Updated on 2024/10/18

写真a

 
WATANABE Takaichi
 
Organization
Faculty of Environmental, Life, Natural Science and Technology Associate Professor
Position
Associate Professor
Profile

学歴
2005年3月 岡山県立倉敷南高等学校 卒業
2009年3月 岡山大学環境理工学部環境物質工学科 卒業
2011年3月 岡山大学大学院環境学研究科資源循環学専攻 修了
2014年3月 岡山大学大学院自然科学研究科機能分子化学専攻 修了 博士(工学)

(2012年5月–2013年8月 Imperial College London, Department of Chemical Engineering, Erasmus奨学生)

職歴
2013年4月ー2014年3月  日本学術振興会 特別研究員(DC2)
2014年4月ー2014年12月 日本学術振興会 特別研究員(PD) 
2015年1月ー2016年3月 東京大学 生産技術研究所 特任研究員
2016年4月ー2017年3月 東京大学 生産技術研究所 協力研究員
2016年4月ー2021年3月 岡山大学大学院自然科学研究科応用化学専攻 助教
2021年4月ー2023年3月 岡山大学学術研究院自然科学学域 助教
2021年5月ー2023年3月 岡山大学学術研究院自然科学学域 研究准教授
2023年4月ー2024年3月 岡山大学学術研究院環境生命自然科学学域 助教(研究准教授)(改組のため)
2022年5月ー2024年3月 アーヘン工科大学 客員研究員 (兼任)
2024年4月ー現在      岡山大学学術研究院環境生命自然科学学域 准教授

Personal web page
https://sites.google.com/s.okayama-u.ac.jp/takaichiwatanabe/home

External link

Degree

  • 博士(工学) ( 岡山大学 )

Research Interests

  • Microfluidics

  • Micro chemical process

  • Polymeric microsphere

  • Soft Matter

Research Areas

  • Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Chemical reaction and process system engineering

  • Life Science / Biomedical engineering

  • Life Science / Biomaterials

  • Nanotechnology/Materials / Polymer chemistry

  • Nanotechnology/Materials / Polymer materials

Education

  • Okayama University   自然科学研究科   機能分子化学専攻 博士後期課程

    2013.4 - 2014.3

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  • Okayama University   環境学研究科   資源循環学専攻 博士後期課程

    2011.4 - 2013.3

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  • Okayama University   環境学研究科   資源循環学専攻 博士前期課程

    2009.4 - 2011.3

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  • Okayama University   環境理工学部   物質工学科

    2005.4 - 2009.3

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  • 岡山県立倉敷南高等学校    

    2002.4 - 2005.3

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    Country: Japan

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Research History

  • Okayama University   学術研究院環境生命自然科学学域   Associate Professor

    2024.4

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    Country:Japan

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  • Okayama University   学術研究院環境生命自然科学学域

    2023.4 - 2024.3

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    Country:Japan

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  • RWTH Aachen University Visiting Scientist

    2022.5 - 2024.3

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    Country:Germany

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  • Okayama University   Graduate School of Natural Science and Technology   Research Associate Professor

    2021.5 - 2023.3

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  • Okayama University   Graduate School of Natural Science and Technology   Assistant Professor

    2021.4 - 2023.3

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  • Okayama University   Graduate School of Natural Science and Technology   Assistant Professor

    2016.4 - 2021.3

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  • The University of Tokyo   Institute of Industrial Science

    2015.1 - 2016.3

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  • 日本学術振興会特別研究員PD

    2014.4 - 2014.12

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  • 日本学術振興会特別研究員DC2

    2013.4 - 2014.3

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Professional Memberships

  • THE SOCIETY OF POLYMER SCIENCE, JAPAN

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  • THE TEXTILE MACHINERY SOCIETY OF JAPAN

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  • THE SOCIETY OF CHEMICAL ENGINEERS, JAPAN

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  • 日本レオロジー学会

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  • 日本化学会 コロイドおよび界面科学部会

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Committee Memberships

  • 化学工学会   材料・界面部会 事務局  

    2023.4 - 2025.3   

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    Committee type:Academic society

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  • 化学工学会   第52回秋季大会セッションオーガナイザー  

    2021.9   

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  •   化学工学会中国四国支部 中四国若手CE合宿 代表幹事  

    2021.4 - 2023.3   

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  • 化学工学会   全国若手の会 コアメンバー  

    2021.4 - 2022.3   

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  • 化学工学会   第51回秋季大会 セッションオーガナイザー  

    2020.9   

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  • 第22回化学工学会学生発表会岡山大会   第22回化学工学会学生発表会岡山大会実行委員  

    2020.3   

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  • 化学工学会 材料界面部会   材料化学システム工学討論会2019 幹事  

    2018.10 - 2019.10   

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    Committee type:Academic society

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  • 化学工学会   第50回秋季大会セッションオーガナイザー  

    2018.9   

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  • 化学工学会   反応工学部会マイクロ化学プロセス分科会幹事  

    2018.4   

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  • 第20回高分子ミクロスフェア討論会   運営委員  

    2018.4 - 2018.11   

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  •   第12回中四国若手CE合宿 世話人  

    2018.4 - 2018.9   

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  • 化学工学会   材料化学システム工学討論会2018 副幹事  

    2018.1 - 2018.9   

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  • 化学工学会中国四国支部   中四国若手CE合宿幹事  

    2017.9   

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  • 化学工学会   第49回秋季大会セッションオーガナイザー  

    2017.9   

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  • 化学工学会   高度生産システム検討委員会委員およびファウリング防止エチレン分科会委員  

    2017.7 - 2020.3   

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  • 岡山地区化学工学懇話会   幹事  

    2016.5   

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  • 化学工学会   材料界面部会ソフトマター工学分科会幹事  

    2016.4   

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Papers

  • Structure and Rheology of Carboxymethylcellulose in Polar Solvent Mixtures Reviewed

    Carbohydrate Polymers   2024.5

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  • Engineering Interconnected Open-Porous Particles via Microfluidics Using Bijel Droplets as Structural Templates Reviewed

    Mina Masaoka, Hiroaki Ishida, Takaichi Watanabe, Tsutomu Ono

    Langmuir   40 ( 15 )   8074 - 8082   2024.4

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:American Chemical Society (ACS)  

    DOI: 10.1021/acs.langmuir.3c04017

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  • Controlled mechanical properties of poly(ionic liquid)-based hydrophobic ion gels by the introduction of alumina nanoparticles with different shapes Reviewed

    Yuna Mizutani, Takaichi Watanabe, Carlos Gonzalez Lopez, Tsutomu Ono

    Soft Matter   2024.1

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Royal Society of Chemistry (RSC)  

    Ionic-liquid gels, also known as ion gels, have gained considerable attention due to their high ionic conductivity and CO2 absorption capacity. However, their low mechanical strength has hindered their practical...

    File: d3sm01626a.pdf

    DOI: 10.1039/d3sm01626a

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  • Toughening of poly(ionic liquid)-based ion gels with cellulose nanofibers as a sacrificial network Reviewed

    Takaichi Watanabe, Emiho Oe, Yuna Mizutani, Tsutomu Ono

    Soft Matter   19   2745 - 2754   2023.3

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Royal Society of Chemistry (RSC)  

    A tough ion gel composed of TEMPO-oxidized cellulose nanofiber (TOCNF) and a poly(ionic liquid) double network was developed.

    File: Oe_SoftMatter.2023.pdf

    DOI: 10.1039/d3sm00112a

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  • Microfluidic Production of Monodisperse Biopolymer Microcapsules for Latent Heat Storage Reviewed

    Takaichi Watanabe, Yuko Sakai, Naomi Sugimori, Toshinori Ikeda, Masayuki Monzen, Tsutomu Ono

    ACS Materials Au   2   250 - 259   2022.1

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    File: acsmaterialsau.1c00068.pdf

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  • Multilayer Poly(ionic liquid) Microcapsules Prepared by Sequential Phase Separation and Subsequent Photopolymerization in Ternary Emulsion Droplets Reviewed

    Takaichi Watanabe, Yuka Yasuhara, Tsutomu Ono

    ACS Applied Polymer Materials   4 ( 10 )   348 - 356   2021.12

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:American Chemical Society (ACS)  

    DOI: 10.1021/acsapm.1c01315

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  • Preparation of monodisperse poly(methyl methacrylate)/polystyrene composite particles by seeded emulsion polymerization using a sequential flow process Reviewed

    Takaichi Watanabe, Kengo Karita, Midori Manabe, Tsutomu Ono

    Frontiers in Chemical Engieneering   3   62   2021.10

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  • Design of Clickable Ionic Liquid Monomers to Enhance Ionic Conductivity for Main Chain 1,2,3-Triazolium-based Poly(ionic liquid)s Reviewed

    Ruka Hirai, Takaichi Watanabe, Tsutomu Ono

    6 ( 15 )   10030 - 10038   2021.2

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  • Millimeter-thick xenoislet-laden fibers as retrievable transplants mitigate foreign body reactions for long-term glycemic control in diabetic mice Reviewed

    Takaichi Watanabe, Teru Okitsu, Fumisato Ozawa, Shogo Nagata, Hitomi Matsunari, Hiroshi Nagashima, Masaki Nagaya, Hiroki Teramae, Shoji Takeuchi

    Biomaterials   255   120162 - 120162   2020.6

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Elsevier BV  

    DOI: 10.1016/j.biomaterials.2020.120162

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  • Preparation of tough, thermally stable, and water-resistant double-network ion gels consisting of silica nanoparticles/poly(ionic liquid)s through photopolymerisation of an ionic monomer and subsequent solvent removal Reviewed

    Takaichi Watanabe, Ruri Takahashi, Tsutomu Ono

    SOFT MATTER   16 ( 6 )   1572 - 1581   2020.2

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:ROYAL SOC CHEMISTRY  

    We report the preparation of tough, thermally stable, and water-resistant double-network (DN) ion gels, which consist of a partially-clustered silica nanoparticle network and poly(ionic liquid) (PIL) network holding an ionic liquid. Silica nanoparticles/poly([Evim][Tf2N]) DN ion gels are prepared by photo-induced radical polymerisation of [Evim][Tf2N] in a mixture containing silica nanoparticles, [Bmim][Tf2N], ionic liquid based cross-linker [(VIM)(2)C-4][Tf2N](2), and ethyl acetate, followed by subsequent solvent evaporation. Tensile strength measurements show that the mechanical properties of the PIL DN ion gels were higher than those of the PIL single-network (SN) ion gel. A rheological study indicates that an enhancement in mechanical strength of the PIL DN ion gels can be achieved when silica nanoparticles form partial clusters in [Bmim][Tf2N]. The cyclic stress-strain measurement of the PIL DN ion gels shows hysteresis loops, suggesting that the silica nanoparticle clusters rupture and dissipate the loading energy when the PIL DN ion gels undergo a large deformation. The fracture strength and Young's modulus of the PIL DN ion gels increase as the diameter of the silica nanoparticles is decreased. Thermogravimetric analysis measurement shows that the PIL DN ion gel has a high decomposition temperature of approximately 400 degrees C. Moreover, the swelling test shows that the PIL DN ion gel possesses an excellent water-resistant property because of the hydrophobic nature of the PIL backbone. We believe that such tough, thermally stable, and water-resistant PIL DN ion gels can be used as carbon dioxide separation membranes, sensors, and actuators for soft robotics.

    DOI: 10.1039/c9sm02213a

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  • Microfluidic Formation of Hydrogel Microcapsules with a Single Aqueous Core by Spontaneous Cross-Linking in Aqueous Two-Phase System Droplets Reviewed

    Takaichi Watanabe, Ibuki Motohiro, Tsutomu Ono

    LANGMUIR   35 ( 6 )   2358 - 2367   2019.2

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:AMER CHEMICAL SOC  

    We report a simple process to fabricate monodisperse tetra-arm poly(ethylene glycol) (tetra-PEG) hydrogel microcapsules with an aqueous core and a semipermeable hydrogel shell through the formation of aqueous two-phase system (ATPS) droplets consisting of a dextran-rich core and a tetra-PEG macromonomer-rich shell, followed by a spontaneous cross-end coupling reaction of tetra-PEG macromonomers in the shell. Different from conventional techniques, this process enables for the continuous production of hydrogel microcapsules from water-in-oil emulsion droplets under mild conditions in the absence of radical initiators and external stimuli such as heating and ultraviolet light irradiation. We find that rapid cross-end coupling reaction of tetra-PEG macromonomers in ATPS droplets in the range of pH from 7.4 to 7.8 gives hydrogel microcapsules with a kinetically arrested core-shell structure. The diameter and core-shell ratio of the microcapsules can be easily controlled by adjusting flow rates and ATPS compositions. On the other hand, the slow cross-end coupling reaction of tetra-PEG macromonomers in ATPS droplets at pH 7.0 and lower induces structural change from core-shell to Janus during the reaction, which eventually forms hydrogel microparticles with a thermodynamically stable crescent structure. We believe that these hydrogel microparticles with controlled structures can be used in biomedical fields such as cell encapsulation, biosensors, and drug delivery carriers for sensitive biomolecules.

    DOI: 10.1021/acs.langmuir.8b04169

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  • Microfluidic devices for small-angle neutron scattering Reviewed

    Lopez Carlos G, Watanabe Takaichi, Adamo Marco, Martel Anne, Porcar Lionel, Cabral Joao T

    JOURNAL OF APPLIED CRYSTALLOGRAPHY   51   570 - 583   2018.6

  • Microfluidic Approach to the Formation of Internally Porous Polymer Particles by Solvent Extraction Reviewed

    Takaichi Watanabe, Carlos G. Lopez, Jack F. Douglas, Tsutomu Ono, Joao T. Cabral

    LANGMUIR   30 ( 9 )   2470 - 2479   2014.3

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    We report the controlled formation of internally porous polyelectrolyte particles with diameters ranging from tens to hundreds of micrometers through selective solvent extraction using microfluidics. Solvent-resistant microdevices, fabricated by frontal photopolymerization, encapsulate binary polymer (P)/solvent (Si) mixtures by a carrier solvent phase (C) to form plugs with well-defined radii and low polydispersity; the suspension is then brought into contact with a selective extraction solvent (S2) that is miscible with C and Si but not P, leading to the extraction of Si from the droplets. The ensuing phase inversion yields polymer capsules with a smooth surface but highly porous internal structure. Depending on the liquid extraction time scale, this stage can be carried out in situ, within the chip, or ex situ, in an external S2 bath. Bimodal polymer plugs are achieved using asymmetrically inverted T junctions. For this demonstration, we form sodium poly(styrenesulfonate) (P) particles using water (S1), hexadecane (C), and methyl ethyl ketone (S2). We measure droplet extraction rates as a function of drop size and polymer concentration and propose a simple scaling model to guide particle formation. We find that the extraction time required to form particles from liquid droplets does not depend on the initial polymer concentration but is rather proportional to the initial droplet size. The resulting particle size follows a linear relationship with the initial droplet size for all polymer concentrations, allowing for the precise control of particle size. The internal particle porous structure exhibits a polymer density gradient ranging from a dense surface skin toward an essentially hollow core. Average particle porosities between 10 and 50% are achieved by varying the initial droplet compositions up to IS wt % polymer. Such particles have potential applications in functional, optical, and coating materials.

    DOI: 10.1021/la404506b

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  • Manipulation of droplets in a microchannel by ultrasonic vibration for the generation of monodisperse emulsions Reviewed

    Yoshiki OHARA, Shoko SEO, Takefumi KANDA, Kazuki HARITA, Tsutomu ONO, Takaichi WATANABE, Shuichi Wakimoto

    The Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec)   2021   1P2 - K05   2021.6

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    Publishing type:Research paper (international conference proceedings)   Publisher:Japan Society of Mechanical Engineers  

    DOI: 10.1299/jsmermd.2021.1p2-k05

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  • One-pot synthesis of poly(ionic liquid)s with 1,2,3-triazolium-based backbonesviaclickable ionic liquid monomers Reviewed

    Ruka Hirai, Tatsuki Hibino, Takaichi Watanabe, Takashi Teranishi, Tsutomu Ono

    RSC Advances   10 ( 62 )   37743 - 37748   2020.10

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Royal Society of Chemistry (RSC)  

    <p>Clickable ionic liquid monomers realize the one-pot synthesis of ionically conducting poly(ionic liquid)s with 1,2,3-triazolium-based backbones<italic>via</italic>click chemistry.</p>

    DOI: 10.1039/d0ra07948k

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  • Flow synthesis of monodisperse micron-sized polymer particles by heterogeneous polymerization using water-in-oil slug flow with non-ionic surfactant Reviewed

    Takaichi Watanabe, Kengo Karita, Tsutomu Ono

    Colloid and Polymer Science   298   1273 - 1281   2020.7

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  • Microfluidic Preparation of Hydrogel Microcapsules Using Aqueous Two-Phase System Formation in Monodisperse Droplets

    Takaichi WATANABE, Tsutomu ONO

    JAPANESE JOURNAL OF MULTIPHASE FLOW   34 ( 2 )   318 - 325   2020.6

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    Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society for Multiphase Flow  

    DOI: 10.3811/jjmf.2020.t007

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  • Metal Microcapsules Prepared via Electroless Plating at Liquid-Liquid Interface Reviewed

    Toshihiko Tsuneyoshi, Hiroaki Ishida, Yunlong Cui, Takaichi Watanabe, Tsutomu Ono

    Langmuir   35   13311 - 13317   2019.9

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  • Rapid Synthesis of Poly(methyl methacrylate) Particles with High Molecular Weight by Soap-Free Emulsion Polymerization Using Water-in-Oil Slug Flow Reviewed

    Takaichi Watanabe, Kengo Karita, Koki Tawara, Takuya Soga, Tsutomu Ono

    MACROMOLECULAR CHEMISTRY AND PHYSICS   220 ( 9 )   1900021   2019.5

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:WILEY-V C H VERLAG GMBH  

    A flow process for the production of poly(methyl methacrylate) (PMMA) particles is proposed by soap-free emulsion polymerization using a water-in-oil (W/O) slug flow in a microreactor. Thin oil films generated around the dispersed aqueous phase of the W/O slug prevent the prepared particles from adhesion to the microchannel wall, enabling the continuous production of PMMA particles without clogging. The effects of the linear flow rate of the slug flow and the addition of ethanol in the dispersed aqueous phase on the polymerization are evaluated. It is found that increasing the linear flow rate of the slug flow or the addition of ethanol in the dispersed aqueous phase results in PMMA particles with high molecular weight (approximate to 1500 kg mol(-1)) in 20 min reaction time. It is believed that this process would be a promising way to prepare polymer particles with high molecular weight in a short reaction time.

    DOI: 10.1002/macp.201900021

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  • Free-Standing Metal Films Prepared via Electroless Plating at Liquid-Liquid Interfaces Reviewed

    Toshihiko Tsuneyoshi, Yu Yohaze, Takaichi Watanabe, Tsutomu Ono

    LANGMUIR   34 ( 44 )   13183 - 13191   2018.11

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:AMER CHEMICAL SOC  

    We report a simple preparation of free-standing metal films via electroless plating (ELP) at the liquid-liquid (L-L) interface between an aqueous electroless plating solution and an organic solvent. The use of ELP does not require any external energy in the form of heating and stirring. We find that the affinity of the organic solvent for the palladium nanoparticles (PdNPs) as catalysts and the vertical position of the organic and aqueous phases in the biphasic system are important considerations for synthesizing a robust copper film. Specifically, 1,2-dichloroethane which has an appropriate affinity for PdNPs and a higher density than water was found to be a good candidate for use as the organic phase in this system. However, a poor-quality copper film was obtained in the system with 1-hexanol as the organic phase. We also controlled the microscale surface structure of the copper films by using different concentrations of the injected PdNP dispersion. A high density of PdNPs caused smaller regions of metal growth, which contributed to the formation of smoother metal films. Moreover, under the optimal synthesis condition, we confirmed the electrical conductivity of the obtained copper film to be 1.16 X 10(-7) Omega m. We believe that this metal film preparation represents a promising way to produce a range of metal film structures through the use of flexible L-L interfaces as templates.

    DOI: 10.1021/acs.langmuir.8b02822

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  • Polydopamine-Based 3D Colloidal Photonic Materials: Structural Color Balls and Fibers from Melanin-Like Particles with Polydopamine Shell Layers Reviewed

    Michinari Kohri, Kenshi Yanagimoto, Ayaka Kawamura, Kosuke Hamada, Yoshihiko Imai, Takaichi Watanabe, Tsutomu Ono, Tatsuo Taniguchi, Keiki Kishikawa

    ACS APPLIED MATERIALS & INTERFACES   10 ( 9 )   7640 - 7648   2018.3

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:AMER CHEMICAL SOC  

    Nature creates beautiful structural colors, and some of these colors are produced by nanostructural arrays of melanin. Polydopamine (PDA), an artificial black polymer produced by self-oxidative polymerization of dopamine, has attracted extensive attention because of its unique properties. PDA is a melanin-like material, and recent studies have reported that photonic materials based on PDA particles showed structural colors by enhancing color saturation through the absorption of scattered light. Herein, we describe the preparation of three-dimensional (3D) colloidal photonic materials, such as structural color balls and fibers, from biomimetic core shell particles with melanin-like PDA shell layers. Structural color balls were prepared through the combined use of membrane emulsion and heating. We also demonstrated the use of microfluidic emulsification and solvent diffusion for the fabrication of structural color fibers. The obtained 3D colloidal materials, i.e., balls and fibers, exhibited angle-independent structural colors due to the amorphous assembly of PDA-containing particles. These findings provide new insight for the development of dye-free technology for the coloration of various 3D colloidal architectures.

    DOI: 10.1021/acsami.7b03453

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  • Indocyanine green-laden poly(ethylene glycol)-block-polylactide (PEG-b-PLA) nanocapsules incorporating reverse micelles: Effects of PEG-b-PLA composition on the nanocapsule diameter and encapsulation efficiency Reviewed

    Takaichi Watanabe, Yui Sakamoto, Tetsuya Inooka, Yukitaka Kimura, Tsutomu Ono

    COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS   520   764 - 770   2017.5

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER SCIENCE BV  

    Reverse micelles are thermodynamically stable systems, with a capacity to encapsulate hydrophilic molecules in their nanosized core, which is smaller than the core generally obtained with water in -oil-emulsion droplets. Herein, we present a simple technique for the preparation of poly(ethylene glycol)-block-polylactide (PEG-b-PLA) nanocapsules encapsulating a hydrophilic photosensitizer (indocyanine green, ICG), which exploits reverse micelle formation and subsequent emulsion-solvent diffusion. We establish the effect of the PEG-b-PLA composition and the co-surfactant volume on the diameter and water content of the reverse micelles. We demonstrate that the composition of PEG-b-PIA affects also the diameter and encapsulation efficiency of the resulting nanocapsules. We show that the ICG-laden nanocapsulescon fabricated under the most optimal conditions have a diameter of approximately 100 nm and an ICG encapsulation efficiency of 58%. We believe that the method proposed here is a promising step towards the preparation of hydrophilic drug-laden polymer nanocapsules with a small diameter and therefore suitable for use in drug delivery applications based on enhanced permeability and retention (EPR) effect-driven passive targeting. (C) 2017 Elsevier B.V. All rights reserved.

    DOI: 10.1016/j.colsurfa.2017.02.039

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  • MICROFLUIDIC FORMATION OF MONODISPERSE TETRA-PEG HYDROGEL MICROBEADS FOR CELL ENCAPSULATION Reviewed

    Takaichi Watanabe, Shoji Takeuchi

    2016 IEEE 29TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS)   718 - 720   2016

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    This conference proceeding reports a preliminary result regarding a simple technique to fabricate core-shell tetra-arm poly(ethylene glycol) (tetra-PEG) hydrogel microbeads encapsulating insulin-secreting cells using microfluidic emulsification and interfacial coupling reaction of two kinds of tetra-PEG macromonomers at the core-shell interface in the precursor aqueous droplets. Different from conventional PEG-based microbeads formation, in situ gelation system utilizing self-diffusion of the macromonomers in confined microdroplets allowed to prepare tetra-PEG hydrogel microbeads with narrow size distribution under mild gelation condition in the absence of heating and UV irradiation. This technology can be used to generate monodisperse tetra-PEG hydrogel microbeads to encapsulate sensitive cells for regenerative medicines.

    DOI: 10.1109/MEMSYS.2016.7421728

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  • Efficient anti-tumor effect of photodynamic treatment with polymeric nanoparticles composed of polyethylene glycol and polylactic acid block copolymer encapsulating hydrophobic porphyrin derivative Reviewed

    Ken-ichi Ogawara, Taro Shiraishi, Tomoya Araki, Taka-ichi Watanabe, Tsutomu Ono, Kazutaka Higaki

    European Journal of Pharmaceutical Sciences   82   154 - 160   2015.11

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  • Augmented EPR effect by photo-triggered tumor vascular treatment improved therapeutic efficacy of liposomal paclitaxel in mice bearing tumors with low permeable vasculature Reviewed

    Tomoya Araki, Ken-ichi Ogawara, Haruka Suzuki, Rie Kawai, Taka-ichi Watanabe, Tsutomu Ono, Kazutaka Higaki

    JOURNAL OF CONTROLLED RELEASE   200   106 - 114   2015.2

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    The effects of photo-triggered tumor vascular treatment (PVT) on the structural and functional properties of tumor vasculature were assessed in Colon-26 (C26) and B16/BL6 (B16) tumor-bearing mice. Furthermore, anti-tumor efficacy of subsequently injected PEG liposomal paclitaxel (PL-PTX) was also evaluated. As a photosensitizer, a hydrophobic porphyrin derivative was used and formulated in polymeric nanoparticle composed of polyethylene glycol-block-polylactic acid to avoid its non-specific in vivo disposition. In the mice bearing C26 with high permeable vasculature, the prominent anti-tumor activity was confirmed by PVT alone, but the subsequently injected PL-PTX did not show any additive effect. PVT itself initially induced apoptotic cell death of tumor vascular endothelial cells and platelet aggregation, which would have subsequently induced apoptosis of C26 tumor cells surrounding the vasculature. On the other hand, in the mice bearing B16 with low permeable vasculature, PVT enhanced the anti-tumor activity of subsequently injected PL-PTX, which would be attributed to the tumor disposition amount and area of PEG liposomes enhanced by PVT. These results clearly indicated that the treatment would have made it possible to provide more efficient extravasation of PL-PTX, leading to its more potent anti-tumor effect. (C) 2015 Elsevier B.V. All rights reserved.

    DOI: 10.1016/j.jconrel.2014.12.038

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  • Microfluidic-SANS: flow processing of complex fluids Reviewed

    Carlos G. Lopez, Takaichi Watanabe, Anne Martel, Lionel Porcar, Joao T. Cabral

    SCIENTIFIC REPORTS   5   2015.1

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    Understanding and engineering the flow-response of complex and non-Newtonian fluids at a molecular level is a key challenge for their practical utilisation. Here we demonstrate the coupling of microfluidics with small angle neutron scattering (SANS). Microdevices with high neutron transmission (up to 98%), low scattering background (less than or similar to 10(-2) cm(-1)), broad solvent compatibility and high pressure tolerance (approximate to 3-15 bar) are rapidly prototyped via frontal photo polymerisation. Scattering from single microchannels of widths down to 60 mu m, with beam footprint of 500 mu m diameter, was successfully obtained in the scattering vector range 0.01-0.3 angstrom(-1), corresponding to real space dimensions of similar or equal to 10-600 angstrom. We demonstrate our approach by investigating the molecular re-orientation and alignment underpinning the flow response of two model complex fluids, namely cetyl trimethylammonium chloride/pentanol/D2O and sodium lauryl sulfate/octanol/brine lamellar systems. Finally, we assess the applicability and outlook of microfluidic-SANS for high-throughput and flow processing studies, with emphasis of soft matter.

    DOI: 10.1038/srep07727

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  • Insulin secreting cell-laden hydrogel microfiber coated with poly-L-ornithine

    Takaichi Watanabe, Teru Okitsu, Marie Shinohara, Sapana Poudel, Yasuyuki Sakai, Shoji Takeuchi

    MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences   215 - 217   2015

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    This paper describes the preparation of insulin secreting (MIN6m9) cell-laden calcium alginate (Ca-Alg) hydrogel microfiber coated with poly-L-ornithine (PLO) using a microfluidic wet-spinning, followed by layer-by-layer (LbL) deposition to enhance the mechanical strength. Both in vitro and in vivo experiments showed that PLO-coated (PLO-Alg) microfiber had higher mechanical strength than Ca-Alg microfiber. In addition, the cells encapsulated in PLO-Alg microfiber after 7 days of culture secreted insulin in response to glucose concentrations. We believe that PLO-Alg microfiber can be useful for the application in robust tissue graft to achieve long-term implantation.

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  • Monodisperse polylactide microcapsules with a single aqueous core prepared via spontaneous emulsification and solvent diffusion Reviewed

    Takaichi Watanabe, Yukitaka Kimura, Tsutomu Ono

    RSC ADVANCES   4 ( 10 )   4872 - 4877   2014

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    A simple approach to preparing monodisperse poly(D, L-lactide) (PDLLA) microcapsules with a single aqueous core is developed. The method is based on automatic water-in-oil-in-water double emulsion formation from oil-in-water single emulsion via spontaneous emulsification which voluntarily disperses part of continuous aqueous phase into the dispersed oil phase dissolving oil-soluble amphiphilic diblock copolymer, poly(D, L-lactide)-b-poly(2-dimethylaminoethyl methacylate)(PDLLA-b-PDMAEMA), followed by coalescence of tiny water droplets within the polymer droplets, coupled with quick precipitation of polymers by diluting the emulsion with water. In this study, we have investigated the effect of PDLLA to PDLLA-b-PDMAEMA ratios and flow rates of each solution during preparing the emulsion on the final morphology and the size of the microcapsules. It was found that the polymer blend ratio played a crucial role in determining internal structure of the microcapsules. The microcapsules size decreased with the increment of the flow rate ratios of the continuous phase to the dispersed phase and eventually reached 10 mm, while maintaining narrow size distribution. In addition, we have demonstrated that the microcapsules can encapsulate both hydrophilic and hydrophobic compounds during the formation.

    DOI: 10.1039/c3ra44066d

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  • Microchannel wet-spinning of nanofibers

    Tsutomu Ono, Moe Kitanaka, Kazuhisa Kishimoto, Takaichi Watanabe

    Fiber Society Spring 2014 Technical Conference: Fibers for Progress   2014

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    We aim at the establishment of new methodology to produce nanofibers. This facilitates the advanced nanofibers with surface modification and core-shell structure.

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  • Microfluidic Fabrication of Monodisperse Polylactide Microcapsules with Tunable Structures through Rapid Precipitation Reviewed

    Takaichi Watanabe, Yukitaka Kimura, Tsutomu Ono

    LANGMUIR   29 ( 46 )   14082 - 14088   2013.11

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    We describe a versatile and facile route to the continuous production of monodisperse polylactide (PLA) microcapsules with controllable structures. With the combination of microfluidic emulsification, solvent diffusion, and internal phase separation, uniform PLA microcapsules with a perfluorooctyl bromide (PFOB) core were successfully obtained by simply diluting monodisperse ethyl acetate (EA)-in-water emulsion with pure water. Rapid extraction of EA from the droplets into the aqueous phase enabled the solidification of the polymer droplets in a nonequilibrium state during internal phase separation between a concentrated PLA/EA phase and a PFOB phase. Higher-molecular-weight PLA generated structural complexity of the microcapsules, yielding core-shell microcapsules with covered with small PFOB droplets. Removal of the PFOB via freeze drying gave hollow microcapsules with dimpled surfaces. The core-shell ratios and the diameter of these microcapsules could be finely tuned by just adjusting the concentration of PFOB and flow rates on emulsification, respectively. These biocompatible microcapsules with controllable size and structures are potentially applicable in biomedical fields such as drug delivery carriers of many functional molecules.

    DOI: 10.1021/la403883a

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  • Formulation and Evaluation of Paclitaxel-Loaded Polymeric Nanoparticles Composed of Polyethylene Glycol and Polylactic Acid Block Copolymer Reviewed

    Tomoya Araki, Yusuke Kono, Ken-ichi Ogawara, Takaichi Watanabe, Tsutomu Ono, Toshikiro Kimura, Kazutaka Higaki

    BIOLOGICAL & PHARMACEUTICAL BULLETIN   35 ( 8 )   1306 - 1313   2012.8

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    To develop potent paclitaxel (PTX) formulations for cancer chemotherapy, we formulated PTX into polymeric nanoparticles composed of polyethylene glycol (PEG) and polylactic acid (PLA) block copolymer (PN-PTX). First, the physicochemical properties of PN-PTX prepared were assessed; the mean particle size was around 80nm and the zeta potential was found to be almost neutral. Next, the in vitro PTX release property was assessed by a dialysis method. Although rapid release of PTX was observed just after dosing, around 70% of PTX was stably incorporated in polymeric nanoparticles for a long time in the presence of serum. Then, the in vivo pharmacokinetics of PN-PTX after intravenous administration was investigated in Colon-26 (C26) tumor-bearing mice. Both polymeric nanoparticles and PTX incorporated exhibited a long blood circulating property, leading to enhanced permeability and retention (EPR) effect-driven, time-dependent tumor disposition of PTX. Tumor distribution increased gradually for 24h, and tissue uptake clearance of polymeric nanoparticles in the liver and spleen was lower than that of PEG liposomes. Since these results indicated that the in vivo disposition characteristics of PN-PTX were very favorable, we then evaluated the anti-tumor effect of PN-PTX in C26 tumor-bearing mice. However, PN-PTX did not exhibit any significant anti-tumor effect, presumably due to the poor PTX release from polymeric nanoparticles. From these results, it is considered that the favorable pharmacokinetic properties of nanoparticles and the drug incorporated do not always lead to its potent in vivo pharmacological activity, suggesting the importance of PTX release properties within tumor tissues.

    DOI: 10.1248/bpb.b12-0020

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  • Continuous fabrication of monodisperse polylactide microspheres by droplet-to-particle technology using microfluidic emulsification and emulsion-solvent diffusion Reviewed

    Takaichi Watanabe, Tsutomu Ono, Yukitaka Kimura

    SOFT MATTER   7 ( 21 )   9894 - 9897   2011

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    Monodisperse polylactide (PLA) microspheres were continuously fabricated by microfluidic emulsification and subsequent dilution in water. The diameter was precisely tuned from 6 to 50 mu m by changing the flow rate of the fluids in microfluidics or the PLA concentration in the dispersed phase. The use of amphiphilic oil-soluble poly(ethylene glycol)-b-polylactide (o-PEG-PLA) as a matrix resulted in a highly porous microsphere morphology, and the porosity was controlled by blending PLA. Therefore, mono-disperse PLA microspheres with the predetermined surface porosity were continuously produced by just enough reagents and energy.

    DOI: 10.1039/c1sm05910f

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Books

  • 熱制御に向けた相変化材料PCMの開発と応用

    渡邉貴一, 小野努( Role: Joint author ,  バイオベース高分子を殻材とする蓄熱マイクロカプセル)

    シーエムシー出版  2024.4 

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  • 高分子微粒子の最新技術動向

    渡邉貴一, 安原有香, 小野努( Role: Contributor ,  第11章 マイクロ空間における自己多層乳化を利用した単分散多層マイクロカプセルの調製)

    シーエムシー出版  2022.7 

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  • 撹拌技術とスケールアップ、シミュレーションの活用

    渡邉貴一, 小野努( Role: Contributor ,  スラグ流を用いたSoap-free乳化重合による単分散高分子微粒子の連続調製)

    技術情報協会  2021.11 

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  • 高分子イオン液体材料とその分離場への期待 Invited

    渡邉貴一, 小野努

    分離技術   53 ( 5 )   275 - 279   2023.9

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  • Mono-Filament Nanofibers Prepared by Microchannel Wet-Spinning Invited

    Tsutomu Ono, Takaichi Watanabe

    Journal of the Society of Fiber Science and Technology, Japan   79 ( 6 )   188   2023.6

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  • マイクロ空間における水滴内の相分離現象を利用したハイドロゲル微粒子の構造設計 Invited Reviewed

    渡邉貴一

    粉体工学会誌   59 ( 3 )   127 - 130   2022.3

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  • 金属膜で包まれた液体”金属被覆マイクロカプセル”の開発 Invited

    小野努, 渡邉貴一

    C & I Commun   45 ( 3 )   30 - 33   2020.8

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  • マイクロ流路内で形成される単分散な水性二相系液滴を利用したハイドロゲルマイクロカプセルの調製 Invited

    渡邉貴一, 小野努

    混相流   34 ( 6 )   318 - 325   2020.6

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  • マイクロ流体デバイスによる精密コロイド材料調製のための界面設計 Invited

    小野努, 渡邉貴一

    粉体工学会誌   55   340 - 345   2018.6

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  • マイクロ流体デバイスを用いた単分散ポリ乳酸微粒子の連続調製 Invited

    渡邉貴一, 小野努

    ケミカルエンジニヤリング   63 ( 2 )   2018.2

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  • Interface engineering for colloid materials production using a microfluidic process

    Tsutomu Ono, Takaichi Watanabe

    Journal of the Society of Powder Technology, Japan   55 ( 6 )   340 - 345   2018

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    Microfluidics is a fascinating tool for colloidal materials design. It precisely controls the interface of immiscible fluids in a microchannel such as droplets, slug flow and jet flow. Monodisperse droplets prepared by microfluidic emulsification are readily converted into monodisperse particles by solvent diffusion. Furthermore, controlling the inner phase separation leads to construct the capsule structure containing oil or aqueous liquid. Based on the same concept, the rapid solidification from jet flow enables wet-spinning of nanofibers. In this review, we show our experimental procedure and the leading results and discuss key factors to develop such a microfluidic process to produce well-defined materials.

    DOI: 10.4164/sptj.55.340

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  • 再生医療と移植医療の新展開 iPS細胞を用いた次世代型膵島移植療法の開発

    霜田 雅之, 矢部 茂治, 篠原 孝也, 元 文姫, 福田 沙月, 渡邊 亜美, 渡邊 貴一, 篠原 満利恵, 井上 貴史, 伊吹 将人, 酒井 康行, 竹内 昌治, 道上 達男, 大河内 仁志, 佐々木 えりか, 加藤 智久, 宮島 篤

    糖尿病   59 ( Suppl.1 )   S - 106   2016.4

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  • マイクロ流路を用いた微細液滴調製に関する研究動向

    渡邉貴一, 小野努

    化学工学会誌   76 ( 12 )   781 - 782   2012.12

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  • 学生会員の声

    渡邉貴一

    化学工学会誌   78 ( 8 )   530   2011.7

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Presentations

  • マイクロ流体デバイスを利用したソフトマテリアルの精密形成加工 Invited

    渡邉貴一

    第40回物性物理化学研究会  2024.7.12 

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    Event date: 2024.7.12

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

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  • Flow Synthesis of Open-Porous Particles Using Bijel Droplets as the Structural Template

    Takaichi Watanabe, Mina Masaoka, Tsutomu Ono

    The 7th Asian Symposium on Emulsion Polymerization and Functional Polymeric Microspheres (ASEPFPM7)  2024.6.21 

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    Event date: 2024.6.19 - 2024.6.22

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  • Continuous synthesis of open-porous microparticles by pinning of spinodal decomposition in a droplet under flow Invited

    Takaichi Watanabe

    The Third International Process Intensification Conference (IPIC3)  2024.5.30 

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    Event date: 2024.5.28 - 2024.5.31

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  • Structure, solubility and solution rheology of poly(ionic liquids)

    Carlos G. Lopez, Atsushi Matsumoto, Takaichi Watanabe

    APS March Meeting 2024  2024.3.4 

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    Event date: 2024.3.4 - 2024.3.8

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  • Preparation of Polymer Particles with Various Structures Invited

    Takaichi Watanabe

    CES-CHEM 2023 Meeting  2023.12.8 

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    Event date: 2023.12.7 - 2023.12.9

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  • Toughening of Poly(Ionic liquid)-Based Ion Gels by Adding Nanomaterials Invited

    Takaichi Watanabe, Yuna Mizutani, Yume Tao, Carlos G. Lopez, Tsutomu Ono

    2nd International Conference on Polymer Science and Engineering  2023.11.2 

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    Event date: 2023.11.1 - 2023.11.3

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  • Formation of Multi-layer Microcapsule in Microflow Invited

    Takaichi Watanabe

    Flow Chemistry Asia 2023  2023.10.5 

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    Event date: 2023.10.5 - 2023.10.6

    Language:English   Presentation type:Oral presentation (invited, special)  

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  • マイクロフロー空間を活用した非平衡構造を有する高分子微粒子の創出 Invited

    渡邉貴一

    材料化学システム工学討論会2023  2023.9.28 

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    Event date: 2023.9.28 - 2023.9.29

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  • フロープロセスによる高分子微粒子の多層構造制御 Invited

    渡邉貴一

    化学工学会第54回秋季大会  2023.9.13 

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    Event date: 2023.9.11 - 2023.9.13

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  • マイクロ流体工学を駆使したソフトマテリアルの設計と分析 Invited

    渡邉貴一

    化学工学会 粒子流体プロセス部会 熱物質流体工学セミナー2023  2023.9.10 

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    Event date: 2023.9.10

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  • Development of Tough Ion Gels Consisting of Alumina and Poly(ionic liquid)

    11th WORLD CONGRESS OF CHEMICAL ENGINEERING  2023.6.5 

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    Event date: 2023.6.4 - 2023.6.8

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  • Microfluidic Formation of Multilayer Microcapsules by Sequential Liquid–liquid Phase Separation

    Takaichi Watanabe, Yuka Yasuhara, Tsutomu Ono

    2022.7.25 

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    Event date: 2022.7.24 - 2022.7.28

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  • マイクロ空間での非平衡相分離による多層構造イオンゲルマイクロ カプセルの創成 Invited

    渡邉貴一

    2021年度「油化学関連シンポジウム in 岡山」  2021.12.3 

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    Event date: 2021.12.3

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  • SANS studies of polyelectrolytes in organic media

    Anish Gulati, Carlos Gonzalez. Lopez, Ralf Schweins, Olga Matsarskaia, Takaichi Watanabe, Walter Richtering

    2021.9.22 

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    Event date: 2021.9.20 - 2021.9.22

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  • スラグ流を反応場とした単分散高分子微粒子のフロー合成 Invited

    渡邉貴一

    反応工学部会若手会第21回講演会  2022.3.15 

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  • Preparation of Open-Porous Particles via Microfluidics Using Bijel Droplets as the Structural Templates

    Takaichi Watanabe, Mina Masaoka, Tsutomu Ono

    17th International Conference on MicroREaction Technology  2024.10.28 

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    Event date: 2024.10.27 - 2024.10.29

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  • 高分子イオン液体を主骨格とするイオンゲルのアニオン種がゲル物性に与える影響

    渡邉貴一, 水谷友南, Carlos G. Lopez, 小野努

    第73回高分子討論会(新潟大学)  2024.9.26 

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    Event date: 2024.9.26 - 2024.9.28

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • クリック反応性モノマーを用いたイオン液体骨格を有するビトリマーの開発

    常川ひかり, 松本篤, 渡邉貴一, 小野努

    化学工学会第55回秋季大会(北海道大学)  2024.9.13 

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    Event date: 2024.9.11 - 2024.9.13

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  • W/Oスラグ流を用いたシード乳化重合による複合高分子微粒子の調製

    樋本京香, 渡邉貴一, 小野努

    化学工学会第55回秋季大会(北海道大学)  2024.9.13 

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    Event date: 2024.9.11 - 2024.9.13

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  • 環境調和型テレケリックポリマーによる可逆的なエマルション液滴架橋形成

    中山日菜子, 松本篤, 渡邉貴一, 小野努

    化学工学会第55回秋季大会(北海道大学)  2024.9.13 

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    Event date: 2024.9.11 - 2024.9.13

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  • イオンゲルに添加するナノ材料形状が力学特性に与える影響

    渡邉貴一, 水谷友南, Carlos G. Lopez, 小野努

    化学工学会第55回秋季大会(北海道大学)  2024.9.13 

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    Event date: 2024.9.11 - 2024.9.13

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  • Toughening of Poly(ionic liquid) Gels with Nanomaterials Having Different Shapes

    Takaichi Watanabe, Yuna Mizutani, Carlos G. Lopez, Yume Tao, Tsutomu Ono

    The 8th International Soft Matter Conference (ISMC) 2024  2024.8.1 

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    Event date: 2024.7.30 - 2024.8.2

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  • Controlled Viscoelastic Properties of Emulsion with Biocompatible Telechelic Triblock Copolymers

    Hinako Nakayama, Takaichi Watanabe, Tsutomu Ono

    The 7th Asian Symposium on Emulsion Polymerization and Functional Polymeric Microspheres (ASEPFPM7)  2024.6.20 

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    Event date: 2024.6.19 - 2024.6.22

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  • Flow Synthesis of PMMA/PSt Composite Particles Using W/O Slug Flow

    Kyoka Hinomoto, Takaichi Watanabe, Tsutomu Ono

    The 7th Asian Symposium on Emulsion Polymerization and Functional Polymeric Microspheres (ASEPFPM7)  2024.6.20 

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    Event date: 2024.6.19 - 2024.6.22

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  • マイクロ湿式紡糸プロセスを用いたコラーゲン繊維の調製と耐水性付与

    山本燿生, 渡邉貴一, 小野努

    マイクロ湿式紡糸プロセスを用いたコラーゲン繊維の調製と耐水性付与  2024.5.30 

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    Event date: 2024.5.30 - 2024.5.31

    Language:Japanese  

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  • マイクロ湿式紡糸プロセスによる PEDOT:PSS 微細繊維の調製と導電性向上

    中村拳人, 渡邉貴一, 小野努

    日本繊維機械学会第77回年次大会  2024.5.30 

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    Event date: 2024.5.30 - 2024.5.31

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 高分子イオン液体を用いた自己修復イオンゲルの作製と評価

    田尾ゆめ, 渡邉貴一, 小野努

    第35回高分子ゲル研究討論会  2024.1.25 

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    Event date: 2024.1.25 - 2024.1.26

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  • マイクロフロー空間を活用した溶媒拡散による高分子微粒子の形状制御

    森久瑠美, 渡邉貴一, 小野努

    第22回高分子ミクロスフェア討論会  2023.11.21 

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    Event date: 2023.11.20 - 2023.11.22

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • ナノ粒子分散液滴を鋳型とした溶媒拡散による多孔質微粒子のフロー調製

    正岡美奈, 渡邉貴一, 小野努

    第22回高分子ミクロスフェア討論会  2023.11.21 

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    Event date: 2023.11.20 - 2023.11.22

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  • 溶媒誘電率が高分子イオン液体の構造と物性に与える影響

    長田弘斗, 松本篤, 杉原伸治, 前田寧, Hou Can, Carlos G Lopez, 渡邉貴一

    第71回レオロジー討論会  2023.10.19 

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    Event date: 2023.10.19 - 2023.10.20

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  • 架橋高分子イオン液体を主骨格としたイオンゲルのアニオン種が力学特性に与える影響

    水谷友南, 渡邉貴一, 小野努

    化学工学会第54回秋季大会  2023.9.12 

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    Event date: 2023.9.11 - 2023.9.13

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  • Flow Nanoprecipitationにおける溶媒組成が酢酸セルロースナノ粒子調製に与える影響

    本西芳理, 渡邉貴一, 小野努

    化学工学会第54回秋季大会  2023.9.12 

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    Event date: 2023.9.11 - 2023.9.13

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  • マイクロ流体デバイスを用いた溶媒拡散による非球形高分子微粒子の調製

    森久瑠美, 渡邉貴一, 小野努

    化学工学会第54回秋季大会  2023.9.12 

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    Event date: 2023.9.11 - 2023.9.13

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  • 高分子イオン液体を用いた自己修復イオンゲルの作製

    田尾ゆめ, 小野努, 渡邉貴一

    化学工学会第54回秋季大会  2023.9.11 

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    Event date: 2023.9.11 - 2023.9.13

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  • Bijel液滴を鋳型とした多孔質微粒子の調製および構造評価

    正岡美奈, 渡邉貴一, 小野努

    化学工学会第54回秋季大会  2023.9.11 

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    Event date: 2023.9.11 - 2023.9.13

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  • マイクロ湿式紡糸プロセスによるポリアクリロニトリル微細繊維の調製

    中島宙, 渡邉貴一, 小野努

    化学工学会第54回秋季大会  2023.9.11 

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    Event date: 2023.9.11 - 2023.9.13

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  • 多糖類誘導体の合成とその水溶液のレオロジー特性評価

    岩戸怜寧, 渡邉貴一, 小野努

    化学工学会第54回秋季大会  2023.9.11 

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    Event date: 2023.9.11 - 2023.9.13

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  • Affeting Parameters for Fiber Production using Microfluidics

    Tsutomu Ono, Yukari Saijo, Sora Nakajima, Takaichi Watanabe

    The 50th Textile Research Symposium (2023) in Mauritius  2023.9.8 

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    Event date: 2023.9.7 - 2023.9.9

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  • Spontaneous microencapsulation behavior in microchannel flow

    Tsutomu Ono, Yuko Sakai, Takaichi Watanabe

    11th WORLD CONGRESS OF CHEMICAL ENGINEERING  2023.6.8 

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    Event date: 2023.6.4 - 2023.6.8

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  • マイクロ湿式紡糸プロセスを用いた PEDOT:PSS 繊維の調製

    中村拳人, 岸本和久, 渡邉貴一, 小野 努

    日本繊維機械学会 第76回年次大会  2023.6.1 

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    Event date: 2023.6.1 - 2023.6.2

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 乳化液を用いた湿式紡糸による短繊維調製

    小野 努, 西條由佳理, 岸本和久, 渡邉貴一

    日本繊維機械学会 第76回年次大会  2023.6.1 

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    Event date: 2023.6.1 - 2023.6.2

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  • マイクロ湿式紡糸プロセスによるポリアクリロニトリル微細繊維の調製

    中島 宙, 岸本和久, 渡邉貴一, 小野 努

    日本繊維機械学会 第76回年次大会  2023.6.1 

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    Event date: 2023.6.1 - 2023.6.2

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  • Silica/高分子イオン液体から構成されるイオンゲルの粘弾性評価

    渡邉貴一, 水谷友南, 家氏真央, Lopez Carlos G, 小野努

    化学工学会第88年会  2023.3.16 

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    Event date: 2023.3.15 - 2023.3.17

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  • 単層カーボンナノチューブによる高分子イオン液体ゲルの高強度化

    宮脇彩里, 渡邉貴一, 小野努

    第25回化学工学会学生発表会  2023.3.4 

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    Event date: 2023.3.4

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  • CO2分離膜への応用に向けた高分子イオン液体ゲル薄膜の作製

    家氏 真央, 渡邉 貴一, 小野 努, 瀨川 純平, 南方 雅之, 神尾 英治, 松山 秀人

    化学工学会 岡山大会2022  2022.12.19 

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    Event date: 2022.12.19

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  • Tough Double-Network Ion Gels with Single-walled Carbon Nanotubes

    2022.12.3 

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    Event date: 2022.12.3

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  • マイクロフロープロセスを用いたソフトマテリアルの精密成形加工 Invited

    渡邉貴一

    2022年繊維学会秋季研究発表会  2022.11.10 

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    Event date: 2022.11.9 - 2022.11.10

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

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  • Rapid Synthesis of Monodisperse Polymer Particles Using Slug Flow

    Flow Chemistry Asia 2022  2022.10.7 

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    Event date: 2022.10.6 - 2022.10.7

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  • マイクロ流体デバイスを用いたNanoprecipitationによる酢酸セルロース微粒子の調製

    本西芳理, 渡邉貴一, 小野努

    化学工学会第53回秋季大会  2022.9.16 

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    Event date: 2022.9.14 - 2022.9.16

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  • マイクロ湿式紡糸プロセスによる酢酸セルロース蓄熱繊維の調製

    中島宙, 渡邉貴一, 小野努

    化学工学会第53回秋季大会  2022.9.16 

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    Event date: 2022.9.14 - 2022.9.16

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  • マイクロ流路内で起こる自己乳化現象を駆使した多層マイクロカプセルの構造設計

    渡邉貴一, 安原有香, 小野努

    化学工学会第53回秋季大会  2022.9.16 

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    Event date: 2022.9.14 - 2022.9.16

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  • 溶媒拡散によって形成されるBijel液滴を鋳型とした多孔質微粒子の調製

    正岡美奈, 渡邉貴一, 小野努

    化学工学会第53回秋季大会  2022.9.14 

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    Event date: 2022.9.14 - 2022.9.16

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  • マイクロ流体デバイスを利用した単分散バイオポリマーマイクロカプセルの調製と蓄熱材への応用

    坂井優子, 渡邉貴一, 杉森奈緒美, 杉森奈緒美, 池田俊徳, 門前雅之, 小野努

    化学工学会第53回秋季大会  2022.9.14 

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    Event date: 2022.9.14 - 2022.9.16

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  • アルミナを添加した高分子イオン液体ゲルの高強度化

    水谷友南, 渡邉貴一, 小野努

    第71回高分子討論会  2022.9.7 

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    Event date: 2022.9.5 - 2022.9.7

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  • 液滴内での液固相転移現象を利用した鈴型マイクロカプセルの構造制御

    坂井優子, 渡邉貴一, 小野努

    第71回高分子討論会  2022.9.5 

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    Event date: 2022.9.5 - 2022.9.7

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  • 液滴内での自己多層乳化現象を利用した高分子イオン液体カプセルの階層構造制御

    安原有香, 渡邉貴一, 小野努

    第21回高分子ミクロスフェア討論会  2022.3.10 

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    Event date: 2022.3.9 - 2022.3.11

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  • 液滴内での液固相転移現象を利用した鈴型マイクロカプセルの調製と構造制御

    坂井優子, 渡邉貴一, 小野努

    第21回高分子ミクロスフェア討論会  2022.3.10 

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    Event date: 2022.3.9 - 2022.3.11

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  • マイクロ湿式紡糸法を用いた構造色繊維の調製

    渡邉栞菜, 渡邉貴一, 小野努

    化学工学会 第24回化学工学会学生発表会  2022.3.5 

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    Event date: 2022.3.5

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  • マイクロ湿式紡糸デバイスの流路構造がJet流の安定性に及ぼす影響

    末光聖, 真鍋緑, 渡邉貴一, 小野努

    化学工学会 第24回化学工学会学生発表会  2022.3.5 

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  • Tough and hydrophobic ion gels composed of silica nanoparticles/poly(ionic liquid)s for gas separation membranes

    Takaichi Watanabe, Ruri Takahashi, Tsutomu Ono

    2021.12.20 

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    Event date: 2021.12.16 - 2021.12.21

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  • Giant liposomes with controlled structures prepared by dewetting of double emulsions

    Midori Manabe, Takaichi Watanabe, Tsutomu Ono

    The 8th Asian Particle Technology Symposium  2021.10.13 

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    Event date: 2021.10.11 - 2021.10.14

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  • Development of tough and water-repellent cellulose nanofiber/poly(ionic liquid)s double network ion gel

    Takaichi Watanabe, Emiho Oe, Tsutomu Ono

    2021.10.12 

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    Event date: 2021.10.11 - 2021.10.14

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  • マイクロ流体デバイスを利用した鈴型マイクロカプセルの形成機構の解析

    坂井優子, 渡邉貴一, 小野努

    化学工学会 第52回秋季大会  2021.9.23 

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    Event date: 2021.9.22 - 2021.9.24

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  • W/O/Wエマルションを鋳型としたマイクロカプセルの膜構造制御

    真鍋緑, 渡邉貴一, 小野努

    化学工学会 第52回秋季大会  2021.9.22 

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    Event date: 2021.9.22 - 2021.9.24

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  • マイクロ流路を用いた単分散ハイドロゲル微粒子の生成とその構造制御 Invited

    渡邉貴一

    粉体工学会2021年度 春期研究発表会  2021.6.3 

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    Event date: 2021.6.2 - 2021.6.3

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  • マイクロ湿式紡糸法によるポリアミック酸ナノ繊維の調製

    岡田慧, 渡邉貴一, 小野努

    マイクロ湿式紡糸法によるポリアミック酸ナノ繊維の調製  2021.5.28 

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    Event date: 2021.5.27 - 2021.5.28

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  • マイクロ湿式紡糸法を用いたポリ乳酸繊維調製における送液条件が結晶性に与える影響

    渡邉貴一, 松本彬, 小野努

    日本繊維機械学会第74回年次大会  2021.5.28 

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    Event date: 2021.5.27 - 2021.5.28

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  • マイクロ湿式紡糸法によるコラーゲン繊維の調製

    高野創也, 渡邉貴一, 小野努

    日本繊維機械学会第74回年次大会  2021.5.27 

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    Event date: 2021.5.27 - 2021.5.28

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  • Designing Complex Particle Structures by Phase Separation in Droplets Invited

    Takaichi Watanabe

    International Chemical Engineering Symposia 2021  2021.3.22 

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    Event date: 2021.3.20 - 2021.3.21

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  • CNF水分散液を原料としたマイクロ湿式紡糸プロセスによるセルロース繊維の調製

    道行大将, 渡邉貴一, 小野努

    第23回化学工学会学生発表会  2021.3.6 

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    Event date: 2021.3.6

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  • マイクロ湿式紡糸プロセスによるポリアミック酸繊維の調製と機能性評価

    岡田慧, 渡邉貴一, 小野努

    第23回化学工学会学生発表会  2021.3.6 

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  • マイクロ湿式紡糸によるステレオコンプレックスポリ乳酸ファイバーの調製

    松本彬, 渡邉貴一, 小野努

    第23回化学工学会学生発表会  2021.3.6 

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    Event date: 2021.3.6

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  • ホルムアルデヒドを使わないメラミンマイクロカプセルの開発

    笠嶋拳人, 渡邉貴一, 小野努

    第23回化学工学会学生発表会  2021.3.6 

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    Event date: 2021.3.6

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  • セルロースナノファイバーの添加による高分子イオン液体ゲルの高強度化

    大江笑北, 渡邉貴一, 小野努

    第23回化学工学会学生発表会  2021.3.6 

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    Event date: 2021.3.6

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  • 液滴内での迅速な溶媒拡散誘起相分離を用いた共連続構造を有する高分子微粒子の調製

    武内裕城, 渡邉貴一, 小野努

    化学工学会 広島大会2020  2020.12.11 

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    Event date: 2020.12.11

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • マイクロ湿式紡糸プロセスによるコラーゲン繊維の調製

    高野創也, 渡邉貴一, 小野努

    化学工学会 広島大会2020  2020.12.11 

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    Event date: 2020.12.11

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  • 高分子イオン液体を用いた高強度イオンゲルの開発 Invited

    渡邉貴一

    日本化学会中国四国支部  2020.11.29 

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    Event date: 2020.11.28 - 2020.11.29

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

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  • クリック反応を利用した主鎖型高分子イオン液体および架橋体の開発

    平井瑠夏, 渡邉貴一, 小野努

    第29回ポリマー材料フォーラム  2020.11.27 

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    Event date: 2020.11.26 - 2020.11.27

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  • 異なるカーボンナノチューブ(CNT)原料を用いたマイクロ湿式紡糸プロセスによるCNT繊維の調製

    入江智紀, 渡邉貴一, 小野努

    日本繊維機械学会研究発表会  2020.11.10 

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    Event date: 2020.11.10

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  • 高分子イオン液体イオンゲルの高強度化に関する設計指針の構築 (再発表)

    渡邉貴一, 髙橋るり, 小野努

    化学工学会 第51回秋季大会  2020.9.25 

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    Event date: 2020.9.24 - 2020.9.26

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  • 重合誘起相分離による微粒子内部の微細構造制御

    安原有香, 渡邉貴一, 小野努, Itab Yousself, Serra Christophe

    化学工学会 第51回秋季大会  2020.9.24 

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    Event date: 2020.9.24 - 2020.9.26

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  • 光重合による樹脂表面への高分子イオン液体層の構築(再発表)

    荒木拓也, 渡邉貴一, 小野努

    化学工学会 第51回秋季大会  2020.9.24 

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    Event date: 2020.9.24 - 2020.9.26

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  • クリック反応性モノマーを利用した主鎖型高分子イオン液体の作製および物性評価

    平井瑠夏, 渡邉貴一, 小野努

    第69回高分子討論会  2020.9.18 

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    Event date: 2020.9.16 - 2020.9.18

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  • 液体塞栓物質としてのアルギン酸溶液と造影剤混合液の検証:動脈瘤モデルおよび豚腎動脈における塞栓実験

    宇賀真由, 渡邉貴一, 石田裕朗, 髙橋るり, 小牧稔幸, 梶田聡一郎, 冨田晃司, 松井裕輔, 櫻井淳, 生口俊浩, 平木隆夫, 郷原英夫, 小野努, 金澤右

    第49回日本IVR学会総会  2020.8.25 

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    Event date: 2020.8.25 - 2020.8.27

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  • マイクロ流路を利用したナノファイバーの湿式紡糸と配向性の向上

    小野努, 渡邉貴一

    2020年繊維学会年次大会  2020.6.12 

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    Event date: 2020.6.10 - 2020.6.12

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  • カーボンナノチューブ分散液を原料としたモノフィラメント繊維の調製

    入江智紀, 渡邉貴一, 小野努

    日本繊維機械学会第73回年次大会  2020.6.5 

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    Event date: 2020.6.4 - 2020.6.5

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  • クリック反応を利用した主鎖型高分子イオン液体の合成および評価

    平井瑠夏, 渡邉貴一, 小野努

    第69回高分子年次大会  2020.5.27 

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    Event date: 2020.5.27 - 2020.5.28

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  • 高分子イオン液体イオンゲルの高強度化に関する設計指針の構築

    渡邉貴一,高橋るり,小野努

    化学工学会 第85年会  2020.3.17 

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    Event date: 2020.3.15 - 2020.3.17

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  • カーボンナノチューブ 分散液を原料としたモノフィラメント繊維の連続調製

    入江智紀,渡邉貴一,小野努

    化学工学会 第85年会  2020.3.16 

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    Event date: 2020.3.15 - 2020.3.17

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  • 光重合による樹脂表面への高分子イオン液体層の構築

    荒木拓也,渡邉貴一,小野努

    化学工学会 第85年会  2020.3.16 

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    Event date: 2020.3.15 - 2020.3.17

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  • ファウリングを引き起こす重合反応モデルの構築 Invited

    小野努,苅田健吾,川口佳,渡邉貴一

    化学工学会 第85年会  2020.3.15 

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    Event date: 2020.3.15 - 2020.3.17

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  • マイクロ湿式紡糸プロセスによるセルロースナノファイバーの長繊維化

    宮林敬典,渡邉貴一,小野努

    第22回化学工学会学生発表会(岡山大会)  2020.3.7 

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    Event date: 2020.3.7

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  • マイクロフロー空間における逐次的な相分離現象を利用した多層マイクロカプセルの創製 Invited

    渡邉貴一

    第14回機能性微粒子分科会セミナー  2022.1.14 

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  • 電気をよく通す高分子イオン液体材料の開発

    渡邉貴一

    新技術説明会  2021.12.23 

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  • 連続晶析プロセスにおけるスラグ流が晶析挙動に与える影響

    神吉翔太, 渡邉貴一, 小野努

    化学工学会姫路大会2019  2019.12.17 

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  • 不均一系RAFT重合による高分子微粒子の合成

    川口佳, 渡邉貴一, 小野努

    化学工学会姫路大会2019  2019.12.17 

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  • クリック反応性モノマーを用いた架橋高分子イオン液体の合成および評価

    平井瑠夏, 渡邉貴一, 小野努

    第10回イオン液体討論会  2019.11.21 

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  • 高分子イオン液体を用いたイオンゲルの作製とダブルネットワーク構造による高強度化

    高橋るり, 渡邉貴一, 小野努

    第10回イオン液体討論会  2019.11.21 

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  • Preparation of metal-shell microcapsules using Pickering emulsion and interfacial electroless plating International conference

    Toshihiko Tsuneyoshi, Takaichi Watanabe, Tsutomu Ono

    Okinawa Colloids 2019  2019.11.8 

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  • Synthesis of poly (methyl methacrylate)/polystyrene composite particles by soap-free seeded emulsion polymerization using a water-in-oil slug flow in a microchannel International conference

    Kengo Karita, Takaichi Watanabe, Tsutomu Ono

    Okinawa Colloids 2019  2019.11.6 

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  • Preparation of double network ion gels with silica particles and poly (ionic liquid)s International conference

    Ruri Takahashi, Takaichi Watanabe, Tsutomu Ono

    Okinawa Colloids 2019  2019.11.6 

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  • Microfluidic preparation of Janus hydrogel microparticles using aqueous two-phase system droplets as a template International conference

    Takaichi Watanabe, Kae Ikegami, Ibuki Motohiro, Tsutomu Ono

    Okinawa Colloids 2019  2019.11.4 

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  • Structural Control of Hydrogel Microparticles by Combining Phase Separation and Cross-linking Reaction in Aqueous Droplets International conference

    Takaichi Watanabe, Ibuki Motohiro, Kae Ikegami, Tsutomu Ono

    APPChE 2019  2019.9.26 

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  • Nucleation behaviors in nano- and pico-liter droplets using microfluidic crystallization International conference

    Tsutomu Ono, Yayoi Kawashima, Takaichi Watanabe

    APPChE 2019  2019.9.25 

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  • Preparation of Formaldehyde-free Melamine Microcapsules International conference

    Yunlong Cui, Takaichi Watanabe, Tsutomu Ono

    APPChE 2019  2019.9.24 

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  • Microfluidics for nanofiber wet-spinning International conference

    Tsutomu Ono, Takaichi Watanabe

    TechConnect World 2019  2019.6.18 

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  • Preparation of hollow polymer fibers with controlled internal structures using microchannel wet-spinning process and phase separation International conference

    Takaichi Watanabe, Shohei Toyota, Tsutomu Ono

    47th Textile Research Symposium 2019  2019.6.17 

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  • マイクロ湿式紡糸プロセスによる構造タンパク質ナノ繊維の調製

    清家尚也, 今井慶彦, 渡邉貴一, 小野努, 佐藤健大, 村田真也, 森永隆志

    日本繊維機械学会第72回年次大会  2019.5.31 

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  • マイクロ流路内における溶媒拡散法を用いた酢酸セルロースナノ繊維の調製

    恩地哲生, 渡邉貴一, 小野努, 小林慧子, 大村雅也

    日本繊維機械学会第72回年次大会  2019.5.31 

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  • 液滴界面を鋳型とした無電解めっきによる金属マイクロカプセルの調製

    恒吉俊彦, 渡邉貴一, 小野努

    化学工学会第84年会  2019.3.15 

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  • 液滴内での相分離を利用した微粒子の構造制御

    渡邉貴一

    化学工学会第84年会  2019.3.15 

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  • 液滴界面におけるシリカナノ粒子間でのポリ乳酸ステレオコンプレックス形成を利用したマイクロカプセル調製

    藤野麻衣, 渡邉貴一, 小野努

    化学工学会第84年会  2019.3.14 

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  • マイクロ湿式紡糸プロセスにおけるデバイス内部の流体解析

    西岡莉那, 渡邉貴一, 小野努

    第21回化学工学会学生発表会(京都大会)  2019.3.2 

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  • イオン液体シランカップリング剤を用いた表面処理とその表面特性

    青野竜征, 渡邉貴一, 小野努

    第21回化学工学会学生発表会(京都大会)  2019.3.2 

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  • 水性二相液滴を鋳型としたヤヌス型ゲル微粒子の調製

    池上華絵, 元廣 伊吹, 渡邉 貴一, 小野 努

    第21回化学工学会学生発表会(京都大会)  2019.3.2 

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  • 湿式紡糸による多層ジェット流を利用した複合繊維の調製

    川上晃聖, 渡邉貴一, 小野努

    第21回化学工学会学生発表会(京都大会)  2019.3.2 

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  • フロープロセスを用いた簡便な機能性マイクロカプセル調製技術

    渡邉貴一

    第9回化粧品開発展アカデミックフォーラム  2019.2.1 

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  • 量子ドットのフロー合成に及ぼすマイクロ流路の検討

    竹原拓矢, 渡邉貴一, 小野努

    化学工学会中四国関西支部合同徳島大会  2018.12.8 

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  • 酸化鉄含有高分子フィルムの調製と光熱変換によるフィルム特性の変化

    荻田咲耶子, 渡邉貴一, 小野努

    化学工学会中四国関西支部合同徳島大会  2018.12.8 

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  • Mitigation of void formation in polymer fibers prepared by microchannel wet-spinning process International conference

    Naoya Seike, Takaichi Watanabe, Tsutomu Ono

    13th Korea-Japan Symposium on Materials and Interfaces  2018.11.22 

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  • Metal Microcapsules Prepared by Electroless-plating on Pickering Emulsion International conference

    Toshihiko Tsuneyoshi, Takaichi Watanabe, Tsutomu Ono

    13th Korea-Japan Symposium on Materials and Interfaces  2018.11.22 

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  • Modification of poly ionic liquids layer on solid surfaces and wettability control by cation and anion species International conference

    Shoki Tanaka, Takaichi Watanabe, Tsutomu Ono

    13th Korea-Japan Symposium on Materials and Interfaces  2018.11.22 

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  • Preparation of cellulose fibers using ionic liquid by microchannel wet-spinning process International conference

    Tetsuo Onji, Takaichi Watanabe, Tsutomu Ono

    13th Korea-Japan Symposium on Materials and Interfaces  2018.11.21 

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  • 単分散水滴内での相分離を活用したハイドロゲル微粒子の合成と構造制御

    渡邉貴一, 元廣伊吹, 小野努

    第20回高分子ミクロスフェア討論会  2018.11.16 

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  • Water-in-Oilスラグ流を反応場としたソープフリー乳化重合による高分子量ポリマーの合成

    苅田健吾, 渡邉貴一, 小野努

    第20回高分子ミクロスフェア討論会  2018.11.14 

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  • 固体表面への高分子イオン液体層の構築とカチオンおよびアニオン種による濡れ性制御

    田中将貴, 渡邉貴一, 小野努

    第9回イオン液体討論会  2018.10.30 

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  • イオン液体部位をネットワーク骨格に導入したイオノゲル調製

    髙橋るり, 渡邉貴一, 小野努

    第9回イオン液体討論会  2018.10.30 

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  • Synthesis of size and light emission controlled quantum dots using microreactor International conference

    Takuya Takehara, Takaichi Watanabe, Tsutomu Ono

    15th International Conference on MicroREaction Technology  2018.10.22 

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  • Preparation of poly(vinyl alcohol) fiber by microchannel wet-spinning process International conference

    Shinya Masumoto, Takaichi Watanabe, Tsutomu Ono

    15th International Conference on MicroREaction Technology th International Conference on MicroREaction Technology  2018.10.22 

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  • Soap-free emulsion polymerization in water-in-oil slug flow for synthesis of high-molecular weight polystyrene particles International conference

    Kengo Karita, Takaichi Watanabe, Tsutomu Ono

    15th International Conference on MicroREaction Technology  2018.10.22 

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  • 溶媒拡散を用いた両連続相構造を持つ複合液滴 (Bijelカプセル) の調製

    石田裕朗, 渡邉貴一, 小野努

    化学工学会第50回秋季大会  2018.9.20 

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  • シロキサンネットワーク/高分子イオン液体複合イオノゲルの作製

    髙橋るり, 渡邉貴一, 小野努

    化学工学会第50回秋季大会  2018.9.20 

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  • マイクロ湿式紡糸プロセスにおける繊維物性に与える操作因子

    小野努, 渡邉貴一

    日本繊維機械学会第71回年次大会  2018.6.2 

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  • 無機材料表面への高分子イオン液体の修飾およびその評価

    田中将貴, 渡邉貴一, 小野努

    化学工学会第83年会  2018.3.14 

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  • マイクロ空間内での量子ドットの連続合成

    竹原拓矢, 渡邉貴一, 小野努

    化学工学会第83年会  2018.3.14 

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  • Structural Control of Hydrogel Microparticles Using Aqueous Two Phase Separation within Emulsion Droplets International conference

    Takaichi Watanabe, Ibuki Motohiro, Tsutomu Ono

    The 6th Asian Symposium on Emulsion Polymerization and Functional Polymeric Microspheres  2018.3.8 

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  • Stereocomplexed polylactide-based nanocapsules for controlling the release behavior of encapsulated molecules International conference

    Sayako Ogita, Yui Sakamoto, Takaichi Watanabe, Tsutomu Ono

    The 6th Asian Symposium on Emulsion Polymerization and Functional Polymeric Microspheres  2018.3.8 

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  • 単分散微粒子の合成とそのレオロジー特性におよぼす諸因子の検討

    森崎舞, 渡邉貴一, 小野努

    第20回化学工学会学生発表会(東広島大会)  2018.3.3 

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  • ピッカリングエマルションを鋳型としたマイクロカプセルの調製

    松浦絵梨, 渡邉貴一, 小野努

    第20回化学工学会学生発表会(東広島大会)  2018.3.3 

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  • Nucleation behavior of lysozyme in monodisperse droplet-based crystallization International conference

    Yayoi Kawashima, Takaichi Watanabe, Tsutomu Ono

    5 th European Conference on Microfluidics  2018.2.28 

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Industrial property rights

  • 短繊維の製造方法、及び当該方法により製造された短繊維

    小野努, 渡邉貴一

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    Application no:特願2022-085583  Date applied:2022.5.25

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  • 塞栓物質の作製⽅法、塞栓物質および塞栓物質作製⽤キット

    宇賀麻由, 渡邉貴一

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    Application no:特願2020-068949  Date applied:2020.4.7

    Patent/Registration no:特許第7430904号  Date registered:2024.2.5 

    Rights holder:宇賀真由, 渡邉貴一

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  • 湿式紡糸繊維、湿式成膜フィルムおよびそれらの製造方法

    小野努,渡邉貴一

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    Application no:特願PCT/JP/2019/038576  Date applied:2019.9.30

    Announcement no:特開WO2020-067570  Date announced:2021.9.16

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  • ボイドが形成された細径繊維

    小野努, 渡邉貴一, 佐藤健大

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    Application no:特願2019-180933  Date applied:2019.9.30

    Announcement no:特開2021-055222  Date announced:2021.4.8

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  • イオン液体モノマー、高分子およびその製造方法並びに架橋高分子

    小野努, 渡邉貴一

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    Application no:特願2019-164247  Date applied:2019.9.10

    Announcement no:特開2021-042150  Date announced:2021.3.18

    Patent/Registration no:特許第7376072号  Date registered:2023.10.30 

    Rights holder:小野努, 渡邉貴一

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  • タンパク質繊維の製造方法

    小野努, 渡邉貴一, 佐藤健大

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    Application no:特願2019-014565  Date applied:2019.1.30

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  • 体内移植用のハイドロゲルファイバ及びハイドロゲルファイバを用いた体内移植方法

    竹内昌治, 興津輝, 渡邉貴一, 小沢文智, 長田翔伍

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    Application no:特願2016-221135  Date applied:2016.11.14

    Announcement no:特開2018-078917  Date announced:2018.5.24

    Patent/Registration no:特許第6935896号  Date registered:2021.8.30 

    Rights holder:竹内昌治;興津輝;渡邉貴一;小沢文智;長田翔伍

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Awards

  • 第3回「八雲賞」

    2021.11   公益財団法人 八雲環境科学振興財団  

    渡邉貴一

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  • 日本繊維機械学会第70回年次大会学術奨励賞

    2017.6   日本繊維機械学会  

    渡邉貴一

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  • Frontiers of Polymer Colloids, Best Poster Awards

    2014.7  

    渡邉貴一

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  • 13th International Conference on MicroREaction Technology(IMRET13) Best Poster Awards

    2014.6  

    渡邉貴一

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  • 化学工学会第79回年会 学生賞(特別賞)

    2014.3  

    渡邉貴一

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  • 岡山大学大学院自然科学研究科長賞

    2014.3  

    渡邉貴一

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  • Erasmus Mundus Build On Euro-Asian Mobility奨学生

    2012.4  

    渡邉貴一

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  • 平成24年度岡山大学大学院環境学研究科学生奨励研究費

    2011.4  

    渡邉貴一

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  • 第4回中四国若手CE合宿優秀ポスター発表賞

    2010.9  

    渡邉 貴一

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  • 平成21年度岡山大学大学院環境学研究科特待生

    2009.4  

    渡邉貴一

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  • 平成20年度化学工学会中四国支部長賞

    2009.3  

    渡邉貴一

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Research Projects

  • Precise design of colloidal materials in microchannel using non-equilibrium fluid as a template

    2024.04 - 2028.03

    日本学術振興会  科学研究費助成事業 基盤研究B 

    Takaichi Watanabe

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    Authorship:Principal investigator 

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  • Development of poly(ionic liquid) gels for wearable strain sensor with excellent water resistance

    2024.04 - 2025.03

    公益財団法人 JKA  2024年度 研究助成事業 

    Takaichi Watanabe

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    Authorship:Principal investigator 

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  • クリック反応性イオン液体モノマーを基盤とした新規主鎖型高分子イオン液体材料の開発とその応用展開

    2023.06 - 2025.05

    徳山科学技術振興財団  2023年度発展研究助成 

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\5000000 ( Direct expense: \5000000 )

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  • 超高分子量高分子イオン液体を主骨格とする耐久性に優れた帯電防止剤の開発

    2023.06 - 2024.02

    岡山県  令和5年度特別電源所在県科学技術振興事業 

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1300000 ( Direct expense: \1181819 、 Indirect expense:\118181 )

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  • 高分子イオン液体を主骨格とするデザイナブルかつ耐久性に優れた帯電防止剤の開発

    2022.06 - 2023.02

    岡山県  令和4年度特別電源所在県科学技術振興事業 

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1200000 ( Direct expense: \1090000 、 Indirect expense:\110000 )

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  • スラグ流を反応場としたコアシェル型微粒子の高速合成

    2022.04 - 2023.03

    公益財団法人 ホソカワ粉体工学振興財団  令和3年度研究助成 

    渡邉貴一

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\800000 ( Direct expense: \800000 )

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  • 過酷環境で使用できるタフネスと自己修復性を両立した高分子イオン液体ゲル材料の開発

    Grant number:21W2M076  2022.03 - 2023.03

    国立研究開発法人 新エネルギー・産業技術総合開発機構  官民による若手研究者発掘支援事業(若サポ)マッチングサポートフェーズ 

    渡邉貴一

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\10000000 ( Direct expense: \7692000 、 Indirect expense:\2308000 )

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  • クリック反応性イオン液体モノマーを基盤とする主鎖型高分子イオン液体材料の創製と物性制御

    2021.06 - 2022.05

    徳山科学技術振興財団  2021年度研究助成 

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\2000000 ( Direct expense: \2000000 )

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  • 撥水・撥油性と帯電防止性を材料表面に付加する高分子イオン液体コーティング剤の開発

    2021.06 - 2022.02

    岡山県  令和3年度特別電源所在県科学技術振興事業 

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1400000 ( Direct expense: \1273000 、 Indirect expense:\127000 )

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  • マイクロ流路内の小角中性子散乱解析を利用した高分子イオン液体材料の非平衡構造制御

    Grant number:20KK0325  2021.04 - 2024.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))

    Takaichi Watanabe

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\14170000 ( Direct expense: \10900000 、 Indirect expense:\3270000 )

    ナノ粒子と高分子イオン液体をネットワークとする高強度イオンゲルは、高性能な二酸化炭素分離膜や過酷条件で作動するアクチュエーターなどへの応用が期待される。本研究では、海外共同研究者の開発した流動場における中性子線散乱手法やレオロジー測定技術を駆使してイオンゲル内のミクロなネットワーク構造を明らかにし、高強度化に寄与する因子を解明することを目的としている。初年度はコロナ禍のため、海外共同研究者の所属機関を訪問することはできなかったが、申請者が作製したゲルサンプル、高分子を相手先に送付し、それら溶液物性に関する基本的な実験条件の設定を現地で進めた。具体的には、イオンゲルの架橋ネットワークを形成する高分子イオン液体の溶液中でのレオロジー測定、静的光散乱、小角中性子線散乱などのデータを取得し、高分子イオン液体の分子量を推定した。また、膨潤溶媒によって高分子イオン液体の高分子電解質としての振る舞いが大きく変化することが示唆された。この原因はまだわかっていないが、この特性はゲル調製時の力学特性に影響しうるファクターだと考えている。また、ナノ粒子の組成によって、イオンゲルの強度が大きく変化することを見いだした。海外共同研究者と蜜に連携するため、毎週、オンライン会議システムまたはEmailでのやり取りによって、データ解析に関する議論を実施した。また次年度に向けて、渡航の手続きを進めた。さらに、各国の放射光施設への共同利用申請書を申請した。

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  • マイクロ空間の非平衡液滴内で起こる迅速な相転移を駆使した高分子材料の階層構造制御

    2021.04 - 2024.03

    日本学術振興会 科学研究費助成事業  基盤研究C 

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4160000 ( Direct expense: \3200000 、 Indirect expense:\960000 )

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  • 令和2年度プレ国際共同研究支援プログラム

    2020.11 - 2021.03

    国立大学法人岡山大学 

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    Authorship:Principal investigator 

    Grant amount:\300000 ( Direct expense: \300000 )

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  • マイクロフロー法と自動化画像解析によるダブルエマルション製造法の革新

    2020.08 - 2021.02

    総合物質創製化学研究推進機構  令和2年度 融合創発研究 

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  • 温室効果ガスの大幅削減を指向した環境低負荷な蓄熱マイクロカプセルの開発

    2020.06 - 2021.03

    公益財団法人 八雲環境科学振興財団  令和2年度 環境研究助成事業 

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    Authorship:Principal investigator 

    Grant amount:\1000000 ( Direct expense: \1000000 )

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  • 一段階の高分子イオン液体コーティングによる材料表面への撥水・撥油性の同時呈示

    2020.06 - 2021.02

    岡山県  令和2年度特別電源所在県科学技術振興事業 

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    Authorship:Principal investigator 

    Grant amount:\1300000

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  • 液滴内での迅速な相転移を利用したモノリス膜構造を有するマイクロカプセルの開発

    2020.04 - 2021.03

    公益財団法人 池谷科学技術振興財団  2020年度研究助成 単年度研究助成 

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    Authorship:Principal investigator 

    Grant amount:\1500000 ( Direct expense: \1500000 )

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  • フロープロセスによる単分散酢酸セルロースマイクロカプセルの高速生産

    2019.09 - 2020.08

    国立研究開発法人科学技術振興機構  2019年度A-STEP機能検証フェーズ試験研究タイプ 

    渡邉貴一

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\2990000

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  • 高分子ナノ繊維の高速大量生産を実現するマイクロ流体デバイスの開発

    2019.09 - 2020.03

    国立大学法人岡山大学  令和元年度研究推進機構「プレ共同研究」支援事業 

    渡邉貴一

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\300000

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  • 撥水・撥油表面を同時に実現する高分子イオン液体コーティング剤の開発

    2019.06 - 2020.02

    岡山県  令和元年度特別電源所在県科学技術振興事業 

    渡邉貴一

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1100000

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  • マイクロ空間を利用した高分子イオン液体コロイド材料の創製と機能創発

    2019.04 - 2021.03

    日本学術振興会 科学研究費助成事業  若手研究 

    渡邉貴一

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4290000 ( Direct expense: \3300000 、 Indirect expense:\990000 )

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  • マイクロ空間での迅速な相転移を利用した単分散モノリス微粒子の連続調製とその構造制御

    2019.04 - 2020.03

    京都科学技術センター 2019年度研究助成 

    渡邉貴一

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1000000 ( Direct expense: \1000000 )

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  • 水/水エマルションの安定化を指向する界面設計技術の構築とカプセル材料開発への応用

    2018.11 - 2019.03

    国立大学法人岡山大学  平成30年度若手教員研究費支援事業 

    渡邉貴一

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\300000

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  • マイクロ空間での迅速界面反応を利用したカプセル型移植材料の開発

    2016.06 - 2017.03

    公益財団法人 岡山工学振興会  奨励研究助成 

    渡邉貴一

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\375000

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  • マイクロ空間での界面カップリング反応を利用した免疫隔離ハイドロゲルカプセルの開発

    2016.04 - 2018.03

    日本学術振興会 科学研究費助成事業  若手研究B 

    渡邉貴一

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3900000 ( Direct expense: \3000000 、 Indirect expense:\900000 )

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  • Development of controlled interface design for metal assembly on soft interface

    Grant number:16K14459  2016.04 - 2018.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Challenging Exploratory Research

    Ono Tsutomu, Watanabe Takaichi, TSUNEYOSHI Toshihiko, Imai Yoshihiko, Yohaze Yu

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    Grant amount:\3640000 ( Direct expense: \2800000 、 Indirect expense:\840000 )

    Surface functionalization is a promising technology to create worthy materials. So far, however, there was little effort to accumulate metal element at the interface. We have challenged to obtain the interfacial metal assembly using metallo-supermolecular surfactant. Besides such metal assembly, we have developed metal thin film formation at the liquid-liquid interface by interface assembly of palladium nanoparticles and electroless plating on the soft interface.

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  • 糖尿病治療のためのカートリッジ式膵島移植片の開発

    2015.11 - 2018.03

    公益財団法人テルモ生命科学振興財団  2015年度 特定研究開発助成 

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    Authorship:Coinvestigator(s) 

    Grant amount:\30000000

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  • Controlling nucleation behavior and the subsequent phase transition in segmented flow

    Grant number:26289291  2014.04 - 2017.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

    Ono Tsutomu, WATANABE Takaichi

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    Grant amount:\16120000 ( Direct expense: \12400000 、 Indirect expense:\3720000 )

    Nucleation behavior in segmented flow such as droplets and slug flow was investigated from the viewpoints of crystallization and soap-free emulsion polymerization. Nucleation analysis using microfluidic crystallization realized the measurement of nucleation rate. In soap-free emulsion polymerization using microchannels, we found the new polymerization behavior containing fast mass transfer and controlled nucleation. These findings are promising to improve the efficient production tool and the materials design.

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  • マイクロ空間でのTip-streamingを利用したポリ乳酸複合ナノ材料の開発

    2013.04 - 2014.12

    日本学術振興会 特別研究員奨励費 

    渡邉貴一

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\2760000 ( Direct expense: \2400000 、 Indirect expense:\360000 )

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Class subject in charge

  • Chemical Engineering 4 (2024academic year) Fourth semester  - 金1~2

  • Chemical Reaction Engineering Ⅱ (2024academic year) Fourth semester  - 金1~2

  • Synthetic Chemistry Experiment 3 (2024academic year) Third semester  - 火5~8,金5~8

  • Introduction to Practical Informatics and Computational Chemistry (2024academic year) Late  - 木3~4

  • Seminar on Applied Chemistry 1 (2024academic year) Prophase  - その他

  • Seminar on Applied Chemistry 2 (2024academic year) Late  - その他

  • Applied Chemistry Experiment 2 (2024academic year) Third semester  - 火5~8,金5~8

  • Research Works for Master Thesis on Applied Chemistry (2024academic year) Year-round  - その他

  • Seminar in Advanced Chemistry (2024academic year) Other  - その他

  • Design of Organic Materials (2024academic year) Late  - 月1~2

  • Material Process Experiment 3 (2024academic year) Third semester  - 火5~8,金5~8

  • Functional Polymer Chemistry 1 (2024academic year) Late  - その他

  • Functional Polymer Chemistry 2 (2024academic year) Late  - その他

  • Advanced Study (2024academic year) Other  - その他

  • Biotechnology experiment 2 (2024academic year) 1st semester  - 月5~8,木5~8

  • Seminar in Interface Process Engineering (2024academic year) Year-round  - その他

  • Process Integration into Society (2024academic year) Prophase  - その他

  • Chemical Engineering 4 (2023academic year) Fourth semester  - 金1~2

  • Chemical Reaction Engineering Ⅱ (2023academic year) Fourth semester  - 金1~2

  • Synthetic Chemistry Experiment 3 (2023academic year) Third semester  - 火5~8,金5~8

  • Introduction to Practical Informatics and Computational Chemistry (2023academic year) Late  - 木3~4

  • Seminar on Applied Chemistry 1 (2023academic year) Prophase  - その他

  • Seminar on Applied Chemistry 2 (2023academic year) Late  - その他

  • Applied Chemistry Experiment 2 (2023academic year) Third semester  - 火5~8,金5~8

  • Research Works for Master Thesis on Applied Chemistry (2023academic year) Year-round  - その他

  • Seminar in Advanced Chemistry (2023academic year) Other  - その他

  • Design of Organic Materials (2023academic year) Late  - 月1~2

  • Material Process Experiment 3 (2023academic year) Third semester  - 火5~8,金5~8

  • Functional Polymer Chemistry 1 (2023academic year) Late  - その他

  • Functional Polymer Chemistry 2 (2023academic year) Late  - その他

  • Advanced Study (2023academic year) Other  - その他

  • Biotechnology experiment 2 (2023academic year) 1st semester  - 月5~8,木5~8

  • Frontier Materials and Process Engineering (2022academic year) Prophase  - 金1,金2

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  • Seminar on Applied Chemistry 1 (2022academic year) Prophase  - その他

  • Seminar on Applied Chemistry 2 (2022academic year) Late  - その他

  • Research Works for Master Thesis on Applied Chemistry (2022academic year) Year-round  - その他

  • Material Process Experiment 2 (2022academic year) 1st semester  - 月5~8,木5~8

  • Material Process Experiment 2 (2022academic year) 1st semester  - 月5~8,木5~8

  • Material Process Experiment 3 (2022academic year) Third semester  - 火5~8,金5~8

  • Material Process Experiment 3 (2022academic year) Third semester  - 火5~8,金5~8

  • Biotechnology experiment 2 (2022academic year) 1st semester  - 月5~8,木5~8

  • Biotechnology experiment 2 (2022academic year) 1st semester  - 月5~8,木5~8

  • Frontier Materials and Process Engineering (2021academic year) Prophase  - 金1,金2

  • Internship in Applied Chemistry (2021academic year) Prophase  - その他

  • Seminar on Applied Chemistry 1 (2021academic year) Prophase  - その他

  • Seminar on Applied Chemistry 2 (2021academic year) Late  - その他

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  • Material Process Experiment 2 (2021academic year) 1st semester  - 月5,月6,月7,月8,木5,木6,木7,木8

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  • Material Process Experiment 3 (2021academic year) Third semester  - 火5,火6,火7,火8,金5,金6,金7,金8

  • Material Process Experiment 3 (2021academic year) Third semester  - 火5,火6,火7,火8,金5,金6,金7,金8

  • Biotechnology experiment 2 (2021academic year) 1st semester  - 月5,月6,月7,月8,木5,木6,木7,木8

  • Biotechnology experiment 2 (2021academic year) 1st semester  - 月5,月6,月7,月8,木5,木6,木7,木8

  • Frontier Materials and Process Engineering (2020academic year) Prophase  - 金1,金2

  • Internship in Applied Chemistry (2020academic year) Prophase  - その他

  • Seminar on Applied Chemistry 2 (2020academic year) Late  - その他

  • Research Works for Master Thesis on Applied Chemistry (2020academic year) Year-round  - その他

  • Material Process Experiment 2 (2020academic year) 1st semester  - 月4,月5,月6,月7,木4,木5,木6,木7

  • Material Process Experiment 2 (2020academic year) 1st semester  - 月4,月5,月6,月7,木4,木5,木6,木7

  • Material Process Experiment 3 (2020academic year) Third semester  - 火4,火5,火6,火7,金4,金5,金6,金7

  • Material Process Experiment 3 (2020academic year) Third semester  - 火4,火5,火6,火7,金4,金5,金6,金7

  • Biotechnology experiment 2 (2020academic year) 1st semester  - 月4,月5,月6,月7,木4,木5,木6,木7

  • Biotechnology experiment 2 (2020academic year) 1st semester  - 月4,月5,月6,月7,木4,木5,木6,木7

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Media Coverage

  • 過酷環境で使用できるタフネスと自己修復性を両立した高分子イオン液体ゲル材料の開発 Internet

    NEDO  https://wakasapo.nedo.go.jp/seeds/seeds-1714/  2022.5

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  • A rapid flow process that can convert droplets into multilayer polymeric microcapsules Promotional material

    https://www.okayama-u.ac.jp/up_load_files/ebulletin-RUs/pdf/vol99.pdf  2022.3.7

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  • 岡山大など、未利用熱を輸送するバイオベース高分子カプセルを創出 Internet

    国立研究開発法人 国立環境研究所  環境展望台  https://tenbou.nies.go.jp/news/jnews/detail.php?i=33327  2022.2.17

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  • バイオベース高分子を殻材とする蓄熱マイクロカプセルの高速生産 Internet

    岡山大学  https://www.okayama-u.ac.jp/tp/release/release_id923.html  2022.2.17

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  • RSKラジオ 朝耳らじおGoGo 技術の森 TV or radio program

    RSK  2022.2.16

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  • RSKラジオ 朝耳らじおGoGo 技術の森 TV or radio program

    RSK  2022.2.9

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  • 自己多層乳化を用いたマトリョーシカ微粒子の調製 〜油と水を混ぜてすぐ固めるだけ〜 Internet

    Chem-Station  https://www.chem-station.com/chemistenews/2022/01/matryoshka.html  2022.1.18

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  • 自己多層乳化を用いたマトリョーシカ微粒子の調製〜油と水を混ぜてすぐ固めるだけ〜 Internet

    岡山大学  https://www.okayama-u.ac.jp/tp/release/release_id908.html  2021.12.23

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  • 移植細胞を異物反応から守るには、太めのファイバーで包むのが効果的 〜膵島細胞移植による糖尿病マウスの血糖値正常化と移植片の回収に成功〜 Internet

    東京大学生産技術研究所  https://www.iis.u-tokyo.ac.jp/ja/news/3313/  2020.6.17

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  • Diabetic mice improve with retrievable millimeter-thick cell-laden hydrogel fiber Internet

    EurekAlart!  https://www.eurekalert.org/news-releases/766048  2020.6.15

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