研究者詳細 - 楊　家家

論文 - 楊　家家

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Contributions of the Primary Sensorimotor Cortex and Posterior Parietal Cortex to Motor Learning and Transfer 査読

Chenyu Wang, Yinghua Yu, Jiajia Yang

Brain Sciences 14 ( 12 ) 1184 - 1184 2024年11月

担当区分：最終著者,　責任著者記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：MDPI AG

Background: Transferring learned manipulations to new manipulation tasks has enabled humans to realize thousands of dexterous object manipulations in daily life. Two-digit grasp and three-digit grasp manipulations require different fingertip forces, and our brain can switch grasp types to ensure good performance according to motor memory. We hypothesized that several brain areas contribute to the execution of the new type of motor according to the motor memory. However, the motor memory mechanisms during this transfer period are still unclear. In the present functional magnetic resonance imaging (fMRI) study, we aimed to investigate the cortical mechanisms involved in motor memory during the transfer phase of learned manipulation tasks. Methods: Using a custom-built T-shaped object with an adjustable weight distribution, the participants performed grasp and lift manipulation tasks under different conditions to simulate the learning and transfer phases. The learning phase consisted of four grasp-and-lift repetitions with one motor type, followed by a transfer phase with four repetitions involving different motors (adding or removing a digit). Results: By comparing brain activity in the learning and transfer phases, we identified three regions (the superior frontal gyrus, supramarginal gyrus, and postcentral gyrus) associated with motor memory during the transfer of learned manipulations. Conclusions: Our findings improve the understanding of the role of the posterior parietal cortex in motor memory, highlighting how sensory information from memory and real-time input is integrated to generate novel motor control signals that guide the precise reapplication of control strategies. Furthermore, we believe that these areas contribute to motor learning from motor memory and may serve as key regions of interest for investigating neurodegenerative diseases.

DOI： 10.3390/brainsci14121184

The Power of Trial History: How Previous Trial Shapes Audiovisual Integration 査読

Xiaoyu Tang, Wanlong Liu, Yingnan Wu, Rongxia Ren, Jiaying Sun, Jiajia Yang, Aijun Wang, Ming Zhang

Multisensory Research 37 ( 6-8 ) 431 - 456 2024年11月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Brill

Abstract

Combining information from visual and auditory modalities to form a unified and coherent perception is known as audiovisual integration. Audiovisual integration is affected by many factors. However, it remains unclear whether the trial history can influence audiovisual integration. We used a target–target paradigm to investigate how the target modality and spatial location of the previous trial affect audiovisual integration under conditions of divided-modalities attention (Experiment 1) and modality-specific selective attention (Experiment 2). In Experiment 1, we found that audiovisual integration was enhanced in the repeat locations compared with switch locations. Audiovisual integration was the largest following the auditory targets compared to following the visual and audiovisual targets. In Experiment 2, where participants were asked to focus only on visual, we found that the audiovisual integration effect was larger in the repeat location trials than switch location trials only when the audiovisual target was presented in the previous trial. The present results provide the first evidence that trial history can have an effect on audiovisual integration. The mechanisms of trial history modulating audiovisual integration are discussed. Future examining of audiovisual integration should carefully manipulate experimental conditions based on the effects of trial history.

DOI： 10.1163/22134808-bja10133

その他リンク： https://brill.com/downloadpdf/journals/msr/37/6-8/article-p431_4.xml

Audiovisual integration and sensory dominance effects in older adults with subjective cognitive decline: Enhanced redundant effects and stronger fusion illusion susceptibility 査読

Shengnan Li, Weiping Yang, Yueying Li, Ruizhi Li, Zhilin Zhang, Satoshi Takahashi, Yoshimichi Ejima, Jinglong Wu, Mengni Zhou, Jiajia Yang

Brain and Behavior 14 ( 8 ) 2024年8月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Wiley

Abstract

Introduction

Subjective cognitive decline (SCD) refers to individuals’ perceived decline in memory and/or other cognitive abilities relative to their previous level of performance. Sensory decline is one of the main manifestations of decline in older adults with SCD. The efficient integration of visual and auditory information, known as audiovisual integration, is a crucial perceptual process. This study aims to evaluate audiovisual integration in older adults with SCD.

Methods

We adopted the audiovisual detection task, the Colavita task, and the Sound‐Induced Flash Illusion (SIFI) task to evaluate the audiovisual integration by examining both redundant and illusory effects. Older adults diagnosed with SCD (N = 50, mean age = 67.8 years) and a control group of non‐SCD older adults (N = 51, mean age = 66.5 years) were recruited. All participants took part in the three aforementioned experiments.

Results

The outcomes showed that a redundant effect occurred in both SCD and non‐SCD older adults, with SCD older adults gaining more benefits in audiovisual detection task. Moreover, an equivalent amount of the visual dominance effect was observed among both SCD and non‐SCD older adults in Colavita task. In addition, older adults with SCD perceived an equal fission illusion but a bigger fusion illusion compared with non‐SCD older adults in SIFI task.

Conclusions

Overall, older adults with SCD exhibit increased audiovisual redundant effects and stronger fusion illusion susceptibility compared to non‐SCD older adults. Besides, visual dominance was observed in both groups via the Colavita task, with no significant difference between non‐SCD and SCD older adults. These findings implied that audiovisual integration might offer a potential way for the identification of SCD.

DOI： 10.1002/brb3.3570

Psychological resilience is positively correlated with Habenula volume. 国際誌

Qi Dai, Yusuke Kyuragi, Halwa Zakia, Naoya Oishi, Lichang Yao, Zhilin Zhang, Luyao Wang, Jiajia Yang, Toshiya Murai, Hironobu Fujiwara

Journal of affective disorders 2024年8月

記述言語：英語掲載種別：研究論文（学術雑誌）

BACKGROUND: Psychological resilience is defined as the process and outcome of individuals' successful adaptation to challenging life experiences. The Habenula (Hb) is known to be involved in the stress response; however, the relationship between Hb volume and resilience in humans remains unclear. This study investigated the correlation among resilience, Hb volume, and depressive tendencies in adults. METHODS: Hb volumes were assessed using deep learning techniques applied to 110 healthy participants. Resilience and depression were evaluated using the Connor-Davidson Resilience Scale and Beck Depression Inventory-II, respectively. We examined the relationship between Hb volume and resilience and assessed the mediating effects of resilience on the relationship between Hb volume and depressive tendencies. RESULTS: Correlation analysis revealed a positive correlation between resilience and Hb volume (partial r = 0.176, p = 0.001), which was more pronounced in women (partial r = 0.353, p = 0.003). Hb volumes on the left and right sides exhibited significant lateralization (LI = 0.031, 95 % CI = [0.016, 0.046]). Despite Hb asymmetry, lateralization was not significantly associated with resilience. The mediation analysis shows significant indirect effect of resilience on the relationship between Hb volume and depressive tendencies (β = -0.093, 95%CI = [-0.189, -0.019]). CONCLUSION: This study found that populations with lower resilience have smaller Hb volume. Previous research has shown that Hb volume decreased with the increasing severity of depression symptoms in patients. Our findings support this view and extend it to a population that has not been clinically diagnosed with depression. Additionally, we found that psychological resilience can be predicted by Hb volume and may serve as a mediating factor indirectly affecting depressive tendencies, even in healthy individuals. LIMITATIONS: Due to its cross-sectional design, this study was unable to analyze dynamic changes in Hb volume during the process of resilience adaptation.

DOI： 10.1016/j.jad.2024.08.012

Perceptual training improves audiovisual integration by enhancing alpha-band oscillations and functional connectivity in older adults 査読

Yanna Ren, Peng Chen, Yan Li, Zhenhua Zhou, Yanping Dong, Shujing Li, Runqi Qian, Jiajia Yang, Jinglong Wu, Weiping Yang

Cerebral Cortex 34 ( 8 ) 2024年8月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Oxford University Press (OUP)

Abstract

Numerous studies on perceptual training exist, however, most have focused on the precision of temporal audiovisual perception, while fewer have concentrated on ability promotion for audiovisual integration (AVI). To investigate these issues, continuous 5-day audiovisual perceptual training was applied, during which electroencephalography was performed in response to auditory-only (A), visual-only (V) and audiovisual (AV) stimuli before and after training. The results showed that the perceptual sensitivity was greater for training group than for control group and was greater in the posttest than in the pretest. The response to the AV stimulus was significantly faster in the posttest than in the pretest for the older training group but was significantly greater for A and V stimuli for the younger training group. Electroencephalography analysis found higher P3 AVI amplitudes [AV-(A + V)] in the posttest than in the pretest for training group, which were subsequently reflected by an increased alpha (8–12 Hz) oscillatory response and strengthened global functional connectivity (weighted phase lag index). Furthermore, these facilitations were greater for older training groups than for younger training groups. These results confirm the age-related compensatory mechanism for AVI may be strengthened as audiovisual perceptual training progresses, providing an effective candidate for cognitive intervention in older adults.

DOI： 10.1093/cercor/bhae216

The human brain deals with violating general color or depth knowledge in different time courses 査読

Xiaoyu Tang, Shilong Yu, Shigeko Takahashi, Jiajia Yang, Yoshimichi Ejima, Yulin Gao, Qiong Wu, Jinglong Wu

Neuropsychologia 201 108941 - 108941 2024年8月

Tactile temporal predictions: The influence of conditional probability 査読

Rongxia Ren, Weichao An, Yinghua Yu, Xiaoyu Tang, Yoshimichi Ejima, Jinglong Wu, Jiajia Yang

i-Perception 15 ( 4 ) 2024年7月

担当区分：最終著者,　責任著者記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：SAGE Publications

Predicting the timing of incoming information allows brain to optimize information processing in dynamic environments. However, the effects of temporal predictions on tactile perception are not well established. In this study, two experiments were conducted to determine how temporal predictions interact with conditional probabilities in tactile perceptual processing. In Experiment 1, we explored the range of the interval between preceding ready cues and imperative targets in which temporal prediction effects can be observed. This prediction effect was observed for intervals of 500 and 1,000 ms. In Experiment 2, we investigated the benefits of temporal predictions on tactile perception while manipulating the conditional probability (setting the stimulus onset earlier or later than the predicted moment in short and long intervals). Our results revealed that this effect became stronger as the probability of the stimulus at the predicted time point increased under short-interval conditions. Together, our results show that the difficulty of transferring processing resources increases in temporally dynamic environments, suggesting a greater subjective cost associated with maladaptive responses to temporally uncertain events.

DOI： 10.1177/20416695241264736

その他リンク： https://journals.sagepub.com/doi/full-xml/10.1177/20416695241264736

Multi-hierarchy Network Configuration Can Predict Brain States and Performance 査読

Bin Wang, Yuting Yuan, Lan Yang, Yin Huang, Xi Zhang, Xingyu Zhang, Wenjie Yan, Ying Li, Dandan Li, Jie Xiang, Jiajia Yang, Miaomiao Liu

Journal of Cognitive Neuroscience 36 ( 8 ) 1695 - 1714 2024年7月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：MIT Press

Abstract

The brain is a hierarchical modular organization that varies across functional states. Network configuration can better reveal network organization patterns. However, the multi-hierarchy network configuration remains unknown. Here, we propose an eigenmodal decomposition approach to detect modules at multi-hierarchy, which can identify higher-layer potential submodules and is consistent with the brain hierarchical structure. We defined three metrics: node configuration matrix, combinability, and separability. Node configuration matrix represents network configuration changes between layers. Separability reflects network configuration from global to local, whereas combinability shows network configuration from local to global. First, we created a random network to verify the feasibility of the method. Results show that separability of real networks is larger than that of random networks, whereas combinability is smaller than random networks. Then, we analyzed a large data set incorporating fMRI data from resting and seven distinct tasking conditions. Experiment results demonstrates the high similarity in node configuration matrices for different task conditions, whereas the tasking states have less separability and greater combinability between modules compared with the resting state. Furthermore, the ability of brain network configuration can predict brain states and cognition performance. Crucially, derived from tasks are highlighted with greater power than resting, showing that task-induced attributes have a greater ability to reveal individual differences. Together, our study provides novel perspectives for analyzing the organization structure of complex brain networks at multi-hierarchy, gives new insights to further unravel the working mechanisms of the brain, and adds new evidence for tasking states to better characterize and predict behavioral traits.

DOI： 10.1162/jocn_a_02153

Go/No-Go Ratios Modulate Inhibition-Related Brain Activity: An Event-Related Potential Study 査読

Nan Zhang, Weichao An, Yinghua Yu, Jinglong Wu, Jiajia Yang

Brain Sciences 14 ( 5 ) 414 - 414 2024年4月

担当区分：最終著者,　責任著者記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：MDPI AG

(1) Background: Response inhibition refers to the conscious ability to suppress behavioral responses, which is crucial for effective cognitive control. Currently, research on response inhibition remains controversial, and the neurobiological mechanisms associated with response inhibition are still being explored. The Go/No-Go task is a widely used paradigm that can be used to effectively assess response inhibition capability. While many studies have utilized equal numbers of Go and No-Go trials, how different ratios affect response inhibition remains unknown; (2) Methods: This study investigated the impact of different ratios of Go and No-Go conditions on response inhibition using the Go/No-Go task combined with event-related potential (ERP) techniques; (3) Results: The results showed that as the proportion of Go trials decreased, behavioral performance in Go trials significantly improved in terms of response time, while error rates in No-Go trials gradually decreased. Additionally, the NoGo-P3 component at the central average electrodes (Cz, C1, C2, FCz, FC1, FC2, PCz, PC1, and PC2) exhibited reduced amplitude and latency; (4) Conclusions: These findings indicate that different ratios in Go/No-Go tasks influence response inhibition, with the brain adjusting processing capabilities and rates for response inhibition. This effect may be related to the brain’s predictive mechanism model.

DOI： 10.3390/brainsci14050414

Is P3 amplitude associated with greater gaze distraction effect in schizotypy? 査読国際誌

Zimo Li, Shuo Zhao, Jiajia Yang, Toshiya Murai, Shintaro Funahashi, Jinglong Wu, Zhilin Zhang

Schizophrenia research 267 422 - 431 2024年4月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Elsevier BV

A recently proposed "Hyperfocusing hypothesis" suggests that schizotypy is associated with a more narrow but more intense way of allocating attention. The current study aims to test a vital prediction of this hypothesis in a social context, that schizotypy may be related to greater difficulty overcoming the distracting effects of gaze. This could cause a longer time to respond to targets that are invalidly cued by gaze. The current study tested this prediction in a modified Posner cueing paradigm by using P3 as an indicator for attentional resources. Seventy-four young healthy individuals with different levels of schizotypy were included, they were asked to detect the location of a target that was cued validly or invalidly by the gaze and head orientation. The results revealed that (a) schizotypy is associated with hyperfocusing on gaze direction, leading to greater difficulty overcoming the distracting effect of gaze. The higher the trait-schizotypy score, the more time needed to respond to targets that were invalidly cued by gaze (b) schizotypy is associated with reduced P3 which is directed by social communicative stimuli. The higher the trait-schizotypy score, the smaller the amplitude of P3 (c) the relationship between schizotypal traits and response times of the gaze-invalid condition is fully intermediated by P3. The findings of the current study suggest the P3 component may be a crucial neural mechanism underlying joint attention deficits in schizophrenia.

DOI： 10.1016/j.schres.2024.04.006

Phonological properties of logographic words modulate brain activation in bilinguals: a comparative study of Chinese characters and Japanese Kanji 査読

Zhenglong Lin, Xiujun Li, Geqi Qi, Jiajia Yang, Hongzan Sun, Qiyong Guo, Jinglong Wu, Min Xu

Cerebral Cortex 34 ( 4 ) 2024年4月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Oxford University Press (OUP)

Abstract

The brain networks for the first (L1) and second (L2) languages are dynamically formed in the bilingual brain. This study delves into the neural mechanisms associated with logographic–logographic bilingualism, where both languages employ visually complex and conceptually rich logographic scripts. Using functional Magnetic Resonance Imaging, we examined the brain activity of Chinese–Japanese bilinguals and Japanese–Chinese bilinguals as they engaged in rhyming tasks with Chinese characters and Japanese Kanji. Results showed that Japanese–Chinese bilinguals processed both languages using common brain areas, demonstrating an assimilation pattern, whereas Chinese–Japanese bilinguals recruited additional neural regions in the left lateral prefrontal cortex for processing Japanese Kanji, reflecting their accommodation to the higher phonological complexity of L2. In addition, Japanese speakers relied more on the phonological processing route, while Chinese speakers favored visual form analysis for both languages, indicating differing neural strategy preferences between the 2 bilingual groups. Moreover, multivariate pattern analysis demonstrated that, despite the considerable neural overlap, each bilingual group formed distinguishable neural representations for each language. These findings highlight the brain’s capacity for neural adaptability and specificity when processing complex logographic languages, enriching our understanding of the neural underpinnings supporting bilingual language processing.

DOI： 10.1093/cercor/bhae150

Event-related potential evidence for tactile orientation processing in the human brain 査読

Jiajia Yang, Rongxia Ren, Yinghua Yu, Wu Wang, Xiaoyu Tang, Yoshimichi Ejima, Jinglong Wu

Experimental Brain Research 242 ( 4 ) 809 - 817 2024年2月

担当区分：筆頭著者,　責任著者記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Springer Science and Business Media LLC

Abstract

It is well known that information on stimulus orientation plays an important role in sensory processing. However, the neural mechanisms underlying somatosensory orientation perception are poorly understood. Adaptation has been widely used as a tool for examining sensitivity to specific features of sensory stimuli. Using the adaptation paradigm, we measured event-related potentials (ERPs) in response to tactile orientation stimuli presented pseudo-randomly to the right-hand palm in trials with all the same or different orientations. Twenty participants were asked to count the tactile orientation stimuli. The results showed that the adaptation-related N60 component was observed around contralateral central-parietal areas, possibly indicating orientation processing in the somatosensory regions. Conversely, the adaptation-related N120 component was identified bilaterally across hemispheres, suggesting the involvement of the frontoparietal circuitry in further tactile orientation processing. P300 component was found across the whole brain in all conditions and was associated with task demands, such as attention and stimulus counting. These findings help provide an understanding of the mechanisms of tactile orientation processing in the human brain.

DOI： 10.1007/s00221-024-06783-1

その他リンク： https://link.springer.com/article/10.1007/s00221-024-06783-1/fulltext.html

Audiovisual n-Back Training Alters the Neural Processes of Working Memory and Audiovisual Integration: Evidence of Changes in ERPs 査読

Ao Guo, Weiping Yang, Xiangfu Yang, Jinfei Lin, Zimo Li, Yanna Ren, Jiajia Yang, Jinglong Wu

Brain Sciences 13 ( 7 ) 992 - 992 2023年6月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：MDPI AG

(1) Background: This study investigates whether audiovisual n-back training leads to training effects on working memory and transfer effects on perceptual processing. (2) Methods: Before and after training, the participants were tested using the audiovisual n-back task (1-, 2-, or 3-back), to detect training effects, and the audiovisual discrimination task, to detect transfer effects. (3) Results: For the training effect, the behavioral results show that training leads to greater accuracy and faster response times. Stronger training gains in accuracy and response time using 3- and 2-back tasks, compared to 1-back, were observed in the training group. Event-related potentials (ERPs) data revealed an enhancement of P300 in the frontal and central regions across all working memory levels after training. Training also led to the enhancement of N200 in the central region in the 3-back condition. For the transfer effect, greater audiovisual integration in the frontal and central regions during the post-test rather than pre-test was observed at an early stage (80–120 ms) in the training group. (4) Conclusion: Our findings provide evidence that audiovisual n-back training enhances neural processes underlying a working memory and demonstrate a positive influence of higher cognitive functions on lower cognitive functions.

DOI： 10.3390/brainsci13070992

Auditory affective content facilitates time-to-contact estimation of visual affective targets 査読

Feifei Lu, You Li, Jiajia Yang, Aijun Wang, Ming Zhang

Frontiers in Psychology 14 2023年5月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Frontiers Media SA

Reacting to a moving object requires an ability to estimate when a moving object reaches its destination, also referred to as the time-to-contact (TTC) estimation. Although the TTC estimation of threatening visually moving objects is known to be underestimated, the effect of the affective content of auditory information on visual TTC estimation remains unclear. We manipulated the velocity and presentation time to investigate the TTC of a threat or non-threat target with the addition of auditory information. In the task, a visual or an audiovisual target moved from right to left and disappeared behind an occluder. Participants’ task was to estimate the TTC of the target, they needed to press a button when they thought that the target contacted a destination behind the occluder. Behaviorally, the additional auditory affective content facilitated TTC estimation; velocity was a more critical factor than presentation time in determining the audiovisual threat facilitation effect. Overall, the results indicate that exposure to auditory affective content can influence TTC estimation and that the effect of velocity on TTC estimation will provide more information than presentation time.

DOI： 10.3389/fpsyg.2023.1105824

Aging effect of cross-modal interactions during audiovisual detection and discrimination by behavior and ERPs 査読

Yanna Ren, Yan Li, Zhihan Xu, Rui Luo, Runqi Qian, Jieping Duan, Jiajia Yang, Weiping Yang

Frontiers in Aging Neuroscience 15 2023年4月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Frontiers Media SA

Introduction

Numerous studies have shown that aging greatly affects audiovisual integration; however, it is still unclear when the aging effect occurs, and its neural mechanism has yet to be fully elucidated.

Methods

We assessed the audiovisual integration (AVI) of older (n = 40) and younger (n = 45) adults using simple meaningless stimulus detection and discrimination tasks. The results showed that the response was significantly faster and more accurate for younger adults than for older adults in both the detection and discrimination tasks. The AVI was comparable for older and younger adults during stimulus detection (9.37% vs. 9.43%); however, the AVI was lower for older than for younger adults during stimulus discrimination (9.48% vs. 13.08%) behaviorally. The electroencephalography (EEG) analysis showed that comparable AVI amplitude was found at 220–240 ms for both groups during stimulus detection and discrimination, but there was no significant difference between brain regions for older adults but a higher AVI amplitude in the right posterior for younger adults. Additionally, a significant AVI was found for younger adults in 290–310 ms but was absent for older adults during stimulus discrimination. Furthermore, significant AVI was found in the left anterior and right anterior at 290–310 ms for older adults but in the central, right posterior and left posterior for younger adults.

Discussion

These results suggested that the aging effect of AVI occurred in multiple stages, but the attenuated AVI mainly occurred in the later discriminating stage attributed to attention deficit.

DOI： 10.3389/fnagi.2023.1151652

Spatial frequencies affect cuteness perception of infant faces. 査読

Mengni Zhou, Huazhi Li, Qingqing Li, Tsubasa Uehara, Lichang Yao, Jiajia Yang, Yoshimichi Ejima, Satoshi Takahashi, Jinglong Wu

Emotion 23 ( 2 ) 512 - 520 2023年3月

Audiovisual illusion training improves multisensory temporal integration 査読

Haocheng Zhu, Xiaoyu Tang, Tingji Chen, Jiajia Yang, Aijun Wang, Ming Zhang

Consciousness and Cognition 109 103478 - 103478 2023年3月

Sustained visual attentional load modulates audiovisual integration in older and younger adults 査読

Yanna Ren, Hannan Li, Yan Li, Zhihan Xu, Rui Luo, Hang Ping, Xuan Ni, Jiajia Yang, Weiping Yang

i-Perception 14 ( 1 ) 204166952311573 - 204166952311573 2023年1月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：SAGE Publications

Previous studies have shown that attention influences audiovisual integration (AVI) in multiple stages, but it remains unclear how AVI interacts with attentional load. In addition, while aging has been associated with sensory-functional decline, little is known about how older individuals integrate cross-modal information under attentional load. To investigate these issues twenty older adults and 20 younger adults were recruited to conduct a dual task including a multiple object tracking (MOT) task, which manipulated sustained visual attentional load, and an audiovisual discrimination task, which assesses AVI. The results showed that response times were shorter and hit rate was higher for audiovisual stimuli than for auditory or visual stimuli alone and in younger adults than in older adults. The race model analysis showed that AVI was higher under the load_3 condition (monitoring two targets of the MOT task) than under any other load condition (no-load [NL], one or three targets monitoring). This effect was found regardless of age. However, AVI was lower in older adults than younger adults under NL condition. Moreover, the peak latency was longer, and the time window of AVI was delayed in older adults compared to younger adults under all conditions. These results suggest that slight visual sustained attentional load increased AVI but that heavy visual sustained attentional load decreased AVI, which supports the claim that attention resource was limited, and we further proposed that AVI was positively modulated by attentional resource. Finally, there were substantial impacts of aging on AVI; AVI was delayed in older adults.

DOI： 10.1177/20416695231157348

その他リンク： http://journals.sagepub.com/doi/full-xml/10.1177/20416695231157348

Sound-induced flash illusions at different spatial locations were affected by personality traits 査読

Heng Zhou, Shuqi Li, Jie Huang, Jiajia Yang, Aijun Wang, Ming Zhang

Attention, Perception, & Psychophysics 85 ( 2 ) 463 - 473 2022年12月

Altered higher-order coupling between brain structure and function with embedded vector representations of connectomes in schizophrenia 査読

Bin Wang, Min Guo, Tingting Pan, Zhifeng Li, Ying Li, Jie Xiang, Xiaohong Cui, Yan Niu, Jiajia Yang, Jinglong Wu, Miaomiao Liu, Dandan Li

Cerebral Cortex 33 ( 9 ) 5447 - 5456 2022年12月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Oxford University Press (OUP)

Abstract

It has been shown that the functional dependency of the brain exists in both direct and indirect regional relationships. Therefore, it is necessary to map higher-order coupling in brain structure and function to understand brain dynamic. However, how to quantify connections between not directly regions remains unknown to schizophrenia. The word2vec is a common algorithm through create embeddings of words to solve these problems. We apply the node2vec embedding representation to characterize features on each node, their pairwise relationship can give rise to correspondence relationships between brain regions. Then we adopt pearson correlation to quantify the higher-order coupling between structure and function in normal controls and schizophrenia. In addition, we construct direct and indirect connections to quantify the coupling between their respective functional connections. The results showed that higher-order coupling is significantly higher in schizophrenia. Importantly, the anomalous cause of coupling mainly focus on indirect structural connections. The indirect structural connections play an essential role in functional connectivity–structural connectivity (SC–FC) coupling. The similarity between embedded representations capture more subtle network underlying information, our research provides new perspectives for understanding SC–FC coupling. A strong indication that the structural backbone of the brain has an intimate influence on the resting-state functional.

DOI： 10.1093/cercor/bhac432

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