Updated on 2024/12/05

写真a

 
IZUMI Minoru
 
Organization
Faculty of Environmental, Life, Natural Science and Technology Professor
Position
Professor
External link

Degree

  • Ph.D. ( 2001.12   Osaka University )

  • Ph.D. ( 1998.3   Osaka Prefecture University )

Research Interests

  • 糖鎖工学

  • コンビナトリアルケミストリー

  • 有機合成化学

  • ケミカルバイオロジー

  • Organic Chemistry

  • Chemical Biology

  • Combinatrical Chemistry

  • Carbohydrate Chemistry

  • 農薬化学

Research Areas

  • Environmental Science/Agriculture Science / Landscape science

  • Environmental Science/Agriculture Science / Environmental agriculture

  • Nanotechnology/Materials / Structural organic chemistry and physical organic chemistry

  • Life Science / Bioorganic chemistry

  • Nanotechnology/Materials / Nanomaterials

▼display all

Education

  • Osaka University   大学院理学研究科   博士後期課程 化学専攻

    1998.4 - 2001.12

      More details

    Country: Japan

    researchmap

  • Osaka Prefecture University   大学院農学研究科   博士前期課程 農芸化学専攻

    1996.4 - 1998.3

      More details

  • Osaka Prefecture University   農学部   農芸化学科

    1992.4 - 1996.3

      More details

    Country: Japan

    researchmap

Research History

  • Okayama University   学術研究院環境生命自然科学学域   Professor

    2023.4

      More details

    Country:Japan

    researchmap

  • Osaka Prefecture University   Graduate School of Life and Environmental Sciences Division of Applied Life Sciences

    2021.4

      More details

    Country:Japan

    researchmap

  • Okayama University   学術研究院環境生命科学学域   Associate Professor

    2021.4 - 2023.3

      More details

    Country:Japan

    researchmap

  • Okayama University   The Graduate School of Environmental and Life Science   Associate Professor

    2014.4 - 2023.3

      More details

  • Dalian Polytechnic University

    2011.5

      More details

    Country:China

    researchmap

▼display all

Professional Memberships

  • THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH

      More details

  • THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN

      More details

  • JAPANESE SOCIETY FOR CHEMICAL BIOLOGY

      More details

  • JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY

      More details

  • THE CHEMICAL SOCIETY OF JAPAN

      More details

Committee Memberships

  • 日本農芸化学会中四国支部   支部参与  

    2019.4 - 2023.3   

      More details

    Committee type:Academic society

    researchmap

  • Visionaryシンポジウム「天然物化学」第2回 実行委員会   実行委員  

    2018 - 2021   

      More details

    Committee type:Academic society

    researchmap

  • 日本農芸化学会2014年度大会 実行委員会   実行委員  

    2014 - 2015.3   

      More details

    Committee type:Academic society

    researchmap

  • 天然物化学談話会   世話人  

    2013.10 - 2017.10   

      More details

    Committee type:Academic society

    researchmap

  • 日本農薬学会第37回大会実行委員会   実行委員  

    2011 - 2012.3   

      More details

    Committee type:Academic society

    researchmap

▼display all

 

Papers

  • Synthesis of the A/D/E-ring Core Compounds of Maoecrystal V†. Reviewed International journal

    Hiroki Asao, Yasuharu Shimasaki, Ayaka Sasaki, Shunki Katayama, Kousuke Ida, Masaaki Kotake, Eriko Sato, Yuki Sato, Taiki Ishimoto, Minoru Izumi, Christopher J Vavricka, Shigefumi Kuwahara, Hiromasa Kiyota

    Bioscience, biotechnology, and biochemistry   88 ( 7 )   733 - 741   2024.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Synthesis of the A/D/E-ring core compounds of maoecrystal V was achieved. The key Diels-Alder reactions between tricyclic α-methylene lactones and Kitahara-Danishefsky dienes afforded the spirocyclic core compounds in a regioselective and stereoselective manner.

    DOI: 10.1093/bbb/zbae049

    PubMed

    researchmap

  • Fischer Glycosidation Using Organotitanium Catalyst ORGATIX Reviewed

    Minoru Izumi, Nana Yanagida, Keita Kato, Mako Matsushita

    HETEROCYCLES   106 ( 8 )   1309 - 1309   2023.8

     More details

    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:The Japan Institute of Heterocyclic Chemistry  

    DOI: 10.3987/com-23-14866

    researchmap

  • Synthesis of the C/D/E-ring core compound of maoecrystal V Reviewed

    Shunki Katayama, Mitsuki Nishimoto, Tatsuya Ura, Taiki Ishimoto, Kousuke Ida, Yuki Sato, Christopher J. Vavricka, Minoru Izumi, Hiromasa Kiyota

    Synthetic Communications   53 ( 10 )   708 - 712   2023.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Informa UK Limited  

    DOI: 10.1080/00397911.2023.2191853

    researchmap

  • Synthesis of the oxazolidinone fragment of thelepamide Reviewed

    Naoki Ashida, Kousuke Ida, Yumi Koide, Christopher J. Vavricka, Minoru Izumi, Hiromasa Kiyota

    NATURAL PRODUCT RESEARCH   36 ( 7 )   1686 - 1692   2022.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:TAYLOR & FRANCIS LTD  

    Thelepamide, an unique ketide-amino acid isolated from a marine annelid wormThelepus crispus, has a unique oxazolidinone ring derived from cysteine, glycine and valine. Rareness in nature as well as promising bioactive possibility make the oxazolidinone ring an attractive synthetic target. The hydroxy oxazolidinone fragment of thelepamide was prepared by acid-catalysedN,O-acetal formation between a ketoamide and formaldehyde. Lactone-carbonyl selective isopropyl addition to an oxazilidine-dione under Grignard conditions also forms the target compound.

    DOI: 10.1080/14786419.2020.1809398

    Web of Science

    researchmap

  • Evaluation of an improved antinematodal assay against the plantparasitic nematode Bursaphelenchus xylophilus and its application to an antinematodal activity study of synthetic 4-methylumbelliferyl glycoside Reviewed

    Minoru Izumi, Kentaro Nakamura, Ayuko Ishizaka, Hiromasa Kiyota, Shuhei Nakajima

    Nematological Research   51 ( 2 )   33 - 36   2021.12

     More details

    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    researchmap

▼display all

Books

  • コンビナトリアルサイエンスの新展開

    シーエムシー出版(東京)  2002 

     More details

MISC

  • NAADPを基本分子としたバーチャルスクリーニングによる分子プローブの開発とその後 : コンピューターによる研究の効率化

    泉 実

    化学と生物 : 日本農芸化学会会誌 : 生命・食・環境   55 ( 6 )   375 - 377   2017.6

     More details

    Authorship:Lead author, Last author, Corresponding author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:日本農芸化学会 ; 1962-  

    DOI: 10.1271/kagakutoseibutsu.55.375

    CiNii Article

    CiNii Books

    researchmap

    Other Link: http://search.jamas.or.jp/link/ui/2017252563

  • 半強制的な反復学習による基礎科目の徹底教育

    泉 実, 村田芳行

    岡山大学農学部学術報告   ( 106 )   1 - 3   2017

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)  

    researchmap

  • 半強制的な反復学習による専門基礎科目の徹底教育 Invited

    泉 実

    第19回桃太郎フォーラム報告書   106 - 112   2017

     More details

    Authorship:Lead author, Last author, Corresponding author   Language:English   Publishing type:Meeting report  

    researchmap

  • 1P-042 Functional analysis of galactofuranosyltransferase (GfsA) in Aspergillus nidulans

    Katafuchi Yukako, Ekino Keisuke, Izumi Minoru, Takegawa Kaoru, Goto Masatoshi, Oka Takuji

    67   99 - 100   2015

  • 生細胞内でパラジウム触媒反応? Invited Reviewed

    泉 実

    化学   66 ( 9 )   63 - 64   2011

     More details

    Authorship:Lead author, Last author, Corresponding author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

    researchmap

▼display all

Presentations

  • 色素タグによる糖質誘導体の効率的合成

    松下 真子, 西 結衣子, 柳田 菜名, 泉 実

    2024年日本化学会中国四国支部大会 岡山大会  2024.11.16 

     More details

    Event date: 2024.11.16 - 2024.11.17

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • ポリインを有する糖質誘導体の合成とその抗線虫活性の検討

    柳田 菜名, 西 結衣子, 藤井 保乃歌, 松下 真子, 泉 実

    2024年日本化学会中国四国支部大会 岡山大会  2024.11.16 

     More details

    Event date: 2024.11.16 - 2024.11.17

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • 酸化的環化反応による複素環式化合物の合成とその抗線虫活性の検討

    西 結衣子, 梅村 優志, 柳田 菜名, 泉 実

    2024年日本化学会中国四国支部大会 岡山大会  2024.11.16 

     More details

    Event date: 2024.11.16 - 2024.11.17

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • 抗マツノザイセンチュウ薬剤探索を指向したポリイン骨格を有する化合物の合成

    柳田菜名, 藤井保乃歌, 松下真子, 泉 実

    第11回(2023年)日本化学会中国四国支部大会 山口大会  2023.11.11 

     More details

    Event date: 2023.11.11 - 2023.11.12

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

  • 化合物の色素タグによる糖質誘導体の効率的合成

    松下真子, 溝手章子, 柳田菜名, 泉 実

    第11回(2023年)日本化学会中国四国支部大会 山口大会  2023.11.11 

     More details

    Event date: 2023.11.11 - 2023.11.12

    Language:Japanese   Presentation type:Poster presentation  

    researchmap

▼display all

Industrial property rights

  • 表面修飾された金ナノ粒子及びその製造方法

    芝上基成, 泉 実

     More details

    Applicant:国立研究開発法人産業技術総合研究所

    Application no:特願2003-181957  Date applied:2003.6.26

    Announcement no:特開2005-015846  Date announced:2005.1.20

    3855057

    researchmap

  • 反応性有機基を有する金粒子

    芝上基成, 高木俊之, 泉 実

     More details

    Applicant:国立研究開発法人産業技術総合研究所

    Application no:特願2002-362679  Date applied:2002.12.13

    Announcement no:特開2004-189701  Date announced:2004.7.8

    researchmap

Awards

  • 技術奨励賞

    2019.7   岡山工学振興会  

    泉 実

     More details

  • 2010年度日本農芸化学会中四国支部奨励賞

    2010.9   日本農芸化学会中四国支部   カルシウム情報伝達系解明のための分子プローブの合成とその応用

    泉 実

     More details

    Country:Japan

    researchmap

Research Projects

  • Synthetic studies of biologically active natural products with unique structures ~ developments of new drug leads

    Grant number:17K07772  2017.04 - 2020.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Kiyota Hiromasa

      More details

    Grant amount:\4810000 ( Direct expense: \3700000 、 Indirect expense:\1110000 )

    Natural organic compounds and derivatives having a unique structure and biological activity have been used as pesticides, medicines, or prototypes thereof. In this study, we succeeded in isolating novel structures of terpenoids with antitumor activity etc. form the Chinese yew, mangrove, and herb. Furthermore, we conducted synthetic studies on the plant component maoecrystal V, the antibiotic enacyloxins, the marine substances telepamide, clionnamines, greensporones, sanctolide A, cortistatin A, etc., and achieved total synthesis or the synthesis of key intermediates. We have also succeeded in synthesizing sulfosialic acids, which are lead candidates for antiinfluenza drugs.

    researchmap

  • Development of agrochemical and pharmaceutical lead compounds based on the search and total synthesis of natural compounds with a unique structure and biological activity

    Grant number:25450144  2013.04 - 2016.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Kiyota Hiromasa, IZUMI Minoru, UCHIDA Takafumi, USUI Takeo, KAWATANI Makoto, SHI Qinq-Wen

      More details

    Grant amount:\5330000 ( Direct expense: \4100000 、 Indirect expense:\1230000 )

    Naturally occurring organic compounds of low molecular weight and the derivatives have been used as agrochemicals and/or medicines to date. We have achieved the isolation and structure elucidation of several novel terpenoids and polyketides from plants such as a yew, a manglobe, herbs etc. We have also succeeded in the total or partial synthesis of biologically active natural products such as enacyloxins and spirofungins (antibiotics), thelepamide and clionamine D (marine natural products), maoecrystal V and echinopine A (herbal products), pyriculariol (a plant pathogenic compound) etc. 2,3-Difluorosialic acid, synthesized with the aim to develop a new anti-influenza agent, inhibited the sialidase of Tamiflu-resistant strain.

    researchmap

  • 特徴ある糖質の機能を生かした健康バイオ産業の創出(高松エリア)

    2008 - 2011

    文部科学省  都市エリア産学官連携促進事業 

      More details

    Authorship:Collaborating Investigator(s) (not designated on Grant-in-Aid) 

    researchmap

  • 金微粒子を用いたChemicalFishing法の確立と糖鎖パーティクルの創製

    Grant number:03J01535  2003

    日本学術振興会  科学研究費助成事業  特別研究員奨励費

    泉 実

      More details

    Grant amount:\1100000 ( Direct expense: \1100000 )

    researchmap

 

Class subject in charge

  • Natural Product Chemistry (2024academic year) Prophase  - 金3~4

  • Seminar in Applied Natural Product Chemistry (2024academic year) Prophase  - その他

  • Seminar in Applied Natural Product Chemistry (2024academic year) Late  - その他

  • Seminar in Applied Natural Product Chemistry (2024academic year) Year-round  - その他

  • Current Topics in Synthetic and Medicinal Chemistry (2024academic year) Late  - その他

▼display all

 

Social Activities

  • 公益財団法人八雲環境科学振興財団研究レポート集第22号

    Role(s):Report writing

    公益財団法人八雲環境科学振興財団  2021.11

     More details

    Type:Promotional material

    researchmap

  • 公益財団法人岡山工学振興会年報30号

    Role(s):Report writing

    公益財団法人岡山工学振興会  2021.10.29

     More details

    Type:Promotional material

    researchmap