Faculty Profiles - MATSUO Toshihiko

Papers - MATSUO Toshihiko

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Multiple sclerosis-like disease secondary to alpha interferon Reviewed

T Matsuo, R Takabatake

OCULAR IMMUNOLOGY AND INFLAMMATION 10 ( 4 ) 299 - 304 2002.12

Seropositivity of human herpesvirus-8 in patients with uveitis Reviewed

T Matsuo, M Itami

OCULAR IMMUNOLOGY AND INFLAMMATION 10 ( 3 ) 197 - 199 2002.9

Submacular exudates with serous retinal detachment caused by cat scratch disease Reviewed

T Matsuo, M Kato

OCULAR IMMUNOLOGY AND INFLAMMATION 10 ( 2 ) 147 - 150 2002.6

The incidence and pathology of conjunctival ulceration in Behcet's syndrome Reviewed

T Matsuo, M Itami, H Nakagawa, M Nagayama

BRITISH JOURNAL OF OPHTHALMOLOGY 86 ( 2 ) 140 - 143 2002.2

Two cases of ocular injury due to air-bag activation

F. Nonaka, M. Nagayama, T. Matsuo, F. Shiraga, H. Ohtsuki

Japanese Journal of Clinical Ophthalmology 55 ( 2 ) 158 - 162 2001

A novel gene (retinovin) expressed selectively in the early stage of chick retinal development Reviewed

M Itami, T Matsuo, H Ohtsuki

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 276 ( 1 ) 12 - 15 2000.9

Identification of ingrowth site of idiopathic subfoveal choroidal neovascularization by indocyanine green angiography Reviewed

Fumio Shiraga, Chieko Shiragami, Toshihiko Matsuo, Shiho Yokoe, Ippei Takasu, Hiroshi Ohtsuki

Ophthalmology 107 ( 3 ) 600 - 607 2000.3

Risk for ocular attacks following phacoemulsification and intraocular lens implantation in patients of Behcet disease

M. Takahashi, T. Matsuo, A. Yamaoka, H. Kuwada, H. Ohtsuki, Y. Inoue, K. Egi

Japanese Journal of Clinical Ophthalmology 54 ( 8 ) 1499 - 1502 2000

Surgical treatment of submacular hemorrhage associated with idiopathic polypoidal choroidal vasculopathy Reviewed

Fumio Shiraga, Toshihiko Matsuo, Shiho Yokoe, Ippei Takasu, Toshio Okanouchi, Hiroshi Ohtsuki, Hans E. Grossniklaus

American Journal of Ophthalmology 128 ( 2 ) 147 - 154 1999.8

A novel gene (oculomedin) induced by mechanical stretching in human trabecular cells of the eye Reviewed

Yukiko Sato, Toshihiko Matsuo, Hiroshi Ohtsuki

Biochemical and Biophysical Research Communications 259 ( 2 ) 349 - 351 1999.6

Choroidal abnormalities in Behçet disease observed by simultaneous indocyanine green and fluorescein angiography with scanning laser ophthalmoscopy. Reviewed International journal

T Matsuo, Y Sato, F Shiraga, C Shiragami, Y Tsuchida

Ophthalmology 106 ( 2 ) 295 - 300 1999.2

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: To examine choroidopathy in patients with Behçet disease. DESIGN: Prospective clinical study. PARTICIPANTS: Thirty-three patients (63 eyes) with Behçet disease. INTERVENTION: Patients underwent simultaneous indocyanine green (ICG) and fluorescein angiography with a double detector of scanning laser ophthalmoscopy. MAIN OUTCOME MEASURES: Angiographic findings recorded on videotapes were evaluated. The relation of angiographic findings with systemic activity and aqueous inflammation was also analyzed. RESULTS: Fluorescein angiography showed leakage in varying degrees from retinal vessels in 30 patients (53 eyes, 84%). The ICG angiographic findings were choroidal vascular wall staining in 16 eyes (25%), hyperfluorescent spots in 42 eyes (66%) and hypofluorescent plaques in 22 eyes (35%), both of which were not evident with fluorescein, leakage from choroidal vessels in 3 eyes (5%), and irregular filling of choriocapillaris in 11 eyes (17%). These findings did not have a statistically significant correlation with the presence or absence of aqueous inflammation or oral aphthous ulcerations. CONCLUSIONS: The patients with Behçet disease showed choroidal abnormalities, which could be revealed only by ICG angiography, but not with funduscopy or fluorescein angiography. Simultaneous ICG and fluorescein angiography would be useful for examining choroidal lesions in Behçet disease.

PubMed

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Choroidal lesions in sarcoidosis evaluated by indocyanine green angiography

M. Itami, T. Matsuo, C. Shiragami, F. Shiraga, Y. Sato, H. Ohtsuki

Japanese Journal of Clinical Ophthalmology 53 ( 4 ) 641 - 644 1999

Transplanted and repopulated retinal pigment epithelial cells on damaged Bruch's membrane in rabbits. International journal

C Shiragami, T Matsuo, F Shiraga, N Matsuo

The British journal of ophthalmology 82 ( 9 ) 1056 - 62 1998.9

Language：English Publishing type：Research paper (scientific journal)

AIMS: The authors studied how artificially damaged Bruch's membrane influenced growth and differentiation of transplanted embryonic retinal pigment epithelial (RPE) cells and of host RPE cells in rabbits. METHODS: Embryonic RPE cells obtained from pigmented rabbits were transplanted into the subretinal space of adult albino rabbits. The host RPE was removed with a silicone cannula, and Bruch's membrane was damaged by scratching with a microhooked 27 gauge needle under the detached retina in closed vitrectomy. The transplantation sites were examined 3, 7, and 14 days after surgery by light and electron microscopy. RESULTS: Varying degrees of damage in Bruch's membrane were observed. Pigmented and hypopigmented RPE cells showed a normal polarity and tight junctions were seen at the sites of mild to moderate damage 3-7 days after the surgery. In contrast, fibroblast-like cells with no such features of RPE cells formed multiple layers at the sites of severe damage involving the full thickness of Bruch's membrane and the choriocapillaris even 14 days after the surgery. Without transplantation, host RPE cells repopulated the damaged areas in the same way as transplanted RPE cells. CONCLUSIONS: Transplanted embryonic RPE cells as well as host RPE cells grew and differentiated on the moderately damaged Bruch's membrane, while the severely damaged Bruch's membrane did not allow differentiation of RPE cells although these cells could grow and cover the damaged areas.

PubMed

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Bovine trabecular cells produce TIMP-1 and MMP-2 in response to mechanical stretching Reviewed

Y Okada, T Matsuo, H Ohtsuki

JAPANESE JOURNAL OF OPHTHALMOLOGY 42 ( 2 ) 90 - 94 1998.3

Aqueous vascular endothelial growth factor increases in anterior segment ischemia in rabbits Reviewed

T Tanaka, T Matsuo, H Ohtsuki

JAPANESE JOURNAL OF OPHTHALMOLOGY 42 ( 2 ) 85 - 89 1998.3

Geographic choroiditis and retinal vasculitis in rheumatoid arthritis Reviewed

Toshihiko Matsuo, Ikuya Masuda, Nobuhiko Matsuo

Japanese Journal of Ophthalmology 42 ( 1 ) 51 - 55 1998.1

Metastasis to the iris in squamous cell lung cancer Reviewed

Akio Hiraki, Hiroshi Ueoka, Toshihiko Matsuo, Tomio Nakagawa, Tadashi Yoshino, Katsuyuki Kiura, Masahiro Tabata, Katsuyoshi Sakae, Yuji Ohtsuki, Yoshio Hiraki, Mine Harada

International Journal of Clinical Oncology 3 ( 3 ) 186 - 190 1998

A case of atypical Treacher-Collins syndrome

Hirotake Fujiwara, Michio Sugihara, Toshihiko Matsuo, Miki Nouso, Satoshi Hasebe, Hiroshi Ohtsuki

Folia Ophthalmologica Japonica 48 ( 9 ) 1154 - 1157 1997.9

Bilateral iridocyclitis with retinal capillaritis in juveniles Reviewed

T. Matsuo, N. Matsuo

Ophthalmology 104 ( 6 ) 939 - 944 1997

Abducens nerve palsy in a case under treatment with systemic interferon

M. Hosogi, S. Hasebe, T. Matsuo, H. Ohtsuki

Japanese Journal of Clinical Ophthalmology 51 ( 7 ) 1357 - 1360 1997

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