2021, and December 31, 2022. Exclusion criteria were general anesthesia maintained with other than remimazolam or sevoflurane, receipt of remifentanil, American Society of Anesthesiologists score 4 or 5, emergency procedures, and no direct arterial pressure measurement. INTERVENTIONS: General anesthesia was maintained with remimazolam or sevoflurane. MEASUREMENTS AND MAIN RESULTS: A total of 309 patients were analyzed, including 28 in the remimazolam group and 281 in the sevoflurane group. Propensity score matching adjusted for confounding factors resulted in 28 patients in each arm, with no apparent differences in background factors. Hypotension was defined as a time-averaged area > 1, in which systolic arterial pressure fell below 80% of the baseline from the start of anesthesia to the end of procedure. The significance level was set at P < .05. The incidence of hypotension was 39.3% in the remimazolam arm and 46.4% in the sevoflurane arm, with no significant difference (P = .79), although the ratio of the median systolic arterial pressure to the baseline value was significantly higher in the remimazolam arm (91.4 ± 15.2% vs 83.2 ± 11.4% in the sevoflurane arm; P = .03). CONCLUSIONS: Remimazolam was not associated with a lower incidence of hypotension compared to sevoflurane during pediatric cardiac catheterization for congenital heart disease while maintaining significantly higher blood pressure overall.

    DOI: 10.1053/j.jvca.2024.08.038

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  • イソフルラン,プロポフォールを投与し鎮静薬を計画的に減量しえた長期人工呼吸管理の小児重症心不全例

    成谷 俊輝, 黒田 浩佐, 岡原 修司, 鈴木 聡, 金澤 伴幸, 清水 一好, 岩崎 達雄, 森松 博史

    日本集中治療医学会雑誌   31 ( 4 )   261 - 265   2024.7

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    Language:Japanese   Publisher:(一社)日本集中治療医学会  

    小児の長期にわたる鎮静は,薬剤耐性や医原性離脱症候群(iatrogenic withdrawal syndrome,IWS)を引き起こし,管理に難渋する場合がある。患者は14歳,男児。劇症型心筋炎と診断され左心補助人工心臓を必要とし,鎮痛鎮静薬は高用量かつ長期間投与となった。抜管に向けてIWS発症回避のため薬剤漸減の必要があったが,その過程での安全な管理のために抜管までは鎮静度の維持が必要と考えた。ミダゾラムとフェンタニルは12時間ごとに5%ずつ減量し,その間は適応外使用としてケタミン,イソフルラン,プロポフォールを順に投与し,鎮静度を維持した。プロポフォール中止後は速やかに覚醒が得られたため抜管し,ミダゾラム,フェンタニル中止後にデクスメデトミジンを漸減終了した。経過中はプロポフォール注入症候群,IWS,悪性高熱症を疑う所見を認めなかった。(著者抄録)

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    Other Link: https://search.jamas.or.jp/default/link?pub_year=2024&ichushi_jid=J02874&link_issn=&doc_id=20240719470006&doc_link_id=20240719470001&url=http%3A%2F%2Fsearch.jamas.or.jp%2Flink%2Fbc%2F20240719470001&type=jamaslink&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F99999_1.gif

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Books

  • 押さえておきたい小児心臓麻酔のツボ

    木村聡, 清水一好, 金澤伴幸( Role: Supervisor (editorial) ,  監修)

    メディカル・サイエンス・インターナショナル  2023.9  ( ISBN:9784815730802

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  • 【急性血液浄化法2020-'21-ガイドライン、スタンダード、論点そして私見-】急性血液浄化療法の適応疾患・臨床場面 頭蓋内病変合併例に対する血液浄化療法

    大岩 雅彦, 清水 一好, 森松 博史( Role: Contributor)

    救急・集中治療  2020.6 

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  • 【小児麻酔最新の知識】小児麻酔におけるデクスメデトミジン

    清水 一好, 金澤 伴幸, 岩崎 達雄( Role: Contributor)

    小児外科  2019.2 

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  • 救急・集中治療アドバンス 重症患者における急性肝不全・急性腎障害・代謝異常 4-2 AKIに対する血液浄化療法の開始と中止.

    中山書店  2018  ( ISBN:9784521743349

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  • 改訂版 小児心臓麻酔マニュアル

    メディカルフロントインターナショナル  2017  ( ISBN:9784902090833

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MISC

  • 先天性心疾患における壊死性腸炎

    清水達彦, 吉田翼, 佐倉考信, 金澤伴幸, 清水一好, 岩崎達雄

    日本小児循環器学会総会・学術集会(Web)   60th   2024

  • 小児麻酔 up to date小児心臓手術の麻酔 Invited Reviewed

    清水一好, 金澤伴幸, 岩崎達雄

    麻酔   72 ( 11 )   1024 - 1029   2023.11

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

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  • 食道閉鎖根治術後の食道右上葉肺瘻に対して2本のFogarty catheterで分離肺換気を行った一例

    吉田 翼, 金澤 伴幸, 佐倉 考信, 清水 達彦, 清水 一好, 岩崎 達雄

    日本小児麻酔学会誌   29 ( Suppl. )   178 - 178   2023.10

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    Language:Japanese   Publisher:(一社)日本小児麻酔学会  

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  • 全身麻酔下小児心臓カテーテルにおける低血圧発生率:レミマゾラムとセボフルランの後方視的比較検討

    清水 達彦, 金澤 伴幸, 吉田 翼, 佐倉 考信, 清水 一好, 岩崎 達雄, 森松 博史

    日本小児麻酔学会誌   29 ( Suppl. )   113 - 113   2023.10

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  • 術中から術後へのスムーズな集中治療管理への移行 術後心不全に対する対応

    清水 一好

    Cardiovascular Anesthesia   27 ( Suppl. )   125 - 125   2023.9

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    Language:Japanese   Publisher:(一社)日本心臓血管麻酔学会  

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Presentations

  • 「呼吸管理の実際と看護」 Invited

    清水一好

    岡山県看護研修セミナー  2022.11.24 

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    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • シンポジウム「臨床小児麻酔と小児集中治療をつなぐ〜ホットトピックスと多角的アプローチ」「小児心臓麻酔の最新知見」 Invited

    清水一好、金澤伴幸、岩崎達雄

    日本臨床麻酔学会 第42回大会  2022.11.11 

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    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

  • 小児の全身麻酔下におけるPatient State indexと呼気終末セボフルラン濃度の関連性:単施設後ろ向き研究

    清水 達彦、金澤 伴幸、吉田 翼、佐倉 考信、木村 聡、清水 一好、岩崎 達雄、森松 博史

    日本小児麻酔学会 第27回大会  2022.10.9 

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    Language:Japanese   Presentation type:Poster presentation  

  • Pros and Cons1Opioid free anesthesiaは必要か? Opioid-Free Anesthesiaのウィークポイント OFAは必要ない! Invited

    清水 達彦, 金澤 伴幸, 吉田 翼, 佐倉 考信, 木村 聡, 清水 一好, 岩崎 達雄, 森松 博史

    日本小児麻酔学会 第27回大会  2022.10.9 

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  • 小児心臓手術の人工心肺中の急激な CO2 貯留を脳波モニターで早期に検出できた1症例

    米澤みほこ、金澤 伴幸、吉田 翼、佐倉 孝信、清水 達彦、木村 聡、清水 一好、岩崎 達雄、森松 博史

    日本小児麻酔学会 第27回大会  2022.10.9 

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Research Projects

  • Multi-centered study for long-term outcomes after surgery-Influence of anesthetic management and postoperative analgesia-

    Grant number:21659366  2009 - 2011

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research  Grant-in-Aid for Challenging Exploratory Research

    NAKATSUKA Hideki, YOKOYAMA Masataka, MORIMATSU Hiroshi, SHIMIZU Kazuyoshi

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    Grant amount:\3280000 ( Direct expense: \3100000 、 Indirect expense:\180000 )

    A retrospective survey was conducted in patients undergoing major surgery under general anesthesia in 2008 to determine the profile of SAEs in Okayama University Hospital. We found that the incidence of SAEs was as high as 12.6%, similar to the percentage reported in other countries. ASA PS, emergency surgery, duration of surgery, and intraoperative colloid infusion and transfusion were good predictors of SAEs. We also conducted same survey in Kawasaki Medical School Hospital. We found that the incidence of SAEs was much lower than the incidence in Okayama University Hospital. We have to consider in detail about the background of the study patients in both institutions in order to find the reason of these differences.

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Class subject in charge

  • Anesthesiology and Resuscitology (2024academic year) special  - その他

  • Anesthesiology and Resuscitology (Core Clinical Practice) (2023academic year) special  - その他

  • Anesthesiology and Resuscitology (2023academic year) special  - その他

  • Anesthesiology and Resuscitology (Core Clinical Practice) (2022academic year) special  - その他

  • Anesthesiology and Resuscitology (2022academic year) special  - その他

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