Updated on 2024/10/18

写真a

 
HIKASA Haruka
 
Organization
Faculty of Interdisciplinary Science and Engineering in Health Systems Associate Professor
Position
Associate Professor
External link

Degree

  • 博士(文学) ( 東北大学 )

Research Interests

  • 生命倫理学

  • 臨床死生学

  • 意思決定

  • 自律

  • 最善の利益

Research Areas

  • Humanities & Social Sciences / Philosophy and ethics  / 生命倫理学

Education

  • 東北大学大学院文学研究科文化科学専攻哲学専攻分野 博士課程後期3年の課程    

    2006.4 - 2012.2

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  • 東北大学大学院文学研究科文化科学専攻哲学専攻分野 博士課程前期2年の課程    

    2004.4 - 2006.3

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  • Okayama University   文学部   人間学科

    2000.4 - 2004.3

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Research History

  • Okayama University   大学院ヘルスシステム統合科学研究科   Lecturer

    2018.4

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  • 日本学術振興会特別研究員(RPD)   (うち、2014年10月から2015年3月まで研究中断・研究再開準備支援期間を取得。)

    2014.4 - 2017.7

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  • 日本学術振興会特別研究員   (うち、2012年7月から2013年12月まで研究中断および研究再開準備支援期間を取得。)

    2010.4 - 2014.3

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Papers

  • 無反応覚醒症候群をめぐる確率論的転回 ―誤診率を手がかりとしたケアの方法論を出発点として― Reviewed

    戸田聡一郎, 日笠晴香

    生命倫理   33 ( 1 )   86 - 94   2022.9

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  • Evaluation of skin sensitization based on interleukin‑2 promoter activation in Jurkat cells International journal

    Taichi Nagahata, Yoshio Tsujino, Eiji Takayama, Haruka Hikasa, Ayano Satoh

    Biomedical Reports   16 ( 1 )   3 - 3   2021.11

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Spandidos Publications  

    Skin sensitization is an allergic reaction caused by certain chemical substances, and is an important factor to be taken into consideration when evaluating the safety of numerous types of products. Although animal testing has long been used to evaluate skin sensitization, the recent trend to regulate such testing has led to the development and use of alternative methods. Skin sensitization reactions are summarized in the form of an adverse outcome pathway consisting of four key events (KE), including covalent binding to skin proteins (KE1), keratinocyte activation (KE2), and dendritic cell activation (KE3). Equivalent alternative methods have been developed for KE1 to KE3, but no valid alternative has yet been developed for the evaluation of KE4 and T-cell activation. Current alternative methods rely on data from KE1 to KE3 to predict the effect of chemicals on skin sensitization. The addition of KE4 data is expected to improve the accuracy and reproducibility of such predictions. The aim of this study was to establish an assay to evaluate KE4 T-cell activation to supplement data on skin sensitization related to KE4. To evaluate T-cell activation, the Jurkat T-cell line stably expressing luciferase downstream of the pro-inflammatory cytokine interleukin-2 promoter was used. After exposure to known skin sensitizing agents and control substances, luciferase activity measurements revealed that this assay was valid for evaluating skin sensitization. However, two skin sensitizers known to have immunosuppressive effects on T-cells reacted negatively in this assay. The results revealed that this assay simultaneously allows for monitoring of the skin sensitization and immuno-suppressiveness of chemical substances and supplements KE4 T-cell activation data, and may thus contribute to reducing the use of animal experiments.

    DOI： 10.3892/br.2021.1486

    PubMed

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  • 意思決定における自律尊重の考察――価値の一貫性と変化の観点から Reviewed

    日笠 晴香

    生命倫理   ( 26 )   96 - 103   2015

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    Publishing type：Research paper (scientific journal)  

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  • 意思決定における自律と最善の利益 Reviewed

    日笠 晴香

    東北大学   2013

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    Publishing type：Doctoral thesis  

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  • 認知症患者の意思決定と脳神経科学

    日笠 晴香

    MORALIA   ( 15 )   53 - 71   2008

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  • One human life or different persons: over the validity of advance directives Reviewed

    HIKASA Haruka

    Annals of the Japanese Association for Philosophical and Ethical Researches of Medicine   ( 25 )   41 - 50   2007

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    Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The japanese Association for Philosophical and Ethical Researches in Medicine  

    Advance directives are statements made beforehand by a person who was competent at the time about the care he/she wishes to receive if he/she were to become incompetent in the future. They are thus means of determining the patient's will when surrogate decision-making is needed. However, difficult problems may arise if advance directives conflict with the interests of the patient as judged by the people around him/her. This paper will explore this issue, focusing on advance directives of dementia patients. Theorists have varying opinions on the advance directives provided by dementia patients when they were competent. R. Dworkin argues that if someone has made a prior expression that "I will refuse any medical treatment at the terminal stage of dementia", we should not give the person any treatment at all. In contrast, R. Dresser asserts that "a dementia patient is a 'different person' from the person who made the advance directive", so that advance directives should be overridden if the current benefits of treatment the dementia patient may obtain are greater than the burden resulting from it. M. Quante asserts that advance directives should be respected as long as they do not cause actual pain or harm to dementia patients. The differences between these assertions are, in my view, based on differing views regarding the "personality" of incompetent dementia patients. Dementia patients have lost their personalities, according to Dworkin and Quante, while they have a "different personality" according to Dresser. However, a dementia patient and the person he/she used to be cannot be completely severed, for he/she is a being who lives one human life. Therefore, in order to make decisions on behalf of the patient, I suggest the need to distinguish him/her from the person who he/she used to be while at the same time regarding him/her as a person who lives one human life.

    CiNii Article

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    Other Link： http://search.jamas.or.jp/link/ui/2008082710

  • R･ドゥオーキンにおける生の不可侵性と生死に関する決定 Reviewed

    日笠 晴香

    思索   ( 39 )   83 - 102   2006

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    Language：Japanese   Publisher：東北大学哲学研究会  

    CiNii Article

    CiNii Books

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Books

  • コンパッション都市：公衆衛生と終末期ケアの融合

    竹之内裕文, 堀田聰子（ Role： Joint translator ,  第3章、第4章）

    慶應義塾大学出版会  2022.10  （ ISBN:4766428269 ）

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    Total pages：384   Language：Japanese Book type：Scholarly book

    CiNii Books

    ASIN

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  • 臨床倫理の考え方と実践: 医療・ケアチームのための事例検討法

    清水, 哲郎, 会田, 薫子, 田代, 志門（ Role： Joint author ,  Ⅲアドバンスト編 1「本人の意思を尊重するということ：「自律」・「自己決定」再考」（86-91頁）を担当。）

    東京大学出版会  2022.1  （ ISBN:4130624237 ）

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    Total pages：180   Language：Japanese Book type：Scholarly book

    CiNii Books

    ASIN

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  • 尊厳と社会

    加藤, 泰史, 小島, 毅（ Role： Joint author ,  第2章「認知症患者の尊厳と医療ケアの意思決定――自律尊重と利益保護をめぐって――」（161-186頁）を担当。）

    法政大学出版局  2020.3  （ ISBN:9784588151071 ）

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    Total pages：2冊   Language：Japanese Book type：Scholarly book

    CiNii Books

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  • 老い―人文学・ケアの現場・老年学 ―

    本村昌文他編（ Role： Joint editor ,  4章「意思決定と感情の能力」（93-112頁）を担当。）

    ポラーノ出版  2019.2 

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    刊行予定。

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  • 子宮内膜症で悩んでいるあなたへ 意思決定プロセスノート

    日笠晴香, 圓増文著, 清水哲郎, 会田薫子監修（ Role： Joint author）

    医学と看護社  2018 

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  • ケースで学ぶ 認知症ケアの倫理と法

    松田純, 堂囿俊彦, 青田安史, 天野ゆかり, 宮下修一編（ Role： Joint author ,  コラム「事前指示」（119-120頁）を担当。）

    南山堂  2017 

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  • どう生き どう死ぬか――現場から考える死生学

    清水哲郎監修, 岡部健, 竹之内裕文編（ Role： Joint author ,  第3章「最期の選択 だれが、なにを、どうやって決めるのか」およびコラム3「告知とインフォームド・コンセント」（49-69頁）を担当。）

    弓箭書院  2009 

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  • 高齢社会を生きる 老いる人／看取るシステム

    清水哲郎編（ Role： Joint author ,  第2章「予め決めておく――事前指示をどう考えるか」（47-68頁）を担当。）

    東信堂  2007 

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MISC

  • 統合科学次世代研究会の活動報告

    吉岡朋彦, 日笠晴香

    統合科学   2 ( 1 )   37 - 39   2022.3

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  • ACPの目標と本人の死生観

    日笠 晴香

    看護展望   44 ( 11 )   16 - 20   2019.9

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  • 『最期の選択』をどう考えるか

    日笠 晴香

    東北大学臨床死生学研究会研究報告   ( 1 )   7 - 16   2010

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Presentations

  • 十分な意思決定能力を持たないと判断される人の意思決定プロセスにおける「説明」

    日笠晴香

    第34回日本生命倫理学会年次大会  2022.11.19 

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    Event date： 2022.11.19 - 2022.11.20

    Presentation type：Symposium, workshop panel (public)  

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  • どのような意思決定が尊重されるべきか―自律の観点から―

    日笠晴香

    第41回医学哲学・倫理学会大会  2022.10.10 

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    Event date： 2022.10.8 - 2022.10.10

    Presentation type：Symposium, workshop panel (nominated)  

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  • 認知症の人のケアに携わる専門職者の意思決定に関するかかわり

    工藤 洋子, 日笠 晴香

    日本在宅看護学会学術集会  2021.11 

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    Event date： 2021.11.13 - 2021.11.14

    Presentation type：Oral presentation (general)  

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  • Investigation of clinical ethics on decision-making in the end of life care

    Haruka Hikasa

    The 11th International Symposium for Future Technology Creating Better Human Health and society, Interdisciplinary Science and Engineering in Health Systems and Medial Anthropology: The Points of Glocal View  2020.1.22 

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    Event date： 2020.1.21 - 2020.1.22

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  • 対応能力を欠くと判断される人にとっての「最善の利益」の要素に関する考察

    日笠 晴香

    京都生命倫理研究会  2020.12.12 

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Awards

  • 第7回スミセイ女性研究者奨励賞

    2014.2  

    日笠 晴香

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Research Projects

  • Further clarification and consideration of what constitutes the best interests of an incompetent person

    Grant number：19K00006  2019.04 - 2022.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)

    HIKASA Haruka

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    Grant amount：\3900000 （ Direct expense: \3000000 、 Indirect expense：\900000 ）

    The study considered the ‘best interests’ of the incompetent person and clarified the followings; (1) the various semantic contents of interests according to the status of retained abilities and functions, and the different contexts in which the components of ‘best interests’ in the theoretical framework of general surrogate decision-making standards are captured, (2) the extent to which the current preferences of the incompetent person can be given priority over the best interests based on objective judgments, (3) the factors which people involved in the care of people with dementia have considered and emphasized in medical care and other decision-making for people with dementia.

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  • 意思決定における自律と最善の利益に関する臨床倫理的研究

    2014.04 - 2017.03

    日本学術振興会  特別研究員奨励費 

    鈴木(日笠) 晴香

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    Grant type：Competitive

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  • 〈人格〉概念の考察に基づく意思決定プロセス研究――臨床倫理の視点から

    2010.04 - 2014.03

    日本学術振興会  特別研究員奨励費 

    鈴木(日笠) 晴香

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    Grant type：Competitive

    (2012年度は出産・育児のため申請保留。）

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Class subject in charge

  • Introduction to Human Care Innovation （2024academic year） Prophase  - 金5～6

  • Advanced Internship for Interdisciplinary Medical Sciences and Engineering （2024academic year） Year-round  - その他

  • Technical English for Interdisciplinary Medical Sciences and Engineering （2024academic year） Late  - その他

  • Introduction to Interdisciplinary Science and Engineering in Health Systems （2024academic year） Prophase  - 火1～2

  • Research Works for Interdisciplinary Medical Sciences and Engineering （2024academic year） Year-round  - その他

  • Research Works for Interdisciplinary Medical Sciences and Engineering （2024academic year） Year-round  - その他

  • Interdisciplinary Science and Engineering in Health Systems （2024academic year） Prophase  - 火5～6

  • Ethics General （2024academic year） Prophase  - 金3～4

  • Advanced Hospital Practice （2024academic year） Prophase  - その他

  • Technical Writing and Presentation （2024academic year） Late  - その他

  • Bioethics （2024academic year） special  - その他

  • Advanced Study of Research Ethics and Law （2024academic year） Prophase  - その他

  • Clinical Thanatology （2024academic year） Fourth semester  - 金5～6

  • Clinical Thanatology 1 （2024academic year） Prophase  - 水3～4

  • Clinical Thanatology 2 （2024academic year） Late  - 水3～4

  • Introduction to Clinical Thanatology （2024academic year） Second semester  - 木3～4

  • Advanced Study in Clinical Thanatology （2024academic year） Prophase  - その他

  • Introduction to Human Care Innovation （2023academic year） Prophase  - 金5～6

  • Advanced Internship for Interdisciplinary Medical Sciences and Engineering （2023academic year） Year-round  - その他

  • Technical English for Interdisciplinary Medical Sciences and Engineering （2023academic year） Late  - その他

  • Introduction to Interdisciplinary Science and Engineering in Health Systems （2023academic year） Prophase  - 金3～4

  • Research Works for Interdisciplinary Medical Sciences and Engineering （2023academic year） Year-round  - その他

  • Research Works for Interdisciplinary Medical Sciences and Engineering （2023academic year） Year-round  - その他

  • Ethics General （2023academic year） Prophase  - 火7～8

  • Technical Writing and Presentation （2023academic year） Late  - その他

  • Bioethics （2023academic year） special  - その他

  • Advanced Study of Research Ethics and Law （2023academic year） Prophase  - その他

  • Humanistic　gerontology （2023academic year） Summer concentration  - その他

  • Clinical Thanatology （2023academic year） Fourth semester  - 金5～6

  • Clinical Thanatology 1 （2023academic year） Prophase  - 水3～4

  • Clinical Thanatology 2 （2023academic year） Late  - 水3～4

  • Introduction to Clinical Thanatology （2023academic year） Second semester  - 木3～4

  • Introduction to Clinical Thanatology （2023academic year） Fourth semester  - 木3～4

  • Advanced Study in Clinical Thanatology （2023academic year） Prophase  - その他

  • Introduction to Human Care Innovation （2022academic year） Prophase  - 金5～6

  • Advanced Internship for Interdisciplinary Medical Sciences and Engineering （2022academic year） Year-round  - その他

  • Technical English for Interdisciplinary Medical Sciences and Engineering （2022academic year） Late  - その他

  • Technical English for Interdisciplinary Medical Sciences and Engineering （2022academic year） Late  - その他

  • Introduction to Interdisciplinary Science and Engineering in Health Systems （2022academic year） Prophase  - 金3～4

  • Research Works for Interdisciplinary Medical Sciences and Engineering （2022academic year） Year-round  - その他

  • General Exercises for Interdisciplinary Medical Sciences and Engineering （2022academic year） Late  - その他

  • Introduction to Interdisciplinary Science and Engineering in Health Systems I （2022academic year） Prophase  - 不開講

  • Ethics General （2022academic year） Prophase  - 火3～4

  • Advanced Hospital Practice （2022academic year） Prophase  - 不開講

  • Advanced Hospital Practice （2022academic year） Prophase  - その他

  • Practical Internship （2022academic year） Year-round  - その他

  • Technical Writing and Presentation （2022academic year） Late  - その他

  • Technical Writing and Presentation （2022academic year） Late  - その他

  • Bioethics （2022academic year） special  - その他

  • Advanced Study of Research Ethics and Law （2022academic year） Prophase  - その他

  • Study on Life and death Ⅱ （2022academic year） Second semester  - 水3～4

  • Clinical Thanatology （2022academic year） Fourth semester  - 金5～6

  • Clinical Thanatology 1 （2022academic year） Prophase  - 水3～4

  • Clinical Thanatology 2 （2022academic year） Late  - 水3～4

  • Introduction to Clinical Thanatology （2022academic year） Second semester  - 金3～4

  • Advanced Study in Clinical Thanatology （2022academic year） Prophase  - その他

  • Cluster Essence （2021academic year） Fourth semester  - 水3～4

  • Cluster Essence （2021academic year） Fourth semester  - 金5～6

  • Introduction to Human Care Innovation （2021academic year） Prophase  - 金5～6

  • Advanced Internship for Interdisciplinary Medical Sciences and Engineering （2021academic year） Year-round  - その他

  • Technical English for Interdisciplinary Medical Sciences and Engineering （2021academic year） Late  - その他

  • Technical English for Interdisciplinary Medical Sciences and Engineering （2021academic year） Late  - その他

  • Introduction to Interdisciplinary Science and Engineering in Health Systems （2021academic year） Prophase  - 金3～4

  • Research Works for Interdisciplinary Medical Sciences and Engineering （2021academic year） Year-round  - その他

  • General Exercises for Interdisciplinary Medical Sciences and Engineering （2021academic year） Late  - その他

  • Interdisciplinary Science and Engineering in Health Systems （2021academic year） Prophase  - 火7～8

  • Introduction to Interdisciplinary Science and Engineering in Health Systems I （2021academic year） Prophase  - その他

  • Ethics General （2021academic year） Prophase  - 火3～4

  • Advanced Hospital Practice （2021academic year） Prophase  - その他

  • Advanced Hospital Practice （2021academic year） Prophase  - その他

  • Practical Internship （2021academic year） Year-round  - その他

  • Technical Writing and Presentation （2021academic year） Late  - その他

  • Technical Writing and Presentation （2021academic year） Late  - その他

  • Bioethics （2021academic year） special  - その他

  • Advanced Study of Research Ethics and Law （2021academic year） Prophase  - その他

  • Clinical Thanatology 1 （2021academic year） Prophase  - 水3～4

  • Clinical Thanatology 2 （2021academic year） Late  - 水3～4

  • Introduction to Clinical Thanatology （2021academic year） Second semester  - 金3～4

  • Introduction to Clinical Thanatology （2021academic year） Third semester  - 金3～4

  • Advanced Study in Clinical Thanatology （2021academic year） Prophase  - その他

  • Cluster Essence （2020academic year） Fourth semester  - 水3,水4

  • Cluster Essence （2020academic year） Fourth semester  - 金5,金6

  • Advanced Internship for Interdisciplinary Medical Sciences and Engineering （2020academic year） Year-round  - その他

  • Technical English for Interdisciplinary Medical Sciences and Engineering （2020academic year） Late  - その他

  • Research Works for Interdisciplinary Medical Sciences and Engineering （2020academic year） Year-round  - その他

  • General Exercises for Interdisciplinary Medical Sciences and Engineering （2020academic year） Late  - その他

  • Introduction to Interdisciplinary Science and Engineering in Health Systems I （2020academic year） Prophase  - 金3,金4

  • Advanced Hospital Practice （2020academic year） Prophase  - その他

  • Practical Internship （2020academic year） Year-round  - その他

  • Technical Writing and Presentation （2020academic year） Late  - その他

  • Bioethics （2020academic year） special  - その他

  • Advanced Study of Research Ethics and Law （2020academic year） Prophase  - その他

  • Clinical Thanatology 1 （2020academic year） Prophase  - 水3,水4

  • Clinical Thanatology 2 （2020academic year） Late  - 水3,水4

  • Introduction to Clinical Thanatology （2020academic year） Second semester  - 金3,金4

  • Advanced Study in Clinical Thanatology （2020academic year） Prophase  - その他

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