Papers - Otsuka Motoyuki
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Absence of tyrosine kinase mutations in Japanese colorectal cancer patients Reviewed
R-X Shao, N. Kato, L-J Lin, R. Muroyama, M. Moriyama, T. Ikenoue, H. Watabe, M. Otsuka, B. Guleng, M. Ohta, Y. Tanaka, S. Kondo, N. Dharel, J-H Chang, H. Yoshida, T. Kawabe, M. Omata
ONCOGENE 26 ( 14 ) 2133 - 2135 2007.3
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Nucleotide change of codon 38 in the X gene of hepatitis B virus genotype C is associated with an increased risk of hepatocellular carcinoma Reviewed
Ryosuke Muroyama, Naoya Kato, Haruhiko Yoshida, Motoyuki Otsuka, Masaru Moriyama, Yue Wang, Run-Xuan Shao, Narayan Dharel, Yasuo Tanaka, Miki Ohta, Ryosuke Tateishi, Shuichiro Shiina, Masashi Tatsukawa, Kenichi Fukai, Fumio Imazeki, Osamu Yokosuka, Yasushi Shiratori, Masao Omata
JOURNAL OF HEPATOLOGY 45 ( 6 ) 805 - 812 2006.12
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Hepatitis C virus core protein is a potent inhibitor of RNA silencing-based antiviral response Reviewed
Y Wang, N Kato, A Jazag, N Dharel, M Otsuka, H Taniguchi, T Kawabe, M Omata
GASTROENTEROLOGY 130 ( 3 ) 883 - 892 2006.3
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Identifying genes with differential expression in gemcitabine-resistant pancreatic cancer cells using comprehensive transcriptome analysis Reviewed
Y Nakai, M Otsuka, Y Hoshida, M Tada, Y Komatsu, T Kawabe, M Omata
ONCOLOGY REPORTS 14 ( 5 ) 1263 - 1267 2005.11
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Large-scale search of single nucleotide polymorphisms for hepatocellular carcinoma susceptibility genes in patients with hepatitis C Reviewed
N Kato, GJ Ji, Y Wang, M Baba, Y Hoshida, M Otsuka, H Taniguchi, M Moriyama, N Dharel, T Goto, RX Shao, T Matsuura, K Ishii, S Shiina, T Kawabe, M Muramatsu, M Omata
HEPATOLOGY 42 ( 4 ) 846 - 853 2005.10
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NF-kappa B and ERK-signaling pathways contribute to the gene expression induced by cag PAI-positive-Helicobacter pylori infection Reviewed
Wataru Shibata, Yoshihiro Hirata, Haruhiko Yoshida, Motoyuki Otsuka, Yujin Hoshida, Keiji Ogura, Shin Maeda, Tomoya Ohmae, Ayako Yanai, Yuzo Mitsuno, Naohiko Seki, Takao Kawabe, Masao Omata
WORLD JOURNAL OF GASTROENTEROLOGY 11 ( 39 ) 6134 - 6143 2005.10
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No mutations in the tyrosine kinases of human hepatic, pancreatic, and gastric cancer cell lines Reviewed
RX Shao, M Otsuka, N Kato, JH Chang, R Muroyama, H Taniguchi, M Moriyama, Y Wang, T Kawabe, M Omata
JOURNAL OF GASTROENTEROLOGY 40 ( 9 ) 918 - 918 2005.9
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Hepatitis C virus core protein and hepatitis activity are associated through transactivation of interleukin-8 Reviewed
Y Hoshida, N Kato, H Yoshida, Y Wang, M Tanaka, T Goto, M Otsuka, H Taniguchi, M Moriyama, F Imazeki, O Yokosuka, T Kawabe, Y Shiratori, M Omata
JOURNAL OF INFECTIOUS DISEASES 192 ( 2 ) 266 - 275 2005.7
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Interaction between the HCVNS3 protein and the host TBK1 protein leads to inhibition of cellular antiviral responses Reviewed
M Otsuka, N Kato, M Moriyama, H Taniguchi, Y Wang, N Dharel, T Kawabe, M Omata
HEPATOLOGY 41 ( 5 ) 1004 - 1012 2005.5
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Hepatic gene expression profiles associated with fibrosis progression and hepatocarcinogenesis in hepatitis C patients Reviewed
Run-Xuan Shao, Yujin Hoshida, Motoyuki Otsuka, Naoya Kato, Ryosuke Tateishi, Takuma Teratani, Shuichiro Shiina, Hiroyoshi Taniguchi, Masaru Moriyama, Takao Kawabe, Masao Omata
WORLD JOURNAL OF GASTROENTEROLOGY 11 ( 13 ) 1995 - 1999 2005.4
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Vitamin K2 binds 17 beta-hydroxysteroid dehydrogenase 4 and modulates estrogen metabolism Reviewed
M Otsuka, N Kato, T Ichimura, S Abe, Y Tanaka, H Taniguchi, Y Hoshida, M Moriyama, Y Wang, RX Shao, D Narayan, R Muroyama, F Kanai, T Kawabe, T Isobe, M Omata
LIFE SCIENCES 76 ( 21 ) 2473 - 2482 2005.4
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Acyclic retinoid inhibits human hepatoma cell growth by suppressing fibroblast growth factor-mediated signaling pathways Reviewed
RX Shao, M Otsuka, N Kato, H Taniguchi, Y Hoshida, M Moriyama, T Kawabe, M Omata
GASTROENTEROLOGY 128 ( 1 ) 86 - 95 2005.1
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A simple combination of serum type IV collagen and prothrombin time to diagnose cirrhosis in patients with chronic active hepatitis C Reviewed
Y Qiu, YJ Hoshida, N Kato, M Moriyama, M Otsuka, H Taniguchi, T Kawabe, M Omata
HEPATOLOGY RESEARCH 30 ( 4 ) 214 - 220 2004.12
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Genes associated with human hepatocellular carcinoma cell chemosensitivity to 5-fluorouracil plus interferon-alpha combination chemotherapy Reviewed
M Moriyama, Y Hoshida, N Kato, M Otsuka, H Yoshida, T Kawabe, M Omata
INTERNATIONAL JOURNAL OF ONCOLOGY 25 ( 5 ) 1279 - 1287 2004.11
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Vitamin K-2 inhibits the growth and invasiveness of hepatocellular carcinoma cells via protein kinase A activation Reviewed
M Otsuka, N Kato, RX Shao, Y Hoshida, H Ijichi, Y Koike, H Taniguchi, M Moriyama, Y Shiratori, T Kawabe, M Omata
HEPATOLOGY 40 ( 1 ) 243 - 251 2004.7
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UDP-glucuronosyltransferase 1A7 genetic polymorphisms are associated with hepatocellular carcinoma in Japanese patients with hepatitis C virus infection Reviewed
Y Wang, N Kato, Y Hoshida, M Otsuka, H Taniguchi, M Moriyama, S Shiina, T Kawabe, YM Ito, M Omata
CLINICAL CANCER RESEARCH 10 ( 7 ) 2441 - 2446 2004.4
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Smad4-independent regulation of p21/WAF1 by transforming growth factor-beta Reviewed
H Ijichi, M Otsuka, K Tateishi, T Ikenoue, T Kawakami, F Kanai, Y Arakawa, N Seki, K Shimizu, K Miyazono, T Kawabe, M Omata
ONCOGENE 23 ( 5 ) 1043 - 1051 2004.2
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Hepatitis C virus core protein upregulates transforming growth factor-beta 1 transcription Reviewed
H Taniguchi, N Kato, M Otsuka, T Goto, H Yoshida, Y Shiratori, M Omata
JOURNAL OF MEDICAL VIROLOGY 72 ( 1 ) 52 - 59 2004.1
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Antiapoptotic regulation by hepatitis C virus core protein through up-regulation of inhibitor of caspase-activated DNase Reviewed
R Sacco, T Tsutsumi, R Suzuki, M Otsuka, H Aizaki, S Sakamoto, M Matsuda, N Seki, Y Matsuura, T Miyamura, T Suzuki
VIROLOGY 317 ( 1 ) 24 - 35 2003.12
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Comparing gene expression profiles in human liver, gastric, and pancreatic tissues using full-length-enriched cDNA libraries Reviewed
M Otsuka, M Arai, M Mori, M Kato, N Kato, O Yokosuka, T Ochiai, M Takiguchi, M Omata, N Seki
HEPATOLOGY RESEARCH 27 ( 1 ) 76 - 82 2003.9